clinically – Page 25 – Communicable Diseases Research

COVID-19-Related Retinal Micro-vasculopathy – A Review of Current Evidence

COVID-19 관련 망막 미세혈관병증 - 현재 증거 검토

Review

Published on 2022-03-012022-09-11
Journal: American journal of ophthalmology [Category] SARS, 치료기술,

A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data

Clinical Trial

Published on 2022-03-012022-10-05
Journal: European urology [Category] SARS, 임상,

[키워드] 95% CI 95% confidence interval Acetate affected Air-liquid interface androgen Androgen deprivation therapy antiandrogen Bicalutamide clinical study clinical trial clinically Combination conducted confounders COVID-19 COVID-19 symptoms Culture death Deprivation discharge Effect enrolled enzalutamide epidemiological Epidemiological study epidemiologically evaluate the effect Evidence evidence of hazard ratio higher risk hospital Hospitalization hospitalized COVID-19 patient immune response include intensive care investigated limitation lung cells mechanical ventilation Patient patients treated Phase 2 Primary outcome Prostate cancer Randomized randomized trial required Research Result Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Standard of care Support Testosterone therapeutic effect therapy Treatment Trial virus replication
[DOI] 10.1016/j.eururo.2021.12.013 PMC 바로가기 [Article Type] Clinical Trial

[Review of new evidence about the possible vertical transmission of coronavirus disease-2019]

[코로나바이러스 질병-2019의 수직적 전파 가능성에 대한 새로운 증거 검토]

Review

Published on 2022-03-012022-09-11
Journal: Gaceta sanitaria [Category] SARS, 치료기술,

[키워드] amniotic Amniotic fluid Blood can not Clinical diagnosis clinical sample clinical samples clinically conjunction Contamination Cord blood coronavirus COVID-19 criteria diagnosis of COVID-19 English Evidence guide Health Organization human milk indican infective Isolation management maternal blood membranes nine para patients with COVID-19 peer-reviewed Placenta Placentas positive Protein required RNA SARS-CoV-2 SARS-CoV-2 RNA Sin Spanish systematic review Transmisión vertical Transmission umbilical Umbilical cord umbilical cord blood vertical transmission Viral particles women World Health Organization
[DOI] 10.1016/j.gaceta.2020.06.005 PMC 바로가기 [Article Type] Review

Remitting neuropsychiatric symptoms in COVID-19 patients: Viral cause or drug effect?

COVID-19 환자의 신경 정신병 증상 완화 : 바이러스 성 원인 또는 약물 효과?

Article

Published on 2022-03-012022-09-12
Journal: Journal of medical virology [Category] MERS, SARS, 진단,

Rehabilitation of COVID-19 patients with respiratory failure and critical illness disease in Slovenia: an observational study

Observational Study

Published on 2022-03-012022-10-05
Journal: International journal of rehabilitation research. Internationale [Category] SARS, 임상,

[키워드] acute respiratory syndrome Admission Analysis Care cause clinically clinically suspected coronavirus coronavirus disease COVID COVID-19 patient Critical develop Diagnosis discharge disease Efficiency enrolled functional impedance IMPROVE improvement Independence index Infection limitation measure mechanical ventilation Mobility nutritional status occupational outcome outcome measures Patient patients performance Pneumonia post-COVID-19 patient problem prospective observational study psychologic rehabilitation Respiratory failure SARS-CoV-2 severe malnutrition statistically significant syndrome was performed were assessed were used
[DOI] 10.1097/MRR.0000000000000513 PMC 바로가기 [Article Type] Observational Study

Hybrid closed-loop glucose control compared with sensor augmented pump therapy in older adults with type 1 diabetes: an open-label multicentre, multinational, randomised, crossover study

Randomized Controlled Trial

Published on 2022-03-012022-10-05
Journal: The Lancet. Healthy longevity [Category] 임상,

The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications

SARS-CoV-2의 스파이크 단백질은 헴 옥시게나제-1을 유도합니다: 병태생리학적 의미

Article

Published on 2022-03-012022-09-12
Journal: Biochimica et biophysica acta. Molecular basis of [Category] MERS, SARS, 진단,

