Reactogenicity after heterologous and homologous COVID-19 prime-boost vaccination regimens: descriptive interim results of a comparative observational cohort studyObservational Study Published on 2022-05-312022-10-05 Journal: BMC Infectious Diseases [Category] Coronavirus, 임상, [키워드] adjusted Adverse Adverse drug reaction age age and sex AstraZeneca BNT162b2 boost ChAdOx1 Cohort comparable Complete COVID-19 dose Efficacy Factor Frequency Gender Health Heterologous homologous immunization individual Moderna mRNA vaccine mRNA-1273 mRNA-vaccine mRNA-vaccines Observational cohort study observational study pandemic participant problem proportion reaction reactogenicity regimen regimens reported resource survey vaccination Vaccines were assessed with COVID-19 [DOI] 10.1186/s12879-022-07443-x PMC 바로가기 [Article Type] Observational Study
Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study네덜란드 의료 종사자의 4가지 다른 SARS-CoV-2 백신에 의해 유도된 SARS-CoV-2 변이체에 대한 항체 반응: 전향적 코호트 연구Article Published on 2022-05-172022-09-11 Journal: PLoS Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Ad26 Ad26.COV2.S Adenovirus adenovirus vector-based vaccines adjusted age and sex Alpha Analysis Antibody Response Antibody titers AZD1222 Beta BNT162b2 booster booster vaccination cellular immunity COV2.S Delta Effectiveness Fold change followed by Gamma geometric geometric mean geometric mean titers GMT group groups head Head-to-head comparison Health care Health care worker highest include initial lack limitation linear mixed model Linear regression mRNA mRNA vaccine mRNA vaccines mRNA-1273 Netherlands neutralization neutralize Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers of BNT162b2 omicron Omicron variant performed prospective cohort prospective cohort study recipient recipients recognize reduction in SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants sera serum vaccination Vaccine variant VoC VOCs was performed was reduced wild-type [DOI] 10.1371/journal.pmed.1003991 PMC 바로가기 [Article Type] Article
Clinical course and outcomes of COVID-19 patients with chronic obstructive pulmonary disease: A retrospective observational study in Wuhan, ChinaObservational Study Published on 2022-05-062022-10-05 Journal: Medicine [Category] 임상, [키워드] acute exacerbation Admission age age and sex Analysis analyzed China chronic obstructive clinical Clinical course Clinical outcome clinical outcomes Comorbidity COPD coronavirus disease correlated Course COVID-19 COVID-19 patient Cox regression death diagnosis of COVID-19 Dyspnea exhibited Hospitalization Huoshenshan Hospital Infection Inflammation Inflammatory responses Injury intensive care Kaplan-Meier Laboratory test mechanical ventilation outcome pathophysiology Patient performed proportion pulmonary disease Randomly regression analysis Respiratory failure respiratory tract retrospective Retrospective study selected severe COVID-19 subsequent two groups viral clearance was performed Wuhan Wuhan, China [DOI] 10.1097/MD.0000000000029141 PMC 바로가기 [Article Type] Observational Study
Safety and immunogenicity of CoronaVac in people living with HIV: a prospective cohort studyHIV 감염자에 대한 CoronaVac의 안전성 및 면역원성: 전향적 코호트 연구Article Published on 2022-05-012022-09-12 Journal: The Lancet. HIV [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adjusted age and sex antiretroviral baseline Brazil CD4 CD4 cell CD4 count Cell Complete Concentration concerning control group CoronaVac COVID-19 vaccine delayed response geometric mean titre highlight HIV HIV/AIDS IgG immunogenicity Immunosuppression IMPROVE inactivated increase in independent intramuscularly investigated IQR less median multivariable model NAb activity neutralising antibody outpatient clinic participant people with HIV positive prospective cohort study recruited reduced reported Safety SARS-CoV-2 IgG SARS-CoV-2 vaccine second dose serious adverse reaction Seroconversion seroconversion rates titre two-dose regimen university vaccination Vaccine vaccine administration vaccine dose vaccine immunogenicity Vaccines Viral load was collected with HIV [DOI] 10.1016/S2352-3018(22)00033-9 PMC 바로가기 [Article Type] Article
COVID-19 among workers of a comprehensive cancer centre between first and second epidemic waves (2020): a seroprevalence study in Catalonia, Spain1차와 2차 전염병 사이(2020) 종합 암 센터 직원 사이의 COVID-19: 스페인 카탈로니아의 혈청 유병률 연구Article Published on 2022-04-212022-09-11 Journal: BMJ Open [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI 95% CIs adjusted age and sex antibody association blood sample Cancer cancer centre Care Complete Contact contact with COVID-19 COVID-19 infection COVID-19 patients cross-sectional study epidemic wave epidemiological survey Epidemiology Factor female First wave HCW HCWs Health Health care health care workers Health Education healthcare worker Healthcare workers higher risk hospitals household Infection median age medical staff no difference no differences no significant differences Nursing outcome pandemic Patient prevalence ratio Prevent preventive measure preventive measures reported risk factor SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 seroprevalence Serological testing seropositive participant seropositive participants Seropositivity Seroprevalence Severe COVID-19 Infection significant difference Sociodemographic characteristics Spain Spanish Surveillance the SARS-CoV-2 Transmission with COVID-19 [DOI] 10.1136/bmjopen-2021-056637 PMC 바로가기 [Article Type] Article
