Prevalence of post-COVID-19 in patients with fibromyalgia: a comparative study with other inflammatory and autoimmune rheumatic diseasesObservational Study Published on 2022-05-192022-10-05 Journal: BMC Musculoskeletal Disorders [Category] 임상, [키워드] ACR acute infection antibody Antigen Autoimmune Characteristics Cognitive impairment collected college Combined COVID-19 COVID-19 diagnosis criteria determine Diagnosis Diseases emotional Factor fatigue fibromyalgia group had more Hospital admission impairment index Inflammatory Long Long COVID-19 Loss of Smell number of symptom Patient patients physical Pneumonia polymerase chain positive Post Covid-19 Prevalence rheumatic disease Rheumatic diseases severity Symptom Symptoms total score [DOI] 10.1186/s12891-022-05436-0 PMC 바로가기 [Article Type] Observational Study
Optimal Drug Regimen and Combined Drug Therapy and Its Efficacy in the Treatment of COVID-19: A Within-Host Modeling Study최적의 약물 요법과 복합 약물 요법과 COVID-19 치료의 효능: 숙주 내 모델링 연구Article Published on 2022-05-192022-09-11 Journal: Acta biotheoretica [Category] COVID19(2023년), SARS, 치료제, [키워드] Administered administration Arbidol average basic reproduction number Cell Combination combination therapies combination therapy Combined Comparative Comparative effectiveness study COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 pathogenesis death drug Drug interventions drugs Effectiveness Efficacy help include infected cells infection-related mortality Inflammatory mediators interferon Intervention life-threatening Lopinavir Lopinavir/ritonavir mathematical medical intervention modeling number of infected Optimal control problem Optimal drug Regimen physician reduce regimen Remdesivir Ritonavir significantly Stage susceptible cell Treatment treatment of COVID-19 Viral load were used [DOI] 10.1007/s10441-022-09440-8 PMC 바로가기 [Article Type] Article
Combined kinetic analysis of SARS-CoV-2 RNAemia, N-antigenemia and virus-specific antibodies in critically ill adult COVID-19 patients중증 성인 COVID-19 환자의 SARS-CoV-2 RNA혈증, N-항원혈증 및 바이러스 특이 항체의 결합 운동 분석Article Published on 2022-05-182022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] adult COVID-19 patient analyses Analysis antibody Antibody detection antigenemia bloodstream CAST Cohort collected Combined component COVID-19 patient COVID-19 patients Critically ill decreasing detection rate dissemination examined Free help immunoassays immunochromatography inverse correlation kinetic analysis lateral flow median median age median time nucleocapsid onset of symptoms patients performed plasma RBD Receptor binding domain respiratory RNA RT-PCR assay SARS-CoV-2 SARS-CoV-2-RBD specific antibodies specimen symptoms onset upper respiratory tract Viral Viral load virus virus clearance virus-specific antibodies [DOI] 10.1038/s41598-022-12461-5 PMC 바로가기 [Article Type] Article
Pasteurization, storage conditions and viral concentration methods influence RT-qPCR detection of SARS-CoV-2 RNA in wastewater저온 살균, 보관 조건 및 바이러스 농도 방법은 폐수에서 SARS-CoV-2 RNA의 RT-qPCR 검출에 영향을 미칩니다.Article Published on 2022-05-152022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect approach centrifugation collected Combined Community complementary Concentration coronavirus COVID-19 COVID-19 pandemic decrease demonstrated fecal FIVE glycol infected individual infected individuals Local Mild MONITOR N gene NaCl parameter pasteurization pellet plant polyethylene Polyethylene glycol Population size public health purification qPCR recommendation reduction RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 N gene SARS-CoV-2 RNA SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus storage condition student Surveillance t-test temperature the SARS-CoV-2 the SARS-CoV-2 virus total RNA Treatment variety viral particle Viral particles Viral RNA Viral RNA concentration virus Volume wastewater [DOI] 10.1016/j.scitotenv.2022.153228 PMC 바로가기 [Article Type] Article
Higher incidence of novel coronavirus (COVID-19) cases in areas with combined sewer systems, heavy precipitation, and high percentages of impervious surfaces하수도, 집중호우, 불투수면 비율이 높은 지역에서 신종 코로나바이러스(COVID-19) 사례 발생률이 높음Article Published on 2022-05-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] Aerosols association Climate change Combination Combined combined sewer Combined sewer overflow (CSO) Combined sewer system (CSS) confounder COVID-19 COVID-19 case COVID-19 cases COVID-19 incidence COVID-19 patient CSS droplets events Evidence example feces Frequency Impervious surfaces in urine incidence incidence rate Inconclusive increase in ingestion inhalation Interaction investigated management Novel coronavirus observé P-value percentage population density Precipitation Precipitation. Regression model released reservoir reveal SARS-CoV-2 severity stormwater Transport urbanization Urine variable wastewater water [DOI] 10.1016/j.scitotenv.2022.153227 PMC 바로가기 [Article Type] Article
