Secondary outcomes – Page 25 – Communicable Diseases Research

Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial

중증 급성 호흡기 증후군이 있는 COVID-19 환자 관리에 대한 중국 전통 의학 Maxingshigan-Weijing의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-12-232022-08-31
Journal: Trials [Category] MERS, SARS, 임상, 치료제,

Evidence-based of conjunctival COVID-19 positivity: An Italian experience: Gemelli Against COVID Group

결막 COVID-19 양성의 증거 기반: 이탈리아 경험: COVID-19에 반대하는 Gemelli

Original Research Articles

Published on 2020-12-232022-09-11
Journal: European Journal of Ophthalmology [Category] MERS, SARS, 치료기술,

[키워드] Against blood chemistry C-reactive protein C-RP Care Chest radiography clinical parameter clinical trials Computed tomography Conjunctiva conjunctival Conjunctival swab conjunctival swabs conjunctivitis coronavirus COVID COVID-19 D-dimer Dyspnea enrolled Eye infection ferritin fibrinogen FIVE four groups group highest Hospitalized impairment Infection Italian Lactate lactate dehydrogenase LDH lowest Nasopharyngeal swab NPs ophthalmologists outcome oxygen oxygen saturation Patient patients hospitalized patients with SARS-CoV-2 Personalized medicine positive precautionary measures pulmonary pulmonary impairment radiologic respiratory Respiratory Coronavirus SARS-CoV-2 SARS-COV-2 infection secondary outcome Secondary outcomes severe acute respiratory coronavirus severe pulmonary impairment significantly statistically Swab swabs tears Transmission Trial registration virus
[DOI] 10.1177/1120672120976548 PMC 바로가기 [Article Type] Original Research Articles

Internal treatment in traditional Chinese medicine for patients with COVID-19 A protocol for systematic review and meta-analysis

COVID-19 환자를 위한 중국 전통 의학의 내부 치료 체계적인 검토 및 메타 분석을 위한 프로토콜

3800

Published on 2020-12-182022-08-31
Journal: Medicine [Category] meta-analysis, 치료제,

[키워드] Accompanying average China Chinese Chinese Biomedical Literature Database conducted Controlled controlled trials Corona COVID-19 COVID-19 patients cure rate cytokine data extraction database disappearance effective intervention Effectiveness English Evidence Hospitalization inception Infrastructure internal internal treatment journal literature Medicine Meta-analysis Mortality occurrence rate outcome patients with COVID-19 Primary outcomes protocol Randomized controlled trial Randomized controlled trials registration number researcher review risk of bia searched secondary Secondary outcomes serum cytokine levels subject Symptom systematic review TCM Traditional Traditional Chinese medicine Treatment Virus Disease Web of Science
[DOI] 10.1097/MD.0000000000023739 PMC 바로가기 [Article Type] 3800

Efficacy and safety of mesenchymal stem cells for the treatment of patients infected with COVID-19: a systematic review and meta-analysis protocol

코로나19 환자 치료를 위한 중간엽줄기세포의 효능 및 안전성: 체계적 고찰 및 메타분석 프로토콜

Article

Published on 2020-12-182022-08-31
Journal: BMJ Open [Category] MERS, meta-analysis, SARS,

[키워드] academic conference adverse events antivirus drug assessment bias risk Biomarker Biomarkers Case series case sery CBM Cell Cell Biology changes in chest pain China Chinese CINAHL CNKI Cochrane Library collected conducted Controlled trial COVID-19 pandemic critical cases data extraction database development Dexamethasone difficulty difficulty breathing dose duration of fever Efficacy and safety eligibility criteria Ethical approval Ethics evaluate Evidence high mortality immunology inception incidence include Infectious diseases Infrastructure journal Laboratory laboratory examination life literature mesenchymal stem cell Meta-analysis Mild moderate moderate to severe Mortality movement MSC MSC therapy Patient patients with COVID-19 peer-reviewed performed pressure Prevent Primary outcome Primary outcomes progression PROSPERO protocol public health Quality of life Randomised controlled trials reduce registration number respiratory searched secondary outcome Secondary outcomes sensitivity analysis service severity Shortness of breath SinoMed speech stem cell strength Symptom System systematic review Therapeutic approach therapy treat Treatment Vaccine ventilator VIP Web of Science
[DOI] 10.1136/bmjopen-2020-042085 PMC 바로가기 [Article Type] Article

Co-Operative Pain Education and Self-management (COPES) Expanding Treatment for Real-World Access (ExTRA): Pragmatic Trial Protocol