[키워드] ACE2 Acute kidney injury adaptive AKI angiotensin-converting enzyme 2 assessment caused Cell cell lines cellular clinically COVID-19 COVID-19 patient Effect enzyme examined expression HEK293 heme Heme oxygenase-1 ICAM1 implication induce inducer kidney Kidney injury major organ MCP-1 nephrotoxic outcome overexpressing Plasmid Protective protein expression provide quercetin reduced response SARS-CoV-2 SARS-CoV-2 spike signaling pathway spike Spike protein Spike protein expression Syncytia syncytia formation TNF-α transfected with transfecting upregulate upregulated Urine Vero E6 cell viral spike protein virus was performed
[DOI] 10.1016/j.bbadis.2021.166322 PMC 바로가기 [Article Type] Article

Integrated hepatic single-cell RNA sequencing and untargeted metabolomics reveals the immune and metabolic modulation of Qing-Fei-Pai-Du decoction in mice with coronavirus-induced pneumonia

통합 된 간 단일 세포 RNA 시퀀싱 및 표적화되지 않은 대사체는 코로나 바이러스-유도 폐렴과 마우스에서 Qing-Fei-Pai-Du 달인의 면역 및 대사 조절을 보여준다.

Article

Published on 2022-03-012022-08-31
Journal: Phytomedicine : international journal of phytother [Category] 유전자 메커니즘, 치료제,

[키워드] alteration Analysis attenuate B cells BALB/c mice best CD4 CD8 clinically Cold Cold-damp environment Combination Control control group coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia COVID-19 patients Cytokines damp environment disease disease-associated exposure to Gene Expression HCoV HCoV-229E human coronavirus IFN-γ IL-6 immune immune function Immunity immunological IMPROVE indicated infecting Infection Inflammation Inflammatory cytokine Inflammatory cytokines knowledge Liver injury liver tissue Lymphocytes mechanism mechanism of action metabolic function metabolism metabolomics mice Model modulate modulation mouse model Mouse models performed Peripheral blood peripheral blood lymphocyte peripheral blood lymphocytes Pneumonia profile purine Qing-Fei-Pai-Du decoction reduce regulated Regulatory reveal RNA RNA sequencing significantly significantly increased Single-cell RNA sequencing status T cells TCM therapy TNF-α transcriptional treat treated Treatment Untargeted metabolomics
[DOI] 10.1016/j.phymed.2021.153922 PMC 바로가기 [Article Type] Article

Reproductive and developmental safety of nirmatrelvir (PF-07321332), an oral SARS-CoV-2 M pro inhibitor in animal models

동물 모델에서 경구용 SARS-CoV-2 M pro 억제제인 니르마트렐비르(PF-07321332)의 생식 및 발달 안전성

Article

Published on 2022-03-012022-09-11
Journal: Reproductive toxicology (Elmsford, N.Y.) [Category] 치료제,

[키워드] administration age animal model Antiviral Clinical studies clinical study clinically coronavirus COVID-19 Critical death developmental during pregnancy Effect Embryo Embryo-Fetal development embryonic embryonic development enhancer evaluated Factor female female fertility Fertility Genetic Genetic toxicity high risk Hospitalization hospitalized patient ICH in viral infected with SARS-CoV-2 information inhibitor lack limit dose M pro male mammalian cells manifestation Nirmatrelvir NMV no effect no effects oral Oral COVID-19 therapy patient population Paxlovid PF-07321332 pharmacokinetic phase Pregnancy Prevent progression protease Protein rabbit RAT Rat. RATs Replication reported reproductive risk Ritonavir SARS-CoV-2 SARS-CoV-2 main protease selective severe disease shown specific protein the SARS-CoV-2 therapeutic option therapeutic target therapy Toxicity viral replication virus
[DOI] 10.1016/j.reprotox.2022.01.006 PMC 바로가기 [Article Type] Article

Instrument-free, CRISPR-based diagnostics of SARS-CoV-2 using self-contained microfluidic system

자급식 미세유체 시스템을 사용하여 기기가 필요 없는 CRISPR 기반 SARS-CoV-2 진단

Article

Published on 2022-03-012022-09-11
Journal: Biosensors & bioelectronics [Category] MERS, SARS, 진단, 치료기술,

[키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 cleavage clinically coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Cas12a Critical detect Device diagnostics Diseases electricity hand Hand warmer Infectious diseases instrument Instrument-free molecular diagnostics isothermal amplification lateral flow molecular Nasopharyngeal swab operation other infectious diseases platform point-of-care Rapid reagent respiratory SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA Self-contained microfluidic chip. sensitivity severe acute respiratory syndrome Coronavirus specificity Treatment
[DOI] 10.1016/j.bios.2021.113865 PMC 바로가기 [Article Type] Article