The Effects of Theory-Based Educational Intervention and WhatsApp Follow-up on Papanicolaou Smear Uptake Among Postnatal Women in Malaysia: Randomized Controlled TrialRandomized Controlled Trial Published on 2022-06-272022-10-05 Journal: JMIR mHealth and uHealth [Category] 임상, [키워드] analyzed assigned Attitude baseline both group Cancer changed clinical clinics Cluster conducted control group control groups Controlled COVID-19 pandemic demonstrated determine Effect effective Effectiveness Factors first stage Follow-up form Google Health health knowledge high uptake IBM Intervention intervention group intervention study investigated knowledge knowledge score Malaysia mortality rate multifactorial Negeri Sembilan Neoplasms p value Papanicolaou test participant Patient Population Practice previous study primary endpoint proportion Psychological psychological theory questionnaire Randomized controlled trial Randomly reduce registry researcher secondary endpoint Self-efficacy shown Significant single-blind smear social media SPSS standard care statistically significant tested theory uptake uterine uterine cervical neoplasms. was used WhatsApp withdrawn women [DOI] 10.2196/32089 PMC 바로가기 [Article Type] Randomized Controlled Trial
Neutralising reactivity against SARS-CoV-2 Delta and Omicron variants by vaccination and infection history백신 접종 및 감염 이력에 의한 SARS-CoV-2 Delta 및 Omicron 변이체에 대한 반응성 중화Article Published on 2022-06-102022-09-11 Journal: Genome Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Abbott anti-S antibody antibody antibody persistence Antibody Response Antibody titre antibody titres Antigen B.1 B.1.1.529 B.1.617.2 blood sample Blood samples Cohort collected control group control groups controls COVID-19 cross-protective Delta delta variant DiaSorin dose elicited followed by generate group healthcare healthcare worker Immune escape Immunity immunoassays increasingly individuals induce Infection investigated N antigen naïve naïve subject naïve subjects natural infection neutralisation neutralising Neutralising Antibodies nucleocapsid omicron Omicron variant performed persistence Post-infection presence of antibody question reactivity required Roche S antigen SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants sera Serosurvey serum significantly subject subjects tested the SARS-CoV-2 timepoints two groups vaccinated individuals vaccination Vaccine Vaccine development variant virus VoC VOCs weakened were used while [DOI] 10.1186/s13073-022-01066-2 PMC 바로가기 [Article Type] Article
Immunogenicity and safety of NVSI-06-07 as a heterologous booster after priming with BBIBP-CorV: a phase 2 trialBBIBP-CorV로 프라이밍한 후 이종 부스터로서의 NVSI-06-07의 면역원성과 안전성: 2상 시험Clinical Trial Published on 2022-06-062022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 1:1 Adverse reactions Alpha assigned BBIBP-CorV Beta boost booster booster vaccination conducted control groups coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine Delta double-blinded elicited followed by geometric mean geometric mean titer GMT GMTs group groups healthy Heterologous heterologous prime-boost homologous immunogenic immunogenicity immunogenicity assays inactivated increase Increases indicated individual Mild moderate Neutralizing neutralizing antibody omicron Omicron variant Participants Phase 2 phase 2 trial priming prototype randomised Randomly receive recipient Recombinant protein Safe safety profile SARS-CoV-2 SARS-CoV-2 variant significantly higher systemic adverse reaction three groups vaccination Vaccine variant VOCs [DOI] 10.1038/s41392-022-00984-2 PMC 바로가기 [Article Type] Clinical Trial
Accuracy and perceptions of teledentistry in KSA during the COVID-19 pandemic: A single-centre randomised controlled trialResearch article Published on 2022-06-012022-10-05 Journal: Journal of Taibah University Medical Sciences [Category] 임상, [키워드] Accuracy baseline Care clinical examination conditions control group control groups COVID-19 COVID-19 pandemic diagnose diagnoses Diagnosis group had more Health hospital hygiene in-person visit Intervention knowledge lockdown moderate no significant difference objective pandemic parallel-group participant Patient questionnaire randomised randomised clinical trial randomised controlled trial reported Result retrieved significantly single-blind study group subsequent Teledentistry telehealth the study group was used while [DOI] 10.1016/j.jtumed.2021.11.015 [Article Type] Research article
Tranilast as an Adjunctive Therapy in Hospitalized Patients with Severe COVID- 19: A Randomized Controlled Trial중증 COVID-19로 입원한 환자의 보조 요법으로서의 트라닐라스트: 무작위 대조 시험Randomized Controlled Trial Published on 2022-06-012022-09-11 Journal: Archives of medical research [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료제, [키워드] 1:1 addition adjuvant therapy Admitted Patient antiviral drug antiviral drugs antiviral therapy assigned Clinical findings clinical trial collected data Combination Comparisons control group control groups Controlled COVID COVID-19 Cytokine storm death effective Efficacy ENhance evaluate expression hospital Hospitalization hospitalized patient ICU IL-1 Inflammation Inflammatory cytokine inhibitor Intervention intervention group Iran Laboratory tests LDH Long NLR NLRP3 NLRP3 inflammasome O2 Saturation open Open-label Patient patients with COVID-19 Randomly Safe SARS-CoV-2 severe COVID-19 significantly lower therapeutic effect therapeutic effects therapy TNF Tranilast Tranilast. was used with COVID-19 [DOI] 10.1016/j.arcmed.2022.03.002 PMC 바로가기 [Article Type] Randomized Controlled Trial
