The impact of the coronavirus disease and Tele-Heart Failure Clinic on cardiovascular mortality and heart failure hospitalization in ambulatory patients with heart failureResearch Article Published on 2021-03-232022-10-28 Journal: PLoS ONE [Category] Coronavirus, SARS, [키워드] ambulatory patient blockade cardiovascular Care chose clinic Cohort continuum coronavirus disease COVID-19 pandemic database death declined dose Ejection fraction failure heart heart failure Hospitalization less Mortality neurohormonal not affect pandemic Patient readmission reduced reduction in rehospitalization Result significantly significantly lower subsequent Therapies [DOI] 10.1371/journal.pone.0249043 PMC 바로가기 [Article Type] Research Article
Bioinformatics and system biology approach to identify the influences of COVID-19 on cardiovascular and hypertensive comorbidities심혈관 및 고혈압 동반 질환에 대한 COVID-19의 영향을 식별하기 위한 생물정보학 및 시스템 생물학 접근Article Published on 2021-03-222022-09-11 Journal: Briefings in Bioinformatics [Category] SARS, 유전자 메커니즘, [키워드] ACE inhibitor ACE inhibitors ACE2 ACE2 gene acute respiratory syndrome acute respiratory syndrome coronavirus Affect aldosterone angiotensin angiotensin converting enzyme angiotensin I Angiotensin II approach bioinformatics blood pressure blood sample Blood samples Cancer cardiovascular cardiovascular comorbidities cardiovascular comorbidity cardiovascular disease cardiovascular diseases caused Cell cell signalling pathway and ontology cell stress cells chemical compound chemokines chronic heart failure Comorbidity condition convert coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytokines DEGs diabetes differentially expressed differentially expressed gene Differentially expressed genes disease Diseases drug elevated enzyme expressed expression functions gene regulatory network Genetic heart heart failure help human tissues hypertension hypertensive hypertensive diseases identify immune response gene immune response genes infect infected individual infected individuals Infection influence Interaction interactions intestine kidneys Lung injury Lungs mechanism medication medications Messenger RNA Mortality ontologies Ontology pandemic Pathogenesis pathway Pathways Patient Peripheral blood peripheral blood cell peripheral blood cells receptor reduce Renin renin-angiotensin-aldosterone system Research risk SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 suggested susceptible System biology T cell target Testis Toll-like receptor Treatment type 2 diabete type 2 diabetes [DOI] 10.1093/bib/bbaa426 PMC 바로가기 [Article Type] Article
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infectionArticle Published on 2021-03-162023-06-15 Journal: Cell [Category] Fulltext, MERS, [키워드] Bromodomain and extraterminal family inhibitors COVID-19 Drug discovery heart Inflammation organoids [DOI] 10.1016/j.cell.2021.03.026 PMC 바로가기 [Article Type] Article
Cardiovascular Disease and COVID-19: Insight From Cases With Heart FailureCardiovascular Medicine Published on 2021-03-152022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Activation Acute myocardial infarction Angiotensin (Ang)-converting enzyme 2 anti-infective drug arise arrhythmia cardiac failure cardiovascular cardiovascular disease cardiovascular system clinical outcomes Clinical treatment complex interaction conditions coronavirus disease COVID-19 death Effect Evidence failure heart heart failure increase indicate Injury insight knowledge patients patients with COVID-19 proportion recent renin-angiotensin system risk Severe infection systemic inflammation Therapeutic strategies treatment for COVID-19 [DOI] 10.3389/fcvm.2021.629958 PMC 바로가기 [Article Type] Cardiovascular Medicine
SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19인간 iPSC 유래 심장 세포의 SARS-CoV-2 감염은 COVID-19 환자의 심장에서 세포변성 특징을 반영합니다Reports Published on 2021-03-152022-09-10 Journal: Science Translational Medicine [Category] MERS, SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alterations Asymptomatic Autopsy autopsy specimens cardiac damage cause Cell consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytopathic damage dysfunction exposure feature heart Human Infection leads morphologic features Morphological nuclear offer Pathogenesis Patient patients patients with COVID-19 platform raise reflect reflected respiratory robust SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe cases specimen stem cell transcriptomic [DOI] 10.1126/scitranslmed.abf7872 PMC 바로가기 [Article Type] Reports