Co-Operating Pain Education and Self-management (COPES) 실세계 접근을 위한 치료 확장 (ExTRA): Pragmatic Trial Protocol

Article

Published on 2020-12-122022-09-11
Journal: Pain medicine (Malden, Mass.) [Category] SARS, 임상,

[키워드] access Affair Analysis behavioral therapy Blinding can be used Care chronic chronic musculoskeletal pain chronic pain Chronic Pain. clinician cognitive cognitive behavioral therapy collected COVID-19 Department Depression determine education effective effort Electronic health record evaluate evaluation metrics Factor finding form Health Health care Health care system health record health system implementation intensity Interactive Voice Response Intervention IVR maintain male measure Musculoskeletal Musculoskeletal pain nine Nonpharmacologic Treatment outcome outcomes outperform Pain pain intensity pain interference Patient performed Pragmatic pragmatic trial precedence preference Primary outcome resource secondary Secondary outcomes Self-efficacy Sleep symptom severity synchronous technology therapy Treatment Trial veteran veterans voice
[DOI] 10.1093/pm/pnaa365 PMC 바로가기 [Article Type] Article

Death Cafés for prevention of burnout in intensive care unit employees: study protocol for a randomized controlled trial (STOPTHEBURN)

중환자실 직원의 번아웃 예방을 위한 데스 카페: 무작위 대조 시험(STOPTHEBURN)을 위한 연구 프로토콜

Study Protocol

Published on 2020-12-112022-08-13
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] Administered administration analyzed Anxiety Anxiety Disorder Behavioral symptoms Burnout clinician Clinicians collaboration collected Community conducted control arm COVID-19 Critical care Critically ill Critically ill patient critically ill patients death Death Café Depression effective Enrollment equivalent event events facilitated GAD-7 Generalized Generalized Anxiety Disorder group health problems Healthcare workers hospital ICU include intensive care intensive care unit Intervention inventory leads mental health problems mitigate Moral distress Nurses Occupational stress offer outcome participant Participation patient mortality patient safety physician Prevent Primary outcome provide psychotherapist Qualitative Questionnaires Randomized Randomized controlled trial recruited reduce Reflection score secondary Secondary outcomes social interaction Study protocol subject susceptible syndrome Teledebriefing trauma Trial registration Virtual debriefing vulnerable population Work place retention
[DOI] 10.1186/s13063-020-04929-4 PMC 바로가기 [Article Type] Study Protocol

Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial

성인의 중증 COVID-19 치료를 위한 분무형 계면활성제(COV-Surf): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Randomized Controlled Trial

Published on 2020-12-102022-09-10
Journal: Trials [Category] MERS, SARS, 비임상, 임상,

[키워드] 1080 24 hour 24 hours 48 hour 48 hours ACE2 ADEs administration Adverse adverse event adverse events AEs ALEA All participant All participants allergy alveolar angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 anticipated attending physician bind Blinding block randomization Blood bovine breath buffer calcium cells cellular cholesterol Chronic kidney disease class clinical Clinical improvement clinical trial clinical trials Cohort Combination comparator Compliance Concentration conducted Consent contraindication contributing to Control control arm controls COVID-19 COVID-19 adult patient COVID-19 patients current cytokine Data collection Data monitoring committee death declined defined delivery described Device dialysis discretion dissemination dose drug Effect Efficacy EGFR element Eligible participants end point End-Expiratory Pressure Endotracheal intubation enrolled Enrollment enrolment epithelial Escalation EudraCT evaluate exclusion exclusion criteria expected fatty Fatty acid feasibility free fatty acid Frequency hospital hospitalised hypoxia impair include inclusion criteria index Inflammatory marker inflammatory markers Inflammatory response intensive care intensive care unit Intervention investigator Kidney disease lack liver liver failure Local lung lung lavage mechanical ventilation mechanical ventilator mechanically ventilated patient mechanically ventilated patients mixture Mortality nebulisation number objective Open-label opinion Ordinal Scale other treatment outcome oxidative stress Oxygenation PaO participant Patient PCR PEEP Phosphatidylcholine phosphatidylethanolamine phosphatidylglycerol phosphatidylinositol phospholipid PIP Placebo plasma Pneumothorax Positive end-expiratory pressure Prevent Primary outcome progression Protein protocol pulmonary compliance pulmonary hemorrhage pulmonary ventilation quantification randomisation randomised randomised controlled trial Randomized Randomized controlled trial reached receive recorded recruitment reduction Registered reported Respiratory failure SAEs Sample size SARS-CoV-2 viral load SARS-CoV-2 virus secondary outcome Secondary outcomes Serious Adverse Events severe COVID-19 severity sphingomyelin Stage Standard Standard of care status Study protocol subject supplementary material surface tension surfactant synthesis tension the WHO tissue damage total sample size tracheal tracheal aspirate Tracheal aspirates transfer Treatment Trial Trial Steering Committee turnover unique university University College London usual standard of care Ventilation Ventilation Index ventilatory support VFD vibrating mesh nebulizer Viral Viral load virus water website weight with COVID-19 worsening
[DOI] 10.1186/s13063-020-04944-5 PMC 바로가기 [Article Type] Randomized Controlled Trial

