Secondary outcomes – Page 26 – Communicable Diseases Research

Interferon β-1a (IFNβ-1a) in COVID-19 patients (INTERCOP): study protocol for a randomized controlled trial

COVID-19 환자의 인터페론 β-1a(IFNβ-1a)(INTERCOP): 무작위 대조 시험을 위한 연구 프로토콜

Study Protocol

Published on 2020-11-232022-08-13
Journal: Trials [Category] SARS, 임상,

Wide-awake local anaesthesia no tourniquet (WALANT) vs regional or general anaesthesia for flexor tendon repair in adults: protocol for a systematic review and meta-analysis

성인의 굴곡건 수복을 위한 WALANT(광각성 국소마취 무지혈대) 대 국소 또는 전신 마취: 체계적인 검토 및 메타 분석을 위한 프로토콜

Protocol

Published on 2020-11-212022-08-31
Journal: Systematic Reviews [Category] Coronavirus, meta-analysis, SARS,

[키워드] (epinephrine Abstract Adrenaline Aerosol generation anaesthesia Anaesthetics approach article best CINAHL clinical trial Cochrane Library comparator complications conducted conscious COVID-19 database determine epinephrine evaluate Evidence feasible Finger injuries Flexor tendon Flexor tendon injury flexor tendons functional general anaesthesia Grey Grey literature hand Hand injuries hand surgery healthcare professionals help IMPROVE include Injury intubation investigator knowledge language limitation Local Meta-analysis Methodological quality motion occur open operative time outcome outcome measures Patient peer review Penetrating penetrating injury Potential Primary outcome protocol random effect range of motion reduced reduced risk Referral Registered removal repair required resolved resource risk secondary Secondary outcomes spread to standard treatment Study protocol supplementary material surgeon surgery surgical systematic review Tendon injuries tourniquet undergo WALANT Wide-awake Wide-awake local anaesthesia no tourniquet wrist
[DOI] 10.1186/s13643-020-01532-1 PMC 바로가기 [Article Type] Protocol

Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)

코로나19 예방 백신: 개별 환자 데이터를 포함하는 네트워크 메타 분석을 통한 살아있는 체계적인 검토를 위한 프로토콜(The LIVING VACCINE Project)

Protocol

Published on 2020-11-202022-09-10
Journal: Systematic Reviews [Category] COVID-19, meta-analysis, SARS,

[키워드] active placebo acute respiratory syndrome acute respiratory syndrome coronavirus aggregate data meta-analyses all age groups all-cause mortality analyzed approach assessment assessments best cause CENTRAL certainty certainty of evidence Clinical research clinical trial registries clinical trial registry clinical trials confidence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database dendritic dendritic cell described development Diagnosis disease Effect events Evidence GRADE identify inactivated include individual patient data meta-analyses life Messenger RNA meta-analyses Mortality network Network meta-analysis non-serious adverse non-serious adverse events not limited observational studies observational study once a week outcome pandemic participant patient data Placebo prevalent Prevent Primary outcomes Protein Protein subunit protocol Quality of life randomized clinical trial randomized clinical trials Research respiratory risk of bia SARS-CoV-2 secondary Secondary outcomes Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread standard care supplementary material systematic review Trial trial sequential analyses Vaccine vaccine for COVID-19 Vaccines Viral Viral vector
[DOI] 10.1186/s13643-020-01516-1 PMC 바로가기 [Article Type] Protocol

A one-year hospital-based prospective COVID-19 open-cohort in the Eastern Mediterranean region: The Khorshid COVID Cohort (KCC) study

Research Article

Published on 2020-11-052022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] Admission age analyzed average cause change clinical symptom Complete Contact COVID COVID-19 COVID-19 cases COVID-19 patient death defined diabete Diagnosis discharge disorder dry cough Eastern Mediterranean Region fatigue Fever Follow-up Health Service Healthcare professional hospital hypertension indicated infected patient information intensive care ischemic heart disease Khorshid lymphopenia management mechanical ventilation Model most prevalent comorbidity outbreak pandemic Patient patients died primary composite endpoint Psychological Pulmonary function recruitment resource Respiratory function rising risk scattering Secondary outcomes Support Symptoms Treatment variables zone
[DOI] 10.1371/journal.pone.0241537 PMC 바로가기 [Article Type] Research Article

Burden of diabetes mellitus and its impact on COVID-19 patients: A meta-analysis of real-world evidence

당뇨병의 부담과 COVID-19 환자에 대한 영향: 실제 증거에 대한 메타 분석

Meta-Analysis

Published on 2020-11-012022-09-11
Journal: Diabetes & metabolic syndrome [Category] 임상,

The efficacy of Siddha Medicine, Kabasura Kudineer (KSK) compared to Vitamin C & Zinc (CZ) supplementation in the management of asymptomatic COVID-19 cases: A structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-10-272022-10-29
Journal: Trials [Category] Coronavirus, MERS, SARS,

[키워드] 1:1 accompany addition adverse effect Asymptomatic Asymptomatic COVID-19 baseline blinded breathlessness bronchial asthma calculated carried Chain Reaction changes in Chennai clinical clinical assessment clinical trial co-morbidity college control group cough COVID COVID-19 CTRI Data analysis determine Diabetes Mellitus dissemination dose Efficacy element eligibility assessment evaluate excluded exploratory Factor Fever filtered Herbal decoction hypertension IFNγ IL10 IL2 Immunity immunological independent India information investigator involved lactating malignancy management marker Medicine Microsoft Excel number objective Occurrence onset of symptom Open-label outcome parallel group participant positive pregnant Primary outcome progression protocol random number generation randomised randomised controlled trial randomization Randomized controlled trial receive recruit recruited recruitment reduced reducing reduction reduction in Registered reported RT-PCR Sample Sample size SARS-CoV-2 viral load sealed Secondary outcomes severe respiratory disease Siddha Siddha Medicine Standard state Study protocol submitted Symptom symptomatic Tablet tested the SARS-CoV-2 threshold TNF traditional methods Treatment Trial Tumor Vitamin website Zinc
[DOI] 10.1186/s13063-020-04823-z PMC 바로가기 [Article Type] Letter

