monocyte – Page 26 – Communicable Diseases Research

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Echinacea purpurea (L.) 단핵구의 Moench 처리는 강장제 인터페론 신호 전달, 선천 면역 유전자 발현 증가 및 내인성 레트로 바이러스 서열의 DNA 반복 과메틸화 침묵을 촉진합니다

Research Article

Published on 2021-05-122022-09-10
Journal: BMC Complementary Medicine and Therapies [Category] SARS, 유전자 메커니즘, 치료제,

Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity

Research

Published on 2021-05-102022-10-05
Journal: Nature cell biology [Category] 바이오마커, 치료기술,

Parameters associated with diagnosis of COVID‐19 in emergency department

응급실에서 COVID-19 진단과 관련된 매개변수

Observational Study

Published on 2021-05-072022-09-12
Journal: Immunity, Inflammation and Disease [Category] 임상, 진단,

[키워드] blood cell C‐reactive protein calcium characterized clinician coronavirus disease COVID‐19 COVID‐19 infection COVID‐19 patients Data collection Diagnosis differential diagnose differential diagnosis ED electronic medical record electronic medical records enrolled facilitate heart failure help highlighting identify Laboratory laboratory characteristics Lactate lactate dehydrogenase Lower lymphocyte monocyte neutrophil NLR normal range objective Occurrence Odds ratio other variables parameter parameters Patient Platelet Platelet count Pneumonia procalcitonin radiological Radiological parameters recruited Respiratory disease Result retrospective SARS‐COV2 Sepsis Sepsis disease serum calcium sodium troponin I White blood cell
[DOI] 10.1002/iid3.440 PMC 바로가기 [Article Type] Observational Study

Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection

갈렉틴-9, 사이토카인 방출 증후군의 플레이어이자 SARS-CoV-2 감염의 대리 진단 바이오마커

Comparative Study

Published on 2021-05-042022-08-31
Journal: mBio [Category] SARS, 바이오마커, 치료기술,

[키워드] activated Alpha baseline Biomarker C-reactive protein C-reactive protein (CRP characteristic chemokine chemokines clinical clinical evidence correlation COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients cytokine Cytokine release syndrome Cytokine storm Cytokines diagnostic downregulation Evidence expression Galectin-9 growth factor HCs healthy control healthy controls IL-6 immune activation impacted implicated in vitro indicated individual interleukin interleukin-6 inverse correlation IP-10 MCP-1 MIP-1α monocyte Monocytes Mortality Necrosis neutrophil Neutrophils NK cell NK cells outbreak phenotype plasma positive correlation proinflammatory proinflammatory cytokines proinflammatory mediator proinflammatory mediators receiver operating characteristic Release ROC SARS-CoV-2 SARS-COV-2 infection surrogate TGF-β Therapeutic approach TNF-α transforming growth factor treated Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha
[DOI] 10.1128/mBio.00384-21 PMC 바로가기 [Article Type] Comparative Study

Immunological Biomarkers of Fatal COVID-19: A Study of 868 Patients

치명적인 COVID-19의 면역학적 바이오마커: 868명의 환자에 대한 연구

Immunology

Published on 2021-05-032022-09-11
Journal: Frontiers in Immunology [Category] SARS, 바이오마커,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age Analysis B-cell B-cells Biomarker Biomarkers characterized circulating cohorts Comorbidities conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient COVID-19 patients feature flow cytometry healthy donor healthy donors identify immune immune response immune responses immunotype independent Infection infections lymphopenia monocyte Monocytes multidimensional Multivariate analysis neutrophil Neutrophils non-classical monocyte Non-classical monocytes outcome Patient patients percentage Peripheral blood peripheral blood samples Plasma cells Predictive presenting profile Prognostic factor reduced respiratory risk of death SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe disease significantly significantly lower survival Unsupervised clustering
[DOI] 10.3389/fimmu.2021.659018 PMC 바로가기 [Article Type] Immunology

Monocyte CD169 expression in COVID-19 patients upon intensive care unit admission

중환자실 입원 시 COVID-19 환자의 단핵구 CD169 발현

Observational Study

Published on 2021-05-012022-09-11
Journal: Cytometry. Part A : the journal of the Internation [Category] SARS, 바이오마커, 임상,

