The Influence of Maternal Factors on Neonatal Intensive Care Unit Admission and In-Hospital Mortality in Premature Newborns from Western Romania: A Population-Based StudyObservational Study Published on 2022-05-262022-10-05 Journal: Medicina [Category] 임상, [키워드] accelerate Admission advanced age affecting age Antibiotics Care cause Characteristics contributed COVID-19 pandemic death death rate demographic data determine develop European Evolution Factor global public health Health services Hospitalization In-hospital in-hospital mortality Infant Infection influence intensive care intensive care unit less likelihood material Maternal morbidity Mortality Neonatal neonatal intensive care unit Neonatal Mortality Neonate Neonates Newborn NICU admission objective obstetrics outcome pandemic Patient Pregnancy Premature premature birth Prematurity required resource Result Retrospective study risk factor Risk factors Romania significant difference significantly statistically significant Steroids Support sustainable development goal therapy understanding union variable while [DOI] 10.3390/medicina58060709 PMC 바로가기 [Article Type] Observational Study
CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patientsCMV 혈청 양성은 비노인 환자에서 심각한 COVID-19에 대한 잠재적인 새로운 위험 요소입니다Article Published on 2022-05-252022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] absence advanced age affected Analysis Biomarker CMV co-morbidities Cohort cohorts Comorbidities confirmation COVID-19 Critical cross-reactivity cytomegalovirus deaths detectable disease disease severity distribution finding herpes simplex herpes simplex virus higher risk Hypothesis ICU IgG individual individuals intensive care investigated Mild Mild disease moderate morbidities occur older patients Patient performed prediction Prevalence representing risk factor SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serology Seropositivity serostatus severe COVID-19 severe disease statistical Support T cell T cells were used with mild disease [DOI] 10.1371/journal.pone.0268530 PMC 바로가기 [Article Type] Article
Induction of humoral and cellular immune responses to COVID-19 mRNA and vector vaccines: A prospective cohort study in Bulgarian healthcare workersCOVID-19 mRNA 및 벡터 백신에 대한 체액 및 세포 면역 반응의 유도: 불가리아 의료 종사자를 대상으로 한 전향적 코호트 연구Article Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] advanced age age anti-SARS-CoV-2 immune responses anti-SARS-CoV-2 vaccine anti-SARS-CoV-2 vaccines BNT162b2 Bulgarian cellular Cellular immune response circulating Cohort comparable Complete coronavirus disease Coronavirus disease 2019 correlated Course COVID-19 COVID-19 vaccine Donor donors dose Enumeration evaluated healthcare worker humoral humoral immune response IFNγ IgA immune responses Immunity immunization Immunoglobulin immunoglobulin A increased risk induce induction Infection Installing interferon gamma Longevity Messenger RNA mRNA mRNA vaccine Neutralizing activity neutralizing antibody overcome Pandemics participant peaking priming prospective cohort study protective immunity Receptor-binding domain SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 specific T-cell significantly single dose T cell T cells tested Vaccine vaccine cohort virus-neutralizing virus-neutralizing antibody virus-neutralizing antibody. [DOI] 10.1002/jmv.27572 PMC 바로가기 [Article Type] Article
Reduced COVID-19 mortality linked with early antibodies against SARS-CoV-2, irrespective of age연령에 관계없이 SARS-CoV-2에 대한 조기 항체와 연결된 COVID-19 사망률 감소Article Published on 2022-04-012022-09-11 Journal: European journal of internal medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료법, [키워드] Admission advanced age age Anti-spike antibody Antibody Response clinical assessment Clinical outcome co-morbidity Concentration COVID-19 COVID-19 infection COVID-19 mortality COVID-19 pandemic Cox regression model Critical death died discharged disease severity early phase early stage Efficiency elderly Elderly patient elderly patients functional healing hospital Hospital stay Hospitalization Humoral immunity IgG IgG levels IgM immune system Immunological response In-hospital death indicated lymphopenia modulate Mortality multivariate Multivariate Cox regression models Older outcome outcomes Patient produced PROTECT Protein risk risk factor SARS-CoV-2 serum Serum level serum levels stratified subject subjects therapeutic strategy titer [DOI] 10.1016/j.ejim.2022.02.010 PMC 바로가기 [Article Type] Article
Determinants of persistence of symptoms and impact on physical and mental wellbeing in Long COVID: A prospective cohort studyLong COVID에서 증상의 지속성과 신체적 정신적 웰빙에 미치는 영향의 결정 요인: 전향적 코호트 연구Article Published on 2022-04-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Admission advanced age analyzed breathlessness consequence contribute COVID COVID-19 COVID-19 patients determinant Duration fatigue female gender Health Hospital admission Hospitalized ICU identify independent predictor independent predictors Long Long COVID males Mental Patient persistence physical Physical health Population predictor predictors prospective cohort prospective cohort study Psychological distress residual Residual symptoms risk factor Risk factors Symptom Symptom persistence. symptomatic Symptoms the median were assessed [DOI] 10.1016/j.jinf.2022.02.003 PMC 바로가기 [Article Type] Article
COVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea Research Published on 2022-03-292022-10-05 Journal: Scientific Reports [Category] SARS, 임상, 치료기술, 치료법, [키워드] advanced age airway appear approach Asthma change control group COPD COVID-19 COVID-19 positive subject COVID-19 symptom declined dehydration elevated Germany Hydration hypertonic increase India magnitude oxygen saturation Oxygenation protocol random reduced reducing Respiratory disease risk SARS-COV-2 infection significantly subject suppressed Symptom Treatment upper airway [DOI] 10.1038/s41598-022-08609-y [Article Type] Research
Smoking Status and Factors associated with COVID-19 In-Hospital Mortality among US VeteransObservational Study Published on 2022-03-262022-10-05 Journal: Nicotine & tobacco research : official journal of [Category] Coronavirus, SARS, 임상, [키워드] 95% confidence interval 95%CI adjusted odds ratio advanced age Analysis association cascade Comorbidity complications Control COVID-19 current diabete Diabetes Mellitus examined Factor Factors former granular higher risk highlighting hospital Hospitalization Hospitalized in-hospital mortality increased risk Kidney disease logistic regression models lower risk Mortality nonsteroidal anti-inflammatory drug NSAIDS obesity outcome Patient patients with COVID-19 positive Presence primary analysis reported resource retrospective cohort study risk risk of death SARS-CoV-2 SARS-COV-2 infection smoker Smokers smoking smoking status status tested the United State Unknown variable veteran with COVID-19 [DOI] 10.1093/ntr/ntab223 PMC 바로가기 [Article Type] Observational Study
Sero-survey on long-term care facility residents reveals increased risk of sub-optimal antibody response to BNT162b2: implications for breakthrough prevention장기 치료 시설에 대한 혈청 서브 거주자는 BNT162B2에 대한 하위 최적 항체 반응의 위험이 증가 함을 나타냅니다 : 획기적인 예방에 대한 시사점Research Published on 2022-03-102022-09-10 Journal: BMC Geriatrics [Category] 치료법, [키워드] acute respiratory syndrome coronavirus administration advanced age Antibody Response Antibody titer Antibody titers association BNT162b2 Cancer Care caused Comorbidities Comorbidity Complete confidence confidence interval coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid therapy COVID-19 death diabetes Diabetes Mellitus diagnosis of COVID-19 dose evaluate Factor Health care Health care worker humoral Humoral response humoral responses IgG implication increased risk individual investigated Italian Logistic regression Long term care facilities Long-term care maintenance Measures medium multivariate logistic regression nucleocapsid Older age positive serology predictor previous diagnosis reduced risk Reinfection resident respiratory response to vaccination Result reveal S-IgG antibodies SARS-CoV-2 SARS-CoV-2 specific antibodies SARS-CoV-2 specific antibody serological response serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease supplementary material vaccination Vaccine [DOI] 10.1186/s12877-022-02884-0 PMC 바로가기 [Article Type] Research
Sero-survey on long-term care facility residents reveals increased risk of sub-optimal antibody response to BNT162b2: implications for breakthrough preventionResearch Published on 2022-03-102022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] administration advanced age Antibody Response Antibody titer association BNT162b2 Cancer Care caused Comorbidities Comorbidity Complete confidence coronavirus 2 coronavirus disease Corticosteroid corticosteroid therapy COVID-19 death Diabetes Mellitus diagnosis of COVID-19 dose evaluate Factor Health care worker humoral humoral responses IgG implication increased risk individual investigated Italian Long term care facilities Measures medium multivariate logistic regression Older age positive serology predictor reduced risk Reinfection resident respiratory response to vaccination Result reveal S-IgG antibodies SARS-CoV-2 SARS-CoV-2 specific antibody serological response severe disease supplementary material vaccination Vaccine [DOI] 10.1186/s12877-022-02884-0 PMC 바로가기 [Article Type] Research
Sero-survey on long-term care facility residents reveals increased risk of sub-optimal antibody response to BNT162b2: implications for breakthrough preventionResearch Published on 2022-03-102022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] administration advanced age Antibody Response Antibody titer association BNT162b2 Cancer Care caused Comorbidities Comorbidity Complete confidence coronavirus 2 coronavirus disease Corticosteroid corticosteroid therapy COVID-19 death Diabetes Mellitus diagnosis of COVID-19 dose evaluate Factor Health care worker humoral humoral responses IgG implication increased risk individual investigated Italian Long term care facilities Measures medium multivariate logistic regression Older age positive serology predictor reduced risk Reinfection resident respiratory response to vaccination Result reveal S-IgG antibodies SARS-CoV-2 SARS-CoV-2 specific antibody serological response severe disease supplementary material vaccination Vaccine [DOI] 10.1186/s12877-022-02884-0 PMC 바로가기 [Article Type] Research