Nanobiotechnology approaches for cardiovascular diseases: site-specific targeting of drugs and nanoparticles for atherothrombosisReview Published on 2022-02-082022-10-29 Journal: Journal of Nanobiotechnology [Category] COVID-19, [키워드] antibodies antigenic approach Atherosclerosis atherosclerotic cardiovascular disease complex diseases creating current CVD death diffusion Disease progression drug epitope expressed gene delivery lesion limitation limitations Nanobiotechnology Nanoparticles overcome pathological mechanism Perspective pharmacological progression Recombinant protein Side effect target Targeted drug delivery therapy thrombosis unique [DOI] 10.1186/s12951-022-01279-y PMC 바로가기 [Article Type] Review
Cases of acute coronary syndrome and presumed cardiac death prior to arrival at an urban tertiary care hospital in Pakistan during the COVID-19 pandemicResearch Article Published on 2022-02-032022-10-28 Journal: PLoS ONE [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] 95% CI analyzed Autopsy avoidance baseline characteristics cardiovascular disease Care conducted coronary syndrome country COVID-19 COVID-19 infection COVID-19 pandemic CVD dead death decrease died element expected Factor Frequency Health hospital Hospitalization in-hospital mortality include increases in pandemic Patient proportion reduction in reported Result severity verbal [DOI] 10.1371/journal.pone.0263607 PMC 바로가기 [Article Type] Research Article
An analytical model of population level chronic conditions and COVID-19 related hospitalization in the United StatesResearch Published on 2022-02-012022-10-28 Journal: BMC Public Health [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Admission age aligned baseline black cardiovascular disease chronic condition chronic conditions COVID-19 COVID-19 patient cumulative CVD decrease diabete diabetes Evidence Factor health system higher risk Hospitalization hypertension ICU ICU admission ICU admission rate intensive care management outcome pandemic population level Prevalence Probability provide public health reduction Result retrospective System the United State World Health Organization [DOI] 10.1186/s12889-022-12531-3 PMC 바로가기 [Article Type] Research
Cardio-Oncology in the COVID Era (Co & Co): The Never Ending StoryCardiovascular Medicine Published on 2022-01-282022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] abnormal immune response Abnormalities active cancer Affect attack byproduct Cancer cancer patient Cardiotoxicity cardiovascular disease Care Coagulation COVID COVID-19 COVID-19 pandemic COVID-19 vaccines CVD Cytokines damaged described diabetes Efficacy ending Endothelial dysfunction endothelial function Endothelium feature hypertension include Infection Inflammation Intensive likelihood mechanism myocarditis Non-communicable disease outcome pandemic pandemic era Pathogenesis pathophysiologic pathophysiology Patient persistence pharmacological phenotype platform problem rapid expansion recommendation reduced SARS-CoV-2 SARS-CoV-2 infections Side-effect Survivors Symptoms syndemic telehealth the vaccine Toxicity Trigger vaccination variant vascular beds vascular disease venous ventricular ventricular dysfunction [DOI] 10.3389/fcvm.2022.821193 PMC 바로가기 [Article Type] Cardiovascular Medicine
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38 + macrophages and NAD + declineArticle Published on 2022-01-272022-10-04 Journal: Cell Death & Disease [Category] 바이오마커, [키워드] addition age Bone marrow BPIFB4 cardiovascular disease CD38 CD45 Cell change characterized chronic inflammation clinical implication consequence contributing to CVD Deleterious described disorders driving event exceptional frailty Frequency functional Gal Haplotype healthy IL10 IL1β IL6 immune Immune cell immune system Immunological disorders in vivo increase in Inflammation Inflammatory diseases Macrophage mice morbidity and mortality offer pathophysiological Peripheral blood phenotype plasma Prevent previous study pro-inflammatory monocyte progression reduce reduced reduction reduction in senescence senescent shown spleen sustained systemic inflammation therapeutic therapeutic target tissue-resident macrophage transfer treated variant vasculature [DOI] 10.1038/s41419-022-04535-z PMC 바로가기 [Article Type] Article
