Prevalence and predictors of death and severe disease in patients hospitalized due to COVID-19: A comprehensive systematic review and meta-analysis of 77 studies and 38,000 patientsCOVID-19로 인해 입원한 환자의 사망 및 중증 질환의 유병률 및 예측인자: 77건의 연구 및 38,000명의 환자에 대한 포괄적인 체계적 검토 및 메타 분석Research Article Published on 2020-12-072022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] 95% CI adjusted adverse outcome adverse outcomes analyzed association China Chronic kidney disease chronic liver disease CKD CLD Comorbidities confidence interval COPD COVID-19 COVID-19 patient death determine diabete diabetes died disease Disease progression Europe fatality Health health screening heart disease heterogeneity Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients hypertension Inclusion inclusion criteria individual Infection Kidney disease male males Meta-analysis morbidity morbidity and mortality objective observational studies observational study Patient patients hospitalized predictor Prevalence Public reduce Relative risk Result risk risk factor Risk factors searched severe disease smoking susceptibility susceptibility to infection systematic review Web of Science [DOI] 10.1371/journal.pone.0243191 PMC 바로가기 [Article Type] Research Article
Association of Cigarette Smoking, COPD, and Lung Cancer With Expression of SARS-CoV-2 Entry Genes in Human Airway Epithelial CellsMedicine Published on 2020-12-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% confidence interval ACE2 ACE2 (Angiotensin Converting Enzyme-2) affecting Analysis calculated cathepsin L cathpesin L Cell changes in chronic obstructive cigarette CIs contribute COPD COVID-19 decreased expression dependent on effect size effective eligible epithelial cell examined expression expression of SARS-CoV-2 expression profile Genes GEO database GEO dataset healthy control Human human airway epithelial human airway epithelial cells identify increased expression lung cancer mean difference membrane fusion Meta-analysis Patient performed potential risk primary human airway pulmonary disease reduce RStudio SARS-CoV-2 SARS-CoV-2 entry smoker Smokers smoking smoking status TMPRSS2 transcriptomic data transmembrane serine protease 2 was performed [DOI] 10.3389/fmed.2020.619453 PMC 바로가기 [Article Type] Medicine
Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection코로나19 의심환자 1054명 내원한 성인 1054명의 임상적 특징, 증상 및 결과: SARS-CoV-2 감염 여부 비교Article Published on 2020-12-012022-09-11 Journal: The Journal of Infection [Category] MERS, SARS, 진단, 치료기술, [키워드] 95%CI Anosmia Atypical Bacteria Characteristics characteristics of patient clinical Clinical characteristics Cohort Comorbidities Comparator group COPD COVID-19 COVID-19 patient COVID-19 patients Ethnicity First wave healthcare healthcare worker Healthcare workers hospital hospitalised invasive ventilation Laboratory lack molecular MOST negative patients non-randomised trial outcome outcomes pandemic Patient patient data point-of-care positive presenting reported respiratory respiratory virus respiratory viruses RT-PCR SARS-CoV-2 SARS-COV-2 infection smoker Smokers Symptom Symptoms tested These data viruses was obtained white with COVID-19 [DOI] 10.1016/j.jinf.2020.09.033 PMC 바로가기 [Article Type] Article
Addressing Reduced Laboratory-Based Pulmonary Function Testing During a PandemicReview Published on 2020-12-012023-06-19 Journal: Chest [Category] MERS, [키워드] Asthma COPD COVID-19 pandemic Pulmonary function test review SARS-CoV-2 [DOI] 10.1016/j.chest.2020.06.065 PMC 바로가기 [Article Type] Review
Pre-hospital lowest recorded oxygen saturation independently predicts death in patients with COVID-19Service Evaluation Published on 2020-12-012022-10-27 Journal: British Paramedic Journal [Category] COVID-19, [키워드] absence age analysed COPD coronavirus coronavirus disease COVID-19 COVID-19 patients death died discharge discharged distress Gender hospital hypoxia In-hospital in-hospital mortality increasingly independent Inpatient IQR Laboratory Local Lower lowest management Mortality NEWS2 outcome oxygen saturation Patient patients patients with COVID-19 predict predicted recorded reduction in Respiratory failure retrospective risk factor score those who survived Triage [DOI] 10.29045/14784726.2020.09.5.3.59 PMC 바로가기 [Article Type] Service Evaluation
Risk Factors on the Progression to Clinical Outcomes of COVID-19 Patients in South Korea: Using National DataArticle Published on 2020-11-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, [키워드] abnormal hemoglobin Admission age analyzed Blood blood variables BMI Body body temperature Cancer Characteristics chi-square test chronic Chronic kidney disease clinical Comorbidities Comorbidity Control COPD Corona cough COVID COVID-19 COVID-19 patient COVID-19 patients death Dementia Diabetes Mellitus disease Dyspnea epidemiological Factor fatigue Fever headache high risk hospital Hospitalization hypertension ICU increased the risk index initial initial symptom intensive care unit Logistic regression analysis lymphocyte male management mass Multiple regression National Older age Patient performed Platelets predictor prevention proceed progression provided pulmonary rhinorrhea risk factor severe COVID-19 severity sore throat South sputum Stage variable vital signs were used White blood cell [DOI] 10.3390/ijerph17238847 PMC 바로가기 [Article Type] Article
