COVID-19 prognostic modeling using CT radiomic features and machine learning algorithms: Analysis of a multi-institutional dataset of 14,339 patientsResearch article Published on 2022-06-012022-10-05 Journal: Computers in biology and medicine [Category] 바이오마커, [키워드] Algorithm ANOVA AUC automatically can be used characteristic Classifier classifiers clinical setting Combination COVID-19 COVID-19 patients dataset datasets evaluated feature Features forest heterogeneous highest intensity lung machine learning Patient performed positive Positive test predictive power Prognosis prognostic Radiomics relief reported Result robust RT-PCR sensitivity Sensitivity and specificity Seven specificity splitting statistically significant test dataset X-ray CT [DOI] 10.1016/j.compbiomed.2022.105467 [Article Type] Research article
Fibronectin as a Marker of Disease Severity in Critically Ill COVID-19 Patients중환자 COVID-19 환자의 질병 중증도 지표로서의 피브로넥틴Article Published on 2022-05-062022-09-11 Journal: Cells [Category] Coronavirus, COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] Alter APACHE II Bacterial Bacterial sepsis Biomarker Biomarkers can be used cellular clinical setting clinical settings correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 sample COVID-19 samples Critically ill Critically ill patient critically ill patients disease severity ELISA etiology expression of gene Extracellular matrix Fibronectin form help Ill immune response immunoblotting Infection Intensive intensive care intensive care unit knowledge MONITOR Mortality mortality prediction no significant difference no significant differences Non-survivors outcomes Patient plasma predict Proteins proteolytic Research SARS-CoV-2 virus Sepsis significantly higher SOFA scores treated Treatment Treatment outcome Viral was related were measured [DOI] 10.3390/cells11091566 PMC 바로가기 [Article Type] Article
Delineating the impact of COVID-19 on antimicrobial resistance: An Indian perspectiveCOVID-19가 항균제 내성에 미치는 영향 묘사: 인도의 관점Review Published on 2022-04-202022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] AMR antimicrobial Antimicrobial manufacturing waste Antimicrobial residues antimicrobial resistance Antimicrobials clinical setting clinical settings COVID-19 COVID-19 pandemic driving drug Empirical consumption. Escalation excessive use fear greater hygiene product Impact impacted India outcome pandemic Perspective Practice Prevalence provide public health repurposing Research SARS-CoV-2 Secondary infection secondary infections Self-medication Treatment variants variants of concern [DOI] 10.1016/j.scitotenv.2021.151702 PMC 바로가기 [Article Type] Review
Evaluation of SARS-CoV-2 antibody point of care devices in the laboratory and clinical setting실험실 및 임상 환경에서 SARS-CoV-2 항체 현장 진료 장치 평가Article Published on 2022-03-312022-09-11 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody test antibody tests can not capillary blood Chain Reaction change Characteristics clinical setting clinical utility Cohort collected Control correlated days post infection declined determine diagnose evaluated Evidence General population high neutralising antibody Immune status implication independent Infection Laboratory lack neutralising antibody onset of symptoms participant peaked performed POC point of care polymerase chain polymerase chain reaction positive real-time polymerase chain reaction reported RT-PCR SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody tests SARS-COV-2 infection SARS-CoV-2 virus sensitivity serum serum sample serum samples specificity Study participants the SARS-CoV-2 virus titres utility was measured were used [DOI] 10.1371/journal.pone.0266086 PMC 바로가기 [Article Type] Article
Recombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patientsResearch Published on 2022-03-052022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] administration Admission alteration alterations approaches Bacterial sepsis Blood Cell cell proliferation characteristic clinical setting collected COVID-19 COVID-19 patient COVID-19 patients Critically ill Critically ill patient CTLA-4 described evaluated Ex vivo Exhaustion expression feature flow cytometry hallmark Hospitalized ICU ICU admission ICU patient IFN-γ immune immunostimulation inhibited intensive care interleukin-7 lymphopenic marker mononuclear cell over-expression pathophysiology Pathways Patient PD-L1 peripheral proliferation recombinant Result reversed SARS-CoV-2 Sepsis severe coronavirus disease severe COVID-19 severe COVID-19 patient significantly supplementary material T cell T cell activation T cell proliferation T lymphocyte T lymphocyte response T lymphocytes therapeutic therapeutic strategy therapy transcriptomic profile treat [DOI] 10.1186/s13613-022-00982-1 PMC 바로가기 [Article Type] Research