Use of combined treatment of 3rd-generation cephalosporin, azithromycin and antiviral agents on moderate SARs-CoV-2 patients in South Korea: A retrospective cohort study한국에서 중등도 SARs-CoV-2 환자에 대한 3세대 세팔로스포린, 아지트로마이신 및 항바이러스제 병용 치료: 후향적 코호트 연구Article Published on 2022-05-042022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료제, [키워드] adjust administration adverse event Analysis analyzed Antibiotics antiviral agent Antiviral agents association Azithromycin baseline characteristics cephalosporin Clinical outcome Cohort cohorts Combined combined treatment conducted confounding factors COVID-19 COVID-19 patient Cox regression analysis Cox regression method death Efficacy and safety Endpoint endpoints Evidence groups hazard ratio hazard ratios Hospital stay Hydroxychloroquine inclusion criteria Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves laboratory-confirmed Lopinavir Lopinavir/ritonavir low-dose mild to moderate Mild to moderate COVID-19 moderate Moderate COVID-19 moderate COVID-19 patients no significant difference no significant differences not significant Patient performed Prevent Propensity score propensity score matching PSM retrospective cohort study Ritonavir SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients significant differences South South Korea Standard standard supportive care statistical significance Supportive treatment symptom resolution Time to symptom resolution Treatment treatment arm treatment group viral clearance were used [DOI] 10.1371/journal.pone.0267645 PMC 바로가기 [Article Type] Article
Genetic Landscape of the ACE2 Coronavirus ReceptorACE2 코로나바이러스 수용체의 유전적 지형Meta-Analysis Published on 2022-05-032022-09-11 Journal: Circulation [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] ACE2 ACE2 protein Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biological systems blood immune cells cardiometabolic cardiovascular disease cardiovascular diseases cardiovascular diseases. Cell cell type circulating Clinical studies clinical study Combined complex complex disease conducted coronavirus correlated correlation COVID-19 COVID-19 severity cross-sectional Diseases DNA methylation elevated epidemiological epigenomic expressed functional gastrointestinal tracts Genetic genetic architecture Genome genome-wide association Genome-wide association study heart heritability Hospitalization Human human cell human cells immune cells in silico individual Infection landscape likelihood loci mapped medications mendelian randomization Meta-analysis Odds ratio outcome Phenotypes plasma Protein Quantitative randomization receptor Regulatory related diseases resource respiratory SARS-CoV-2 severe COVID-19 soluble ACE2 suggested tissue transcriptomic Treatment variant Vascular vascular disease vascular diseases [DOI] 10.1161/CIRCULATIONAHA.121.057888 PMC 바로가기 [Article Type] Meta-Analysis
Combined therapy of tocilizumab and corticosteroids in severe SARS-CoV-2 disease중증 SARS-CoV-2 질환에서 토실리주맙과 코르티코스테로이드의 병용 요법Case Reports Published on 2022-05-012022-09-12 Journal: Medicina intensiva [Category] COVID19(2023년), SARS, 진단, [키워드] Combined Corticosteroid disease severe SARS-CoV-2 therapy Tocilizumab [DOI] 10.1016/j.medine.2022.02.013 PMC 바로가기 [Article Type] Case Reports
Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafishSARS-CoV-2 스파이크 단백질의 비강 내 전달은 제브라피쉬에서 후각 손상, 염증 및 후각 기능 장애를 유발하기에 충분합니다Article Published on 2022-05-012022-09-11 Journal: Brain, behavior, and immunity [Category] COVID19(2023년), SARS, 치료기술, [키워드] animal animal models animals Anosmia bind cause Cell characterized cilia Cluster Combined damage Danio direct infection driven by edema endothelial EOG explained expression fish food functional hemorrhage hemorrhages Histopathology implication indicated Infection Inflammation Inflammatory response Inflammatory responses intranasal intranasally Loss of Smell mechanism myeloid cell nasal epithelium non-neuronal cell non-neuronal cells olfactory Olfactory damage olfactory dysfunction olfactory function Olfactory organ olfactory receptor Olfactory receptor expression organ prevalent Protein RBD receptor reduced response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S SARS-CoV-2 spike SARS-CoV-2 spike protein sensory neuron spike Spike protein Symptom treated Vaccine Viral protein Viral proteins widespread zebrafish Zebrafish (Danio rerio). [DOI] 10.1016/j.bbi.2022.03.006 PMC 바로가기 [Article Type] Article
Combined administration of inhaled DNase, baricitinib and tocilizumab as rescue treatment in COVID-19 patients with severe respiratory failure중증 호흡부전이 있는 COVID-19 환자의 구조 치료로서 흡입형 DNase, 바리시티닙 및 토실리주맙의 병용 투여Article Published on 2022-05-012022-09-12 Journal: Clinical immunology (Orlando, Fla.) [Category] Coronavirus, COVID19(2023년), SARS, 바이오마커, 임상, 진단, 치료법, [키워드] Administered administration analysed Baricitinib clinical observations Combined COVID-19 COVID-19 patient dissolve DNase duration of hospitalization fibroblasts Follow-up group hyperinflammation IL-1-receptor Immunomodulatory agent immunothrombosis in-hospital mortality Inhaled inhibited inhibitor intubation rate lung median monotherapy Neutrophil extracellular traps paO2/fiO2 pathway plasma randomized trial reduce mortality severe respiratory failure significantly Standard-of-care Support survival tissue Tissue Factor Tocilizumab Treatment [DOI] 10.1016/j.clim.2022.109016 PMC 바로가기 [Article Type] Article