A Novel Bayesian Optimization-Based Machine Learning Framework for COVID-19 Detection From Inpatient Facility DataComputers and information processing Published on 2021-01-112022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] ADASYN Algorithm Analysis applied approach Bayesian Bayesian optimization build can be used classification Classifier clinically COVID COVID patient COVID-19 COVID-19 patient dataset demonstrated detection Efficacy Efficiency facility feature framework Gradient highest Inpatient inpatient's facility data less machine learning nine novel operable pandemic problems provide random required Support transmitted virus [DOI] 10.1109/ACCESS.2021.3050852 PMC 바로가기 [Article Type] Computers and information processing
Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse LungImmunology Published on 2021-01-082022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] ACE2 ACE2 sequence acute lung injury Analysis analyzed approaches Bayesian Body weight loss BXD family caused chromosome core Coronaviruses defined disease disease risk disease severity Dissection enzyme epithelial cells expression expression level function gene co-expression network gene product H1N1 Hierarchical Host host response identify include Infection Influenza influenza A virus lung Lung infection Lung injury MAPK membrane-bound MERS-CoV mice modulate molecular morbidity and mortality mouse mRNA level network analysis outcome parental participated potential therapeutic target primary human airway Protein pulmonary quantified respiratory diseases RNA-Seq SARS-CoV SARS-CoV-2 Sepsis severity signaling pathways significantly strain TNF transcript Transcriptome variant viral infection viral infections Viral load viremia network weight loss WGCNA [DOI] 10.3389/fimmu.2020.607314 PMC 바로가기 [Article Type] Immunology
Transmission route and introduction of pandemic SARS-CoV-2 between China, Italy, and Spain중국, 이탈리아, 스페인 간 전염병 SARS-CoV-2의 전파 경로 및 도입Article Published on 2021-01-012022-09-11 Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis assumption Bayesian China circulation classical CLOCK coronavirus country Decision-making epidemiological epidemiological surveillance event events Evolution explain Frame genome sequence GISAID highest Italy median Migration migration rate molecular multitype bearth-death number of introductions. occurred pandemic phylodynamic phylogeographic analysis proportion public health respiratory SARS-CoV-2 Shanghai Spain Surveillance TMRCA tree virus while [DOI] 10.1002/jmv.26333 PMC 바로가기 [Article Type] Article
Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical TrialCOVID-19 및 중등도 또는 중증 폐렴으로 입원한 성인에서 Tocilizumab 대 일반 치료의 효과: 무작위 임상 시험Randomized Controlled Trial Published on 2021-01-012022-09-11 Journal: JAMA Internal Medicine [Category] 임상, 진단, 치료제, [키워드] 95% CI adjusted Admission adverse event adverse events age Analysis antibiotic Anticoagulants Antiviral agents ARD assigned Bayesian C-reactive protein Care clinical clinical status clinical trial clinically conducted Consent coronavirus disease Coronavirus disease 2019 Corticosteroids COVID-19 COVID-19 pneumonia credible interval CrI death determine did not reduce died discharge Effect Efficacy elevated Factor Fewer patients Follow-up France greater hazard ratio Health Organization hyperinflammation Identifier IMPROVE indicated intensive care intensive care unit intention-to-treat basis interleukin-6 interquartile range intravenously investigator-initiated less mechanical ventilation median moderate moderate-to-severe COVID-19 pneumonia Mortality multicenter multiplicity NIV no difference Noninvasive ventilation occurred Open-label outcome overall survival oxygen oxygen supply oxygen support Patient patients patients hospitalized patients with COVID-19 performed Pneumonia posterior probability Primary outcomes randomized clinical trial Randomly receive recruited reduced risk risk difference scale secondary Secondary outcomes Serious Adverse Events severe pneumonia survival TCZ threshold Tocilizumab treat university hospital usual care usual care alone vasopressor support Ventilation WHO-CPS women World Health Organization [DOI] 10.1001/jamainternmed.2020.6820 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 risk in elective surgery during a second wave: a prospective cohort studyObservational Study Published on 2021-01-012022-10-04 Journal: ANZ journal of surgery [Category] 임상, [키워드] affected anaesthesia Asymptomatic Bayesian children cohort study conducted coronavirus COVID-19 COVID-19 pandemic determine eight Elective surgery enrolled healthcare healthcare worker hospital incidence Infection likelihood negative test outcome Patient patients PCR polymerase chain positive positive PCR test Prevalence Primary outcome Probability Prospective prospective cohort study public health questionnaire resulting risk SARS-CoV-2 screened second wave study period surgery surgical Surveillance Transmission Victoria [DOI] 10.1111/ans.16464 PMC 바로가기 [Article Type] Observational Study
