Role of diagnostic imaging technologists during the COVID-19 pandemic: The importance of organization and planning in the first lineResearch article Published on 2021-01-012022-10-05 Journal: Radiología [Category] 진단, [키워드] adopted Care change COVID-19 COVID-19 pandemic creating defined diagnosis of COVID-19 diagnostic health system measure organization outbreak pandemic patients with COVID-19 Planning Prevision Protective protocol provide radiology recommendation required resource role [DOI] 10.1016/j.rxeng.2020.09.010 [Article Type] Research article
Effectiveness of COVID-19 shelter-in-place orders varied by stateObservational Study Published on 2020-12-312022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] approach black COVID-19 creating dataset Donald Effect effective Google Impact pandemic reduced reduction spread of COVID-19 state stratified Study design unlikely [DOI] 10.1371/journal.pone.0245008 PMC 바로가기 [Article Type] Observational Study
Interactive Molecular Dynamics in Virtual Reality Is an Effective Tool for Flexible Substrate and Inhibitor Docking to the SARS-CoV-2 Main Protease가상 현실의 대화형 분자 역학은 SARS-CoV-2 메인 프로테아제에 대한 유연한 기질 및 억제제 도킹을 위한 효과적인 도구입니다Article Published on 2020-12-282022-09-11 Journal: Journal of Chemical Information and Modeling [Category] SARS, 변종, 신약개발, 치료제, [키워드] approach backbone binding interactions build Community complexes COVID-19 creating crystal structure crystal structures crystallographic structure demonstrated docked docking Drug development Dynamics effective effort enzyme flexibility flexible focus hydrogen hydrogen bonds inhibitor MD simulation MD simulations Metrics molecular molecular dynamics MPro oligopeptide open physically PLOS protease Protein protein complex protein complexes Protein target protocol provide REALITY recommendation Research RMSD SARS-CoV-2 virus small molecule small molecule drug small molecule drugs software framework Structure structures substrate targets tested the SARS-CoV-2 the SARS-CoV-2 virus user Viral virtual reality [DOI] 10.1021/acs.jcim.0c01030 PMC 바로가기 [Article Type] Article
The Need for Antiviral Drugs for Pandemic Coronaviruses From a Global Health PerspectiveMedicine Published on 2020-12-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Administered Antiviral antiviral drugs antiviral therapy caused clinical study clinical trial conserved coronavirus Coronaviruses COVID-19 COVID-19 pandemic creating Dexamethasone disease stage drug Drug discovery drugs early treatment effective global health hospital hospitalized patients Infection influenza viruses Interaction investigated majority Mortality outbreak preparedness pandemic pharmacotherapy Prevent recovery Remdesivir respiratory respiratory viral infection respiratory virus SARS-CoV-2 solidarity Stage symptom duration target product profile the disease the United State Treatment viral dynamics Viral load Viral pneumonia Viral protein widespread [DOI] 10.3389/fmed.2020.596587 PMC 바로가기 [Article Type] Medicine
Post-Acute COVID-19 Rehabilitation Network Proposal: From Intensive to Extensive and Home-Based IT Supported ServicesArticle Published on 2020-12-142022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] addition analyzed approach Care clinical activity clinical governance Clinical management clinician coding continuum COVID-19 COVID-19 emergency creating database effective Effectiveness Efficacy Efficiency Europe European Extensive feasibility Health healthcare Healthcare system Healthcare systems ICF Infection information International IT Italian Italy management National network network model Patient patients platform positive post COVID-19 care post-acute rehabilitation post-COVID-19 patient rehabilitation resource resources respond Satisfaction service Spread SWOT analysis syndrome the patient Treatment [DOI] 10.3390/ijerph17249335 PMC 바로가기 [Article Type] Article
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies Reviews Published on 2020-12-142022-10-05 Journal: Nature reviews. Neurology [Category] 바이오마커, [키워드] Brain caused cognitive covert creating Diagnosis disorder Evidence functional IMPROVE Injury intensive care mechanism mechanisms Patient pharmacological predict preserved Prognosis promote question raising review shown stages therapy [DOI] 10.1038/s41582-020-00428-x [Article Type] Reviews
Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs다중 팔 PEG 나노바디 구조를 사용한 피코몰 SARS-CoV-2 중화Article Published on 2020-12-112022-09-01 Journal: Biomolecules [Category] MERS, SARS, 변종, 진단, [키워드] alkyne approach azide C-terminus click chemistry component components creating demonstrated functional functional groups fusion glycol group Infectious virus ligation multivalent Multivalent antibody nanobodies nanobody neutralization neutralization assays neutralize neutralized Neutralizing PEG linker Polyethylene glycol promoted SARS-CoV-2 SARS-CoV-2 pseudotyped virus single-domain antibody fragment small molecule sortase A terminal the SARS-CoV-2 variant viability virus [DOI] 10.3390/biom10121661 PMC 바로가기 [Article Type] Article
Druggability for COVID-19: in silico discovery of potential drug compounds against nucleocapsid (N) protein of SARS-CoV-2Original Article Published on 2020-12-092022-11-01 Journal: Genomics & Informatics [Category] COVID-19, [키워드] acute respiratory syndrome analyzed antiviral drug approaches binding affinities binding affinity binding domain caused Compound conserved contagious coronavirus coronavirus disease COVID-19 creating Critical disease domain drug drug target druggability function Good Hydrogen bond identify in silico molecular docking Molecular modeling morbidity Mortality N protein nucleocapsid nucleocapsid protein offer Phylogenetic relationship Protein Region researcher RNA SARS-CoV-2 SARS-COV-2 infection selected sequence the SARS-CoV-2 these compounds Treatment Vaccine Vaccine development viral life cycle viral replication virus widespread [DOI] 10.5808/GI.2020.18.4.e43 PMC 바로가기 [Article Type] Original Article
Health behaviours during the coronavirus disease 2019 pandemic: implications for obesityCommentary Published on 2020-12-042022-10-29 Journal: Public Health Nutrition [Category] Coronavirus, MERS, SARS, [키워드] Alter approach assist cardiometabolic Care change Chronic diseases Community coronavirus disease Coronavirus disease 2019 COVID-19 creating death diet Diseases effort exacerbating Health Health behaviours immune health implication individual individual level Inflammation influence Intervention long-lasting mitigate obesity pandemic physical activity populations Prevalence Prevent professional provided Public public health reduce risk factor severe complication [DOI] 10.1017/S1368980020003031 PMC 바로가기 [Article Type] Commentary
Unscreened: Urgent and Emergent Surgical Outcomes in the Early COVID-19 PandemicGeneral Surgery Published on 2020-12-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Analysis changes in Characteristics characteristics of patient Clinical outcome coronavirus coronavirus disease COVID-19 COVID-19 testing creating criteria early stage emergent surgeries evaluate group ICU include intensive care invasive ventilation lack mortality rate pandemic Patient patients positive protocol recommendation resource Result retrospective SARS-CoV-2 SARS-CoV-2 pandemic surgical Surgical Procedure symptomatic Symptoms tested Testing the patient the SARS-CoV-2 The United States urgent surgeries was performed [DOI] 10.7759/cureus.11878 PMC 바로가기 [Article Type] General Surgery