VitaminD supplementation for the prevention and treatment of COVID-19: a position statement from the Spanish Society of Geriatrics and GerontologyResearch article Published on 2021-05-012022-10-05 Journal: Revista española de geriatría y gerontología [Category] 치료법, [키워드] acute phase Administered Adults advanced age anti-inflammatory effect bilateral pneumonia chronic condition Clinical practice coronavirus disease COVID-19 dendritic cell dose dysregulation Evidence expressed frailty Gerontology hospitalized COVID-19 patients hyperinflammatory cytokine storm immune immune cells immune function immune system IMPROVE Inflammation lack macrophages modulate Monocytes morbidity and mortality Older Older adults over Patient patients with COVID-19 Prevent receptor recommendation reported SARS-CoV-2 severe respiratory symptom shown Society Spanish T lymphocytes treat Treatment VDR Vitamin D vitamin D deficiency Vitamin D supplementation [DOI] 10.1016/j.regg.2021.02.001 [Article Type] Research article
Clinical characteristics of SARS-CoV-2 pneumonia diagnosed in a primary care practice in Madrid (Spain)마드리드(스페인)의 1차 진료에서 진단된 SARS-CoV-2 폐렴의 임상적 특징Observational Study Published on 2021-04-292022-09-01 Journal: BMC Family Practice [Category] MERS, SARS, 임상, 진단, [키워드] age Bilateral bilateral pneumonia Blood blood test body mass body mass index C-reactive protein Chain Reaction Characteristics chest X-ray clinical Clinical characteristics Clinical data clinical manifestation clinical manifestations collected Comorbidities Complication cough COVID-19 Day death described diabete diabetes diagnosed Diagnosis diagnostic test diagnostic tests dyslipidaemia Dyspnoea Electronic health record Electronic health records female Fever Gastrointestinal disturbances group Hospitalised patients hypertension Infection lymphocyte Lymphocytes MOST Nasopharyngeal swab occurred outcome Patient patients with SARS-CoV-2 Physical examination Pneumonia pneumonias prevalent primary care Pulmonary embolism pulse oximetry Result Retrospective study reverse transcriptase reverse transcriptase-polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia Spain Standard deviation stratified supplementary material the mean the SARS-CoV-2 [DOI] 10.1186/s12875-021-01430-y PMC 바로가기 [Article Type] Observational Study
Myelodysplastic syndrome in a 30-year-old man with coronavirus disease 2019 (COVID-19): a diagnostic challengeClinical Case Report Published on 2021-04-232022-10-27 Journal: Autopsy & Case Reports [Category] COVID-19, [키워드] addition Affect Analysis bilateral pneumonia Bone marrow cells chills clinical evaluation Combination condition coronavirus disease coughing COVID-19 COVID-19 patients Cytogenetics cytopenia demonstrated diagnosed Diagnosis diagnostic Dizziness dysplastic feature Fever flow cytometry hospital Hospitalization immunohistochemistry individual male management MDs Mild mimicking moderate molecular molecular feature Mutation Myelodysplastic syndrome myelodysplastic syndromes myelofibrosis neutrophil occur pathologic Patient patients patients with COVID-19 Peripheral blood raised reactive repeated reported SARS-CoV-2 Sequencing SF3B1 Shortness of breath subsequent weakness [DOI] 10.4322/acr.2021.274 PMC 바로가기 [Article Type] Clinical Case Report
Upregulation of CCR4 in activated CD8 + T cells indicates enhanced lung homing in patients with severe acute SARS‐CoV‐2 infection활성화된 CD8 + T 세포에서 CCR4의 상향 조절은 중증 급성 SARS-CoV-2 감염 환자에서 향상된 폐 귀환을 나타냅니다Clinical Trial Published on 2021-04-192022-08-13 Journal: European Journal of Immunology [Category] MERS, SARS, 임상, 진단, [키워드] activated Activation affected antibody antibody secreting cell antibody secreting cells bilateral pneumonia CCR4 CD4 CD4 and CD8 T cells CD8 CD8 T cell CD8 T cells Chemokine receptor chemokine receptor CCR4 contribute COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 differentiation disease effective effector cell expressed healthy donor healthy donors helper cells homing homing receptors hyperinflammation Hypothesis immune activation immune system immunological change immunological changes immunological phenotype independent independent of indicate lung Lung homing lung trafficking Lungs majority Mild NK‐/B‐cell Pathogenesis Patient Phenotypes Pneumonia proliferation promote pulmonary complication pulmonary complications pulmonary symptom pulmonary symptoms pulmonary toxicity raise receptor Respiratory failure responses SARS‐CoV‐2 infection SARS‐CoV2 infection SARS‐CoV‐2 severity significantly T cell T cells T‐cell T‐cell activation T‐cell exhaustion T‐follicular helper cell T‐follicular helper cells T‐cell activation therapeutic agents upregulation [DOI] 10.1002/eji.202049135 PMC 바로가기 [Article Type] Clinical Trial