Evaluation of the efficacy and safety of Melatonin in moderately ill patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial

중등도의 COVID-19 환자에서 멜라토닌의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-10-262022-08-13
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] 1:1 acute respiratory syndrome Adverse drug reaction Adverse drug reactions alcohol All study participants allergy allocation sequence Alpha anticipated Antiviral Arm ARMS assigned Bandar Abbas blinded Blinding block randomization Breastfeeding C-reactive protein Chain Reaction chronic hepatitis cirrhosis clinical clinical symptom Clinical symptoms clinical trials Clinicians Computed tomography conducted Confirmed Control control group Corticosteroids COVID-19 COVID-19 pneumonia criteria Critical Department Depression diabetes Diabetes Mellitus Diagnosis Diseases dissemination dose double-blind drug drugs education Efficacy and safety element evaluate exclusion criteria faculty feature generate Hepatitis history Hospitalization Hospitalized hypertension IL-1β IL-6 ill patient IMPROVE incidence inclusion criteria inflammatory parameter inflammatory parameters Inflammatory responses Informed consent interleukin interleukin-1β Iran liver diseases Medical Sciences Medicines melatonin Ministry of Health number Nurses objective outcome oxygen oxygen saturation parallel-group participant Participants Patient patients patients randomized pharmaceutical Pharmacy Placebo placebo-controlled clinical trial Pneumonia polymerase chain polymerase chain reaction polymerase chain reaction) positive Pregnancy Primary outcome Primary outcomes protocol random randomization Randomized Randomized controlled trial regimen Registered registration date registration number registry Research respiratory Sample size SARS-CoV-2 screened secondary outcome Secondary outcomes Seizure serum Seven Severe acute respiratory syndrome single-center standard treatment status Study protocol the Faculty therapeutic treatment arm trial protocol Trial registration Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-alpha two group two groups underlying diseases university Version Warfarin web-based system website X-ray
[DOI] 10.1186/s13063-020-04737-w PMC 바로가기 [Article Type] Letter

Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial

COVID-19 전염병 동안 의료 종사자를 위해 개발된 온라인 인지 행동 치료 프로그램의 효능: 무작위 대조 시험을 위한 STress 감소(REST) 연구 프로토콜

Study Protocol

Published on 2020-10-212022-08-13
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] ‘My Health too’ CBT program acceptability Accessibility active control group active treatment assessment assessments behavioral therapy bibliotherapy CBT CBT program Chinese circumvent Clinical practice cognitive cognitive behavioral therapy consequence COVID-19 COVID-19 epidemic COVID-19 pandemic credibility decrease Depression effective Efficacy epidemic peak evaluate evidence-based psychological treatment evidence-based psychological treatments expected facilitate flexibility Follow-up Health Health crisis healthcare Healthcare systems healthcare worker Healthcare workers healthcare workers’ mental health immediate perceived stress immediate stress include Insomnia Internet-Based Intervention internet-based interventions long-lasting management mental health mental health toll Online CBT online CBT program open open trial outcome pandemic status Perceived Stress Scale Population Post-traumatic stress disorder prevalence rate prevalence rates Primary outcome Program PSS-10 PSS-10 score PSS-10 scores psychiatric disorder Psychiatric disorders psychological disorder psychological disorders Psychological distress PTSD random assignment Randomized controlled trial Registered reported required Resilience REST Rumination Satisfaction secondary Secondary outcomes significantly sleep disorders Stress stress level stress levels stress-related disorder stress-related disorders Study protocol systemic impact the disease the epidemic therapy Treatment Trial registration
[DOI] 10.1186/s13063-020-04772-7 PMC 바로가기 [Article Type] Study Protocol

Redefining the Prognostic Value of High-Sensitivity Troponin in COVID-19 Patients: The Importance of Concomitant Coronary Artery Disease

Article

Published on 2020-10-122022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

Thromboprophylaxis with enoxaparin is associated with a lower death rate in patients hospitalized with SARS-CoV-2 infection. A cohort study

Research paper

Published on 2020-10-052022-10-31
Journal: EClinicalMedicine [Category] COVID-19,

[키워드] Adjusted analysis Admission analyzed caused Cohort cohort study collected coronavirus Coronavirus disease 2019 COVID-19 death rate Effect Endothelial cell enoxaparin evaluated Evidence finding foundation heparin hospital Hospital stay Hospitalization hypercoagulability in-hospital mortality Infection intensive care intensive care unit Invasion Logistic regression low molecular weight heparin Mortality multivariate nine overlap weight Patient patients hospitalized patients treated Poisson regression polymerase chain positive Proinflammatory cytokine randomized clinical trial Rate Ratio real time reduce reduced risk respiratory reverse transcription risk RT-PCR SARS-CoV-2 SARS-COV-2 infection Secondary outcomes Support Thromboprophylaxis Treatment was used
[DOI] 10.1016/j.eclinm.2020.100562 PMC 바로가기 [Article Type] Research paper