Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled TrialArticle Published on 2022-09-162022-11-15 Journal: Nutrients [Category] SARS, 진단, [키워드] 25-hydroxyvitamin D 95% CI Acute respiratory infection adjusted hazard ratio antibody baseline blood sample BNT162b2 BNT162b2 Pfizer boost Breakthrough SARS-CoV-2 infection cellular response ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 Oxford–AstraZeneca circulating collected Concentration concentrations Controlled deficiency determine dose dried blood spot Effect Efficacy elevated Follow-up IFN-γ IgA IgG IgM influence interferon interferon gamma investigated mean difference neutralising antibody neutralising antibody titre of BNT162b2 offer participant Pfizer Protective randomised controlled randomised controlled trial reported response risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly supernatant titre titres vaccination venous Vitamin Vitamin D Vitamin D status vitamin D supplement Vitamin D supplementation Whole blood [DOI] 10.3390/nu14183821 PMC 바로가기
The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral ActivityArticle Published on 2022-09-132022-11-15 Journal: Viruses [Category] SARS, 치료제, [키워드] accompanied activity affected antiviral activity bovine Bovine seminal plasma Cell component components concentrations COVID-19 Cytokines cytotoxicity demonstrated elements etiological agent experiment Fn-type 2 proteins function Glucose glycoprotein Growth factors impair Infection infections Infectious disease Influenza virus inhibit investigated limit lipids mammalian membrane fusion metabolites Particle PDC-109 plasma plasma protein Proteins reporter respiratory SARS-CoV-2 Seminal sexual transmission significantly spike treatment regimen viability viral infection virus virus inhibition virus particles VSV VSV replicon. without affecting [DOI] 10.3390/v14092031 PMC 바로가기
Coronavirus Vaccination: Spike Antibody Levels in Health Workers after Six Months-A Cross-Sectional StudyArticle Published on 2022-09-102022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, [키워드] Administered age Anti-spike antibody approved average blood sample booster chemiluminescent immunoassay concentrations COVID-19 criterion cross-sectional elapsed elevated Epidemics exclusion health worker healthcare worker high risk hospital immunoreactivity Immunosuppression Infection infection with SARS-CoV-2 investigated Level MOST mRNA nucleocapsid protein occupational health Pandemics participant Protective required SARS-CoV-2 SARS-CoV-2 pandemic second vaccination significantly spike vaccination Vaccine worker [DOI] 10.3390/ijerph191811422 PMC 바로가기
Quantifying the Relationship between SARS-CoV-2 Wastewater Concentrations and Building-Level COVID-19 Prevalence at an Isolation Residence: A Passive Sampling ApproachArticle Published on 2022-09-072022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, 치료제, [키워드] approach association baseline collected college campus monitoring complex concentrations correlated covariate COVID-19 demonstrated Epidemiology excreta fecal Fecal shedding help highlight individuals with COVID-19 Infection infections Isolation Laboratory maintain majority median MONITOR multivariable model N1 and N2 Passive Passive sampling polymerase chain positive correlation Prevalence processed public health Public health responses quantified Quantitative relationship remained RNA load RT-qPCR Sample sampling SARS-CoV-2 SARS-CoV-2 RNA specimen Surveillance susceptible the mean Variation Viral load viral shedding wastewater Wastewater-based epidemiology yielding [DOI] 10.3390/ijerph191811245 PMC 바로가기
Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central PennsylvaniaArticle Published on 2022-09-012022-11-16 Journal: Journal of environmental quality [Category] 치료기술, [키워드] acute respiratory syndrome affected analyzed Antibiotics Area authority calculated collected Concentration concentrations connection coronavirus COVID-19 pandemic Dexamethasone doxycycline effective explained facility FIVE Health highlight hospitalized patient Hydroxychloroquine Impact Medicine no correlation occurred pandemic patients with COVID-19 persistence plant plants powerful tool Quotient Reclamation Remdesivir returned reuse risk Sample state Surveillance therapeutic agent treated Treatment university utility Variation virus water with COVID-19 would increase [DOI] 10.1002/jeq2.20398 PMC 바로가기