Single-cell multi-omics analysis of the immune response in COVID-19

COVID-19의 면역 반응에 대한 단일 세포 다중 오믹스 분석

Article

Published on 2021-04-202022-09-10
Journal: Nature Medicine [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술,

[키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration alveolar alveolar macrophage Analysis Antigen antigen receptor B lymphocyte blood immune cell blood sample Blood samples C1QA cause CD16 CD34 CD8 Cell cellular component characterized circulating Cohort complement contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pathogenesis cross-sectional disease disease severity effector memory effector T cell effector T cells expansion expressing follicular Haematopoiesis helper T cell hematopoietic progenitor cell highlight IgA2 Immune cell immune cells immune response individuals with COVID-19 Infection lymphocyte Macrophage megakaryopoiesis memory T cells Mild Mild disease monocyte Monocytes mononuclear cell mononuclear cells Patient performed Peripheral blood Peripheral blood mononuclear cells Plasma cells plasmablast plasmablasts Platelet platelet activation Platelets predicted proteome proteomic provide receptor reveal RNA sequencing SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe disease severity single-cell symptomatic disease T cell T cells therapy transcript Transcriptome Viral viral infection viral infections
[DOI] 10.1038/s41591-021-01329-2 PMC 바로가기 [Article Type] Article

Clinical characteristics of Egyptian male patients with COVID‐19 acute respiratory distress syndrome

이집트 남성 코로나19 급성호흡곤란증후군 환자의 임상적 특징

Research Article

Published on 2021-04-162022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alanine alanine aminotransferase ALT Analysis ARDS aspartate Aspartate aminotransferase association AST Biomarker Biomarkers blood biochemistry Blood routine C‐reactive protein can be used caused Characteristics clinical Clinical characteristics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 severity COVID‐19 creatinine CRP D-dimer D‐dimer disease severity ferritin ferritin levels groups hemoglobin information involved Laboratory Lactate lactate dehydrogenase LDH lymphopenia male material monocyte monocyte count not significantly different objective parameter Participants Patient patients Platelet Platelet count predict RBC RBC count reported respiratory respiratory distress Result SARS-CoV-2 Serum ferritin severe acute respiratory syndrome Coronavirus Severe case severe cases severity syndrome the disease thrombotic
[DOI] 10.1371/journal.pone.0249346 PMC 바로가기 [Article Type] Research Article

Aging and monocyte immunometabolism in COVID-19

Editorial

Published on 2021-04-152022-10-28
Journal: Aging (Albany NY) [Category] COVID-19, SARS,

[키워드] aging COVID-19 immunometabolism immunosenescence inflammaging monocyte Monocytes
[DOI] 10.18632/aging.202918 PMC 바로가기 [Article Type] Editorial

Single-Cell RNA Sequencing Analysis of the Immunometabolic Rewiring and Immunopathogenesis of Coronavirus Disease 2019

2019년 코로나바이러스 질병의 면역대사 재배선 및 면역병인에 대한 단일 세포 RNA 시퀀싱 분석

Immunology

Published on 2021-04-142022-09-11
Journal: Frontiers in Immunology [Category] MERS, 바이오마커, 유전자 메커니즘, 진단,

[키워드] antibody secretion ATP13A3 ATP6V1B2 biological processe CD14 Cell cell population cell survival change contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Degradation differentiation elevated exacerbated expressed feature Glycolysis hyperinflammation Immune cell immune cells immune dysfunction Inflammation inhibit investigated involved KMT2E LDHA lead lysine mechanism memory B cell memory B cells metabolic changes mild patients mono monocyte Monocytes mononuclear cell mononuclear cells NSD1 Pathways Patient PBMCs Peripheral blood Peripheral blood mononuclear cells PGD PKM Plasma cell Plasma cells plasmablast plasmablasts progression promoted reduced RNA sequencing data SETD2 severe COVID-19 severe disease Severe patient severe patients signaling pathways Single-cell RNA sequencing survival TKT Transcription
[DOI] 10.3389/fimmu.2021.651656 PMC 바로가기 [Article Type] Immunology