Polyanhydride nanovaccine against swine influenza virus in pigsArticle Published on 2017-02-222023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] Immunity intranasal PIGS Polyanhydride nanoparticles swine influenza virus [DOI] 10.1016/j.vaccine.2017.01.019
Shigellosis murine model established by intraperitoneal and intranasal route of administration: a comparative comprehension overviewarticle Published on 2017-01-312024-09-01 Journal: Microbes and Infection [Category] 세균성이질, [키워드] Comparative intranasal intraperitoneal murine model pathophysiology Shigellosis [Article Type] article
Inoculation of Goats, Sheep, and Horses with MERS-CoV Does Not Result in Productive Viral SheddingArticle Published on 2016-08-192022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] clinical disease contribute discharge Dromedary goat horse humans in vitro experiment inoculation intranasal MERS MERS-CoV Middle East nasal neutralizing antibody Reservoir host respiratory syndrome coronavirus Result seropositive severe disease shedding sheep Viral transmission virus [DOI] 10.3390/v8080230 PMC 바로가기 [Article Type] Article
Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-CoronavirusResearch Article Published on 2015-12-232022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] accompanied addition animal model antiviral agent Autopsy Brain cause damage Dipeptidyl peptidase 4 Efficacy evaluate exhibited expressing hDPP4 high mortality Human Infection Injury intranasal kidney liver lung Lungs Macrophage infiltration mechanism MERS-CoV MERS-CoV infection mice Middle East Mild Multi-organ damage Neuron neutrophil organ paralysis Pathogenesis peptidase positive Post-infection receptor respiratory Respiratory failure severe pneumonia spleen Symptom systemic inflammation the disease Transgenic mouse Vaccine viral burden viral replication [DOI] 10.1371/journal.pone.0145561 PMC 바로가기 [Article Type] Research Article
Mannan adjuvants intranasally administered inactivated influenza virus in mice rendering low doses inductive of strong serum IgG and IgA in the lungResearch Article Published on 2015-02-262023-05-25 Journal: BMC Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] adjuvant Dose-sparing H1N1 IgA immunisation Influenza intranasal mannan mucosal immunity Vaccine [DOI] 10.1186/s12879-015-0838-7 PMC 바로가기 [Article Type] Research Article
Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigenArticle Published on 2014-09-152023-06-25 Journal: Vaccine [Category] 신종인플루엔자, [키워드] hemagglutinin intranasal Nonspreading Rift Valley fever virus Vaccine vector [DOI] 10.1016/j.vaccine.2014.07.051
Infection with MERS-CoV Causes Lethal Pneumonia in the Common MarmosetResearch Article Published on 2014-08-212022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] addition Analysis animal model cause common Comorbidities comparable complicate demonstrated different time point Dipeptidyl peptidase 4 disease Disease model Efficacy evaluate expression Extensive humans immune inflammatory pathways Interaction intranasal lack lesion lethal lung marmoset marmoset model MERS-CoV MERS-CoV infection Middle East Mild modeling moderate disease MOST ocular Pathogenesis post inoculation potential therapeutic agent predicted Protein receptor required respiratory syndrome coronavirus rhesus RNAseq robust severe disease severe pneumonia severity spike glycoprotein the disease translated treated treatment strategy Vaccine Viral load virus entry was tested while [DOI] 10.1371/journal.ppat.1004250 PMC 바로가기 [Article Type] Research Article
Intranasally administered Endocine formulated 2009 pandemic influenza H1N1 vaccine induces broad specific antibody responses and confers protection in ferretsArticle Published on 2014-05-302023-06-25 Journal: Vaccine [Category] 신종인플루엔자, [키워드] adjuvants Computed tomography ferret influenza vaccine intranasal [DOI] 10.1016/j.vaccine.2014.03.061
Phase I/II trial of a replication-deficient trivalent influenza virus vaccine lacking NS1Clinical Trial Published on 2013-12-162023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] Influenza intranasal live-attenuated NS1 reverse genetics trivalent [DOI] 10.1016/j.vaccine.2013.10.061 [Article Type] Clinical Trial
Recombinant parainfluenza virus 5 vaccine encoding the influenza virus hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c miceArticle Published on 2013-01-012022-10-06 Journal: Journal of Virology [Category] 진단, [키워드] administration Antigen approach BALB/c BALB/c mice booster contraindication different effectively controlled Efficacy ENCODE expressing H5N1 highly pathogenic immune responses immunization inactivated Infection Influenza Influenza virus intramuscular intramuscular vaccination intranasal lung mucosal IgA response Neutralizing New pandemic parainfluenza virus Prevent PROTECT Protective recombinant required robust serum antibody response shown single vaccine tested the vaccine threat vaccination Vaccine Vaccine development Vaccines virion Virology virus virus replication viruses while [DOI] 10.1128/JVI.02330-12 PMC 바로가기 [Article Type] Article