Epidemiologic Characteristics, Transmission Chain, and Risk Factors of Severe Infection of COVID-19 in Tianjin, a Representative Municipality City of ChinaPublic Health Published on 2020-05-202022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 95% CI Analysis chain Characteristics China city Cluster collected confirmed case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cases Diagnosis early stage epidemiologic characteristics epidemiological Evidence Factor Gender independent risk factor Infection infections involved Isolation Logistic regression male mechanism median multivariate municipality outbreak Patient Prevent provide reported risk factor Risk factors SARS-CoV-2 Severe COVID-19 Infection Severe infection Symptom symptom onset the epidemic Tianjin Transmission transmission chain Treatment was performed [DOI] 10.3389/fpubh.2020.00198 PMC 바로가기 [Article Type] Public Health
Extended SIR Prediction of the Epidemics Trend of COVID-19 in Italy and Compared With Hunan, ChinaMedicine Published on 2020-05-062022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI applied basic reproductive number blockade chain China coronavirus country COVID-19 COVID-19 cases COVID-19 epidemic develop Effect effective Endpoint epidemics trend European country Extended global public health help infected case Infectious disease Intervention Italy Markov measure Monte Carlo method predict prediction Prevent public health public health measure resulting spread of COVID-19 the epidemic the mean total population trend was used [DOI] 10.3389/fmed.2020.00169 PMC 바로가기 [Article Type] Medicine
Hybridization Chain Reactions Targeting the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Communication Published on 2020-05-012022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] Algorithm base pairs cDNA chain complementary complex coronavirus 2 demonstrated DNA domain Efficiency Evidence facilitate gel electrophoresis help hybridization Hybridization chain reaction IMPROVE isothermal amplification Local loci molecular nucleocapsid Pandemics parameter PCR polymerase chain reaction Reactions respiratory RNase P SARS-CoV-2 SARS–CoV-2 screening strategy secondary structure sequence targeting [DOI] 10.3390/ijms21093216 PMC 바로가기 [Article Type] Communication
Single Chain Fragment Variable (scFv) Antibodies Targeting the Spike Protein of Porcine Epidemic Diarrhea Virus Provide Protection against Viral Infection in PigletsArticle Published on 2019-01-142022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] Administered administration antibody Antigen cause chain cloned contagious coronavirus death diarrhea effective epidemic diarrhea epitope expression fragment higher affinity IFA Infection inhibit intestinal investigated lesions less mild clinical symptoms Mortality Neonatal neutralizing antibody passive immunization PEDV plaque reduction neutralization Plasmid Porcine epidemic diarrhea virus protection protein expression scFv screened selected shown significantly significantly increased single chain fragment variable (scFv) spike (S) protein Support survival rate targeting the Spike the spike protein Treatment variable viral shedding virus [DOI] 10.3390/v11010058 PMC 바로가기 [Article Type] Article
Detection of viral respiratory pathogens in mild and severe acute respiratory infections in SingaporeArticle Published on 2017-02-202022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] Acute respiratory infection added analysed ARI chain clinical Cohort Community declined decrease detection Diagnosis evaluate excluded faster hospital Influenza Inpatient Inpatients Laboratory Mild multiplex Nasopharyngeal swab Older Participants pathogen PCR performed presenting Prospective Study reaction respiratory virus Respiratory virus infections RT-PCR Severe case Singapore Surveillance tested viral pathogen viral respiratory virus [DOI] 10.1038/srep42963 PMC 바로가기 [Article Type] Article
SARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J MiceArticle Published on 2016-06-282022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] acute respiratory syndrome antiviral immune response approach Arthritis Autoimmune cartilage chain coronavirus disease dosage Efficacy evade Evidence fusion fusion peptide Host Host immune response hosts Hypothesis immune immunomodulatory in vivo include incorporation increase Infection involved lipoprotein mice modulate molecular mechanism multichain peptide PROTECT receptor replicate SARS-CoV sequence Signaling significantly suggested Support T cell receptor target TCR therapeutic strategy transferred Viral immune evasion virus [DOI] 10.1038/srep28672 PMC 바로가기 [Article Type] Article
Human Coronaviruses Associated with Upper Respiratory Tract Infections in Three Rural Areas of GhanaResearch Article Published on 2014-07-312022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] Area ARI asymptomatic subject case control study chain children conducted control subjects controls determine GenBank HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 Human human coronavirus Infection infections MERS-CoV Middle East morbidity and mortality no difference occurred Older positive reaction recruited respiratory respiratory syndrome coronavirus respiratory tract infection Result sequence subject Swab tested tract upper upper respiratory tract virus detection viruses [DOI] 10.1371/journal.pone.0099782 PMC 바로가기 [Article Type] Research Article
Real-Time Polymerase Chain Reaction for Detecting SARS Coronavirus, Beijing, 2003Dispatch Published on 2004-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome Beijing chain clinical samples coronavirus detect diagnostic identify Nucleocapsid gene outbreak PCR polymerase chain Quantitative reaction SARS-CoV target to screen viral genome [DOI] 10.3201/eid1002.030799 PMC 바로가기 [Article Type] Dispatch
Real-Time Reverse Transcription–Polymerase Chain Reaction Assay for SARS-associated CoronavirusResearch Published on 2004-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] animal coronavirus application chain coronavirus Culture detect Detection limit diagnosing different Genome genomic Isolation primer probe reaction Real-time PCR real-time RT-PCR Region RT-PCR RT-PCR assay SARS SARS-CoV SARS-CoV infection specimens [DOI] 10.3201/eid1002.030759 PMC 바로가기 [Article Type] Research