cell damage
[용어속성] Symptom
The Emerging Role of Neutrophils in the Pathogenesis of Thrombosis in COVID-19
Review
[키워드] activate
aggregation
cell damage
chemokine
circulation
contributing to
COVID-19
COVID-19 patients
Endothelitis
highlighting
IL-8
immunothrombosis
Infection
Innate immunity
killing
mechanism
mechanisms
morbidity and mortality
NET
NETs
neutrophil
neutrophil activation
Neutrophil extracellular trap
Neutrophils
Pathogenesis
pathogenesis of COVID-19
Pathogens
Platelet
previous study
promote
prothrombotic
regulated
Research
role
SARS CoV-2
shown
Thromboinflammation
Thrombotic complications
White blood cell
[DOI] 10.3390/ijms22105368 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms22105368 PMC 바로가기 [Article Type] Review
The efficacy of N-Acetylcysteine in severe COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial
중증 COVID-19 환자에서 N-아세틸시스테인의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약
Letter
[키워드] 1:1
Acetylcysteine
Activation
Acute respiratory infection
addition
Admission
All participant
All participants
antioxidant effect
antioxidant effects
appearance
approved
Arm
assigned
Bandar Abba
Bandar Abbas
baseline
Blinding
block randomization
Care
caused
cell damage
clinical
clinical condition
clinical trial
clinical trials
Committee
comparator
Comparator group
composite endpoint
control group
Controlled clinical trial
COVID-19
discharge
dissemination
dose
Effects
Efficacy
element
ethics committee
evaluate
excluded
expected
FIVE
Health
Health care
help
Hospitalization
hypersensitivity
Hypoxemia
infiltration
inflammatory factors
injection
intensive care
intensive care unit
Intervention
intervention group
Intravenous injection
investigator
Lactate
lactate dehydrogenase
LDH
lead
Local
lung
lung failure
lymphopenia
mechanical ventilation
Medical Science
Medical Sciences
medication
minute
N-acetylcysteine
number
objective
outcome
oxygen
oxygen partial pressure
parallel-group
partial pressure
participant
Patient
patients
Pharmaceutical Company
Phase 3
Placebo
positive PCR test
Pregnancy
primary endpoint
principal investigator
Progressive
protocol
random
randomised
randomised controlled trial
randomization
Randomized
Randomly
reactive oxygen species
receive
recruitment
Registered
registry
reported
respiration rate
respiratory infection
Saline
Sample size
SARI
SARS-CoV-2 virus
sequence
severe COVID-19
severe COVID-19 patient
severe COVID-19 patients
Side effect
Standard
Standard of care
Sterile
sterile water
Study protocol
supplementary material
technology
test results
the ethics committee
the patient
the SARS-CoV-2 virus
Treatment
Trial registration
university
water
water for injection
website
were measured
written consent
[DOI] 10.1186/s13063-021-05242-4 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-021-05242-4 PMC 바로가기 [Article Type] Letter
Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein
내피 세포 손상은 COVID-19의 중심 부분이며 스파이크 단백질의 S1 서브유닛을 주입하여 유도된 마우스 모델
Article
[키워드] ACE2
Analysis
Autopsy
Behavior
Brain
Brain tissues
C5b-9
caspase
caspase 3
caspase-3
cell damage
Complication
COVID-19
demonstrated
detect
diagnostic
died
endothelial
Endothelial cell
endothelial cell damage
endothelial damage
envelope
eosin
examined
fatal COVID-19
full length
hematoxylin
Hematoxylin and eosin
host response
IL6
immunohistochemistry
increased thirst
incubated
injected
injection
Localization
membrane protein
Membrane proteins
MFSD2a
mice
neurologic
neurologic signs
Neuron
neuronal
neuronal cell
neuronal cells
NOS
pathologist
pathology
positive
Protein
Proteins
pseudovirion
pseudovirions
S1 subunit
S2 subunit
SARS-CoV-2
