Heterologous gam-COVID-vac (sputnik V)/mRNA-1273 (moderna) vaccination induces a stronger humoral response than homologous sputnik V in a real-world data analysisArticle Published on 2022-10-012022-11-15 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 진단, [키워드] adjusted adverse effect age Analysis Anti-spike binding antibody unit binding domain boost Combination Complete Concentration COVID COVID-19 doses enrolled evaluated event female Frequency Gam-COVID-Vac Gender Heterologous Heterologous scheme homologous humoral humoral immune response IgG immunization increase individual induce interquartile range IQR Linear model median Mild moderate Moderna mRNA-1273 participant RBD real-world data required SARS-CoV-2 Serological assay Seven significantly significantly higher vaccination Vaccine [DOI] 10.1016/j.cmi.2022.05.009 PMC 바로가기
Reduced humoral response to a third dose (booster) of SARS-CoV-2 mRNA vaccines by concomitant methotrexate therapy in elderly patients with rheumatoid arthritisArticle Published on 2022-10-012022-11-15 Journal: RMD Open [Category] COVID19(2023년), SARS, 진단, [키워드] Affect binding antibody unit BNT162b2 booster booster vaccination Concomitant concomitant treatment COVID-19 disease dose Efficacy Elderly patient had no Health authority humoral humoral immune response IgG increase IQR Kruskal-Wallis test median methotrexate monotherapy mRNA vaccine mRNA vaccines mRNA-1273 Musculoskeletal Patient patients PROTECT RBD receiving Receptor binding domain reduce reduced Rheumatoid rheumatoid arthritis risk SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccination second dose severe COVID-19 shown significantly the SARS-CoV-2 therapy treated vaccination was measured younger patient [DOI] 10.1136/rmdopen-2022-002632 PMC 바로가기
Comparison of antibody response durability of mRNA-1273, BNT162b2, and Ad26.COV2.S SARS-CoV-2 vaccines in healthcare workersArticle Published on 2022-10-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 진단, [키워드] Ad26.COV2.S Administered age analysis of variance Anti-spike anti-spike antibody antibody level Antibody Response Antibody responses blood draws BNT162b2 BNT162b2 vaccine booster dose COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccinations Effectiveness enzyme-linked immunosorbent female group healthcare worker Immunosuppression interquartile range IQR Linear regression median mRNA-1273 mRNA-1273 vaccine neutralizing antibody outcome participant Participants Primary outcome SARS-CoV-2 SARS-CoV-2 vaccine significantly significantly higher vaccination Vaccine vaccine effectiveness variable [DOI] 10.1016/j.ijid.2022.08.022 PMC 바로가기
COVID-19 Vaccination in Autoimmune Diseases (COVAD) study: Vaccine safety in idiopathic inflammatory myopathiesArticle Published on 2022-10-012022-11-15 Journal: Muscle & nerve [Category] 진단, [키워드] Active disease ADE ADEs adverse event analyzed Autoimmune benefit BNT162b2 collected comparable COVID-19 COVID-19 vaccination dermatomyositis Descriptive statistics disease dose evaluate HCs healthy control higher risk Hydroxychloroquine IBM Immunoglobulin impacted inactive Inflammatory inflammatory disorder International interquartile range investigated IQR less lower risk Major median age multivariable Myopathy myositis nine Odds ratio outcome Patient Pfizer postvaccination Rash recipients reported rheumatology risk severe COVID-19 vaccination Vaccine was performed [DOI] 10.1002/mus.27681 PMC 바로가기
A machine-learning algorithm for diagnosis of multisystem inflammatory syndrome in children and Kawasaki disease in the USA: a retrospective model development and validation studyArticle Published on 2022-10-012022-11-16 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy age Algorithm Boston Care center characteristic Child childhood children clinician collected Connecticut COVID-19 pandemic develop development diagnosed Diagnosis Diego disease distribution Early detection enrolled Eunice Kennedy Shriver External feature febrile febrile illness first stage FIVE foundation group heart hospital hospitals Human illness illnesses Inflammatory initial IQR Kawasaki disease laboratory measurements library Los Angele machine-learning median Medicine MIS-C Patient Prevent retrospective SARS-COV-2 infection severe complications similarity stratified syndrome systemic inflammation Treatment USA validation study Washington [DOI] 10.1016/S2589-7500(22)00149-2 PMC 바로가기
