Biobank – Page 3 – Communicable Diseases Research

SARS-CoV-2 infection in alpha1-antitrypsin deficiency

알파1 항트립신 결핍증에서 SARS-CoV-2 감염

Article

Published on 2021-08-012022-09-11
Journal: Respiratory medicine [Category] 변종,

Immunogenicity of the BNT162b2 COVID-19 mRNA vaccine and early clinical outcomes in patients with haematological malignancies in Lithuania: a national prospective cohort study

BNT162b2 COVID-19 mRNA 백신의 면역원성과 리투아니아 혈액암 환자의 초기 임상 결과: 국가 전향 코호트 연구

Article

Published on 2021-08-012022-09-12
Journal: The Lancet. Haematology [Category] MERS, SARS, 진단,

[키워드] Abbott Abstract Adverse Affect age allogeneic HSCT anti-CD20 antibody Antibody Response Architect autologous Biobank blood sample BNT162b2 BNT162b2 vaccine circulating Clinical outcome clinically Cohort Community Concentration Course COVID-19 death dose doses Efficacy evaluate event genotyping haematological malignancy Health health-care healthy heterogeneous highest IgG IgG antibody immunogenicity Infection Intervention Lithuania main analysis malignancies malignancy material median Microparticle mRNA vaccination mRNA vaccine National negatively affected of BNT162b2 Older participant Patient patients with haematological Pfizer-BioNTech prospective cohort study questionnaire Registered response responses ruxolitinib SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 vaccine second dose serological response seronegative serum severe SARS-CoV-2 subgroup therapy translation treated Treatment tyrosine kinase inhibitor university untreated patient vaccination vaccine dose vaccine doses venetoclax Vilnius was done was used were assessed
[DOI] 10.1016/S2352-3026(21)00169-1 PMC 바로가기 [Article Type] Article

Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

통합 게놈 분석은 COVID-19 입원의 기저에 있는 감수성 유전자를 식별합니다

Article

Published on 2021-07-272022-09-12
Journal: Nature Communications [Category] 바이오마커, 신약개발, 유전자 메커니즘, 진단, 치료제,

[키워드] affecting Analysis association Biobank Biomarkers Clinical symptoms Coagulation contribute Control COVID COVID-19 COVID-19 hospitalization COVID-19 Host Genetics Initiative COVID-19 severity described disease severity Effect expression Genetic association study genetic loci genetics Genome-wide association studies Genome-wide association study genomic highlight Hospitalization host genetics host inflammatory response identify Immunologic individual Infection Inflammation initiative Japan mechanism mRNA expression pathway Pathways phenome predicted protein level protein levels proteome rapid progress replicate SARS-COV-2 infection severity splicing susceptibility Transcriptome viral infection with COVID-19
[DOI] 10.1038/s41467-021-24824-z PMC 바로가기 [Article Type] Article

Pre-analytical sample handling effects on blood cytokine levels: quality control of a COVID-19 biobank

혈액 사이토 카인 수준에 대한 분석 전 샘플 취급 효과 : Covid-19 Biobank의 품질 관리

Research Article

Published on 2021-07-222022-09-01
Journal: Biomarkers in Medicine [Category] MERS, SARS, 진단,

Differential psychological response to the COVID-19 pandemic in psychiatric inpatients compared to a non-clinical population from Germany

Original Paper

Published on 2021-07-152022-10-31
Journal: European archives of psychiatry and clinical neuro [Category] COVID-19, MERS,

A longitudinal SARS-CoV-2 biorepository for COVID-19 survivors with and without post-acute sequelae

급성 후유증이 있거나없는 코비드 -19 생존자를위한 종 방향 SARS-COV-2 Biorepository

Research Article

Published on 2021-07-132022-09-01
Journal: BMC Infectious Diseases [Category] SARS, 진단,

[키워드] acute COVID-19 acute infection All participants Biobank biobanking Biorepository clinical trial clinically cognitive collected Community coronavirus COVID-19 death demographic data dependent on Diagnosis disease dysfunction enrolled exercise intolerance fatigue Follow-up globe hospital Hospitalization Hospitalized identify Infection initial knowledge Long-hauler longitudinal Loss of Smell loss of taste nasopharyngeal participant PASC pathophysiology Patient PCR phenotype physical positive post infection Post-acute sequelae of COVID-19 (PASC) provide questionnaire recruited reduce Registered reported required Research researcher response responses Result risk Saliva SARS-CoV-2 SARS-COV-2 infection significantly more specimens Spectrum Stool Surveillance survivor Symptom Symptoms symptoms of COVID-19 targeted intervention targeted interventions Taste Treatment vaccination valuable resource Viral viral pathology
[DOI] 10.1186/s12879-021-06359-2 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 Infection in Health Workers: Analysis from Verona SIEROEPID Study during the Pre-Vaccination Era

