Immunogenicity and reactogenicity after heterologous prime-boost vaccination with CoronaVac and ChAdox1 nCov-19 (AZD1222) vaccinesCoronaVac 및 ChAdox1 nCov-19(AZD1222) 백신으로 이종 프라임-부스트 백신 접종 후 면역원성 및 반응성Article Published on 2022-11-302022-09-12 Journal: Human vaccines & immunotherapeutics [Category] MERS, 진단, [키워드] 95% CI 95% confidence interval Administered age age and sex antibody assigned AZD1222 binding domain booster dose Care ChAdOx1 nCoV-19 Cohort cohorts Combination Concentration control group CoronaVac COVID-19 COVID-19 pandemic effective elicited enrolled finding geometric mean ratio GMR Health Heterologous heterologous prime-boost homologous immune response immunogenicity indicated mass participant primary endpoint prime-boost interval RBD reactogenicity robust Safe the median vaccination Vaccine vaccine administration vaccine combination. while [DOI] 10.1080/21645515.2022.2052525 PMC 바로가기 [Article Type] Article
Multiplex PCR Detection of Respiratory Tract Infections in SARS-CoV-2-Negative Patients Admitted to the Emergency Department: an International Multicenter Study during the COVID-19 PandemicArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome Adults age age and sex association Bacterial caused Characteristics children circulating coronavirus coronavirus disease country COVID-19 COVID-19 pandemic detect detection determine diagnostic Emergency emergency department etiological agent Europe Evidence hospital human coronavirus Human rhinovirus Infection Intervention logistic regression model métapneumovirus Middle East multicenter study Multiplex PCR multiplex PCR assay Nasopharyngeal swab pandemic Panel pathogen Patient PCR prevalent respiratory respiratory pathogen respiratory syncytial virus respiratory tract respiratory tract infection respiratory viruses SARS-CoV-2 significantly higher Stratification Symptom symptomatic Symptoms target targets tested tract utility variety viral infection viruses [DOI] 10.1128/spectrum.02368-22 PMC 바로가기
Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learningResearch article Published on 2022-10-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] age and sex attribute bioinformatics chronic disease Comorbidity complex country COVID-19 COVID-19 disease severity data extraction Delta demonstrated Effect effort fixed GISAID heterogeneous include information Interpretation lack logistic regression models machine learning Meta-analysis Metadata Mild Mutation obesity omicron outcome pandemic Patient Predictive random random effect reduction in Repository risk robust SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 spike protein sequence severe disease severity Spike protein submitted subset time-consuming training vaccination variant viral genome sequence viral genomics virus while [DOI] 10.1016/j.compbiomed.2022.105969 [Article Type] Research article
Using EHR data to identify coronavirus infections in hospitalized patients: Impact of case definitions on disease surveillanceArticle Published on 2022-10-012022-11-15 Journal: International journal of medical informatics [Category] COVID19(2023년), SARS, 치료제, [키워드] age and sex anti-IL6 Antiviral Case definition Characteristics Clinical diagnosis clinically cohort characteristics Complication coronavirus disease Coronavirus infection COVID COVID-19 diagnosed Disease surveillance EHR data Electronic health records. evaluate evaluated Health health system Hospitalized Hydroxychloroquine identify Impact Inpatient lab Laboratory laboratory confirmation Laboratory test laboratory-confirmed Myocardial infarction outcome outcomes overall mortality Patient patients hospitalized positive receive Record required SARS-CoV-2 The United States therapy with COVID-19 [DOI] 10.1016/j.ijmedinf.2022.104842 PMC 바로가기
Analysis of 52 240 source plasma donors of convalescent COVID-19 plasma: Sex, ethnicity, and age association with initial antibody levels and rate of dissipationArticle Published on 2022-10-012022-11-15 Journal: Journal of clinical apheresis [Category] COVID19(2023년), SARS, 진단, [키워드] Abbott SARS-CoV-2 IgG African American age age and sex anti-SARS-CoV-2 antibody anti-SARS-CoV-2 titer antibody Antibody titer Antibody titers approved Asian association CCP convalescent convalescent COVID-19 plasma convalescent plasma COVID-19 Critically ill patient demographics donation Donor Efficacy elevated evaluate Evaluating Factor faster Frequency group help Hispanic hyperimmune hyperimmune globulins inclusion criteria individual initial lowest MOST Native nucleocapsid plasma plasma donor demographics. SARS-CoV-2 screened the United State therapy treat Variability was performed with COVID-19 [DOI] 10.1002/jca.21998 PMC 바로가기
