Dehydrozingerone ameliorates Lipopolysaccharide induced acute respiratory distress syndrome by inhibiting cytokine storm, oxidative stress via modulating the MAPK/NF-κB pathwayDehydrozingerone은 MAPK/NF-κB 경로를 조절하여 사이토카인 폭풍, 산화 스트레스를 억제함으로써 지질다당류 유도 급성 호흡 곤란 증후군을 개선합니다Article Published on 2021-11-012022-09-11 Journal: Phytomedicine : international journal of phytother [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory distress acute respiratory distress syndrome alveolar alveolar inflammation analysed Analysis Apoptosis ARDS Bacterial BALF Cell cell damage cell injury cell lines chemokine chemokines country COVID-19 pandemic CRS cytokine Cytokine release syndrome Cytokine storm Cytokines Dehydrozingerone develop distress dose-dependent manner Elastase ELISA Endothelial cell endothelial cells evaluated event events Gene Expression Health Hyperactivation immune cells In-vitro increase in Infection Inflammation Inflammatory inflammatory cascade inflammatory cell inflammatory cells Inflammatory cytokine Inflammatory cytokines inhibiting Injury intensive care units lipopolysaccharide LPS lung cell lung epithelial Lung injury lung tissues macrophages majority MAPK MAPKinase marker modulating modulation molecular mechanism molecular mechanisms morbidity neutrophil NF-κB NF-κB pathways oxidative oxidative stress pathogen pathogen-mediated pathophysiology pathway performed Pneumonia problem Prophylactic protective effect Protective effects Protein provide RATs reduced respiratory distress resulting ROS significantly Standard therapy stimulate stimulated Support syndrome the patient therapeutic therapeutic activity therapeutic agent therapeutic effect therapeutic effects Treatment turn was determined western blot Western blot analysis [DOI] 10.1016/j.phymed.2021.153729 PMC 바로가기 [Article Type] Article
Thiol levels in mild or moderate COVID-19 patients: A comparison of variant and classic COVID-19 cases경증 또는 중등도 COVID-19 환자의 티올 수치: 변종 및 고전적인 COVID-19 사례 비교Article Published on 2021-11-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 변종, [키워드] added Analysis Blood blood count classic classical Clinical course complete blood count control group COVID-19 COVID-19 case COVID-19 cases COVID-19 diagnosis COVID-19 patient cross-sectional cross-sectional study cut-off value Diagnosis diagnosis of COVID-19 example ferritin groups healthy control hospital investigated lymphocyte marker Mild moderate Moderate COVID-19 neutrophil NLR oxidative stress parameter parameters Patient performed Predictive ROC analysis significantly significantly lower study group subject Symptom the study group thiol two group two groups variant venous venous blood was performed WBC [DOI] 10.1111/ijcp.14753 PMC 바로가기 [Article Type] Article
Changes in oxidative markers in COVID-19 patientsResearch article Published on 2021-11-012022-10-05 Journal: Archives of medical research [Category] SARS, 바이오마커, [키워드] affected albumin association benefit change controls COVID-19 COVID-19 patient CRP disease dismutase elevated ESR evaluated ferritin GPx groups human infectious disease ICU Inflammation Laboratory tests malondialdehyde marker MDA mechanism oxidative oxidative stress Pathogenesis Patient patients reducing Research Result serum Serum level significantly significantly higher significantly increased significantly lower Stress subjects the healthy Treatment were measured [DOI] 10.1016/j.arcmed.2021.06.004 [Article Type] Research article
Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approachCOVID-19에 대한 산화 스트레스 관계에 대한 검토: 생체 분자 및 생물 분석적 접근Review Published on 2021-10-312022-09-11 Journal: International journal of biological macromolecules [Category] SARS, 바이오마커, 치료기술, [키워드] addition affected antioxidant approach COVID-19 cure dependent on disease DNA effective enzyme Enzymes host immune system life life threatening mechanism of action Modern bioelectroanalytical techniques mutated oxidative stress oxygen pathway Protein Quantitative reactive oxygen specy review RNA ROS SARS-CoV-2 virus strength Stress the disease this system to define Vaccine virus [DOI] 10.1016/j.ijbiomac.2021.08.095 PMC 바로가기 [Article Type] Review
