48 hour – Page 3 – Communicable Diseases Research

Early Fall in C-Reactive Protein (CRP) Level Predicts Response to Tocilizumab in Rapidly Progressing COVID-19: Experience in a Single-Arm Pakistani Center

Internal Medicine

Published on 2021-11-302022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 48 hour A significant reduction Adequate age all-cause mortality baseline being category center Clinical data Clinical improvement confirmed COVID-19 case coronavirus disease COVID-19 COVID-19 disease COVID-19 treatment CRP CRP levels demonstrated disease dose Efficacy experience female ferritin level healthcare hospital identify in-hospital mortality inflammatory biomarkers intravenous tocilizumab Level magnitude majority objective outcome Oxygen requirement Oxygenation parameter Patient patients predict Primary outcome Protein receiving response Result secondary outcome Seven significantly increased survival outcome covid-19 the mean the patient Tocilizumab tocilizumab administration Treatment were recorded
[DOI] 10.7759/cureus.20031 PMC 바로가기 [Article Type] Internal Medicine

Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

SARS-CoV-2에 감염된 산모에게서 태어난 신생아의 면역 반응

Observational Study

Published on 2021-11-032022-09-10
Journal: JAMA Network Open [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] 48 hour 48 hours age antibody antibody production arbitrary unit association Birth breastmilk children Clinical outcome cohort study enrolled enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated explain exposure exposure to finding Follow-up gestational age IgA IgA antibodies IgA antibody IgG antibodies IgM antibodies IgM antibody immune complex Immune complexes immune response immune responses immune system Importance in utero Infant Infants infected with SARS-CoV-2 Infection infection with SARS-CoV-2 information investigated IQR Italy life male Maternal maternal age measure mother mucosal mucosal immune Neonatal Neonate Newborn objective occurred offspring participant parturition passive immunity Point positive Pregnancy pregnant women prospective cohort study PROTECT provided Receptor binding Receptor binding domain Relevance response Result Rome Saliva salivary SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike secretory IgA serum setting significantly higher significantly increased specific antibodies specific antibody specific IgG antibodies spike-specific antibodies Spike-specific antibody spike-specific IgG stimulate systemic immune response systemic immune responses tested transfer Transmission Umberto vertical transmission vertical virus transmission virus Virus spike virus transmission
[DOI] 10.1001/jamanetworkopen.2021.32563 PMC 바로가기 [Article Type] Observational Study

Severe Acute Respiratory Syndrome Coronavirus 2 Surveillance and Exposure in the Perioperative Setting With Universal Testing and Personal Protective Equipment Policies

중증 급성 호흡기 증후군 코로나바이러스 2 만능 검사 및 개인 보호 장비 정책을 통한 수술 전후 감시 및 노출

Article

Published on 2021-11-022022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술,

[키워드] 48 hour 48 hours acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Asymptomatic asymptomatic patients Cancer center Care center Chain Reaction city Community conducted Contact tracing coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 diagnostic endoscopy exposure flexible initial measure Memorial New York New York City Patient patients PCR cycle Perioperative Personal protective equipment Policy polymerase chain polymerase chain reaction positive postoperative postoperative period PPE presymptomatic Prevalence Protective respiratory SARS-CoV-2 SARS-COV-2 infection setting severe acute respiratory syndrome Coronavirus Spread surgery Surveillance surveillance testing sustainability tested Testing threshold Transmission unique Universal utility was done
[DOI] 10.1093/cid/ciaa1607 PMC 바로가기 [Article Type] Article

Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial

COVID-19가 있는 중환자의 장기 지원이 없는 날에 회복기 혈장의 효과: 무작위 임상 시험

Randomized Controlled Trial

Published on 2021-11-022022-09-12
Journal: JAMA [Category] MERS, 임상, 진단,

[키워드] 48 hour ABO-compatible convalescent plasma adjusted adverse event assigned benefit clinical convalescent plasma convalescent plasma group COVID-19 criterion Critically ill Critically ill patient cumulative Day days alive defined determine died domain Effect end point enrolled event Evidence futility greater hospital Ill Immunoglobulin IMPROVE In-hospital in-hospital mortality rate Inconclusive intensive care Intervention Invasive mechanical ventilation IQR less likelihood Logistic median median age Odds ratio Open-label organ organ support outcome Oxygenation participant Patient posterior probability primary analysis Primary outcome progression randomization Randomized receive REMAP-CAP reported secondary outcome Secondary outcomes Serious Adverse Events survival the median threshold Treatment treatment effect Trial venous thromboembolic Volume with COVID-19 women World Health Organization
[DOI] 10.1001/jama.2021.18178 PMC 바로가기 [Article Type] Randomized Controlled Trial

Reactions and COVID-19 disease progression following SARS-CoV-2 monoclonal antibody infusion

SARS-CoV-2 단일클론항체 주입 후 반응 및 COVID-19 질병 진행

Article

Published on 2021-11-012022-09-12
Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 임상, 진단,

Sample Processing and Stability for Urine Biomarker Studies

소변 바이오마커 연구를 위한 시료 처리 및 안정성

Article

Published on 2021-11-012022-09-11
Journal: The journal of applied laboratory medicine [Category] MERS, SARS, 바이오마커,

