Serious complications in COVID-19 ARDS cases: pneumothorax, pneumomediastinum, subcutaneous emphysema and haemothoraxOriginal Paper Published on 2021-06-082022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress Admission alveolar injury ARDS ARDS patient Blood cause caused Complication coronavirus COVID-19 COVID-19 ARDS patient criteria Diagnosis emphysema incidence increase Infection intensive care lactate dehydrogenase life-threatening mechanical ventilation morbidity Mortality mortality rate no statistical difference Novel coronavirus occurred onset of symptoms pathophysiology Patient patients PEEP Pneumomediastinum Pneumothorax Positive end-expiratory pressure Prone position reducing mortality risk factor SARS CoV-2 significantly statistically significant syndrome treated Treatment two group with COVID-19 [DOI] 10.1017/S0950268821001291 PMC 바로가기 [Article Type] Original Paper
Specific cytokines in the inflammatory cytokine storm of patients with COVID-19-associated acute respiratory distress syndrome and extrapulmonary multiple-organ dysfunctionResearch Published on 2021-06-042022-10-28 Journal: Virology Journal [Category] COVID-19, MERS, SARS, [키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome Admission AKI analyzed ARDS ARDS patient coagulation parameter contributed controls correlated COVID-19 COVID-19 patient COVID-19 patients creatinine cytokine Cytokine storm described died Disseminated intravascular coagulation dysfunction healthy volunteer IL-10 IL-6 IL-8 Inflammatory cytokine Inflammatory cytokine storm Laboratory laboratory data multiple organ dysfunction multiple-organ Multiple-organ dysfunction Necrosis negative correlation non-survivor PaO Patient patients with COVID-19 positive correlation recruited relative Result SARS-CoV-2 Serum level significantly Specific Survivors syndrome TNF-α urea nitrogen variable were measured [DOI] 10.1186/s12985-021-01588-y PMC 바로가기 [Article Type] Research
COVID-19 ARDS is characterized by higher extravascular lung water than non-COVID-19 ARDS: the PiCCOVID studyClinical Trial Published on 2021-06-012022-10-04 Journal: Critical Care [Category] MERS, 임상, [키워드] acute respiratory distress ARDS ARDS patient baseline characterized Cohort conducted COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 patients Diffuse alveolar damage dose ECMO exhibited extracorporeal membrane oxygenation fraction group groups hemodynamic Hemodynamic monitoring hospitals intensive care unit Lactate lung Lung inflammation Lung injury lung mechanics mechanical ventilation Mortality Non-COVID-19 outcome oxygen Oxygenation Patient patients with COVID-19 patients without COVID-19 prone positioning Registered remained reported Respiratory mechanics Result SARS-CoV-2 study period supplementary material syndrome the disease Thermodilution Transpulmonary thermodilution vascular permeability with COVID-19 [DOI] 10.1186/s13054-021-03594-6 PMC 바로가기 [Article Type] Clinical Trial
SARS-CoV-2 antibody immunoassays in serial samples reveal earlier seroconversion in acutely ill COVID-19 patients developing ARDS일련의 샘플에서 SARS-CoV-2 항체 면역 분석 결과 ARDS가 발병하는 급성 COVID-19 환자에서 조기 혈청 전환이 나타남Research Article Published on 2021-05-132022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome anti-SARS-CoV-2 Antibody testing ARDS ARDS patient ARDS patients clinical evaluation Cohort cohorts conducted COVID-19 pandemic COVID-19 patient determine diagnostics Disease prevalence Elecsy Elecsys ELISA Germany healthy subject IgA IgG immunoassay individual Lubeck marker objective occurred Patient patients PCR-negative Population potential risk Rate respiratory distress Respiratory distress syndrome Result risk marker Roche Diagnostics SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antibody testing sensitivities Seroconversion serum side significantly higher Specificities specificity specimen stratified suggested Switzerland syndrome tested therapeutic utility were measured were used [DOI] 10.1371/journal.pone.0251587 PMC 바로가기 [Article Type] Research Article
Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome급성 호흡 곤란 증후군이 있는 중환자 COVID-19 환자의 IFN-I 활성 및 면역 프로파일에 대한 종단 평가Clinical Trial Published on 2021-04-122022-08-13 Journal: Critical Care [Category] MERS, 바이오마커, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome alteration appear ARDS ARDS patient ARDS patients Bacterial sepsis cellular COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine cytokine levels Cytokines decrease described Elevation expression followed by Hospital stay ICU admission IFN response IFN-I IFN-stimulated gene IFN-stimulated genes IFNα2 immune immune parameter Immune profile immune response immune responses immuno-inflammatory Immunosuppression intensity ISG longitudinal longitudinal immune monitoring lymphocyte Lymphocyte count marker mHLA-DR non-survivor normal values Occurrence outcome pandemic plasma question respiratory distress Result SARS-CoV2 infection Secondary infection secondary infections Sepsis similarities similarity supplementary material Survivors syndrome TNF-α Type-I IFN [DOI] 10.1186/s13054-021-03558-w PMC 바로가기 [Article Type] Clinical Trial