Pulmonary, cardiac and renal distribution of ACE2, furin, TMPRSS2 and ADAM17 in rats with heart failure: Potential implication for COVID‐19 diseaseOriginal Article Published on 2021-03-042022-10-29 Journal: Journal of Cellular and Molecular Medicine [Category] COVID-19, MERS, SARS, [키워드] ACE ACE2 ADAM17 Ang II angiotensin converting enzyme 2 binding domain BNP cell membranes clinical setting compensated component contribute Control controls correlation COVID‐19 Deleterious disease disease severity distribution downregulated ENhance enzyme expression furin group heart heart failure hearts immunoreactivity increased expression isoform kidney lung male mechanism mRNA level oedema overexpressed Patient plasma Potential proportion pulmonary pulmonary dysfunction RAAS receptor remained renal renal system renal tissue SARS‐CoV‐2 SARS‑CoV2 severity sodium staining surgical susceptibility the disease tissue tissue remodelling TMPRSS2 urinary sodium was increased while [DOI] 10.1111/jcmm.16310 PMC 바로가기 [Article Type] Original Article
Cost-effectiveness of a Telemonitoring Program for Patients With Heart Failure During the COVID-19 Pandemic in Hong Kong: Model Development and Data AnalysisOriginal Paper Published on 2021-03-032022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] addition Analysis appear assumption Care caused Cohort cost-effectiveness COVID-19 COVID-19 pandemic demonstrated development Effectiveness failure Health health care avoidance heart heart failure Hong Kong hypothetical management Markov Mobile health Model objective older patient outcome outcome measure Patient performed Perspective Program Result seeking sensitivity analysis Smartphone Telemonitoring threshold threshold value usual care [DOI] 10.2196/26516 PMC 바로가기 [Article Type] Original Paper
Clinical Characteristics and Outcomes in Patients with COVID-19 and Cancer: a Systematic Review and Meta-analysis코로나19 및 암 환자의 임상적 특성 및 결과: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-03-012022-09-12 Journal: Clinical oncology (Royal College of Radiologists ( [Category] SARS, 진단, [키워드] 95% confidence interval addition available data Cancer cancer patient Cancer patients Care changes in Chest China clinical Clinical characteristics co-morbidity computer tomography conducted country COVID-19 database Dyspnoea Evidence Fever Ground glass opacity heart hospitalised patient in-hospital mortality inflammatory markers iterative medRxiv Mortality NIH non-specific outcome oxygen saturation patients with COVID-19 performance status Prevalence primary cancer question random-effects meta-analyses review risk risk of COVID-19 SARS-CoV-2 SARS-COV-2 infection susceptibility Symptom systematic review therapeutic interventions with COVID-19 [DOI] 10.1016/j.clon.2020.11.006 PMC 바로가기 [Article Type] Meta-Analysis
ACE-2-interacting Domain of SARS-CoV-2 (AIDS) Peptide Suppresses Inflammation to Reduce Fever and Protect Lungs and Heart in Mice: Implications for COVID-19 TherapySARS-CoV-2(AIDS) 펩티드의 ACE-2 상호작용 도메인은 염증을 억제하여 발열을 줄이고 마우스의 폐와 심장을 보호합니다: COVID-19 치료에 대한 시사점Article Published on 2021-03-012022-09-12 Journal: Journal of neuroimmune pharmacology : the official [Category] 진단, [키워드] ACE-2 ACE2 Activation activities activity acute respiratory syndrome AIDS angiotensin-converting enzyme 2 Arrhythmias association bind caused cells coronavirus COVID-19 COVID-19 therapy domain effective therapy expression Fever heart host cells human lung IL-6 impairment increase in infectious respiratory illness infiltration of neutrophil inhibit inhibited Interaction intranasal locomotor Lung inflammation Lungs mice mimicking mutated NF-κB peptide reduced SARS-CoV-2 SARS-CoV-2 spike selective spike Spike S1. symptoms of COVID-19 therapeutic Treatment virus strain wild type [DOI] 10.1007/s11481-020-09979-8 PMC 바로가기 [Article Type] Article
Myocardial injury in severe COVID-19: Identification and management중증 COVID-19에서 심근 손상: 식별 및 관리Comment Published on 2021-03-012022-09-11 Journal: Resuscitation [Category] SARS, 치료기술, [키워드] accompanied Acute myocarditis addition balloon pump Blood purification Cardiac arrest Cardiac arrhythmia coronavirus COVID-19 CRRT cytokine Cytokine storm decrease ECMO Ejection fraction extracorporeal membrane oxygenation global pandemic glucocorticoid Health Organization heart heart failure human immunoglobulin identification Immunoglobulin Inflammatory factor inflammatory factors Injury intra-aortic balloon pump involved kidney management marker myocardial injury myocarditis opinion Pneumonia Severe patient severe patients SIGN Support Treatment World Health Organization [DOI] 10.1016/j.resuscitation.2020.11.040 PMC 바로가기 [Article Type] Comment