The Structural Biology of Hepatitis B Virus: Form and FunctionReview Published on 2016-09-292023-06-18 Journal: Annual Review of Virology [Category] B형 간염, Fulltext, [키워드] Antiviral capsid icosahedral nucleoprotein complex reverse transcriptase Self-Assembly. [DOI] 10.1146/annurev-virology-110615-042238 PMC 바로가기 [Article Type] Review
Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents, and young adults (BREATHER): a randomised, open-label, non-inferiority, phase 2/3 trialHIV에 감염된 어린이, 청소년 및 젊은 성인(BREATHER)에 대한 주말 휴무 에파비렌즈 기반 항레트로바이러스 요법: 무작위, 공개, 비열등성, 2/3상 시험Articles Published on 2016-06-202022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 1:1 abortion adherent adverse event African age Antiretroviral therapy ART assigned block BREATHER CD4 cell Cell children clinician computer-generated country CTA Dizziness drug efavirenz eligible participant Eligible participants EudraCT European European Commission event finding FIVE France funding grade 3 gynaecomastia headache HIV-1 ideation inferiority inhibitors Intention intention to treat IQR ISRCTN Kaplan-Meier method less life Lipodystrophy list median median age Medical Research Council men neutropenia non-inferiority non-inferiority margin non-inferiority trial nucleoside occurred offer Open-label participant Patient phase 2/3 trial Primary outcome proportion raised randomisation randomisation list randomised Randomly reached Registered reverse transcriptase RNA safety profile Seven shown spontaneous abortion stratified Suicidal ideation Syncope technology Technology assessment the Kaplan-Meier method therapy Toxicity transaminases transcriptase Trial Viral Viral load virological suppression was done web service [DOI] 10.1016/S2352-3018(16)30054-6 PMC 바로가기 [Article Type] Articles
Higher detection rates of amino acid substitutions in HBV reverse transcriptase/surface protein overlapping sequence is correlated with lower serum HBV DNA and HBsAg levels in HBeAg-positive chronic hepatitis B patients with subgenotype B2Article Published on 2016-06-012023-06-19 Journal: Infection, genetics and evolution : journal of mol [Category] B형 간염, [키워드] Hepatitis B virus reverse transcriptase Subgenotype B2 Substitution Surface protein. [DOI] 10.1016/j.meegid.2016.03.019 PMC 바로가기
Mutations in the S gene and in the overlapping reverse transcriptase region in chronic hepatitis B Chinese patients with coexistence of HBsAg and anti-HBsArticle Published on 2016-01-012023-06-19 Journal: The Brazilian journal of infectious diseases : an [Category] B형 간염, [키워드] Chronic Hepatitis B coexistence of HBsAg and anti-HBs reverse transcriptase S gene. [DOI] 10.1016/j.bjid.2015.08.014 PMC 바로가기
SWIFT: Prospective 48-Week Study to Evaluate Efficacy and Safety of Switching to Emtricitabine/Tenofovir From Lamivudine/Abacavir in Virologically Suppressed HIV-1 Infected Patients on a Boosted Protease Inhibitor Containing Antiretroviral RegimenSWIFT: 항레트로바이러스 요법을 포함하는 강화된 프로테아제 억제제를 사용하는 바이러스학적으로 억제된 HIV-1 감염 환자에서 라미부딘/아바카비르에서 엠트리시타빈/테노포비어로 전환하는 것의 효능 및 안전성을 평가하기 위한 전향적 48주 연구HIV/AIDS Published on 2013-06-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, [키워드] 3TC/ABC 95% confidence interval abacavir addition Arm ARMS backbone baseline characteristics calculated CD4 Characteristics cholesterol compared Containing Decline decrease Decreased defined Efficacy and safety EGFR emtricitabine emtricitabine/tenofovir epidermal epidermal growth factor evaluate FTC/TDF fumarate GFR greater growth factor HIV patient HIV patients HIV-1 Human immunodeficiency virus immunodeficiency virus improvement Improvements Infected inhibitor lamivudine LDL Lipid lipids Lipoproteins Low-density lipoprotein low-density lipoproteins male median median age nucleoside Open-label parameter Patient PI primary endpoint Prospective Protease inhibitor Randomized rebound receiving receptor regimen reverse transcriptase risk score Ritonavir RNA RTV Safety study drug subject suppressed switch switching tenofovir disoproxil fumarate TG The United States threshold Total cholesterol transcriptase treated treatment difference Triglyceride triglycerides United States virologic failure Virologic suppression [DOI] 10.1093/cid/cis1203 PMC 바로가기 [Article Type] HIV/AIDS
Using patient-collected clinical samples and sera to detect and quantify the severe acute respiratory syndrome coronavirus (SARS-CoV)Research Published on 2007-03-272022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome Beijing caused China clinical sample collected coronavirus detect detected detection rate Fecal sample highest hospital resources laboratory confirmation laboratory-confirmed log nasopharyngeal aspirate onset of symptoms outbreak Patient Pneumonia polymerase chain positive Result reverse transcriptase RT-PCR SARS-CoV SARS-CoV infection sera severe Viral load was used [DOI] 10.1186/1743-422X-4-32 PMC 바로가기 [Article Type] Research