Characteristics of a COVID-19 confirmed case series in primary care (COVID-19-PC project): a cross‐sectional study1차 진료(COVID-19-PC 프로젝트)에서 COVID-19 확인 사례 시리즈의 특성: 횡단면 연구Observational Study Published on 2021-04-082022-09-01 Journal: BMC Family Practice [Category] MERS, SARS, 임상, 진단, [키워드] adjusted age analysed attending physician Atypical bilateral pneumonia care provider carried case sery Chain Reaction Clinical course collected community transmission confirmed case Contact contact with Coronavirus infections cough COVID COVID-19 COVID-19 [Supplementary Concept] COVID-19 case Descriptive analysis diagnosed disease severity Dyspnoea electronic medical record electronic medical records encounter Factor Fever follow-up period Health Health Service Health services healthcare healthcare professionals hospital Infection male medical records mild respiratory Older Patient PCR Pneumonia Poisson regression model polymerase chain polymerase chain reaction Prevalence primary care Primary Health Care recorded required resource respiratory respiratory infection Result retrospective risk factor Risk factors SARS-CoV-2 service Sociodemographic Spain statistical analysis subject Symptom variable Viral was performed women [DOI] 10.1186/s12875-021-01419-7 PMC 바로가기 [Article Type] Observational Study
COVID-19-associated leukocytoclastic vasculitis leading to gangrene and amputationCase Report Published on 2021-04-062022-10-30 Journal: IDCases [Category] COVID-19, [키워드] acute respiratory syndrome affected amputation Antibiotics antibodies antibody bilateral pneumonia Brain chest X-ray complex connective tissue coronavirus COVID-19 disease event feature Fever Gangrene Hospital stay initial investigated laboratory investigation limb male Necrosis outcome Patient Pneumonia positive presenting progression Rash required SARS-CoV-2 skin lesion skin rash stroke suffered Swab the patient therapy type 2 diabete Vasculitis weakness [DOI] 10.1016/j.idcr.2021.e01117 PMC 바로가기 [Article Type] Case Report
Corticosteroids and tocilizumab reduce in-hospital mortality in severe COVID-19 pneumonia: a retrospective study in a Spanish hospital코르티코스테로이드와 토실리주맙은 심각한 COVID-19 폐렴에서 병원 내 사망률을 감소시킵니다: 스페인 병원의 후향적 연구Article Published on 2021-04-012022-09-12 Journal: Infectious diseases (London, England) [Category] MERS, 진단, [키워드] 1:1 Antibiotic treatment Antiviral bilateral pneumonia caused Cohort Combination Combined Corticosteroid Corticosteroids COVID-19 death defined entire cohort evaluated examined fraction hospital immunomodulators immunomodulatory in-hospital mortality in-hospital mortality rate Methylprednisolone Mortality oxygen oxygen saturation Patient patients Pneumonia pulse oximetry receiving reduce reduce mortality reduced retrospective cohort study Retrospective study risk risk of death SARS-CoV-2 severe COVID-19 Severe COVID-19 pneumonia severe pneumonia significantly lower Spanish Tocilizumab treated Treatment university hospital was performed [DOI] 10.1080/23744235.2021.1884286 PMC 바로가기 [Article Type] Article
Elevated Monocyte to Lymphocyte Ratio and Increased Mortality among Patients with Chronic Kidney Disease Hospitalized for COVID-19Article Published on 2021-03-222022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Admission age bilateral pneumonia Cancer cause caused chronic Chronic kidney disease CKD Complication confidence interval confounders contribute coronavirus disease cough COVID-19 D-dimer death Diagnosis died disease Dyspnea entire cohort Factor ferritin Fever Health Hospitalization hypoxia identify immune function in-hospital mortality Increased increased risk infection complications infections Kidney disease laboratory parameter majority male males MLR monocytes-to-lymphocyte ratio Mortality Multivariate analysis Odds ratio Patient patients evaluated procalcitonin proportion Ratio remained risk stratification significantly higher statistically significant Symptom vaccine response with COVID-19 [DOI] 10.3390/jpm11030224 PMC 바로가기 [Article Type] Article
Targeting Cytokine Storm in COVID-19: A Role of Online Hemodiafiltration with Asymmetric Cellulose Triacetate in Maintenance Hemodialysis Patients—A Report of 10 CasesCase Series Published on 2021-03-122022-11-01 Journal: Case Reports in Nephrology [Category] COVID-19, [키워드] Analysis asymmetric baseline bilateral pneumonia Biomarker Blood carried Case series case sery Cellulose characteristic Course COVID-19 Diagnosis dialysis died disease drug effective evaluate favor hemodiafiltration Hemodialysis Hospital admission Hospitalization Hyperinflammatory IL-6 immunomodulatory effect Infection Inflammatory Inflammatory mediators less maintenance membrane membranes moderate outcome parameter Patient patients with SARS-CoV-2 Pneumonia positive predominant radiological reduce reduction in report required role SARS-CoV-2 severe pneumonia storm suggested susceptible systemic inflammation targeting tested the cytokine storm the disease the patient therapeutic therapeutic approaches therapeutic option those who survived variety [DOI] 10.1155/2021/5575928 PMC 바로가기 [Article Type] Case Series
Acute Coronary Syndrome and COVID-19: A Case Report of Refractory HypercoagulabilityCardiac/Thoracic/Vascular Surgery Published on 2021-03-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Acute coronary syndrome acute respiratory distress Anticoagulants anticoagulation antiplatelet ARDS bilateral pneumonia bilateral pulmonary infiltrate Care coronavirus disease COVID-19 COVID-19 infection descending Diabetic difficulty breathing discharged DVT elevated Follow-up hypercoagulability ICU male management mechanical ventilation Myocardial infarction Myocardial ischemia novel Pain Patient patients Physical examination positive Precaution Protective refractory report syndrome the patient therapeutic therapy thrombosis troponin levels X-ray [DOI] 10.7759/cureus.13675 PMC 바로가기 [Article Type] Cardiac/Thoracic/Vascular Surgery