Dilution – Page 3 – Communicable Diseases Research

Hydroxamate and thiosemicarbazone: Two highly promising scaffolds for the development of SARS-CoV-2 antivirals

하이드록사메이트 및 티오세미카바존: SARS-CoV-2 항바이러스제 개발을 위한 2개의 매우 유망한 스캐폴드

Article

Published on 2022-07-012022-09-11
Journal: Bioorganic chemistry [Category] COVID19(2023년), SARS, 치료제,

Evaluation of Four Point of Care (POC) Antigen Assays for the Detection of the SARS-CoV-2 Variant Omicron

SARS-CoV-2 변이체 오미크론 검출을 위한 4가지 진료 시점(POC) 항원 분석 평가

Article

Published on 2022-06-292022-09-11
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] Abbott Analysis analytical sensitivity Antigen assays Asymptomatic average Cell culture contributing to correlated Cycle threshold value ddPCR Delta delta variant detect detectable detection diagnostics digital PCR Dilution discrepancies discrepancy Ensuring evaluated Genome highest Infectious virus infectious virus titer limit limit of detection LOD log manuscript molecular N gene omicron Omicron variant POC Point point of care point-of-care positive quantified Rapid antigen tests Real-time PCR reduced replicate RNA SARS-CoV-2 specimen Spread swab sample symptomatic tested the SARS-CoV-2 vaccinated individuals variant variant of SARS-CoV-2 Viral viral stock viral stocks virus stock virus titer
[DOI] 10.1128/spectrum.01025-22 PMC 바로가기 [Article Type] Article

Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulation

SARS-CoV-2 감염 및 스파이크 형질감염 세포에 결합하고 NK 세포 탈과립을 매개하는 항체의 능력을 평가하기 위한 유세포 분석 기반 분석법 개발

Article

Published on 2022-06-012022-09-11
Journal: Cytometry. Part A : the journal of the Internation [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제,

[키워드] antibody Antibody binding Antibody Response Antibody responses Antibody titer Antibody titers assays binding capture Cell cells Clinical studies correlation COVID-19 degranulation demonstrated detect determine develop development Dilution dilution sery Efficiency effort elicited facilitate function functional antibody response healthy control high correlation Immunity IMPROVE infected cell infected cell. infected cells infected individuals magnitude moderate NK cell NK cell degranulation outcome overlap pandemic plasma platform ranged reduce response response rates responses SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2-infected cell SARS-CoV-2-infected cells SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Spearman the SARS-CoV-2 transfected cells Undetermined vaccination
[DOI] 10.1002/cyto.a.24552 PMC 바로가기 [Article Type] Article

Early administration of COVID-19 convalescent plasma with high titer antibody content by live viral neutralization assay is associated with modest clinical efficacy

살아있는 바이러스 중화 분석에 의한 고역가 항체 함량을 가진 COVID-19 회복기 혈장의 조기 투여는 보통의 임상 효능과 관련이 있습니다

Article

Published on 2022-06-012022-09-11
Journal: American journal of hematology [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] absolute reduction administration administration of CCP antibody Antibody titer benefit CCP clinical benefit Clinical efficacy convalescent plasma correlation COVID-19 COVID-19 convalescent plasma Cox regression death rate death rates determined by develop Dilution Efficacy evaluate evaluated Hospitalization hospitalized patient hospitalized patients inhibitory intubated patients multivariable Cox regression neutralized Neutralizing antibody titer Non-intubated non-intubated patient non-intubated patients Patient receiving Risk factors shown stratified titer transfused Treatment two groups Viral viral neutralization viral variant Viral variants was performed with COVID-19
[DOI] 10.1002/ajh.26531 PMC 바로가기 [Article Type] Article

Tool for tracking all-cause mortality and estimating excess mortality to support the COVID-19 pandemic response

Article

Published on 2022-05-252022-11-15
Journal: Western Pacific Surveillance and Response Journal [Category] COVID19(2023년), SARS, 치료기술,

