Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a randomised controlled trialRandomized Controlled Trial Published on 2021-07-292022-10-05 Journal: The European Respiratory Journal [Category] Fulltext, SARS, 임상, [키워드] ACE2 ADAM17 COPD COVID-19 downregulate downregulated epithelial expression implication inhaled corticosteroid LABA Patient randomised controlled trial RCT therapy [DOI] 10.1183/13993003.00130-2021 PMC 바로가기 [Article Type] Randomized Controlled Trial
Comparative effectiveness and safety of 32 pharmacological interventions recommended by guidelines for coronavirus disease 2019: a systematic review and network meta-analysis combining 66 trials2019년 코로나바이러스 질병 가이드라인에서 권장하는 32가지 약리학적 중재의 비교 효과 및 안전성: 66건의 시험을 결합한 체계적인 검토 및 네트워크 메타 분석Meta-Analysis Published on 2021-07-272022-09-11 Journal: Chinese medical journal [Category] meta-analysis, SARS, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus adverse event Antibiotics antiviral agent Antiviral agents assessment Bayesian framework calculated Chinese Chloroquine ClinicalTrials Cochrane Library Comparative coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 cure cure rate development drug effect size Effectiveness Efficacy and safety eight evaluate Evidence followed by global pandemic health problem IFN include increased risk interferon interferons low dose measure moderate Mortality Negative conversion Network meta-analysis Odds ratio other treatments Patient patients with COVID-19 pharmacological intervention pharmacological interventions Primary outcome public health Randomized controlled trial Randomized controlled trials RCT RCTs reduce mortality reduction respiratory risk searched severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 standard care Standard of care systematic review TCM Traditional Chinese medicine Trial Viral was performed [DOI] 10.1097/CM9.0000000000001672 PMC 바로가기 [Article Type] Meta-Analysis
Effect of time and titer in convalescent plasma therapy for COVID-19Article Published on 2021-07-222022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract all-cause mortality benefit clinical benefit conditions convalescent plasma Convalescent plasma therapy Coronavirus Disease (COVID)-19 COVID-19 COVID-19 mortality Critical disease stage disease stages early stage early-stage COVID-19 Effect evaluated Follow-up less Meta-analysis Mortality non-randomized study Patient patients with COVID-19 plasma plasma antibody promote provided randomized clinical trial RCT RCTs recipient reduced risk selected significantly System systematic review systems medicine the disease Treatment Virology [DOI] 10.1016/j.isci.2021.102898 PMC 바로가기 [Article Type] Article
Efficacy of Integrated Traditional Chinese and Western Medicine for Treating COVID-19: A Systematic Review and Meta-Analysis of RCTsCovid-19 치료를위한 통합 된 전통 중국 및 서구 의학의 효능 : RCT의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-082022-08-31 Journal: Frontiers in Public Health [Category] MERS, SARS, 임상, 치료제, [키워드] 1.26 95% CI blood cell C-reactive protein C-reactive protein (CRP Chest CT China Chinese Chongqing clinical symptom Clinical symptoms CNKI coronavirus disease Coronavirus disease 2019 cough count COVID-19 COVID-19 patients CQVIP CRP level database disappearance rate Effect effective Efficacy evaluate fatigue Fever heterogeneity identify IMPROVE inception inclusion criteria Infection Infrastructure integrated Chinese and Western medicine Medicine Meta-analysis Patient patients treated patients with COVID-19 Randomized controlled trial RCT RCTs review risk of bia searched SinoMed Stata software statistical analysis Subgroup analyses subgroup analysis suggested Symptom systematic review therapy Traditional treating Treatment treatment of COVID-19 VIP WBC WBC count Web of Science were used White blood cell [DOI] 10.3389/fpubh.2021.622707 PMC 바로가기 [Article Type] Meta-Analysis
Safety of SARS-CoV-2 vaccines: a systematic review and meta-analysis of randomized controlled trialsSARS-CoV-2 백신의 안전성: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-052022-09-10 Journal: Infectious Diseases of Poverty [Category] 임상, [키워드] 95% CI addition adverse event adverse events Adverse events following immunization approved article candidate clinical trial clinical trials Cochrane Library confidence interval coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine COVID-19 vaccines determine first dose immunization inactivated Inactivated vaccine Local lowest mass vaccination Medical conditions medRxiv Meta-analysis mRNA vaccine no significant differences platform Randomized controlled trial Randomized controlled trials RCT RCTs reported required risk risk ratio risk ratios Safety SARS-CoV-2 second dose significant difference significant differences significantly higher subject supplementary material Surveillance systematic review Tolerance vaccination Vaccine was performed Web of Science [DOI] 10.1186/s40249-021-00878-5 PMC 바로가기 [Article Type] Meta-Analysis