Insights into the immune responses of SARS-CoV-2 in relation to COVID-19 vaccinesCOVID-19 백신과 관련된 SARS-CoV-2의 면역 반응에 대한 통찰력Review Published on 2022-03-012022-09-11 Journal: Journal of microbiology (Seoul, Korea) [Category] SARS, 변종, [키워드] Ad26.COV2.S adverse effects antigenic variants applied approved benefit BNT162b2 candidate caused ChAdOx1 ChAdOx1 nCoV-19 clinical setting clinical settings commercialization coronavirus disease Coronavirus disease 2019 COV2.S COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccinations COVID-19 vaccine Effect Health Organization immune immune response immune responses immunological immunologically Inactivated Vaccines insight manifestation Manifestations mRNA mRNA vaccines mRNA-1273 nCoV reported required SARS-CoV-2 Vaccinations Vaccine Vaccine development Vaccines virus infection with COVID-19 World Health Organization [DOI] 10.1007/s12275-022-1598-x PMC 바로가기 [Article Type] Review
The Comparability of Anti-Spike SARS-CoV-2 Antibody Tests is Time-Dependent: a Prospective Observational StudyAnti-Spike SARS-CoV-2 항체 검사의 비교 가능성은 시간에 따라 달라집니다: 전향적 관찰 연구Observational Study Published on 2022-02-232022-09-12 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Abbott agreement antibody Antibody assays antibody levels Antibody test antibody tests AZD1222 binding antibody Blood blood collection booster changed clinical setting clinical settings clinician comparability correlation dependent on evaluated first dose greater homologous Initially International international standard Neutralization assay observational study participant Prospective prospective observational study provided quantified Quantitative Roche SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antibody test SARS-CoV-2 antibody tests second dose serology significantly Standardization Test the timing time-dependency vaccination Withdrawal [DOI] 10.1128/spectrum.01402-21 PMC 바로가기 [Article Type] Observational Study
Length of Stay Analysis of COVID-19 Hospitalizations Using a Count Regression Model and Quantile Regression: A Study in Bologna, ItalyArticle Published on 2022-02-162022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] adopted Affect age AIC analyses average being Characteristics clinical setting count count data model covariate COVID patient COVID-19 COVID-19 patient criteria criterion Effect Factor First wave form functions Generalized linear model group help heterogeneity hospital Hospital admission Hospitalization Hospitalized hospitals Hurdle model ICU identify information intensive care unit Italy Length Length of stay Model Poisson Poisson distribution potential risk predictor provided Quantile quantile regression Regression Regression model response variable risk factor Rootograms second wave significant changes in significantly statistical statistically significant Vuong test [DOI] 10.3390/ijerph19042224 PMC 바로가기 [Article Type] Article
WhatsApp-Delivered Intervention for Continued Learning for Nurses in Pakistan During the COVID-19 Pandemic: Results of a Randomized-Controlled TrialRandomized Controlled Trial Published on 2022-02-152022-10-04 Journal: Frontiers in Public Health [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] Analysis clinical setting control group Corona coronavirus COVID-19 COVID-19 pandemic Digital Diseases Effectiveness healthcare highlight infection control Infection prevention Intervention intervention group learning maintain management medium Nurse online-based patient safety physical distancing Practitioner professional Result reveal SARS-CoV-2 significantly Support [DOI] 10.3389/fpubh.2022.739761 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Use of Wearable Pulse Oximeters in the Prompt Detection of Hypoxemia and During Movement: Diagnostic Accuracy Study저산소혈증의 즉각적인 감지 및 운동 중 착용형 맥박산소 측정기의 사용: 진단 정확도 연구Original Paper Published on 2022-02-152022-09-10 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Accuracy adjusted analyzed arterial blood arterial blood oxygen saturation blood oxygen Blood oxygen saturation calculate Care characteristic Clinical deterioration clinical setting comparable continuous monitoring COVID-19 disease detect detection Deterioration Diagnostic accuracy disease estimate evaluated hospital Hypoxemia hypoxia Identifier Isolation ISRCTN registry mHealth motion objective organization oximeter oxygen oxygen saturation Participants Patient patient monitoring patients with COVID-19 performance peripheral peripheral oxygen saturation Philip physiological pulse Pulse oximeter Pulse Oximeters receiver operating characteristic receiver operating characteristic curve receiving Registration reliability report required Result risk root rubbing sensitivity specificity Support Tablet Tapping was used Wavelet wearable pulse oximeter wearable technology [DOI] 10.2196/28890 PMC 바로가기 [Article Type] Original Paper