Serological response to SARS-CoV-2 vaccination in patients with inflammatory rheumatic disease treated with disease modifying anti-rheumatic drugs: A cohort study and a meta-analysisArticle Published on 2022-10-012022-11-15 Journal: Joint bone spine [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome addition Antibody Response biologic Cohort cohort study conducted coronavirus COVID-19 COVID-19 pandemic disease evaluated identify IgG antibody immune-mediated diseases impair individuals Inflammatory Inflammatory rheumatic diseases IQR leflunomide less management median age Meta-analysis methotrexate observational study Older participant Patient performed Prevalence reported rheumatic disease rituximab robust Sample size SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV2 vaccination second vaccination seroconversion rate seroconverted serological response significantly Spike protein suggested targeted therapy Therapies therapy treated two-dose regimen vaccination Vaccine were measured [DOI] 10.1016/j.jbspin.2022.105380 PMC 바로가기
Level of Diffusion and Training of Lung Ultrasound during the COVID-19 Pandemic – A National Online Italian Survey (ITALUS) from the Lung Ultrasound Working Group of the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI)Article Published on 2022-10-012022-11-15 Journal: Ultraschall in der Medizin (Stuttgart, Germany : 1980) [Category] 진단, [키워드] Analgesia Anesthesia anesthesiologist carried clinical impact Course COVID-19 COVID-19 case COVID-19 pandemic diffusion English evaluated First wave group ICU intensive care intensive care unit IQR Italian Italy Level lung material median pandemic Patient physician Quantitative reported Resuscitation Society survey the median training Ultrasound working [DOI] 10.1055/a-1634-4710 PMC 바로가기
Targeted SARS-CoV-2 treatment is associated with decreased mortality in immunocompromised patients with COVID-19Article Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 변종, 진단, 치료제, [키워드] age anti-SARS-CoV-2 Antiviral case sery choice circulating variants COVID-19 curative curative treatment death death rate decreased mortality died Efficacy Follow-up Immunocompromised patient Immunocompromised patients IQR median monoclonal antibodies monoclonal antibody omicron outcome Patient Prophylaxis receive recorded Remdesivir reported retrospective Safe SARS-CoV-2 treatment severe adverse event severe COVID-19 significantly lower Tolerance treated patient treated patients Treatment treatment availability Treatment protocol with COVID-19 [DOI] 10.1093/jac/dkac253 PMC 바로가기
Seroepidemiological study of factors affecting anti-spike IgG antibody titers after a two-dose mRNA COVID-19 vaccination in 3744 healthy Japanese volunteersArticle Published on 2022-09-292022-11-15 Journal: Scientific Reports [Category] 진단, [키워드] 1.26 Adverse reaction affecting age anti-S anti-S antibody anti-S IgG anti-Spike IgG antibody Antibody titer Antibody titers BNT162b2 vaccine conducted COVID-19 vaccination cross-sectional dose Effect elapsed Factor Factors female females Gender healthy healthy volunteer identify IgG antibody titer immunosuppressants immunosuppressive IQR Japanese magnitude median age mRNA mRNA-1273 mRNA-1273 vaccine Multiple positive questionnaire SARS-COV-2 infection significantly smoking tested the vaccine therapy vaccination Vaccine Volunteer [DOI] 10.1038/s41598-022-20747-x PMC 바로가기
Obesity is associated with a higher Torque Teno viral load compared to leannessArticle Published on 2022-09-282022-11-15 Journal: Frontiers in Endocrinology [Category] 진단, [키워드] 95% CI acute respiratory syndrome Affect age Analysis association Bariatric surgery BMI confounder coronavirus coronavirus disease disease disease-associated Diseases fasting insulin Follow-up Host immune function immunocompetence in viral independent individual Infectious disease interleukin 6 IQR linear modeling marker median obese obesity outcome outcomes participant PCR positively correlated proportion quantified reflect rising risk risk factor risk stratification subjects torque torque teno virus viral immune response Viral load virus vitamin D levels weight loss [DOI] 10.3389/fendo.2022.962090 PMC 바로가기