SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodiesSARS-CoV-2 Omicron 하위 계통은 유사한 세포 진입을 나타내지만 치료 항체에 의한 차등 중화를 나타냅니다.Article Published on 2022-08-102022-09-11 Journal: Cell Host & Microbe [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] ACE2 antibodies antibody Antibody-mediated neutralization BNT162b2 booster vaccination cell entry cilgavimab comparable COVID-19 COVID-19 therapy Efficiency eight evade exhibit FUSE homologous or heterologous neutralization neutralized omicron Omicron variant SARS-CoV-2 Seven Sotrovimab spike susceptibility target cell target cells therapeutic therapeutic antibodies therapy Transmissibility Treatment vaccination Vaccine vaccine-induced antibodies vaccine-induced antibody variant of SARS-CoV-2 [DOI] 10.1016/j.chom.2022.04.017 PMC 바로가기 [Article Type] Article
Inactivated vaccine Covaxin/BBV152: A systematic review비활성화 백신 Covaxin/BBV152: 체계적인 검토Article Published on 2022-08-092022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, [키워드] adjusted Administered adverse event Aluminium aluminium hydroxide Antigen AZD1222 BBV152 Beta Bharat binding antibody clinical trial Combination Corona Covaxin Coverage Covishield Delta Delta variants doses Effectiveness Efficacy Evidence evidence of fatality gel heterologous prime-boost hydroxide immunogenicity inactivated Inactivated vaccine India infected individual Local Neutralizing omicron Omicron variant pandemic phase Phase I Phase III trials provided Quinolin reported Safety safety profile SARS-CoV-2 pandemic screened searched second dose Serious Adverse Event Serious Adverse Events severe COVID-19 surpassed symptomatic infection systematic review systemic adverse events T cell T cell response T cell responses the SARS-CoV-2 Trial vaccination Vaccine Vaccines variant variants virus Zeneca [DOI] 10.3389/fimmu.2022.863162 PMC 바로가기 [Article Type] Article
Targeting the Receptor-Binding Motif of SARS-CoV-2 with D-Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of ConcernACE2 결합 나선을 모방한 D-펩타이드로 SARS-CoV-2의 수용체 결합 모티프 표적화: 오미크론 및 우려되는 미래 변이를 억제하기 위한 교훈Article Published on 2022-08-082022-09-11 Journal: Journal of Chemical Information and Modeling [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 binding Alpha approach B.1.1.529 Beta binding blocked concern COVID-19 pandemic demonstrated domain Future high-affinity binding IC50 IC50s in vitro In vitro infection Infection inhibiting inhibitor lesson motif Mutation neutralizing monoclonal antibodies omicron Omicron variant overlapping predicted public interest RBD receptor-binding motif SARS-CoV-2 Spike protein Spread targeting the RBD the spike protein variant VoC VOCs [DOI] 10.1021/acs.jcim.2c00500 PMC 바로가기 [Article Type] Article
Outbreak caused by the SARS-CoV-2 Omicron variant in the psychiatric ward of a general hospital in Brazil브라질 종합병원 정신병동에서 SARS-CoV-2 오미크론 변종으로 인한 발병Article Published on 2022-08-052022-09-11 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 applied attack rate Brasília Brazil caused clinical outcomes Comorbidities coronavirus General Hospital generate highlight hospital Hospitalized intensive care measure omicron Omicron variant outbreak populations Psychiatric required SARS-CoV-2 sequenced samples Sequencing severe acute respiratory syndrome Coronavirus the SARS-CoV-2 those with comorbidities transmissible variant variant [DOI] 10.1590/0037-8682-0177-2022 PMC 바로가기 [Article Type] Article
Interferon α-2b spray shortened viral shedding time of SARS-CoV-2 Omicron variant: An open prospective cohort study인터페론 α-2b 스프레이는 SARS-CoV-2 오미크론 변이체의 바이러스 배출 시간을 단축: 공개 전향 코호트 연구Article Published on 2022-08-052022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 치료제, [키워드] 95% CI administration adverse effect against SARS-CoV Analysis antiviral activity China Cohort cohort study control group COVID-19 Effect Effectiveness enrolled examined experimental group first positive IFN IFN α IFN α-2b spray interferon less omicron Omicron variant participant Patient prospective cohort study protective effect protective factor SARS-CoV-2 SARS-CoV-2 Omicron variant SARS-CoV-2 variant Shanghai shown significantly spray Spread subgroup analysis the median treatment effect treatment effects univariate Cox regression univariate Cox regression analysis Vaccine viral shedding viral shedding time virus clearance virus transmission [DOI] 10.3389/fimmu.2022.967716 PMC 바로가기 [Article Type] Article