Clinical efficacy and safety of high-flow nasal cannula (HFNC) in acute hypoxaemic patients with COVID-19: a protocol for a systematic review and meta-analysisCOVID-19를 가진 급성 저산소병 환자에서 고유 유량 코 캐뉼라 (HFNC)의 임상 효능 및 안전성 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2022-04-122022-08-31 Journal: BMJ Open [Category] meta-analysis, [키워드] Acute respiratory failure adult intensive & age and sex approach Caregivers clinical Clinical efficacy Cochrane Library Continuous data COVID-19 COVID-19 patient COVID-19 patients Critical Critical care data extraction determine develop disease severity Efficacy and safety eligibility criteria Ethical approval Ethics evaluate for inclusion HFNC High-flow nasal cannula hypoxaemic respiratory failure identify increased risk Infection transmission infections Intensive intensive care intensive care unit intubation mean difference meta-analyses Meta-analysis Mortality nasal nasal cannula outcome Participants Patient peer-reviewed performed Primary outcome PROSPERO protocol randomised controlled trial RCT RCTs registration number required respiratory Respiratory failure respiratory infections risk risk of bia risk ratio secondary outcome Secondary outcomes Subgroup analyses subgroup analysis systematic review the mean Treatment undergo Web of Science [DOI] 10.1136/bmjopen-2021-057743 PMC 바로가기 [Article Type] Article
ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29 512 patientsObservational Study Published on 2022-04-022022-10-05 Journal: BMC Anesthesiology [Category] 임상, [키워드] ABO ABO blood group acute respiratory distress addition adjusted Admission Adult patient age and sex analysed analyses Antigen assessment association Blood Blood Group Blood group antigen cells circulation Cohort COVID-19 cohort Critical care Critically ill critically ill patients days alive demonstrated diagnose disease eligible Epidemiology erythrocytes failure FIVE for inclusion groups ICUs inotrope intensive care intensive care unit invasive ventilation morbidity morbidity and mortality Mortality multicentre multivariable regression model multivariable regression models no difference no significant difference observation outcome Patient patient population previous study Region RhD blood group. Scania sensitivity analysis Sepsis Septic shock subgroup subgroups subgroups of patient Support syndrome trauma unique Vasopressor Ventilation [DOI] 10.1186/s12871-022-01626-4 PMC 바로가기 [Article Type] Observational Study
Population differences in antibody response to SARS-CoV-2 infection and BNT162b2 vaccinationSARS-CoV-2 감염과 BNT162b2 백신 접종에 대한 항체 반응의 인구 차이Article Published on 2022-04-012022-09-12 Journal: FASEB journal : official publication of the Federa [Category] COVID19(2023년), SARS, 진단, [키워드] age age and sex anti-SARS-CoV-2 Anti-viral immunity antibodies antibody antibody level Antibody Response BNT162b2 Cohort complex composed Concentration correlated COVID-19 COVID-19 patient COVID-19 symptoms COVID-19 vaccine decrease elicited Factor humoral IgG antibodies infected with SARS-CoV-2 Infection magnitude maintain males of BNT162b2 participant Population primary determinant recipient recipients repeated SARS-CoV-2 SARS-COV-2 infection serum antibodies serum sample severity Sex spike protein RBD Support susceptible vaccination Vaccine [DOI] 10.1096/fj.202101492R PMC 바로가기 [Article Type] Article
Sex- and age specific association of new-onset atrial fibrillation with in-hospital mortality in hospitalised COVID-19 patientsResearch article Published on 2022-04-012022-10-05 Journal: IJC Heart & Vasculature [Category] 바이오마커, [키워드] 95% CI age age and sex analysed analyses association Atrial fibrillation calculated cardiac arrhythmias cohort study Coronavirus disease 2019 COVID-19 COVID-19 cohort COVID-19 patient demographics disease disorder electrical Female patients heart failure hospitalisation hospitalised COVID-19 patient impacted in-hospital mortality increased mortality increased risk International male median age Mortality multicentre multivariable multivariable logistic regression occur Occurrence Older Patient Prevalence Prognosis prognostic effect Result risk Sex significantly stratified ventricular arrhythmia [DOI] 10.1016/j.ijcha.2022.100970 [Article Type] Research article
COVID-19 in Cirrhotic Patients: Is Portal Vein Thrombosis a Potential Complication?Observational Study Published on 2022-03-262022-10-05 Journal: Canadian journal of gastroenterology & hepatology [Category] 임상, [키워드] 2019 coronavirus disease abdomen absence age and sex C-reactive protein cirrhosis comorbid disease complete blood count control group Coronavirus infection COVID-19 cross-sectional D-dimer demonstrated diabete diagnosed disease Doppler Doppler ultrasound Elderly patient evaluate Follow-up HCC hepatocellular Hepatocellular carcinoma hypertension incidence infected with COVID-19 involved liver Liver cirrhosis Occurrence Patient PCR portal portal vein thrombosis Potential Prospective Study renal function Serum ferritin significant difference the patient Thromboembolic event thrombosis two group underlying disease Vein venous thromboembolic [DOI] 10.1155/2022/5900468 PMC 바로가기 [Article Type] Observational Study