의료 종사자의 SARS-CoV-2 감염: 백신 접종 전 시대의 베로나 SIEROEPID 연구 분석

Article

Published on 2021-06-142022-09-10
Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% CI analyzed Antibody detection Antibody titre baseline Biobank Cohen’s kappa contribute COVID-19 dataset Demographic variables enrolled epidemiological Health health worker health workers hospital IgA IgG IgG and IgM IgM Immunological response increase in Italy Laboratory test Laboratory tests large sample longitudinal design management National number of infected risk Risk assessment SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection sensitivity serological test Serological tests Serosurvey Serum level specificity Spread spring statistically statistically significant Support Surveillance Swab Swab test swabs unit university university hospital vaccination Verona virus working
[DOI] 10.3390/ijerph18126446 PMC 바로가기 [Article Type] Article

High-throughput framework for genetic analyses of adverse drug reactions using electronic health records

전자 건강 기록을 사용한 부작용 반응의 유전자 분석을위한 고 처리량 프레임 워크

Research Article

Published on 2021-06-012022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] added ADR ADRS Adverse drug reaction Adverse drug reactions Adverse reaction Adverse reactions allergy Analysis approach association associations Biobank clinical guideline Clinical guidelines common diseases conducted CYP2D6 develop DNA drug Drug allergy drug response Electronic health record Electronic health records eligible patient Eligible patients Evidence expression genetic association genetic associations genetic loci Genetic studies genetic study Genetic variation Genome-wide association studies Genome-wide association study group GWAS Healthcare system help identify IMPROVE individual less loci opioid OPRM1 pathophysiological mechanism pathophysiological mechanisms phenome physiological Precision proof Quantitative recorded Research response sample sizes understanding university
[DOI] 10.1371/journal.pgen.1009593 PMC 바로가기 [Article Type] Research Article

Evaluation of Production Lots of a Rapid Point-of-Care Lateral Flow Serological Test Intended for Identification of IgM and IgG against the N-Terminal Part of the Spike Protein (S1) of SARS-CoV-2

SARS-CoV-2의 스파이크 단백질(S1)의 N-말단 부분에 대한 IgM 및 IgG 식별을 위한 Rapid Point-of-Care 측면 흐름 혈청학적 테스트의 생산 로트 평가

Article

Published on 2021-05-312022-09-01
Journal: Viruses [Category] 진단,

SARS-CoV-2 Viremia is Associated With Inflammatory, But Not Cardiovascular Biomarkers, in Patients Hospitalized for COVID-19

SARS-CoV-2 바이러스혈증은 COVID-19로 입원한 환자의 심혈관 바이오마커가 아닌 염증성 질환과 관련이 있습니다

Observational Study

Published on 2021-05-042022-08-31
Journal: Journal of the American Heart Association [Category] MERS, SARS, 바이오마커, 임상, 치료기술,

[키워드] association baseline Biobank Biomarker Biomarkers C-reactive protein cardiac troponin cardiac troponin T cardiovascular collected comparable Concentration concentrations COVID COVID-19 COVID‐19 cTnT D-dimer diabetes Diabetes Mellitus dimer Elevation elevations ferritin had more Hospitalization hospitalized patient hospitalized patients infection with SARS-CoV-2 Inflammatory Inflammatory biomarker interleukin interleukin-6 laboratory-confirmed lower oxygen saturation Manifestations mechanical ventilation men Myocardial dysfunction myocardial injury N-terminal N-terminal pro-B-type natriuretic peptide NT-proBNP observational study occur oxygen Patient patients peptide plasma plasma sample prevalent procalcitonin Registration Result RNA SARS-CoV-2 SARS-CoV-2 RNA SARS‐CoV‐2 Stress symptoms of COVID-19 tissue troponin T variety Viremia white
[DOI] 10.1161/JAHA.120.019756 PMC 바로가기 [Article Type] Observational Study