SARS-CoV-2 protein
SARS-CoV-2 proteins
SARS-CoV2
SHIP1
spike
Spike protein
subunit
subunits
symptomatic
symptomatic COVID-19
tail
the S1 subunit
the spike protein
tissue
TNFα
Viral RNA
were used
wild type
[DOI] 10.1016/j.anndiagpath.2020.151682 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.anndiagpath.2020.151682 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection and Disease Modelling Using Stem Cell Technology and Organoids
줄기 세포 기술 및 오르가노이드를 사용한 SARS-CoV-2 감염 및 질병 모델링
Review
[키워드] ACE2
airway epithelial cells
alveolar
Apoptosis
cardiovascular system
Cell
cell damage
cells
Central nervous system
Choroid plexus
Clinical studies
clinical study
colonic
contribute
demonstrated
Direct
disease
Endothelial cell
endothelial cells
Enterocyte
enterocytes
epithelial
epithelial cells
gastrointestinal tract
highlighting
human host
Hypothesis
immunological
impairing
in vitro model
indirect effect
indirect effects
infect
infected individuals
Inflammation
innate immune response
intestinal organoid
lung
lung alveolar
lung epithelia
mechanism
Neurological symptom
Neurological symptoms
Neuron
neurons
Organoid
organoids
organs
Pathogenesis
pathogenesis of SARS-CoV-2
replicate
review
SARS-CoV-2
SARS-CoV-2 cell
SARS-COV-2 infection
SARS-CoV-2 pathogenesis
STEM
stem cell
surfactant
susceptible
systemic inflammatory
target
technology
Trigger
triggers
tropism
type I
variance
Vascular damage
Viral
viral damage
viral infection
virus
[DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
Therapeutic Potential of Mesenchymal Stem Cells and Their Products in Lung Diseases—Intravenous Administration versus Inhalation
Review
[키워드] acute respiratory distress
acute respiratory distress syndrome
acute respiratory syndrome
addressed
administration
caused
cell damage
cohorts
coronavirus
COVID-19
decrease
extracellular vesicle
Extracellular vesicles
extracorporeal membrane oxygenation
feasible
heterogeneity
Infection
inhalation
inhalation treatment
inhalers
Intravenous injection
intravenous treatment
lack
limitation
Lung disease
Lung diseases
Major
Mesenchymal stem cells
MSC
MSCs
Non-invasive
Potential
Prevent
product
repeated
respiratory diseases
SARS-CoV-2
STEM
stem cell
Stress
syndrome
target cell
the patient
therapeutic use
thrombus formation
Treatment
Treatment protocol
vasculature
[DOI] 10.3390/pharmaceutics13020232 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/pharmaceutics13020232 PMC 바로가기 [Article Type] Review
Can COVID-19 Cause Flare-Ups of Acute Hepatitis B? An Atypical Presentation of COVID-19 with Acute Hepatitis B
Case Report
[키워드] addition
Admission
ambulance service
Ammonium
Antigen
Apoptosis
blood test
Brain
Can
cause
caused
cell damage
chest X-ray
Coagulation
cough
COVID-19
COVID-19 patients
creatinine
cytotoxic T lymphocyte
Department
died
edema
elevated
Emergency
event
febrile
Fever
fixed
hepatitis B
hepatocyte
Infection
initial
innate immune system
liver
Liver damage
lung infiltrates
lung involvement
male
Necrosis
occurred
past medical history
Pathogenesis
pathophysiological
Patient
PCR testing
positive
presentation
Pupils
SARS-CoV-2
serological test
serology
Support
Swab
the patient
transaminases
urea
viral replication
X-ray
[DOI] 10.1155/2021/8818678 PMC 바로가기 [Article Type] Case Report
[DOI] 10.1155/2021/8818678 PMC 바로가기 [Article Type] Case Report
The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
Research article
[키워드] activities
acute lung injury
administration
analysis of variance
ANOVAanalysis of variance
average steady-state plasma concentration
baicalein
BALFbronchoalveolar lavage fluid
Body weight loss
Bronchoalveolar lavage fluid
