Applying the WHO-ICRC BEC course to train emergency and inpatient healthcare workers in Sierra Leone early in the COVID-19 outbreakResearch Article Published on 2022-02-142022-10-28 Journal: BMC health services research [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] added Applying assessment assessments baseline basic Basic emergency care course capacity building Care Committee conducted country Course COVID-19 COVID-19 outbreak COVID-19 pandemic Critical disease dissemination effort Emergency Emergency and critical care enrolled feasibility feasible Future Health services health system healthcare worker hospital implementation knowledge knowledge score National outbreak overlap P -value participant Participants proportion prospective cohort study provided Red resource Result Student’s t-test supplementary material sustained training treating was increased West World Health Organization [DOI] 10.1186/s12913-022-07556-8 PMC 바로가기 [Article Type] Research Article
Applying WHO COVID-19 workforce estimate tools remotely in an African context: a case report from Mali and KenyaCase Study Published on 2022-01-282022-10-31 Journal: Human Resources for Health [Category] Coronavirus, SARS, [키워드] African applied Applying approach Case report challenge country COVID-19 COVID-19 cases COVID-19 pandemic demonstrated estimator Europe feasibility Health health system health systems health worker health workforce help implementation Indicator Kenya Local Mali management measure medications methodology National office oxygen pandemic Patient Planning predict predicted Regional resource respond Support the timing treat WHO WISN workload Workload modelling World Health Organization [DOI] 10.1186/s12960-021-00653-5 PMC 바로가기 [Article Type] Case Study
Mutations in viral nucleocapsid protein and endoRNase are discovered to associate with COVID19 hospitalization risk바이러스 뉴클레오캡시드 단백질 및 endoRNase의 돌연변이가 COVID19 입원 위험과 관련이 있는 것으로 밝혀졌습니다Article Published on 2022-01-242022-09-10 Journal: Scientific Reports [Category] 변종, 유전자 메커니즘, 치료법, [키워드] Applying association change characterized clinical status coding Cohort Computational biology and bioinformatics correlation correlations COVID COVID-19 COVID-19 patient COVID19 Cytokine storms Diseases eight form functional genetics Haplotype Hospitalization IMPROVE in viral independent Inpatient inpatient status lead Molecular biology Non-synonymous nucleocapsid protein nucleotide occur Outpatient P -value peaked Protein q-values replicated residue residues risk SARS-CoV-2 selected sequenced severe COVID-19 significantly Single nucleotide variant SNV SNVs Spike protein state statistically significant synonymous the Spike Transmissibility triggering variant variants Viral viral genomes viral sequence viral sequences Viral variants Washington [DOI] 10.1038/s41598-021-04376-4 PMC 바로가기 [Article Type] Article
Air Quality of Work, Residential, and Traffic Areas during the COVID-19 Lockdown with Insights to Improve Air QualityArticle Published on 2022-01-102022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Air pollutants Air quality ambient Applying AQI Area average changes in city comparable Concentration COVID-19 decrease effective evaluate the effect implication indicated insight investigated lockdown measure Nitrogen oxides Ozone Quality Riyadh selected Traffic work [DOI] 10.3390/ijerph19020727 PMC 바로가기 [Article Type] Article
Applying Human-Centered Design Principles to Digital Syndromic Surveillance at a Mass Gathering in India: ViewpointViewpoint Published on 2022-01-102022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] agency Applying assumption change clinician COVID-19 pandemic design Digital Digital health Electronic health record Government Health Human centered design India individual Intervention mass mHealth Mobile health populations principle resource Satisfaction Surveillance Syndromic surveillance [DOI] 10.2196/27952 PMC 바로가기 [Article Type] Viewpoint
The deuce-ace of Lassa Fever, Ebola virus disease and COVID-19 simultaneous infections and epidemics in West Africa: clinical and public health implicationsReview Published on 2021-12-302022-10-28 Journal: Tropical Medicine and Health [Category] COVID-19, [키워드] African Applying approach caused Co-infection Community COVID-19 COVID-19 pandemic Diseases Ebola virus disease Endemic Epidemics epidemiological exacerbated Healthcare system Healthcare systems highlight human-to-animal transmission implication include Infection Infectious disease Lassa fever limitation morbidity and mortality Occurrence one health Other outbreak pandemic pathophysiological feature porous public health reported resource response risk silent Spread Surveillance tropical West West Africa zoonotic [DOI] 10.1186/s41182-021-00390-4 PMC 바로가기 [Article Type] Review
Expected and observed in‐hospital mortality in heart failure patients before and during the COVID‐19 pandemic: Introduction of the machine learning‐based standardized mortality ratio at Helios hospitalsClinical Investigations Published on 2021-12-232022-10-31 Journal: Clinical Cardiology [Category] COVID-19, SARS, [키워드] 95% confidence interval administrative data age Algorithm applied Applying calculate characteristic COVID‐19 COVID‐19 pandemic data set death deaths Diagnosis discharge event rate Evidence expected expected mortality heart failure Helio hospital hospital admission rate indicated Inpatient machine learning Mortality mortality prediction mortality rate no significant difference Observed pandemic Patient Probability Randomly reported Result SARS‐CoV‐2 infection stratified subgroup tested Volume were excluded [DOI] 10.1002/clc.23762 PMC 바로가기 [Article Type] Clinical Investigations
Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2Article Published on 2021-12-202022-10-04 Journal: NPJ Vaccines [Category] 비임상, [키워드] acute respiratory syndrome administration Applying binding cellular response clinical trial comparable coronavirus demonstrated DNA plasmid DNA vaccine DNA vaccines dominant IgG immune responses immunogenic Intradermal intramuscular intranasal lung Lung infection mice neutralizing antibody New Plasmid platform Preclinical protective effect rhesus macaque rhesus macaques robust Safe SARS-CoV-2 Spike protein tested Th1 the SARS-CoV-2 the vaccine Vaccine vaccine platform viral pathogens viral replication [DOI] 10.1038/s41541-021-00419-z PMC 바로가기 [Article Type] Article
Deciphering early-warning signals of SARS-CoV-2 elimination and resurgence from limited data at multiple scalesLife Sciences–Mathematics interface Published on 2021-12-152022-10-30 Journal: Journal of the Royal Society Interface [Category] COVID-19, SARS, [키워드] adaptive Applying approaches Control COVID-19 effective reproduction numbers Effectiveness epidemic wave Evidence fusing hidden Hong Kong imported cases Infectious disease Infectious diseases information Intervention likelihood Local local transmission New occur real time regions response SARS-CoV-2 SARS-CoV-2 elimination Support Surveillance sustained Transmission transmission potential Victoria [DOI] 10.1098/rsif.2021.0569 PMC 바로가기 [Article Type] Life Sciences–Mathematics interface
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formationArticle Published on 2021-12-142022-10-04 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, [키워드] accumulated Alternative pathway analyzed Applying attenuate autophagy biogenesis Cell cellular chronic liver disease contribute COVID-19 different diseases disparate driving elevated fraction HCV hepatitis C virus highlighting host cell identify in viral involved Lipid mechanism membrane vesicle morphologically organelle pathway pharmacological phylogenetically proteomics purified recruited Replication responsible RNA virus RNA viruses SARS-CoV-2 SARS-CoV-2 replication therapy virus viruses [DOI] 10.1038/s41467-021-27511-1 PMC 바로가기 [Article Type] Article