The COVID-19 Pandemic Lowers Active Behavior of Patients with Cardiovascular Diseases, Healthy Peoples and AthletesReview Published on 2022-01-192022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] alternative athlete Behavior cardiovascular cardiovascular disease conducted coronavirus COVID-19 COVID-19 pandemic CVD decrease detraining Google Scholar Health healthy individuals healthy subject healthy subjects in healthy individuals lockdown Lower maintain pandemic Pandemics Patient patients physical activity quarantine reduction reported Sedentary behavior significant decrease significant increase [DOI] 10.3390/ijerph19031108 PMC 바로가기 [Article Type] Review
Clinical Characteristics, Outcomes, and Risk Factors of Disease Severity in Patients With COVID-19 and With a History of Cerebrovascular Disease in Wuhan, China: A Retrospective StudyNeurology Published on 2022-01-112022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] 95% CI acute respiratory syndrome Admission adverse outcome adverse outcomes age albumin analyses Analysis analyzed Blood urea nitrogen C-reactive protein cerebrovascular Cerebrovascular disease chronic obstructive clinical Clinical characteristics clinical feature Clinical outcome clinical study Comorbidities confirmed case confounding effect consecutive patient Coronary heart disease coronavirus Coronavirus disease 2019 COVID-19 CVD death Decreased diabetes difference event Factor higher risk history Hospitalization Huoshenshan Hospital hypertension incidence intensive care investigated lactate dehydrogenase lymphocyte Lymphocyte count mechanical ventilation multivariate logistic regression neutrophil Odds ratio Older pandemic Patient patients with COVID-19 propensity score matching pulmonary disease retrospective risk factor Risk factors Sex Shock single-center smoking two group White blood cell Wuhan [DOI] 10.3389/fneur.2021.706478 PMC 바로가기 [Article Type] Neurology
Not Only High Number and Specific Comorbidities but Also Age Are Closely Related to Progression and Poor Prognosis in Patients With COVID-19Medicine Published on 2022-01-072022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age cardiovascular disease Characteristics CHB Chinese Chronic Hepatitis B Chronic kidney disease chronic obstructive CKD clinical clinician Comorbidities Comorbidity COPD Coronavirus disease 2019 (COVID-19) correlated correlation Correlation analysis COVID-19 COVID-19 patient COVID-19 patients CVD Diabetes Mellitus died disease Disease progression disease severity eight Factor Fatty liver FIVE Gout group groups hypertension NAFLD Negative conversion number number of comorbidities number of comorbidity Older outcome outcomes patients with comorbidity patients with COVID-19 Poor poor prognosis predict Predictive Prognosis progression pulmonary disease severe COVID-19 patients Specific virus were assessed [DOI] 10.3389/fmed.2021.736109 PMC 바로가기 [Article Type] Medicine
Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases Reviews Published on 2022-01-062022-10-05 Journal: Hypertension research : official journal of the Ja [Category] 바이오마커, [키워드] Administered adrenomedullin bloodstream cardiovascular disease clinical trial CVD derivative derivatives Diseases endothelial expand expected heart failure increase in Infarction Inflammation Inflammatory bowel disease intervals less limitation marker Myocardial infarction peptide physiological functions pulmonary hypertension reduce restrict severe inflammation subcutaneous injection therapeutic translational Vascular [DOI] 10.1038/s41440-021-00806-y [Article Type] Reviews
COVID-19 prevention with subcutaneous administration of the monoclonal antibodies casirivimab and imdevimab: Subgroup analysis in participants with cardiovascular disease and diabetesConference abstract Published on 2021-12-012022-10-05 Journal: American heart journal [Category] 임상, [키워드] 1:1 Administered administration adverse event Analysis Asymptomatic Asymptomatic COVID-19 baseline Baseline serology cardiovascular disease COVID-19 CVD diabete diabetes diagnosed Efficacy Evidence figure headache hypertension Immunity increased risk index case individual monoclonal antibody monoclonal antibody combination participant performed phase Placebo positive post-hoc analysis prevented primary endpoint proportion Randomized reduced REGEN-COV reported Result risk risk reduction RT-qPCR SARS-CoV-2 seronegative severe disease study participant subcutaneously symptomatic infection symptomatic SARS-CoV-2 infection table Treatment Trial [DOI] 10.1016/j.ahj.2021.10.067 [Article Type] Conference abstract