COVID-19 and non-COVID ARDS patients demonstrate a distinct response to low dose steroids- A retrospective observational studyObservational Study Published on 2021-04-012022-10-05 Journal: Journal of critical care [Category] SARS, 임상, [키워드] ARDS ARDS patient COVID-19 CRP greater highlight immunological phenotype implication Inflammation low dose low-dose PaO Patient physiological retrospective statistically significant steroid treatment Steroids with COVID-19 [DOI] 10.1016/j.jcrc.2020.11.012 PMC 바로가기 [Article Type] Observational Study
Ethnic and age-specific acute lung injury/acute respiratory distress syndrome risk associated with angiotensin-converting enzyme insertion/deletion polymorphisms, implications for COVID-19: A meta-analysis인종 및 연령별 급성 폐 손상/급성 호흡 곤란 증후군 위험, 안지오텐신 전환 효소 삽입/제거 다형성, COVID-19에 대한 시사점: 메타 분석Meta-Analysis Published on 2021-03-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] 95% CI 95% confidence interval ACE acute lung injury acute respiratory distress syndrome addressed Adults ALI/ARDS allele analyses Analysis angiotensin Angiotensin-converting enzyme ARDS ARDS patient ARDS patients article Asian Asians assessment association associations Bonferroni correction Caucasian Caucasians children CIs Comparisons conducted coronavirus disease Coronavirus disease 2019 covariate covariates COVID-19 distress dominant Ethnicity examined genetic model Genotype healthy control healthy controls heterogeneity I/D I/D polymorphism implication include indicated insertion/deletion life lung Lung injury Meta-analysis meta-regression Mortality Odds ratios outcome outlier pandemic Patient patients with COVID-19 polymorphism Polymorphisms Regression reported respiratory distress Respiratory distress syndrome risk robust robustness Significant Statistical power statistically Subgroup analyses subgroup analysis syndrome therapy Topic Treatment was performed [DOI] 10.1016/j.meegid.2020.104682 PMC 바로가기 [Article Type] Meta-Analysis
Risk factors analysis of COVID-19 patients with ARDS and prediction based on machine learningArticle Published on 2021-02-032022-10-04 Journal: Scientific Reports [Category] MERS, 바이오마커, 임상, [키워드] Accuracy age Analysis ARDS ARDS patient AST AUC biochemical build Care caused China Clinical characteristics Clinical data clinical feature clinical manifestation collected Comorbidity consolidation cough COVID-19 COVID-19 ARDS patient COVID-19 patient COVID-19 patients CRP deep learning-based method develop diagnostic distress Epidemiology Factor Health hypertension indicated Infectious disease LDH lung Lymphocyte count machine learning algorithm mild patient NLR Older Patient predict Predictive medicine Probability Region resources responsible Result Risk factors secondary bacterial infection Sensitivity and specificity severe COVID-19 significantly strongly related susceptible syndrome the median ventilator were used [DOI] 10.1038/s41598-021-82492-x PMC 바로가기 [Article Type] Article
Timing of VV‐ECMO therapy implementation influences prognosis of COVID‐19 patientsObservational Study Published on 2021-02-012022-10-04 Journal: Physiological Reports [Category] MERS, 임상, [키워드] acute respiratory distress age Algorithm All the patient Analysis ARDS ARDS patient BMI clinician cohort study conducted COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 pandemic CPAP criteria Critically ill current defined died ECMO extracorporeal membrane oxygenation Geneva University Hospital had more HFNO hospital Hypoxemia ICU implementation influence information knowledge Local mechanical ventilation mechanical ventilation duration Medicine nasal onset of symptom Patient Pneumonia positive airway pressure Prognosis registry data Result retrospective selected significantly shorter Society supported survival rate survivor syndrome therapy VV‐ECMO [DOI] 10.14814/phy2.14715 PMC 바로가기 [Article Type] Observational Study
Pressure Injury Prevention in COVID-19 Patients With Acute Respiratory Distress SyndromeMedicine Published on 2021-01-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome ARDS ARDS patient caused China Chronic illness coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient develop eye guidelines Health Healthcare professional hospital IMPROVE infection control Injury intensive care measure mild symptoms Older Oxygenation pandemic Patient Perspective pressure Pressure injury pressure points prevention professionals promote Prone position prone positioning Protective recommendation reduce respiratory Respiratory mechanics risk SARS-CoV-2 Supine position syndrome the patient Ventilation while worsening hypoxemia [DOI] 10.3389/fmed.2020.558696 PMC 바로가기 [Article Type] Medicine