Critical – Page 25 – Communicable Diseases Research

Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19

심각하거나 치명적인 COVID-19에 대한 숙주 유전자 변이 및 감수성의 임상적 의미

Review

Published on 2022-08-192022-09-11
Journal: Genome Medicine [Category] SARS, 변종, 치료제,

Incidence of thromboembolic complications in hospitalized COVID-19 patients in a medical ward in Japan: A single-center retrospective and prospective observational study

Observational Study

Published on 2022-08-192022-10-05
Journal: Medicine [Category] 임상,

[키워드] 95% CI addition Admission age Asian Asymptomatic body mass index complications of COVID-19 conducted COVID-19 COVID-19 patient Critical determine died events hallmark higher risk hospital hospitalized COVID-19 patient identify incidence intensive care IQR Ischemia Japan Japanese limb median Mild moderate Myocardial infarction occurred Patient Prevalence Primary outcome prospective cohort study prospective observational study Prospective Study retrospective Severe case severe COVID-19 severe COVID-19 patient severity of COVID-19 single-center stroke symptomatic the median thromboembolic complication thromboembolic complications transferred Venous Thromboembolism women
[DOI] 10.1097/MD.0000000000029933 PMC 바로가기 [Article Type] Observational Study

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

Research

Published on 2022-08-182022-10-05
Journal: Nature Medicine [Category] SARS, 변종, 유전자 메커니즘, 치료기술, 치료법, 치료제,

From rare disorders of immunity to common determinants of infection: Following the mechanistic thread

희귀 면역 장애부터 일반적인 감염 결정 요인까지: 기계론적 실마리를 따라

Review

Published on 2022-08-182022-09-11
Journal: Cell [Category] 유전자 메커니즘,

[Comparative study of patients hospitalized for SARS-CoV-2 infection in two consecutive waves in Tunisia]

Article

Published on 2022-08-182022-11-16
Journal: Médecine tropicale et santé internationale [Category] SARS, 변종,

[키워드] acute respiratory distress affected age ARDS average average age cause circulation clinical form Comorbidities consequence coronavirus country COVID COVID-19 COVID-19 patient Critical death Deceased decrease Delta delta variant diabete English epidemic waves epidemiological data Étude Evolution Fatality rate feature forme French Gender global pandemic Health hospital Hospitalization Hospitalized hospitalized patient hypertension in both group intensive care less Maghreb management median multi-organ failure Northern Africa not significant nous Novel coronavirus Patient patients hospitalized prevalent Prospective Study SARS-CoV-2 SARS-COV-2 infection second wave Septic shock significantly significantly higher Sociodemographic successive wave symptoms onset syndrome the patient triggered Tunis Tunisia vaccination
[DOI] 10.48327/mtsi.v2i3.2022.207 PMC 바로가기

Differential gene expression profiling reveals potential biomarkers and pharmacological compounds against SARS-CoV-2: Insights from machine learning and bioinformatics approaches

Article

Published on 2022-08-172022-11-15
Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 치료기술, 치료제,

[키워드] acid approach bioinformatics caused Comorbidities complex interplay Compound contribute coronavirus 2 COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 progression Critical cyclosporine DEGs detect develop differentially expressed gene disease disease pathogenesis dysregulated E2F1 effort EGR1 expressed Factor functional functional enrichment Gene expression profiling Gene regulatory networks Genetic Genomics healthy controls healthy individual humans identify indicated individual individuals insight inter-individual Interaction machine learning approach MAX Mental mental retardation miRNA expression miRNAs nasopharyngeal network analysis offer Ontology overexpressed pandemic pathophysiology pathway pharmacological Potential biomarker Regulatory respiratory responsible reveal RNA-Seq RNA-seq data SARS-CoV-2 SARS-COV-2 infection Spread SRF TFS the SARS-CoV-2 therapeutic option therapeutic target therapeutic targets Vaccine Variability with COVID-19 YY1
[DOI] 10.3389/fimmu.2022.918692 PMC 바로가기

Competing Responses to Global Inequalities in Access to COVID Vaccines: Vaccine Diplomacy and Vaccine Charity Versus Vaccine Liberty

COVID 백신에 대한 접근의 글로벌 불평등에 대한 경쟁적인 대응: 백신 외교 및 백신 자선 단체 대 백신 자유

Review

Published on 2022-08-152022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] 변종,

Clinical and immunological features associated to the development of a sustained immune humoral response in COVID-19 patients: Results from a cohort study

Article

Published on 2022-08-152022-11-15
Journal: Frontiers in Immunology [Category] SARS, 진단,

[키워드] abnormality acute infection acute respiratory syndrome anti-cellular antibodies anti-SARS-CoV-2 IgG antibodies antibody Antibody Response Antiviral baseline blood sample CD8 changes in characterized chemokine chemokines clinical cohort study coronavirus coronavirus disease COVID-19 Critical Critical disease Critical illness cytokine Cytokines defined Diagnosis evaluated feature flow cytometry Follow-up humoral humoral immune response Humoral response IgG IgGs IL-13 IL-2 IL-4 immune Immune profile immunological IP-10 key factor lymphocyte Lymphocytes lymphopenia Measures Neutrophil extracellular trap outcome Patient patients with COVID-19 positive Primary outcome Quantitative recruitment regulatory T cells Research Result SARS-CoV-2 serum serum cytokine Serum level serum titer strongly related sustained T cell T cells the patient variable were assessed
[DOI] 10.3389/fimmu.2022.943563 PMC 바로가기

Lactate Dehydrogenase to Albumin ratio as a Predictive Factor of COVID-19 Patients’ Outcome; a Cross-sectional Study

Article

Published on 2022-08-152022-10-06
Journal: Arch Acad Emerg Med [Category] 진단,

[키워드] 95% CI albumin association AUC can be used Care characteristic confounding variables Coverage COVID-19 COVID-19 mortality Critical cut-off cut-off value dehydrogenase died Emergency emergency service evaluate evaluated Factor Health Health care worker help higher odd hospital Hospitalization hospitalized COVID-19 patient ICU ICU admission identify increase in intensive care Iran L-Lactate Dehydrogenase lactate dehydrogenase management Mortality outcomes Patient patients predict Prognosis regression analysis Retrospective cross-sectional study risk risk stratification ROC Sensitivity and specificity serum albumin severity three group vaccination was used
[DOI] 10.22037/aaem.v10i1.1646 PMC 바로가기 [Article Type] Article

Prognostic impacts of soluble immune checkpoint regulators and cytokines in patients with SARS-CoV-2 infection

Article

Published on 2022-08-152022-11-15
Journal: Frontiers in Immunology [Category] SARS, 바이오마커,

[키워드] Absolute lymphocyte count acute respiratory syndrome Bio-Plex 200 system C-reactive protein (CRP CCL2 chemokine Clinical practice Cluster coronavirus Coronavirus disease 2019 correlated correlation COVID-19 Critical cytokine cytokine level cytokine release Cytokine release syndrome death deaths diagnosed with COVID-19 different time point evaluated examined Factor GM-CSF IL-10 IL-8 immune immune checkpoint Immunoglobulin Impact Increased Infection inflammatory markers involved Laboratory Ligand marker motif multiplexed immunoassay nine pandemic Patient patients with SARS-CoV-2 performed Platelet poor prognosis positive correlation procalcitonin Prognosis prognostic Protein Quantitative SARS-CoV-2 SARS-CoV-2-infected patients serum sample shown significantly higher Stratification survivor Survivors T-cell virus entry were measured
[DOI] 10.3389/fimmu.2022.903419 PMC 바로가기