Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection폐 공간 프로파일링은 치명적인 SARS-CoV-2 감염이 있는 COPD 환자의 T 세포 서명을 나타냅니다Article Published on 2022-06-072022-09-11 Journal: Cells [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] airways Antigen CD4 CD45 CD45RO Cell characterized chronic obstructive chronic obstructive pulmonary disease chronic obstructive pulmonary disease (COPD) chronic obstructive pulmonary disease (COPD). COPD COVID-19 COVID-19 infection death died downregulation expression Gene Expression immune microenvironment immune response invasive lung Lung disease Lung diseases lung parenchyma memory memory T memory T cell obstructive pulmonary disease parenchyma Patient patients priming Profiling Protein proteomic pulmonary disease receptor ROI ROIs SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 disease 2019 SARS-CoV-2 entry SARS-COV-2 infection sick signature significant enrichment Smokers Still structural gene T cell T cell response T cells T-lymphocyte T-lymphocytes transcriptomic underlie vessel vessels with COVID-19 [DOI] 10.3390/cells11121864 PMC 바로가기 [Article Type] Article
Subclinical myocardial injury, coagulopathy, and inflammation in COVID-19: A meta-analysis of 41,013 hospitalized patientsResearch article Published on 2022-06-012022-10-05 Journal: IJC Heart & Vasculature [Category] 바이오마커, [키워드] article articles association benefit Biomarker BNP Cancer chronic obstructive CINAHL co-morbidity Coagulation Coagulopathy Complication complications of COVID-19 confidence Coronary artery disease COVID-19 D-dimer level death diabetes Effect Elevation estimate Evidence evidenced hazard hospitalized patient hospitalized patients hypertension implication increase increases in Inflammation interval invasive investigated marker Meta-analysis Myocardial myocardial injury NT-proBNP objective Odds ratio outcome Patient patients patients hospitalized performed Prevalence proportion pulmonary disease random-effects model Ratio reported Result risk stratification SARS-CoV-2 severe COVID-19 significantly specific biomarker Subclinical the disease the SARS-CoV-2 virus troponin Web of Science with COVID-19 [DOI] 10.1016/j.ijcha.2021.100950 [Article Type] Research article
A risk score for predicting death in COVID-19 in-hospital infection: A Brazilian single-center studyCOVID-19 병원 내 감염 사망 예측 위험 점수: 브라질 단일 센터 연구Article Published on 2022-06-012022-09-11 Journal: Journal of clinical ultrasound : JCU [Category] MERS, 바이오마커, [키워드] 95% CI age analyzed Arterial hypertension AUC Biomarker Biomarkers Brazil C-reactive protein Chest chronic obstructive chronic obstructive pulmonary disease collected Complete concerning consecutive patient consecutive patients correlated COVID-19 D dimer death death in COVID-19 diabetes Echocardiogram echocardiographic findings equation events Hospitalized hypertension In-hospital in-hospital mortality in-hospital patient in-hospital patients information intubation mechanical ventilation men Mortality multiple logistic regression novel obstructive pulmonary disease occurred Patient patients performed predict Probability Prospective Study pulmonary disease risk Risk factors ROC ROC Curve single-center study systemic arterial hypertension Thoracic variable with COVID-19 [DOI] 10.1002/jcu.23195 PMC 바로가기 [Article Type] Article
A causal learning framework for the analysis and interpretation of COVID-19 clinical dataCOVID-19 임상 데이터의 분석 및 해석을 위한 인과 학습 프레임워크Review Published on 2022-05-192022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] Accuracy age Analysis analyzed approach Bayesian binary BSL cause chronic obstructive Clinical data Clinical practice connection contribute COVID-19 dataset decision disease evaluate Features hospital Hospital admission Inclusion increase information Interpretation knowledge learning outcome PaO2/FiO2 ratio Patient Predictive provide pulmonary disease recognize robust routine blood test Structure subject the disease tree [DOI] 10.1371/journal.pone.0268327 PMC 바로가기 [Article Type] Review
Shared genomic architectures of COVID-19 and antisocial behaviorCOVID-19의 공유 게놈 구조와 반사회적 행동Article Published on 2022-05-102022-09-11 Journal: Translational Psychiatry [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggression antisocial antisocial behavior average average income baby calculate cause chronic obstructive chronic obstructive pulmonary disease coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 Diseases estimate exposure to false-discovery rate Genetic genetics Genome-wide association studies Genome-wide association study genomic Health higher risk Linkage disequilibrium matrix measure mind obstructive pulmonary disease omicron overlap pandemic pulmonary disease SARS-CoV-2 severe acute respiratory syndrome Coronavirus text traits Vaccine variant verbal with COVID-19 [DOI] 10.1038/s41398-022-01948-4 PMC 바로가기 [Article Type] Article