Clinical efficacy and safety of interferon-β-containing regimens in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trialsCOVID-19 환자 치료에서 인터페론 베타 함유 요법의 임상 효능 및 안전성: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-05-012022-09-11 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] 95% CI Admission adverse event all-cause mortality rate Antiviral treatment benefit clinical Clinical efficacy ClinicalTrials control group control groups Controlled controlled trials COVID-19 Efficacy Efficacy and safety help hospitalized patient hospitalized patients ICU ICU admission IFN-β inception increased risk increased survival intensive care intensive care unit interferon Interferon-β Meta-analysis Mortality mortality rate no significant difference Patient patients with COVID-19 Placebo Randomized Randomized controlled trial RCT RCTs reduce regimen regimens risk Safe SARS-CoV-2 searched serious AE significant difference study group study groups systematic review Treatment with COVID-19 [DOI] 10.1080/14787210.2022.2004118 PMC 바로가기 [Article Type] Meta-Analysis
Efficacy of early transfusion of convalescent plasma with high-titer SARS-CoV-2 neutralizing antibodies in hospitalized patients with COVID-19코로나19 입원환자에서 고역가 SARS-CoV-2 중화항체로 회복기 혈장 조기 수혈 효과Observational Study Published on 2022-05-012022-09-12 Journal: Transfusion [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 30-Day mortality 30-day mortality rate 95% confidence interval Admission age analyzed anti-SARS-CoV-2 benefit Blood blood center operations cardiac disease case-control study CCP Control control groups Controlled trial convalescent plasma COVID-19 COVID-19 diagnosis COVID-19 patient Diagnosis early administration Efficacy Factor feature FFP transfusion high-titer CCP Hospital admission Hospitalization hospitalized patient hypoxemic interquartile investigated men Mortality Odds ratio Patient patients patients with COVID-19 plasma primary endpoint Prognostic factor reduction in renal required Respiratory failure SARS-CoV-2 neutralizing antibody selected shown therapeutic transfusion practices (adult). treated with COVID-19 [DOI] 10.1111/trf.16863 PMC 바로가기 [Article Type] Observational Study
Regdanvimab in patients with mild-to-moderate SARS-CoV-2 infection: A propensity score-matched retrospective cohort study경증에서 중등도의 SARS-CoV-2 감염 환자의 레그단비맙: 성향 점수 일치 후향적 코호트 연구Article Published on 2022-05-012022-09-12 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 진단, [키워드] age analyses Analysis applied Clinical efficacy Comorbidities Control control groups COVID-19 CT-P59 Day death disease disease severity Efficacy evaluated high risk Mild-to-moderate neutralizing antibody outcome Patient patients with COVID-19 patients with moderate Pneumonia potential benefit primary endpoint Propensity score proportion PSM reduced reducing reduction regdanvimab required retrospective cohort study risk Safety SARS-CoV-2 SARS-COV-2 infection severe disease significantly significantly lower supplemental oxygen Therapies therapy treated Treatment utility [DOI] 10.1016/j.intimp.2022.108570 PMC 바로가기 [Article Type] Article
Efficacy of pranayama in preventing COVID-19 in exposed healthcare professionals: A quasi-randomized clinical trialResearch article Published on 2022-05-012022-10-05 Journal: Journal of Ayurveda and Integrative Medicine [Category] 임상, [키워드] antibody antibody tests assigned asymptomatic infection baseline characteristics chain clinical trial comparable conducted control group control groups COVID-19 COVID-19 infection COVID-19 patient demographics detect Diagnosis Efficacy group hcp health care professionals healthcare higher risk hospitals immune function IMPROVE inclusion criteria India Infection Intervention intervention group nine outbreak participant Point Pranayama professional Rapid reaction recruited reduce Result RT-PCR Symptom Test tested yoga [DOI] 10.1016/j.jaim.2022.100586 [Article Type] Research article
Efficacy of melatonin in the treatment of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trialsCOVID-19 환자 치료에서 멜라토닌의 효능: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 임상, [키워드] Administered Admission bedtime Clinical efficacy Clinical outcome clinical outcomes clinical recovery ClinicalTrials Cochrane Library Control control group control groups coronavirus disease Coronavirus disease 2019 COVID-19 help IMPROVE intensive care intensive care unit admission investigated melatonin Meta-analysis Mortality Odds ratio outcome OVID Patient patients with COVID-19 Placebo primary outcome measure Randomized controlled trial Randomized controlled trials RCT RCTs receiving risk SARS-CoV-2 searched systematic review Three times daily Treatment Trial trials Web of Science [DOI] 10.1002/jmv.27595 PMC 바로가기 [Article Type] Meta-Analysis