Outbreak investigation of airborne transmission of Omicron (B.1.1.529) – SARS-CoV-2 variant of concern in a restaurant: Implication for enhancement of indoor air dilution

오미크론(B.1.1.529) 공중전파 발생 조사 - 식당에서 우려되는 SARS-CoV-2 변종: 실내 공기 희석도 향상에 대한 시사점

Article

Published on 2022-05-152022-09-11
Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 변종,

SARS-CoV-2 detection in multi-sample pools in a real pandemic scenario: A screening strategy of choice for active surveillance

실제 전염병 시나리오에서 다중 샘플 풀에서 SARS-CoV-2 탐지: 능동 감시를 위한 선별 전략 선택

Article

Published on 2022-04-012022-09-11
Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술,

Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose

두 번째 백신 접종 후 180일 동안 의료 종사자(HW)에서 BNT162b 백신 2회 접종 후 세포 및 체액 면역 반응 및 돌발 감염

Article

Published on 2022-03-312022-09-12
Journal: Frontiers in Public Health [Category] MERS, SARS, 진단,

[키워드] age all subject binding antibody BNT162b Breakthrough infection Cytopathic effect Day Delta VOC Dilution domain enrolled evaluated groups healthcare Healthcare workers highest Hospitalization human serum humoral Humoral response identify IFN-γ IgG IgG level IgG levels IgG titer Immunity individuals Infection information Live virus long-lasting maintain microneutralization mRNA vaccine mRNA vaccines neutralized neutralizing antibody Neutralizing antibody titer neutralizing responses Neutralizing titer Older Predictive protective immunity Protein remained response SARS-CoV-2 second secretion shown stages subject subjects T-cell Response tested threshold Vaccine virus Volume was determined worker Wuhan strain
[DOI] 10.3389/fpubh.2022.847384 PMC 바로가기 [Article Type] Article

BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant Recipients

BNT162b2 3차 부스터 용량은 신장 이식 수혜자의 RBD IgG 및 중화 항체 모두에 의해 평가된 체액 반응을 상당히 증가시킵니다

Article

Published on 2022-03-212022-09-11
Journal: Transplant International [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% CI Allograft antibody Antibody Response BNT162b2 BNT162b2 vaccine booster COVID-19 COVID-19 vaccine develop Diabetic diabetic nephropathy Dilution domain dose effective ESRD geometric mean geometric mean titer geometric mean titers GMT GMTs group had no humoral Humoral response IgG Immunosuppression increase independent predictor independent predictors mycophenolic acid negative and positive nephropathy Neutralizing antibodies neutralizing antibody non-responder non-responders of BNT162b2 Patient positive predictor pseudo-virus RBD RBD IgG Receptor-binding domain recipient recipients remained renal Renal transplantation Responder responders response response rate SARS-CoV-2 secondary to seroconverted significant increase stratified systemic systemic AEs the vaccine Transplant Vaccine were recorded
[DOI] 10.3389/ti.2022.10239 PMC 바로가기 [Article Type] Article

Characterization of a SARS-CoV-2 spike protein reference material

SARS-COV-2 스파이크 단백질 기준 물질의 특성

Paper in Forefront

Published on 2022-03-092022-09-10
Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료기술,

[키워드] absorbance Amino acid Analysis assist calculated Canada changes in characterization Combination Community Concentration Council COVID-19 COVID-19 pandemic density development diagnostic diagnostic testing Dilution fraction glycoprotein glycosylated homogeneity hydrolysis Isotope dilution lack leads Liquid chromatography mass spectrometry material molar concentration molecular weight National Research Council Canada Protein reference reference material Reference materials reported Research SARS-CoV-2 SARS-CoV-2 spike protein scattering Spike protein stability Standardization supplementary material Tandem mass spectrometry test results the spike protein trimeric Tryptophan tyrosine value were assessed
[DOI] 10.1007/s00216-022-04000-y PMC 바로가기 [Article Type] Paper in Forefront