Seroprevalence of SARS-CoV-2 infection in the Tyrolean district of Schwaz at the time of the rapid mass vaccination in March 2021 following B.1.351-variant outbreakArticle Published on 2022-09-092022-11-15 Journal: Frontiers in Public Health [Category] SARS, 변종, 진단, [키워드] age and sex Anti-N Anti-spike B.1.351 variant Beta blood sample circulating collected Comirnaty Coverage determine dissemination distribution immunization implementation individual Infection infections IQR median age Neutralizing antibodies outbreak Prevalence proportion questionnaire recruited SARS-CoV-2 SARS-COV-2 infection Seropositivity Seroprevalence susceptible Symptom undocumented infection unique vaccination vaccine dose were used [DOI] 10.3389/fpubh.2022.989337 PMC 바로가기
Vaccination willingness in association with personality traits in patients with multiple sclerosis in the course of SARS-CoV-2 pandemicArticle Published on 2022-09-072022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] acceptance age and sex association Characteristics collected Course Depression detect determinant disease course Extraversion Follow-up follow-up assessment ill patients investigated majority measure multiple sclerosis pandemic Patient patients proportion Psychological questionnaire SARS-CoV-2 pandemic SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines seeking Self-directedness Sex significantly socio-demographic the SARS-CoV-2 vaccination Vaccines variable [DOI] 10.1038/s41598-022-18912-3 PMC 바로가기
Humoral response among patients with interstitial lung disease vaccinated with the BNT162b2 SARS-Cov-2 vaccine: a prospective cohort studyObservational Study Published on 2022-09-012022-10-05 Journal: Respiratory Research [Category] SARS, 임상, 진단, [키워드] addition age and sex Anti-inflammatory Anti-inflammatory therapy anti-inflammatory treatments Anti-spike antibody Antibody titer antifibrotic therapy BNT162b2 BNT162b2 vaccine caused Cohort conducted control group dose evaluate evaluated healthy control high risk humoral Humoral response ILD immune response Immunosuppression Interstitial lung disease IPF maintain median Messenger RNA Patient patients patients treated patients with ILD prospective cohort study pulmonary fibrosis Rabin Medical Center SARS-CoV-2 vaccine serology test seronegative seropositive Severe COVID-19 Infection significantly lower the healthy therapy treated Treatment vaccination vaccine dose was reduced [DOI] 10.1186/s12931-022-02155-x PMC 바로가기 [Article Type] Observational Study
Long COVID symptoms in SARS-CoV-2-positive children aged 0-14 years and matched controls in Denmark (LongCOVIDKidsDK): a national, cross-sectional studyArticle Published on 2022-09-012022-10-04 Journal: The Lancet. Child & adolescent health [Category] COVID19(2023년), SARS, 임상, [키워드] absence acute phase age age and sex children clinically clinics conducted Control control group controls COVID cross-sectional defined Denmark Descriptive statistics develop difference emotional female foundation greater had more Health Hedge higher odd infected with SARS-CoV-2 intensity inventory IQR life Logistic regression analysis Long long-lasting male median mother National Older outcome PCR test positive Prevalence prevalent Psychological Quality Quality of life question Registered response SARS-COV-2 infection SARS-CoV-2 test sick Somatic statistically significant Symptom Symptoms were used [DOI] 10.1016/S2352-4642(22)00154-7 PMC 바로가기 [Article Type] Article
Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune ResponsesArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술, [키워드] Abbott acute respiratory syndrome Affect affected affecting age age and sex analyzed anti-SARS-CoV-2 antibody Antibody detection BAU binding antibody unit BNT162b2 cellular Cellular immune response cellular immune responses ChAdOx1 nCoV-19 coronavirus correlation Cutoff demonstrated determine Effect Elecsy evaluated Factor female first vaccination Genscript group humoral humoral immune responses immune immune response immune responses interferon gamma investigated male mix-and-match vaccine mRNA mRNA vaccine mRNA-1273 neutralizing antibody predict Qiagen QuantiFERON RBD regimen regimens relationship response robust Roche SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 neutralization second vaccination Sex subject T cell response T cell responses the receptor-binding domain vaccination Vaccine vaccine group vector vector vaccine venous blood was collected were used [DOI] 10.1128/spectrum.02495-21 PMC 바로가기