Cavgaverage steady-state plasma concentration
CC50half-cytotoxic concentration
cell damage
Cmaxpeak plasma concentration
Concentration
Coronavirus disease 2019
COVID-19
COVID-19coronavirus disease 2019
CPEcytopathic effect
Cytopathic effect
dengue virus
DENVdengue virus
EC50half-maximal effective concentrations
EEPend-expiratory pause
effective
Effects
end-expiratory pause
enhanced pause
H & EHematoxylin and eosin
hACE2
hACE2human angiotensin-converting enzyme 2
half-cytotoxic concentration
half-maximal effective concentrations
Hematoxylin and eosin
HIVhuman immunodeficiency virus
Human angiotensin-converting enzyme 2
Human immunodeficiency virus
IL-1β
in vitro
in vivo
infected with SARS-CoV-2
inflammatory cell infiltration
inhibit
inhibited
Injury
Japanese encephalitis virus
JEVJapanese encephalitis virus
lesion
LLOQLower Limit of Quantitation
Lower Limit of Quantitation
lung
lung tissue
main protease
mice
MOImultiplicity of infection
morphology
Mpromain protease
multiplicity of infection
peak expiratory flow
peak plasma concentration
PEFpeak expiratory flow
Penhenhanced pause
pharmacological
reached
Replication
Respiratory function
Result
SARS-CoV-2
SARS-CoV-2severe acute respiratory syndrome coronavirus 2
Scutellaria baicalensis
selection index
serum
severe acute respiratory syndrome coronavirus 2
significantly
SIselection index
therapeutic drug
therapeutic effect
TNF-α
transgenic mice
Treatment
Vero E6 cell
virus
was performed
Zika virus
ZIKVZika virus
[DOI] 10.1016/j.bcp.2020.114302 [Article Type] Research article
[DOI] 10.1016/j.bcp.2020.114302 [Article Type] Research article
Endothelial Damage in Acute Respiratory Distress Syndrome
Review
[키워드] Activation
acute respiratory distress
ARDS
Biomarker
Biomarkers
blood vessel
cell damage
Coagulation
Coagulation system
Coronavirus disease-19
COVID-19
damage
dysfunction
effective
endothelial
Endothelial cell
endothelial damage
Endothelial dysfunction
endothelial injury
endotheliopathy
homoeostasis
hospitalised patient
Inflammation
involved
lung
morbidity and mortality
MOST
Pathogenesis
pathology
pharmacological treatment
Prognosis
Pulmonary endothelium
respiratory
Sepsis
syndrome
tested
Therapies
[DOI] 10.3390/ijms21228793 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms21228793 PMC 바로가기 [Article Type] Review
Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics
급성호흡곤란증후군의 간엽줄기세포치료제: 기초부터 임상까지
Review
[키워드] 2019 novel coronavirus
2019 novel coronavirus disease
acute respiratory distress
acute respiratory distress syndrome
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
alveolar fluid clearance
anti-apoptotic
Anti-inflammatory
approaches
ARDS
Bacterial
breath
caused
Cell
cell damage
Cell therapy
China
clinical study
clinics
coronavirus
coronavirus disease
COVID-19
COVID-19 patient
develop
disease
disrupt
distal
Effects
Efficacy
ENhance
epithelial
epithelial cell
event
Extracellular vesicles
Factor
high mortality
intrinsic
limit
lung
mechanism
mesenchymal stem cell
Mesenchymal stem cells
morbidity
MSC
MSC therapy
multiple organ failure
Novel coronavirus
novel coronavirus disease
occurred
optimization
Organ failure
organ injury
paracrine
pathophysiological
patients with ARDS
Pneumonia
promote
pulmonary endothelial
respiratory
respiratory distress
SARS-CoV-2
SARS-CoV-2-infected patient
SARS-CoV-2-infected patients
severe acute respiratory syndrome Coronavirus
severe pneumonia
stem cell
supportive care
survival
syndrome
therapeutic
therapy
variety
[DOI] 10.1007/s13238-020-00738-2 PMC 바로가기 [Article Type] Review
[DOI] 10.1007/s13238-020-00738-2 PMC 바로가기 [Article Type] Review