Survival analysis of COVID-19 patients in Ethiopia: A hospital-based studyObservational Study Published on 2022-05-092022-10-05 Journal: PLoS ONE [Category] 임상, [키워드] Admission admitted to ICU age analyzed Care carried chronic chronic kidney diseases chronic obstructive Clinical characteristics close monitoring confidence COVID-19 COVID-19 case COVID-19 disease COVID-19 patient Cox regression analysis death deaths Final global public health hazard high mortality higher risk HIV/AIDS Hospitalization Hospitalized hospitalized patient independent risk factor interval intranasal Kidney disease laboratory-confirmed majority median medical record Mortality mortality rate nine Observational cohort study occurred Older oxygen Patient patients hospitalized performed predictor Probability pulmonary disease Ratio retrospective risk risk of death Sociodemographic survival survival analysis the patient those with comorbidity treated Treatment zone [DOI] 10.1371/journal.pone.0268280 PMC 바로가기 [Article Type] Observational Study
Clinical course and outcomes of COVID-19 patients with chronic obstructive pulmonary disease: A retrospective observational study in Wuhan, ChinaObservational Study Published on 2022-05-062022-10-05 Journal: Medicine [Category] 임상, [키워드] acute exacerbation Admission age age and sex Analysis analyzed China chronic obstructive clinical Clinical course Clinical outcome clinical outcomes Comorbidity COPD coronavirus disease correlated Course COVID-19 COVID-19 patient Cox regression death diagnosis of COVID-19 Dyspnea exhibited Hospitalization Huoshenshan Hospital Infection Inflammation Inflammatory responses Injury intensive care Kaplan-Meier Laboratory test mechanical ventilation outcome pathophysiology Patient performed proportion pulmonary disease Randomly regression analysis Respiratory failure respiratory tract retrospective Retrospective study selected severe COVID-19 subsequent two groups viral clearance was performed Wuhan Wuhan, China [DOI] 10.1097/MD.0000000000029141 PMC 바로가기 [Article Type] Observational Study
Cross-sectional study of pain-related variables before and during the COVID-19 pandemic in patients with COPDResearch article Published on 2022-05-012022-10-05 Journal: Pain management nursing : official journal of the [Category] 진단, [키워드] accompanied Anxiety case-control study chronic obstructive contribute COPD COVID-19 diagnosis COVID-19 pandemic cross-sectional cross-sectional study Depression evaluated Health status influence intensity outcome Pain pandemic Patient patients Prevalence Psychological pulmonary disease Result sensitivity statistical difference variable worsening [DOI] 10.1016/j.pmn.2022.05.001 [Article Type] Research article
Inhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19Research article Published on 2022-04-012022-10-05 Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids [Category] 치료법, [키워드] acute lung inflammation acute respiratory distress Administered alveolar Anti-inflammatory Antithrombotic Asthma Budesonide cannabidiol chronic obstructive COPD COVID-19 cytokine determine distress docosahexaenoic acid (DHA) Docosapentaenoic acid (DPA) effective Effects Eicosapentaenoic acid (EPA) Fatty acid free fatty acid group groups histology IL-10 IL-1β IL-6 inhalation injection intravenous investigated less LPS lung cancer lung disorders Lung inflammation male mitigate Montelukast nebulized no evidence of omega-3 Omega-3 fatty acids Pneumonia preclinical data pulmonary disease Severity Score Side effects TGF-β the disease thrombosis TNF-α treated Treatment triggered [DOI] 10.1016/j.plefa.2022.102426 [Article Type] Research article
Vaccination status among patients with the need for emergency hospitalizations related to COVID-19코로나19 관련 긴급 입원이 필요한 환자의 예방접종 현황Article Published on 2022-04-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval age Alpha Alpha variant Analysis Characteristics chronic obstructive chronic obstructive pulmonary disease Comorbidities Comorbidity CoronaVac COVID-19 COVID-19 patients COVID-19 vaccines curiosity Delta delta variant diabetes Diabetes Mellitus died disease dose Efficacy Emergency emergency department emergency medicine emergency room Emergency use evaluate Factor Gender Hospitalization hospitalizations hypertension intensive care intensive care unit intervals lower mortality male matter moderate Mortality mortality rates multivariate logistic regression multivariate logistic regression analysis obstructive pulmonary disease Odds ratio Older other variant other variants Patient patients hospitalized performed Pfizer-BioNTech pulmonary disease reduce Regression analyses Retrospective study rRT-PCR SARS-COV-2 infection severe COVID-19 significantly significantly higher the patient the vaccine thought vaccination Vaccination Status Vaccine vaccine efficacy variant was performed women [DOI] 10.1016/j.ajem.2022.01.067 PMC 바로가기 [Article Type] Article