COVID-19-related arrhythmias and the possible effects of ranolazineResearch article Published on 2021-04-012022-10-05 Journal: Medical Hypotheses [Category] 치료제, [키워드] Administered angina pectoris Antiviral approved arrhythmia Arrhythmias blood pressure Cardiac arrhythmia cardiac effect Community Complication COVID-19 COVID-19 pandemic COVID-19 patient cytokine cytokine expression disease drug Effect effective global healthcare Infection management manifestation modulating Potassium previous study producing Ranolazine reduced reported SARS-CoV-2 severity shown Side effects sodium therapeutic agent Treatment with COVID-19 [DOI] 10.1016/j.mehy.2021.110545 [Article Type] Research article
Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients중환자 코로나19 환자의 혈장 사이토카인 수치 증가 및 장기 부전 및 30일 사망률과의 상관관계Article Published on 2021-02-012022-09-11 Journal: Cytokine [Category] SARS, 바이오마커, [키워드] 30-Day mortality abdominal surgery Acute kidney injury Admission Biomarkers Care caused Cohort controls Corona virus correlated correlation COVID-19 Critically ill critically ill COVID-19 patients cytokine cytokine expression cytokine response Cytokine storm Cytokine storm syndrome Cytokines death demonstrated expression IL-17A IL-1ra IL-4 IL-6 IL-8 increase increase in Increased induce Infection Inflammation inflammatory markers inflammatory mediator Inflammatory mediators Inflammatory response Informed consent initial symptoms intensive care IP-10 kidney Kidney injury MCP-1 median mediators moderate Mortality organ damage Organ failure Patient patients PCR-confirmed PCR-confirmed COVID-19 plasma Plasma cytokine plasma sample quantified Respiratory failure SARS CoV SARS CoV-2 SOFA score the strongest was obtained [DOI] 10.1016/j.cyto.2020.155389 PMC 바로가기 [Article Type] Article
Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2상호 정보 알고리즘을 통한 사이토카인 순위는 SARS-CoV-2에 감염된 환자의 질병 중증도를 나타내는 사이토카인 프로필의 상관 관계를 나타냅니다.Short Report Published on 2021-01-142022-09-12 Journal: eLife [Category] 진단, [키워드] acute respiratory syndrome age Algorithm Biomarker cause change changes in Chest clinical variable clinical variables clinician coronavirus COVID-19 COVID-19 disease severity CSS cytokine cytokine expression cytokine profile Cytokine storm develop disease severity Donor evaluate Hospitalization Human immune response infected with SARS-CoV-2 information Intervention Macrophage macrophage activation syndrome mechanism methodology mutual information algorithm Oxygen requirement Pathogenesis Patient Plasma cytokine plethora predict Predictive presenting Protein provided question raising receptor SARS-CoV-2 SARS-COV-2 infection score severely ill patients subset symptomatic individuals the disease variable [DOI] 10.7554/eLife.64958 PMC 바로가기 [Article Type] Short Report
How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infectionsReview Published on 2020-10-122022-11-01 Journal: Gut Pathogens [Category] COVID-19, [키워드] “cytokine storm” Abnormalities activation of platelets addition administration anorexia Anxiety boost can be used cause Coagulation Coronavirus infection COVID-19 COVID-19 pandemic Critically ill patient cytokine expression defend diarrhea diarrhoea digestive Factors feature fraction gut microbiota Health healthy helping Human immune immune system immunomodulatory in healthy individual individual intestinal inflammation microbial infection microbial infections modulated novel coronavirus SARS-CoV-2 plasma previous study reduce reduced respiratory tract infection Respiratory virus infection Respiratory virus infections respond risk Saccharomyces cerevisiae shown Stress Support Symptoms synergistic Vaccine viral infections vitamins C vomiting weakened with COVID-19 yeast [DOI] 10.1186/s13099-020-00385-2 PMC 바로가기 [Article Type] Review
Preliminary Post-Mortem COVID-19 Evidence of Endothelial Injury and Factor VIII HyperexpressionArticle Published on 2020-08-092022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] ACE2 acute respiratory distress all subject antibody ARDS Autopsy Biomarker cellular Complete concerning COVID-19 COVID-19 diagnostic COVID-19 infection cytokine expression death diagnosing Diagnosis died Diffuse alveolar damage effort endothelial damage evidence of expressed factor VIII forensic pathology forensic science form FVIII histological Hypothesis immunohistochemistry Infection interstitial pneumonia lung Newborn outbreak pandemic pathology performed Pneumonia Post-mortem post-mortem examination public health Research severity specimens Surveillance Survivors susceptibility syndrome two subject Vascular vascular disease viral pathogenesis widespread [DOI] 10.3390/diagnostics10080575 PMC 바로가기 [Article Type] Article
Successive Passage In Vitro Led to Lower Virulence and Higher Titer of A Variant Porcine Epidemic Diarrhea VirusArticle Published on 2020-04-012022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Amino acid caused characterized China cytokine expression Cytokines deletions diarrhea epidemic diarrhea experiments expression fecal flow cytometry Genetic growth Host IFN-β IL1β IL6 in vitro in vivo indicated inhibit Lower nucleotide occurred ORF1a/b ORF3 passage passages pathogenicity PEDV Point mutation Porcine epidemic diarrhea virus Real-time PCR Replication resulting sequenced significantly Spread stability TCID titer TNF-α variant Vero Cell viral titer virulent virus virus isolate vomiting [DOI] 10.3390/v12040391 PMC 바로가기 [Article Type] Article
Immune response of mice to non-adapted avian influenza A virusArticle Published on 2015-12-012023-06-03 Journal: Acta virologica [Category] 조류인플루엔자, [키워드] avian influenza A virus cytokine expression viral protein synthesis.. virus replication in mice virus-neutralizing antibodies [DOI] 10.4149/av_2015_04_350
Differentiated phenotypes of primary murine alveolar epithelial cells and their susceptibility to infection by respiratory virusesArticle Published on 2013-04-292022-11-01 Journal: Virus research [Category] Coronavirus, 신종인플루엔자, [키워드] activating alveolar cell alveolar epithelial cell alveolar epithelial cells ATII Cell cell type cells contribute coronavirus correlated Critical Culture cytokine cytokine expression cytokine response Cytokines determine determined different disease severity epithelial cell exhibited Express expression Factor H1N1 Host IAV identify IL-1β immune responses in vitro model in vivo increased expression Infected Infection influenza A influenza A virus lung Lungs maintain Mouse-adapted SARS-coronavirus mouse-adapted SARS-CoV mRNA murine murine coronavirus murine model Pathogenesis pathology phenotype quantified respiratory viral infection respiratory virus respiratory viruses response robust SARS-CoV severe spread to susceptibility susceptible target type I Type I pneumocyte Type II pneumocyte v2163 viral infection viral infections viral pathogenesis virus viruses while [DOI] 10.1016/j.virusres.2013.04.008 PMC 바로가기 [Article Type] Article