No credible evidence for links between 2D:4D and COVID-19 outcomes: A probabilistic perspective on digit ratio, ACE variants, and national case fatalities2D:4D와 COVID-19 결과 사이의 연관성에 대한 신뢰할 수 있는 증거 없음: 숫자 비율, ACE 변종 및 전국 사례 사망률에 대한 확률론적 관점Article Published on 2021-01-012022-09-11 Journal: Early human development [Category] 변종, [키워드] 2D:4D absence ACE ACE1 ACE2 allele androgen angiotensin Angiotensin-converting enzyme article articles association Bayesian Bayesian analysis Bayesian inference COVID-19 COVID-19 mortality COVID-19 susceptibility Critical described digit ratio Digit ratio. evaluated Evidence evidence of fatality female frequencies Frequency Genotype Grounding Hypothesis male National offer outcome outcomes Perspective prenatal Prevalence prognostic robust second wave statistical statistical inference suggested utility variant variants [DOI] 10.1016/j.earlhumdev.2020.105272 PMC 바로가기 [Article Type] Article
Indirect effects of the COVID-19 pandemic on malaria intervention coverage, morbidity, and mortality in Africa: a geospatial modelling analysis아프리카의 말라리아 개입 범위, 이환율 및 사망률에 대한 COVID-19 전염병의 간접적 영향: 지리공간 모델링 분석Articles Published on 2021-01-012022-10-29 Journal: The Lancet. Infectious Diseases [Category] COVID-19, Fulltext, SARS, 말라리아, [키워드] absence Affect African Analysis anticipated antimalarial baseline Bayesian channel country Coverage COVID-19 COVID-19 pandemic database death distribution Effect effective estimate evaluate finding funding greater hypothetical incidence increases in Intervention malaria malaria control Melinda Gate morbidity Mortality nine predicted public health reduced reducing reduction reduction in reductions in repeated spatiotemporal subsequent Telethon Treatment Trust [DOI] 10.1016/S1473-3099(20)30700-3 PMC 바로가기 [Article Type] Articles
Superspreading in early transmissions of COVID-19 in IndonesiaArticle Published on 2020-12-282022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] basic reproduction number Bayesian can be used collected confirmed case COVID-19 COVID-19 transmission Critical determine Diagnosis Diseases distribution early stage effective epidemiological Health care heterogeneity individual Indonesia Isolation Measures Negative binomial distribution number of infected outbreak parameter Region regions responsible secondary case secondary infections superspreading event superspreading events Transmission Variation [DOI] 10.1038/s41598-020-79352-5 PMC 바로가기 [Article Type] Article
Updated confidence intervals for the COVID-19 antibody retention rate in the Korean populationResearch Communication Published on 2020-12-242022-11-01 Journal: Genomics & Informatics [Category] COVID-19, [키워드] 95% confidence interval antibody formation Antibody titer asymptotic Bayesian confidence interval Confidence intervals coronavirus disease country COVID-19 COVID-19 antibody General population globe hidden identify immune individual Infection Korean male management pandemic point estimate positive quarantine reported retention rate serology test South Korea Spread standard error statistical Wald method were infected Youth [DOI] 10.5808/GI.2020.18.4.e45 PMC 바로가기 [Article Type] Research Communication
Public Health Interventions’ Effect on Hospital Use in Patients With COVID-19: Comparative StudyObservational Study Published on 2020-12-232022-10-04 Journal: JMIR Public Health and Surveillance [Category] MERS, 임상, [키워드] association Bayesian China Clinical stage Comparative COVID-19 COVID-19 pandemic cured data-driven death case declined Effect effective estimated rate evaluated Evidence Face mask functions hospital Hospitalized implementation IMPROVE incidence indicate Infection intensive care Intervention Mask New York objective Observational pandemic Patient prediction Prevent provided Public public health Public health intervention quarantine reduced reducing Reproduction number required Result significantly social distancing state stratified susceptible the disease the United State transmission rate United States use wearing wearing mask [DOI] 10.2196/25174 PMC 바로가기 [Article Type] Observational Study