Moving singing for lung health online in response to COVID-19: experience from a randomised controlled trialCOVID-19에 대응하여 폐 건강을 위한 온라인 노래 이동: 무작위 대조 시험의 경험Randomized Controlled Trial Published on 2020-11-252022-08-09 Journal: BMJ Open Respiratory Research [Category] 임상, [키워드] ABC ABC scale points actigraphy activity adaptation Anxiety Anxiety Disorder assessment Attendance balance balance confidence benefit biopsychosocial benefits blind breathlessness chronic obstructive chronic obstructive pulmonary disease chronic obstructive pulmonary disease (COPD) complementary medicine conducted confidence controls COPD COPD Assessment Test score COVID-19-related physical distancing COVID-19-related physical distancing measures Depression digital barrier digital barriers digital facilitator digital facilitators disease Dyspnoea exercise experience face-to-face sessions facilitator facilitators finding FIVE form Generalised anxiety disorder Generalised Anxiety Disorder-7 Health help identify improvement Improving include key consideration key considerations life long-term respiratory conditions lung Lung disease Measures Medical Research Council nine obstructive pulmonary disease online delivery online group singing online sessions participant Participation participation in SLH people with COPD PHQ-9 physical activity physical distancing measures Pilot quantitative data Pilot quantitative outcome Pilot quantitative outcomes pilot study postmeasure postmeasures premeasure premeasures Proactive pulmonary disease Quality of life randomised controlled randomised controlled trial reducing reported Research respiratory Result semistructured interview semistructured interviews setup Seven singing singing group singing groups suggested survey Test thematic analysis Treatment Trial usual care [DOI] 10.1136/bmjresp-2020-000737 PMC 바로가기 [Article Type] Randomized Controlled Trial
Risk for COVID-19 infection in patients with tobacco smoke-associated cancers of the upper and lower airwayReview Article Published on 2020-11-202022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, MERS, SARS, [키워드] ACE2 Activation advanced age airway Cancer cerebrovascular diseases characterized chronic inflammation chronic obstructive clinical Clinical course Clinical outcome Comorbidity condition COPD COVID-19 COVID-19 infection COVID-19 patient cytokine cytokine release epithelial Factor Gender Head neck cancer iatrogenic IL-6 immune Immunity impairment increased risk Infection Inflammation inflammatory cell Interaction interleukin-6 key factor lower airway lung cancer male morbidity and mortality Multi-organ damage nasal occur overexpressed pathophysiological Patient Patients with cancer receptors respiratory cell Respiratory disease respiratory infectious disease Result review risk Risk factors SARS-CoV-2 replication smoker Smokers syndrome the cytokine storm TMPRSS2 tobacco smoke triggering viral infection [DOI] 10.1007/s00405-020-06456-z PMC 바로가기 [Article Type] Review Article
Hospital admissions during Covid-19 lock-down in Germany: Differences in discretionary and unavoidable cardiovascular eventsResearch Article Published on 2020-11-202022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Activation Admission Admissions Cardiopulmonary cardiovascular event consecutive patient COPD CPR defined difference driven by event exacerbated examined Examining Frame Germany greater heart failure Hospitalization initial Italy Laboratory lock-down period Myocardial infarction nine pandemic Patient provided reduction reduction in reported Result stroke the United State treated unstable angina [DOI] 10.1371/journal.pone.0242653 PMC 바로가기 [Article Type] Research Article
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbiditiesReview Article Published on 2020-11-092022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] ACE2 ACE2 expression acute respiratory syndrome addressed angiotensin-converting enzyme 2 cardiovascular disease cause CD147 Comorbidities Comorbidity COPD coronavirus COVID-19 Critical diabetes disease entry receptor Evidence evidence of Factor GRP78 highlighting hypertension implication knowledge limitation manifestation obesity outcome outcomes Pathogenesis receptor receptors SARS-CoV-2 SARS-CoV-2 entry receptor SARS-COV-2 infection sialic acid smoking status Transmission virus [DOI] 10.7554/eLife.61390 PMC 바로가기 [Article Type] Review Article