Aerosol Generation During Otologic SurgeryObservational Study Published on 2022-09-012022-10-05 Journal: Otology & neurotology : official publication of th [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome aerosol Aerosol generation aerosol-generating procedures average Concentration concentrations coronavirus cough coughing ENhance Factor Generation help identify measure occur Operating room Otologic outcome Particle pathogen Pathogens Prospective Study quantified recorded reduce reduced required significantly higher Spread suction surgery to define Total was measured were recorded were used [DOI] 10.1097/MAO.0000000000003591 PMC 바로가기 [Article Type] Observational Study
Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2SARS-CoV-2 Omicron subvariants, BA.1 및 BA.2에 대한 중화 항체 및 항바이러스 약물의 다양한 효능Article Published on 2022-09-012022-09-11 Journal: Antiviral Research [Category] COVID19(2023년), SARS, 변종, 진단, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Analysis antibodies antibody Antiviral antiviral drug antiviral drugs Antiviral effect antiviral effects BA.1 BA.2 Casirivimab Cell culture concentrations conserved coronavirus Delta drug treatment Efficacy EIDD-1931 Evidence FIVE Gamma Imdevimab Infection intrinsic mathematical molnupiravir Neutralizing antibodies neutralizing antibody Nirmatrelvir omicron other variant other variants quantified replacing respiratory SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus Sotrovimab Spread Treatment variant variants Viral [DOI] 10.1016/j.antiviral.2022.105372 PMC 바로가기 [Article Type] Article
Impaired immunity and high attack rates caused by SARS-CoV-2 variants among vaccinated long-term care facility residentsArticle Published on 2022-09-012022-11-15 Journal: Immunity, Inflammation and Disease [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome addressed Alpha variant antibody attack rate B.1.1.7 B.1.351 Beta Breakthrough infection Care caused cell-mediated immune response Cell-mediated immunity concentrations coronavirus COVID-19 COVID-19 outbreak COVID-19 vaccination elderly HCWs healthcare worker high risk IgG Immunity Immunoglobulin Impaired investigated Long-term care Long-term care facility marker NAb titer Neutralizing antibodies neutralizing antibody outbreak protocols SARS-CoV-2 variant second dose severe coronavirus disease spike glycoprotein susceptible vaccination vaccine doses vaccine response Vaccine-induced immunity variant variants [DOI] 10.1002/iid3.679 PMC 바로가기
Importance of external quality assessment for SARS-CoV-2 antigen detection during the COVID-19 pandemicCOVID-19 전염병 동안 SARS-CoV-2 항원 검출을 위한 외부 품질 평가의 중요성Article Published on 2022-09-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome analysed Antigen antigen test antigen tests approval automated circulating Combination concentrations country COVID-19 COVID-19 pandemic COVID-19 testing dataset datasets Deletion evaluate False negative false negatives Genetic immunoassays Importance in viral inactivated increase in independent Laboratory Lateral mutant Panel participant point-of-care test Quality Quality assurance rapid antigen test Registered Regulatory reported required respiratory SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 variants sensitivity Severe acute respiratory syndrome shown strain Support Surveillance variants variants of concern Viral viral loads VOCs [DOI] 10.1016/j.jcv.2022.105222 PMC 바로가기 [Article Type] Article
Antiviral drugs against influenza: Treatment methods, environmental risk assessment and analytical determinationReview article Published on 2022-09-012022-10-05 Journal: Journal of environmental management [Category] 치료제, [키워드] addition Adsorption Antiviral antiviral drug Antiviral drugs against influenza approach biological processes Characteristics Coagulation Combined Concentration concentrations contaminant Contamination COVID-19 drug Ecotoxicological risk Effect Effects evaluated filtration indicated Influenza investigated metabolite metabolites over Perspective plant Prevent required Research risk tested Toxicity Treatment Wastewater treatment were assessed [DOI] 10.1016/j.jenvman.2022.115523 [Article Type] Review article