Association between COVID-19 and Sick Leave for Healthcare Workers in a Large Academic Hospital in Southern Italy: An Observational StudyCOVID-19와 남부 이탈리아의 대규모 학술 병원 의료 종사자의 병가 사이의 연관성: 관찰 연구Observational Study Published on 2022-08-052022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 변종, 임상, [키워드] CAT score changed conducted Coverage COVID-19 decrease evaluate HCWs healthcare healthcare worker Healthcare workers increase in involved Italy management observational study omicron Omicron variant optimization pandemic Perception public health questionnaire Regulation SARS-CoV-2 shown sick sick leave significant difference significant differences South subject Symptom Symptoms university hospital vaccination variant worker [DOI] 10.3390/ijerph19159670 PMC 바로가기 [Article Type] Observational Study
Patients with CLL have a lower risk of death from COVID-19 in the Omicron eraCLL 환자는 오미크론 시대에 COVID-19로 인한 사망 위험이 더 낮습니다Article Published on 2022-08-042022-09-11 Journal: Blood [Category] SARS, 변종, [키워드] 30-Day mortality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age antiviral therapy chronic lymphocytic leukemia CLL Cohort cohort of patient Comorbidity Contact coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death declined described disease course dominance General population high mortality hospital Hospitalization hospitalizations Immunocompromised Immunocompromised patient Immunocompromised patients intensive care leukemia lower risk Lymphocytic leukemia omicron Omicron variant outcome Patient population-based cohort positive Previous studies previous study remained reported SARS-CoV-2 SARS-CoV-2 test severe acute respiratory syndrome Coronavirus shown significantly tested variant [DOI] 10.1182/blood.2022016147 PMC 바로가기 [Article Type] Article
Risk Factors for Slow Viral Decline in COVID-19 Patients during the 2022 Omicron Wave2022년 오미크론 파동 동안 COVID-19 환자의 느린 바이러스 감소에 대한 위험 요소Article Published on 2022-08-042022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] Adult patients age Analysis Chronic kidney disease conducted COVID-19 Ct value Decline declined delta variant determine Factor Geriatrics highest hospitalised hyperlipidaemia hypertension independent risk factor Isolation Kidney disease Kinetics knowledge lowest Multivariate analysis Older age omicron Omicron variant Patient PSO remained retrospective cohort study risk factor Risk factors SARS-CoV-2 SARS-CoV-2 viral SARS-CoV-2 viral shedding slow statistically significant termination the timing Univariate analysis vaccination variant Viral load viral shedding Wave [DOI] 10.3390/v14081714 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Omicron Variant Neutralization after Third Dose Vaccination in PLWHPLWH에서 3차 접종 후 SARS-CoV-2 오미크론 변이체 중화Article Published on 2022-08-032022-09-11 Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, 치료제, [키워드] AIDS CD4 CD4 count CD4 counts detectable dose elicited Evidence evidence of HCW HCWs healthcare worker Healthcare workers HIV/AIDS mRNA vaccine neutralization neutralization titers neutralizing antibody no evidence of omicron Omicron variant participant Participants PLWH proportion SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2 vaccine serum sample serum samples target population the mean the SARS-CoV-2 third dose vaccine. undetectable Vaccine variant [DOI] 10.3390/v14081710 PMC 바로가기 [Article Type] Article
Risk of covid-19 related deaths for SARS-CoV-2 omicron (B.1.1.529) compared with delta (B.1.617.2): retrospective cohort study델타(B.1.617.2)와 비교한 SARS-CoV-2 오미크론(B.1.1.529)의 코로나19 관련 사망 위험: 후향적 코호트 연구Comparative Study Published on 2022-08-022022-09-11 Journal: The BMJ [Category] Fulltext, SARS, 변종, [키워드] 95% confidence interval adjusted age analysed B.1.1.529 B.1.617.2 Birth cause cohort study Community Comorbidities Comorbidity confounders country death deaths delta variant Deprivation disability England Ethnicity evidence of hazard ratio Hospital admission index Infection investigated main outcome measure National NHS no evidence of number of comorbidities omicron Omicron variant outcome PCR positive positive reduction in Regression model Research retrospective cohort study risk SARS-CoV-2 SARS-CoV-2 variant Severity of infection Sex Support Surveillance Test tested the SARS-CoV-2 trace United Kingdom vaccination Vaccination Status variant [DOI] 10.1136/bmj-2022-070695 PMC 바로가기 [Article Type] Comparative Study