Frequent Infection of Cats With SARS-CoV-2 Irrespective of Pre-Existing Enzootic Coronavirus Immunity, Brazil 2020기존의 Enzootic 코로나 바이러스 면역과 관계없이 SARS-CoV-2에 고양이의 빈번한 감염, 브라질 2020Article Published on 2022-04-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% CI Affect affected Antibody titer Antibody titers B.1 Bovine coronavirus Brazil carnivore cats cats (felis catus) coronavirus COVID-19 cross-reactivity elicited Endemic ENhance Gamma homogeneous hot spot human immunity immune response immune responses Infection infection level investigated magnitude neutralization test Neutralizing antibody titer neutralizing antibody titers no significant difference pandemic plaque reduction neutralization Plaque reduction neutralization test pre-existing immunity prevents PRNT raise SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 mutation SARS-CoV-2 seroprevalence serology Seroprevalence serostatus Seven significant difference significantly higher significantly lower Spread susceptible Transmission variant zoonosis [DOI] 10.3389/fimmu.2022.857322 PMC 바로가기 [Article Type] Article
Effectiveness and Safety of Regdanvimab in Patients With Mild-To-Moderate COVID-19: A Retrospective Cohort Study경증에서 중등도의 COVID-19 환자에서 Regdanvimab의 효과 및 안전성: 후향적 코호트 연구Article Published on 2022-04-042022-09-12 Journal: Journal of Korean medical science [Category] 진단, [키워드] 1:1 95% CI 95% confidence interval Administered Adverse reaction Adverse reactions Analysis analyzed antibody center clinical recovery Cohort conducted coronavirus disease COVID-19 death disease Effect Effectiveness groups hematological high-flow oxygen therapy Hospital stay In-hospital death indicated information mechanical ventilation Mild Mild-to-moderate Moderate COVID-19 monoclonal need for oxygen Odds ratio outcome Oxygen therapy Patient patients patients treated phase 2/3 Primary outcome Randomized controlled trial reached reduced regdanvimab risk Safety secondary outcome selected significantly significantly lower therapy treated [DOI] 10.3346/jkms.2022.37.e102 PMC 바로가기 [Article Type] Article
Patients diagnosed with COVID-19 and treated with anakinra: a real-world study in the USAObservational Study Published on 2022-04-042022-10-05 Journal: Clinical and experimental immunology [Category] 임상, [키워드] Admission age Anakinra Analysis Antibiotics Clinical practice condition coronavirus disease Corticosteroids COVID-19 database database studies diagnosed diagnosed with COVID-19 died discharged Evidence finding hospital Hospital admission hyperinflammation ICU ICU admission intensive care interleukin (IL)-1 interleukin-1 receptor antagonist protein male mechanical ventilation Mortality Myocardial infarction Patient Real-world evidence receiving receptor renal required retrospective significantly higher significantly lower significantly shorter Standard deviation the mean treated Treatment USA [DOI] 10.1093/cei/uxab024 PMC 바로가기 [Article Type] Observational Study
Effectiveness of mRNA-1273, BNT162b2, and JNJ-78436735 COVID-19 Vaccines Among US Military Personnel Before and During the Predominance of the Delta Variant델타 변이형이 우세하기 전과 우세한 기간 동안 미군 병사들 사이에서 mRNA-1273, BNT162b2 및 JNJ-78436735 COVID-19 백신의 효과Article Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Antigen B.1.617.2 BNT162b2 booster dose booster doses case-control study Chain Reaction circulation Cohort conducted confounders Control COVID-19 COVID-19 vaccination COVID-19 vaccine decrease Defense defined Delta delta variant Department Effectiveness evaluated highest Hospitalization individual individuals JNJ-78436735 Laboratory logistic regression model lowest male median age mRNA mRNA-1273 mRNA-1273 vaccine Odds ratio outcome outcomes performed polymerase chain polymerase chain reaction positive SARS-CoV-2 delta SARS-COV-2 infection SARS-CoV-2 test significantly higher significantly lower stratified Support Surveillance symptomatic infection Symptoms test result the SARS-CoV-2 vaccination Vaccine variant variants of SARS-CoV-2 [DOI] 10.1001/jamanetworkopen.2022.8071 PMC 바로가기 [Article Type] Article
Serum zinc levels in pediatric patients with COVID-19Observational Study Published on 2022-04-012022-10-05 Journal: European journal of pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] Adults Analysis Antiviral effect association children conducted control group correlation COVID-19 Critical cut-off deficiency defined determine diagnosed with COVID-19 disease disease severity Factor growth Hospitalization hospitalizations Immunity incidence IQR living environment median median age neurologic participated Patient patients with COVID-19 Pediatric patient performed prospective observational study SARS-CoV-2 serum severity of COVID-19 Sex significantly higher significantly lower SPSS the median to define Variation window with COVID-19 Zinc [DOI] 10.1007/s00431-021-04348-w PMC 바로가기 [Article Type] Observational Study
