Antiviral drugs for varicella-zoster virus and herpes simplex virus infectionsReview Published on 2018-09-242023-06-01 Journal: The Medical letter on drugs and therapeutics [Category] 두창, 수두, 홍역, [키워드] Abreva acyclovir adverse effects Cidofovir Denavir docosanol dosage Efficacy famciclovir Famvir Foscarnet Ganciclovir herpes simplex virus HSV imiquimod IVIG Penciclovir Pregnancy Safety trifluridine Vaccines valacyclovir Valtrex Varicella zoster virus Varizig Viroptic VZV Zirgan Zovirax Zyclara [Article Type] Review
Antibody Kinetics and Response to Routine Vaccinations in Infants Born to Women Who Received an Investigational Trivalent Group B Streptococcus Polysaccharide CRM 197 -Conjugate Vaccine During Pregnancy조사 3가 그룹 B 연쇄상구균 다당류 CRM 197 -임신 중 접합 백신을 받은 여성에게서 태어난 영아의 항체 동역학 및 정기 예방 접종에 대한 반응Articles and Commentaries Published on 2017-12-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, 백일해, 파상풍, [키워드] age antenatal vaccination antibody antibody level antibody levels Birth capsular clinical clinically Combination detectable Diphtheria diphtheria toxoid disease dosage dosages dose during pregnancy elicited enrolled geometric mean geometric mean concentration group group B Streptococcus conjugate vaccine groups Haemophilus influenzae Haemophilus influenzae type b immune response immune responses Infant Infants invasive investigated Kinetics Maternal mother not affect pediatric Placebo placebo group pneumococcal pneumococcal vaccination Pregnancy Randomized receive Received recipients Registration response Result routine routine immunization serotype serotype-specific serotypes significantly higher single-center study Streptococcus Tetanus the placebo group timepoint transferred trivalent vaccination Vaccine were assessed women [DOI] 10.1093/cid/cix666 PMC 바로가기 [Article Type] Articles and Commentaries
A dominant-negative mutant inhibits multiple prion variants through a common mechanism우성-음성 돌연변이는 공통 메커니즘을 통해 여러 프리온 변이체를 억제합니다Research Article Published on 2017-10-302022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] amyloid cells chaperone chaperones clearance conformation conformational conformations curing daughter cells determine determined by disorders dominant-negative dosage doses Effect fiber human disease inhibit inhibited inhibitor inhibitors interfere Intervention kinetic Lower mechanism mode molecular mutant observation overcome pathway persistence phenotype Phenotypes plasticity prion Protein protein conformations reported resulting sensitivity shown specificity stability unique variant variants [DOI] 10.1371/journal.pgen.1007085 PMC 바로가기 [Article Type] Research Article
Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cellsB 세포 발달 동안 비활성 X에서 Xist RNA의 손실은 활성화된 B 세포에서 동적 YY1 종속 2단계 과정으로 복원됩니다.Research Article Published on 2017-10-092022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activated Activation adulthood Autoimmune disorders Autoimmunity B cell B cells Cell change chromatin chromosome compensated Critical develop DNA DNA binding domain dosage ectopic expression embryogenesis Epigenetic Ex vivo expression female Genes Genetic heterochromatin Immunity impair inactivation inactive indicate lack Lineage Loss lymphocyte Lymphocytes mechanism Modification modifications pathogenic pattern Recombination regulate regulated restored reveal RNA Stimulation susceptibility transcription factor up-regulation X-linked X-linked gene YY1 Zinc [DOI] 10.1371/journal.pgen.1007050 PMC 바로가기 [Article Type] Research Article
SARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J MiceArticle Published on 2016-06-282022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] acute respiratory syndrome antiviral immune response approach Arthritis Autoimmune cartilage chain coronavirus disease dosage Efficacy evade Evidence fusion fusion peptide Host Host immune response hosts Hypothesis immune immunomodulatory in vivo include incorporation increase Infection involved lipoprotein mice modulate molecular mechanism multichain peptide PROTECT receptor replicate SARS-CoV sequence Signaling significantly suggested Support T cell receptor target TCR therapeutic strategy transferred Viral immune evasion virus [DOI] 10.1038/srep28672 PMC 바로가기 [Article Type] Article
Single-dose administration of inactivated hepatitis A vaccination in the context of hepatitis A vaccine recommendationsReview Published on 2013-11-012023-05-31 Journal: International Journal of Infectious Diseases [Category] A형 간염, [키워드] booster dosage hepatitis A virus Inactivated vaccine [DOI] 10.1016/j.ijid.2013.04.012 [Article Type] Review
Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS VirusResearch Article Published on 2012-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] acute respiratory syndrome antibody C57BL/6 candidate vaccine caution challenge change changes in China component control group country dosage eosinophil evaluated exhibited ferret Histopathology Human hypersensitivity immunopathology inactivated indicated Infection infiltration Influenza initiated led to Live virus lung Lung disease mice NHP occurred Occurrence pathologic PBS pulmonary responses Result S protein SARS Coronavirus SARS-CoV SARS-CoV vaccine serum antibody Serum neutralizing antibody severe Significant reduction significantly spread to Th2-type the vaccine Vaccine Vaccine development virus VLP [DOI] 10.1371/journal.pone.0035421 PMC 바로가기 [Article Type] Research Article
SARS: Systematic Review of Treatment EffectsResearch Article Published on 2006-09-122022-10-29 Journal: PLoS Medicine [Category] Coronavirus, [키워드] 2003 active against acute respiratory distress acute respiratory syndrome adverse effect affected antiviral drug ARDS Author be applied Blood carried caused CENTRAL China clinical clinical trial clinician conducted Controlled convalescent plasma Corticosteroids cough criteria Culture database death death rate determine disease dosage drug Effect effective Effectiveness Evidence example Fever finding found group had no Health care help helping HIV/AIDS identify IFN IFN type I immune system immunoglobulins In vitro studies in vitro study include inclusion criteria Inconclusive Inflammation information Intravenous immunoglobulin Laboratory life-threatening Lungs MedlinePlus MONITOR NO occurred outbreak Outbreaks Patient patients patients with SARS Pneumonia Potential treatment Protein protocol real time recommendation reduce reduced reported Research researcher review ribavirin Ritonavir SARS patients SARS-CoV SARS-infected patient SARS-infected patients searched severe sneeze Source specific symptom steroid Steroids Symptom syndrome systematic review the WHO tissue treat Treatment Trial Type I IFN type I interferon viral disease virus viruses Web while WHO Wikipedia World Health Organization [DOI] 10.1371/journal.pmed.0030343 PMC 바로가기 [Article Type] Research Article