Core warming of coronavirus disease 2019 (COVID-19) patients undergoing mechanical ventilation—A protocol for a randomized controlled pilot study

기계 환기를 받는 코로나바이러스 질병 2019(COVID-19) 환자의 코어 온난화 - 무작위 통제 파일럿 연구를 위한 프로토콜

Randomized Controlled Trial

Published on 2020-12-012022-09-12
Journal: PLoS ONE [Category] MERS, 임상, 진단,

[키워드] 1:1 30-Day mortality acute respiratory distress acute respiratory distress syndrome adaptive antipyretics caused clinical benefit clinical benefits core coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 treatment Critical care effect size effective therapy elevated temperature estimate facilitate Fever FiO2 globe heat exchanger hospital include initial initial stages initiation of treatment intensive care Lower respiratory tract management means mechanical ventilation objective outcome PaO2/FiO2 ratio Patient patients patients with COVID-19 pilot study Primary outcome Protective protocol Randomized randomized clinical trial receive registration number respiratory respiratory distress Respiratory failure Result SARS-CoV-2 secondary Secondary outcomes severity Stage Standard-of-care Support surgical syndrome temperature treated Treatment Viral Viral load virus
[DOI] 10.1371/journal.pone.0243190 PMC 바로가기 [Article Type] Randomized Controlled Trial

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial

COVID-19로 입원한 환자의 14일째 임상 상태에 대한 하이드록시클로로퀸의 효과: 무작위 임상 시험

Randomized Controlled Trial

Published on 2020-12-012022-09-25
Journal: JAMA [Category] 임상, 진단, 치료제,

[키워드] 28-day mortality 7-category ordinal scale absolute difference activities acute respiratory syndrome adjusted odds ratio Adults adults hospitalized analyzed assigned blinded clinical clinical status conducted coronavirus coronavirus disease COVID-19 Day death determine died discharged doses duration of symptom Effect Efficacy enrolled extracorporeal membrane oxygenation greater groups hospital Hospitalized Hydroxychloroquine hydroxychloroquine group IMPROVE Infection intensive care interim analysis interquartile range Invasive mechanical ventilation median median age multicenter multivariable nasal Noninvasive ventilation outcome Patient patients Placebo placebo group placebo-controlled randomized trial positive Primary outcome randomization Randomized Randomly receiving Respiratory illness respiratory symptom Sample size secondary outcome Secondary outcomes significantly status supplemental oxygen Support the placebo group Treatment Trial use of hydroxychloroquine with COVID-19
[DOI] 10.1001/jama.2020.22240 PMC 바로가기 [Article Type] Randomized Controlled Trial

Traditional Chinese medicine formula Xiaoqinglong decoction for cough caused by COVID-19 A protocol for a systematic review and meta-analysis

COVID-19로 인한 기침에 대한 중국 전통 의학 공식 Xiaoqinglong 달인 체계적인 검토 및 메타 분석을 위한 프로토콜

Meta-Analysis

Published on 2020-11-252022-08-31
Journal: Medicine [Category] SARS, 임상, 치료제,

[키워드] appearance approval Assessing Biology can not caused China Chinese Chinese Biomedical Literature Database Chongqing Cochrane Library complementary medicine conducted cough coughing COVID-19 data extraction database Disc effective intervention Effectiveness English Ethics Evidence Formal Hospital stay Infrastructure literature Medicine Meta-analysis OVID Patient peer-reviewed Primary outcome protocol Randomized controlled trial Randomized controlled trials registration number researcher risk of bia Science searched secondary outcome Secondary outcomes subject systematic review technology Traditional Chinese medicine VIP Web of Science
[DOI] 10.1097/MD.0000000000023261 PMC 바로가기 [Article Type] Meta-Analysis