Evaluation of the Roche-SD Biosensor rapid antigen test: Antigen is not reliable in detecting SARS-CoV-2 at the early stage of infection with respiratory symptomsRoche-SD Biosensor 급속 항원 검사 평가: 호흡기 증상이 있는 감염 초기 단계에서 SARS-CoV-2를 검출하는 항원은 신뢰할 수 없습니다.Article Published on 2022-04-012022-09-11 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 치료기술, [키워드] Antigen Asymptomatic biosensor children COVID-19 cross-reactivity early stage evaluated Infection less other respiratory virus Other respiratory viruses Rapid rapid antigen test respiratory symptom respiratory symptoms respiratory viruses Roche Roche-SD Biosensor SARS-CoV-2 SARS-CoV-2 virus sensitivity significantly lower Symptom [DOI] 10.1016/j.diagmicrobio.2021.115628 PMC 바로가기 [Article Type] Article
The effectiveness of motivational messages to intensive care unit nurses during the COVID-19 pandemicRandomized Controlled Trial Published on 2022-04-012022-10-05 Journal: Intensive & critical care nursing [Category] COVID19(2023년), SARS, 임상, [키워드] age Beck conducted control group COVID-19 COVID-19 pandemic Effectiveness form Hopefulness hopelessness hospital intensive care intensive care unit İstanbul life motivation multicentre Nurse Nurses Open-label optimism Orientation pandemic participant Randomized Satisfaction scale significantly higher significantly lower SMS statistically significant difference Test two group [DOI] 10.1016/j.iccn.2021.103161 PMC 바로가기 [Article Type] Randomized Controlled Trial
Liver or Kidney Transplantation After SARS-CoV-2 Infection: Prevalence, Short-term Outcome, and Kinetics of Serum IgG AntibodiesSARS-CoV-2 감염 후 간 또는 신장 이식: 혈청 IgG 항체의 유병률, 단기 결과 및 동역학Article Published on 2022-04-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Absolute level absolute levels acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 analyzed anti-S IgG antibody Chain Reaction Clinical sign Clinical signs Cohort Coronavirus-2 Course declined detectable died Follow-up IgG IgG antibodies IgG antibody Immunoglobulin Immunoglobulin G individuals Infection kidney Kinetics liver median median interval Nasopharyngeal swab one patient organ transplantation outcome Patient patients paucity of data polymerase chain polymerase chain reaction positive positively correlated Prevalence remained respiratory SARS-CoV-2 SARS-COV-2 infection selected seroconverted patient Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly lower solid organ solid organ transplantation symptom resolution transplantation Viral viral shedding [DOI] 10.1097/TP.0000000000003955 PMC 바로가기 [Article Type] Article
Successful early use of anti-SARS-CoV-2 monoclonal neutralizing antibodies in SARS-CoV-2 infected hematological patients – A Czech multicenter experienceSARS-CoV-2에 감염된 혈액학적 환자에서 항-SARS-CoV-2 단일클론 중화 항체의 성공적인 조기 사용 - 체코의 다기관 경험Multicenter Study Published on 2022-04-012022-09-12 Journal: Hematological oncology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] administration analyzed anti-CD20 anti-SARS-CoV-2 anti-SARS-CoV-2 monoclonal neutralizing antibodies Asymptomatic asymptomatic patient bamlanivimab baseline Casirivimab Cohort Combination Course COVID-19 COVID-19 diagnosis COVID-19 mortality COVID-19 symptom Critical death diagnose diagnosed early administration early-stage COVID-19 Efficacy evaluated Final first COVID-19 symptom Follow-up General population hematological Hematological malignancy Imdevimab impair Infection leukemia leukemias lymphoma lymphomas median Mild moderate monoclonal monoclonal antibody monotherapy Mortality multicenter multicentre Neutralizing neutralizing antibody neutralizing monoclonal antibody nine occurred Patient patients plasma positive remained Result SARS-CoV-2 significantly significantly lower Spike protein survival rate therapy treated were recorded [DOI] 10.1002/hon.2974 PMC 바로가기 [Article Type] Multicenter Study
Association of the IL-6R gene polymorphic variant rs2228145(C>A) with IL-6 gene polymorphisms in a healthy cohort of Turkish population Research Published on 2022-04-012022-10-05 Journal: Genes and Immunity [Category] 바이오마커, 유전자 메커니즘, [키워드] age allele allele G allelic association Bilirubin BMI body mass index Cohort collected Comorbidity Concentration Diseases evaluated explained fasting insulin Folic acid Frequency Gender Globulin healthy hematological parameters hormone IL-6 IL-6R IL-6R gene individuals Laboratory laboratory data laboratory parameter Liver function test loci locus majority monocyte neutrophil Platelets polymorphic variant polymorphism renal rs2228145 SHBG significantly higher significantly lower subject uric acid variant Variation White blood cells [DOI] 10.1038/s41435-022-00167-7 [Article Type] Research