Mass Spectrometry and Structural Biology Techniques in the Studies on the Coronavirus-Receptor InteractionReview Published on 2020-09-102022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] ACE2 receptor protein acute respiratory syndrome Biology conformational changes coronavirus Cryo-electron microscopy described glycosylation human cell human protein Interaction interactions mass mass spectrometry MS Protein protein-protein interaction receptor S protein SARS Coronavirus SARS-CoV-2 Spectrometry spike protein-ACE2 interaction structural techniques technique the S protein three-dimensional structure X-ray crystallography [DOI] 10.3390/molecules25184133 PMC 바로가기 [Article Type] Review
The Challenges of Vaccine Development against Betacoronaviruses: Antibody Dependent Enhancement and Sendai Virus as a Possible Vaccine VectorReviews Published on 2020-09-042022-10-30 Journal: Molecular Biology [Category] COVID-19, [키워드] ADE Administered Amino acid Antibody-dependent enhancement antigenic Antiviral approach betacoronaviruses caused Cell-mediated immune responses challenge Combination conformational changes conservative antigenic determinants coronavirus COVID-19 Dependent determinant development effective elicit enhancement expressing glycosylation help humoral Immunity inactivated induce Infection intranasally MERS-CoV mucosal mucosal immune murine respirovirus new SARS-CoV-2 provide respiratory pathogen respiratory tract risk S-protein Safe SARS-CoV-1 SARS-CoV-2 Sendai virus stimulate targeting the spike protein the vaccine Trial Vaccine vaccine vector vector viral infection Viral protein viral vectors virion [DOI] 10.1134/S0026893320060151 PMC 바로가기 [Article Type] Reviews
Molecular dynamics approach to probe the antigenicity of PagN – an outer membrane protein of Salmonella TyphiArticle Published on 2018-06-302024-09-07 Journal: J Biomol Struct Dyn [Category] 살모넬라증, [키워드] conformational changes epitope extracellular loops pathogenicity islands principal component analysis PMC 바로가기