[키워드] 48 hour 48 hours acute kidney Acute kidney injury Alpha Biomarker Biomarkers biospecimen handling biospecimen storage centrifugation chitinase collected Concentration condition conditions COVID-19 COVID-19 pandemic current demonstrated determine Device Effect EGF epidermal epidermal growth factor Foley catheter freezing growth factor handling hospitalized patient IL-12p70 IL-13 IL-18 IL-1β IL-2 IL-4 IL-6 IL-8 interferon gamma interleukin investigated Kidney injury MCP-1 measurement monocyte monocyte chemoattractant protein-1 Necrosis neutrophil New notable osteopontin processing Protein protein stability reference standard remained Research robust Sample significant difference significant differences spot tested TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha UMOD Urinalysis urinalysis. Urine Variation variations were used YKL-40
[DOI] 10.1093/jalm/jfab082 PMC 바로가기 [Article Type] Article

Multisystem inflammatory syndrome in a neonate masquerading as surgical abdomen

수술 복부로 가장한 신생아의 다기관 염증 증후군

Case Reports

Published on 2021-10-282022-09-12
Journal: BMJ case reports [Category] MERS, SARS, 진단,

[키워드] 48 hour abdomen Administered anti-SARS-CoV-2 IgG cardiac cardiorespiratory Case report cerebrospinal fluid children clinical clinical response Contact COVID-19 Critically ill Culture D-dimer level D-dimer levels Dermatology Diagnosis drug elevated enzyme epidemiological Evidence ferritin Fever IMPROVE Infectious diseases Inflammatory inflammatory markers intensive care Intravenous immunoglobulin mimicking MIS-C mother Multiorgan dysfunction Neonatal neonatal and paediatric intensive care. Neonate outcomes peptide positive predominant presenting reported Stool surgical syndrome systemic steroids Urine with COVID-19
[DOI] 10.1136/bcr-2021-246579 PMC 바로가기 [Article Type] Case Reports

Thromboembolic Risk in COVID-19 Patients: Is There a Hidden Link?

Internal Medicine

Published on 2021-10-182022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 48 hour acute respiratory syndrome analyzed collected Computed tomography conducted coronavirus Course COVID-19 criteria D-dimer demonstrated determine Diagnosis eligible event Evidence FIVE for inclusion high risk higher risk hospital Hospital admission incidence Infectious disease Laboratory Mann-Whitney U test mortality rates no statistical difference Observational cohort study Occurrence Patient patients Pneumonia Predictive Pulmonary embolism Registered Result retrospective SARS-CoV-2 SARS-CoV-2 pneumonia Serum level single-center subsegmental t-test Thrombus two group venous thromboembolic disease Venous Thromboembolism VTE was used worse prognosis
[DOI] 10.7759/cureus.18850 PMC 바로가기 [Article Type] Internal Medicine

Influenza Management During the COVID-19 Pandemic: A Review of Recent Innovations in Antiviral Therapy and Relevance to Primary Care Practice

Review

Published on 2021-08-142022-10-04
Journal: Mayo Clinic Proceedings: Innovations, Quality & Outcomes [Category] 치료제,

[키워드] 48 hour addition antiviral therapy approach CDC, Centers for Disease Control and Prevention CDCCenters for Disease Control and Prevention center Centers for Disease Control and Prevention Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19, Coronavirus disease 2019 COVID-19coronavirus disease 2019 decreasing Diagnosis FDA, Food and Drug Administration FDAFood and Drug Administration Food and Drug Administration Health Service highlight Influenza Innovation management pandemic Practice Prevent prevention Prophylaxis PROTECT public health rapid influenza diagnostic test recent recommendation Relevance required resources review RIDT, rapid influenza diagnostic test RIDTrapid influenza diagnostic test SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2severe acute respiratory syndrome coronavirus 2 seasonal Seasonal influenza severe acute respiratory syndrome coronavirus 2 symptom onset Treatment treatment of influenza vaccination vaccination rate
[DOI] 10.1016/j.mayocpiqo.2021.07.005 PMC 바로가기 [Article Type] Review

Awake Prone Positioning Strategy for Nonintubated Hypoxic Patients with COVID-19: A Pilot Trial with Embedded Implementation Evaluation

Randomized Controlled Trial

Published on 2021-08-012022-10-05
Journal: Annals of the American Thoracic Society [Category] SARS, 임상,

[키워드] 48 hour 95% CI 95% confidence interval acute respiratory syndrome addressed Analysis Care clinical trial clinician Cluster collected conducted contraindication coronavirus coronavirus disease COVID-19 determine diffusion Effectiveness eligibility equity Factor feasibility fraction greater hospital hypoxia hypoxic patient identify implementation Implementation science less management measure median oxygen Oxygen requirement oxygen saturation participant Patient patients with COVID-19 penetration Pneumonia positioning positive Primary outcome prone prone positioning prone positioning strategy Randomized Randomized controlled trial Randomized controlled trials randomized trial Randomly SARS-CoV-2 semistructured interview Strategy study period therapeutic strategy translated Treatment Trial usual care with COVID-19
[DOI] 10.1513/AnnalsATS.202009-1164OC PMC 바로가기 [Article Type] Randomized Controlled Trial