Improvements in clinical signs of Parkinson’s disease using photobiomodulation: a prospective proof-of-concept studyRandomized Controlled Trial Published on 2021-07-022022-10-27 Journal: BMC Neurology [Category] Coronavirus, COVID-19, SARS, [키워드] animal model clinical Clinical sign clinically Cognition Combination COVID-19 disease dynamic balance Effect effective effective therapy Effectiveness expected help home improvement incidence individual intranasal measure mitigate Mobility Motor symptoms neurodegenerative neurons New objective Parkinson’s disease Parkinson’s disease participant Participants Photobiomodulation populations PROTECT randomized placebo-controlled trial Randomly RANK RCT recruited reduce Registered registry Result Safe shown Side effect significance level significantly supplementary material sustained Symptom threshold Treatment Treatment effectiveness treatment period was used were assessed [DOI] 10.1186/s12883-021-02248-y PMC 바로가기 [Article Type] Randomized Controlled Trial
Improvements in clinical signs of Parkinson’s disease using photobiomodulation: a prospective proof-of-concept studyPhotobiomodulation을 사용한 파킨슨 병의 임상 징후 개선 : 전향 적 개념 증명 연구Randomized Controlled Trial Published on 2021-07-022022-09-10 Journal: BMC Neurology [Category] 비임상, [키워드] All participants animal model animal models balance best breath clinical Clinical sign Clinical signs clinically Cognition Combination COVID-19 disease dopaminergic neurons dynamic balance Effect effective effective therapy Effectiveness expected help home improvement Improvements incidence individual intranasal measure mitigate Mobility Motor symptoms neurodegenerative neurons New objective Parkinson’s disease Parkinson’s disease participant Participants Photobiomodulation populations PROTECT randomized placebo-controlled trial Randomly RANK RCT recruited reduce Registered registration number registry Result Safe shown Side effect significance level significantly Signs and symptoms supplementary material sustained Symptom threshold Treatment Treatment effectiveness treatment period was used were assessed Wilcoxon Signed Ranks test [DOI] 10.1186/s12883-021-02248-y PMC 바로가기 [Article Type] Randomized Controlled Trial
Improvements in clinical signs of Parkinson’s disease using photobiomodulation: a prospective proof-of-concept studyRandomized Controlled Trial Published on 2021-07-022022-10-27 Journal: BMC Neurology [Category] COVID-19, [키워드] animal model clinical Clinical sign clinically Cognition Combination COVID-19 disease dynamic balance Effect effective effective therapy Effectiveness expected help home improvement incidence individual intranasal measure mitigate Mobility Motor symptoms neurodegenerative neurons New objective Parkinson’s disease Parkinson’s disease participant Participants Photobiomodulation populations PROTECT randomized placebo-controlled trial Randomly RANK RCT recruited reduce Registered registry Result Safe shown Side effect significance level significantly supplementary material sustained Symptom threshold Treatment Treatment effectiveness treatment period was used were assessed [DOI] 10.1186/s12883-021-02248-y PMC 바로가기 [Article Type] Randomized Controlled Trial
Does hydroxychloroquine still have any role in the COVID-19 pandemic?하이드록시클로로퀸이 COVID-19 전염병에서 여전히 어떤 역할을 합니까?Article Published on 2021-07-012022-09-11 Journal: Expert opinion on pharmacotherapy [Category] SARS, 신약개발, 치료제, [키워드] adoption Antiviral antiviral activity antiviral drug antiviral drugs Area benefit candidate Cardiotoxicity Chloroquine clinical trial clinical trials complex conditions controlled trials COVID-19 COVID-19 pandemic Dexamethasone dosage drug drugs Evidence experiment expert hospitalized patient hospitalized patients Hydroxychloroquine IL-6 IL-6 receptor antagonists immunomodulator immunomodulators in vitro data in vivo Infection Interpretation malaria pharmacokinetics prevention Randomized controlled trial RCT RCTs rheumatological safety profile SARS-CoV-2 severe COVID-19 Support therapeutic Tolerability Treatment widespread [DOI] 10.1080/14656566.2021.1898589 PMC 바로가기 [Article Type] Article
“Vitamin D supplementation and COVID-19 treatment: A systematic review and meta-analysis”Review article Published on 2021-07-012022-10-05 Journal: Diabetes & metabolic syndrome [Category] SARS, 치료법, [키워드] 95% CI 95%CI COVID patient COVID pneumonia COVID-19 disease severity Health ICU admission rate invasive ventilation outcome Patient RCT reduce mortality required Result SARS-CoV-2 significant difference systematic review Topic Total Vitamin D Vitamin-D was done [DOI] 10.1016/j.dsx.2021.102189 [Article Type] Review article