Zinc as a Drug for Wilson’s Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver InjuryReview Published on 2021-10-312022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] affected characterized coronavirus COVID-19 COVID-19 pandemic deficiency disorder drug drug therapy Effect Elderly patient enzyme gastrointestinal tract histological human physiology indicated Infection insulin resistance introduced Liver disease metabolism Mortality non-alcoholic liver disease oxidative stress Patient positive progression recorded reducing responsible risk SARS-CoV-2 severe disease similarities susceptibility Therapeutic approach therapy transcription factors Treatment undergo Wilson’s disease Wilson’s disease Zinc zinc supplementation [DOI] 10.3390/molecules26216614 PMC 바로가기 [Article Type] Review
Oxidative stress, malaria, sickle cell disease, and innate immunityarticle Published on 2021-10-312024-09-01 Journal: Trends in immunology [Category] 말라리아, [키워드] damage-associated molecular pattern high-mannose glycans malaria oxidative stress pathogen-associated molecular pattern phagocytosis Sickle cell disease [Article Type] article
Growth Differentiation Factor 15 (GDF-15): A Novel Biomarker Associated with Poorer Respiratory Function in COVID-19Brief Report Published on 2021-10-272022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] analysed Biomarker Biomarkers C-reactive protein circulating coronavirus disease correlated COVID-19 COVID-19 case D-dimer level differentiation Factor ferritin function GDF-15 healthy control Inflammation interleukin-6 laboratory parameter lymphopenia novel oxidative stress pathological condition Patient patients with COVID-19 pulmonary impairment receiver operating characteristics respiratory Respiratory function severity Stratification Support upregulated [DOI] 10.3390/diagnostics11111998 PMC 바로가기 [Article Type] Brief Report
Could Statin Therapy Be Useful in Patients With Coronavirus Disease 2019 (COVID-19)?Cardiovascular Medicine Published on 2021-10-272022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] abnormality acute respiratory disease syndrome Affect ARDS Arrhythmias Cardiomyopathy cardiovascular disorder Coagulation complications of COVID-19 coronavirus disease coronavirus disease (COVID-19) COVID-19 COVID-19 patient Critical death develop distress endothelial function enzyme Evidence exaggerated inflammatory response heart failure Inflammation modulate myocardial injury myocarditis oxidative stress Perspective pleiotropic receptor respiratory infection resulting severity statin statins syndrome thrombosis [DOI] 10.3389/fcvm.2021.775749 PMC 바로가기 [Article Type] Cardiovascular Medicine
A Unique Reverse Adaptation Mechanism Assists Bordetella pertussis in Resistance to Both Scarcity and Toxicity of Manganese독특한 역적응 메커니즘이 Bordetella pertussis의 망간 부족 및 독성 저항에 도움을 준다.Research Article Published on 2021-10-262024-08-01 Journal: mBio [Category] 백일해, [키워드] Bordetella Bordetella pertussis genome decay manganese oxidative stress pathogen adaptation [DOI] 10.1128/mBio.01902-21 PMC 바로가기 [Article Type] Research Article
Molecular Mechanisms of Multi-Organ Failure in COVID-19 and Potential of Stem Cell TherapyCOVID-19에서 다기관 실패의 분자 메커니즘과 줄기 세포 치료의 잠재력Review Published on 2021-10-252022-09-11 Journal: Cells [Category] MERS, SARS, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 blood-brain-barrier caused Cell therapy confirmed case confirmed cases coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients damage death failure Health major organ mesenchymal molecular mechanism molecular mechanisms multi-organ failure organ system organ systems oxidative stress Potential regenerative respiratory respiratory distress SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe respiratory distress STEM stem cell Stem cell therapy stem cells systemic damage Therapeutics treating COVID-19 [DOI] 10.3390/cells10112878 PMC 바로가기 [Article Type] Review