Portable Electrochemical Biosensors Based on Microcontrollers for Detection of Viruses: A Review바이러스 검출을 위한 마이크로컨트롤러 기반 휴대용 전기화학 바이오센서: 리뷰Review Published on 2022-08-222022-09-11 Journal: Biosensors [Category] 치료기술, [키워드] alternative amperometry amplification analyte biosensor can be used costly COVID-19 pandemic current Cycling detection detection technique Diagnostic method diagnostic methods diagnostics DNA amplification Early detection electrochemical biosensors Electrochemical impedance spectroscopy element elements explained integration Isolation lab Laboratory Microcontroller Microfluidics mitigate Modification offer Outbreaks pandemic patients point-of-care potentiostat producing Rapid test respiratory viruses review RT-LAMP RT-PCR transducer turnaround time virus virus detection voltammetry zoonotic disease [DOI] 10.3390/bios12080666 PMC 바로가기 [Article Type] Review
Agent Simulation Model of COVID-19 Epidemic Agent-Based on GIS: A Case Study of Huangpu District, ShanghaiGIS 기반 COVID-19 전염병 에이전트의 에이전트 시뮬레이션 모델: 상하이 황푸 지역의 사례 연구Article Published on 2022-08-182022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] activities addition adjust agent Agent-based simulation model applied caused Characteristics China complex complexity country COVID-19 COVID-19 epidemic COVID-19 outbreak COVID-19 transmission COVID-19 virus disease District effective element epidemiological form function Health hypothetical information Intervention lockdown lockdown intervention Model Mutation nucleic acid Nucleic acid detection official outbreak pandemic parameters Population Population mobility Prevention and control public health public health authorities public health authority Public health intervention reported risk Risk assessment Shanghai Simulation Society spread of COVID-19 Travel Treatment WHO [DOI] 10.3390/ijerph191610242 PMC 바로가기 [Article Type] Article
Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall Research Published on 2022-08-112022-10-05 Journal: Scientific Reports [Category] 유전자 메커니즘, [키워드] accelerated Affect analyzed animal model applied Artery association Atherosclerosis atherosclerotic lesion Blood blood cell carotid change circulating circulating cell contribute dependent on disease distribution element elevated Flow Hypothesis imaging increased expression Inflammation Interaction Local marker mechanism mouse model pathology Patient plaque poor prognosis Protein red blood cell Red cell researcher resonance subject Variation variety Vascular vessel wall [DOI] 10.1038/s41598-022-17847-z [Article Type] Research
A disturbed balance between blood complement protective factors (FH, ApoE) and common pathway effectors (C5a, TCC) in acute COVID-19 and during convalesce Research Published on 2022-08-112022-10-05 Journal: Scientific Reports [Category] SARS, 바이오마커, 치료법, [키워드] activate Activation acute COVID-19 affected Blood C-reactive protein C5a Cluster collected complement Complement activation complex conditions convalescent plasma treatment correlated COVID-19 COVID-19 patients CRP death Deep venous thrombosis demonstrated DVT effector electronic medical records element elevated event HMGB1 homeostasis IgA IgG IgM IL-6 immune response immune system immunological Immunological response incidence Increased Infection Inflammatory response investigated knowledge marker Mortality Necrosis non-specific pathway Patient patients hospitalized PCR-confirmed diagnosis protective factor RAGE remained SARS-COV-2 infection SARS-CoV-2 spike protein shown tissue Treatment viral burden Viral load was collected were assessed [DOI] 10.1038/s41598-022-17011-7 [Article Type] Research
Metallomic and Untargeted Metabolomic Signatures of Human Milk from SARS-CoV-2 Positive MothersObservational Study Published on 2022-08-012022-10-05 Journal: Molecular nutrition & food research [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome alcohols Aluminium amino acids Aminoacyl-tRNA Concentration conducted Conjugates control group coronavirus COVID-19 derivatives difference element elements Fatty acid Health Human human milk implication increase Infection information metabolite metabolomic metabolomics milk mother pathway peptides plasma positive profile provide purine quantification recorded reduce Research SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection signature significantly symptomatic and asymptomatic tyrosine unique with COVID-19 [DOI] 10.1002/mnfr.202200071 PMC 바로가기 [Article Type] Observational Study
A Systematic Study on the Optimal Nucleotide Analogue Concentration and Rate Limiting Nucleotide of the SARS-CoV-2 RNA-Dependent RNA PolymeraseSARS-CoV-2 RNA 의존성 RNA 중합효소의 최적 뉴클레오티드 유사체 농도 및 속도 제한 뉴클레오티드에 대한 체계적인 연구Article Published on 2022-07-272022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 치료제, [키워드] adenosine analogue Antiviral compounds antiviral efficacy approved assays clinically competition complex Concentration condition cordycepin coronavirus COVID-19 COVID-19 pandemic COVID-19 treatment drug effective Efficiency EIDD-2801 element GS-443902 GS-5734 GTP in vitro new SARS-CoV-2 NUC-7738 nucleoside nucleotide nucleotides physiological Rate RdRP Remdesivir Repurposed drug RNA RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 RdRp SARS-CoV-2 replication sensitivity the SARS-CoV-2 Treatment [DOI] 10.3390/ijms23158302 PMC 바로가기 [Article Type] Article
Mortality Predictors in Severe SARS-CoV-2 InfectionObservational Study Published on 2022-07-182022-10-05 Journal: Medicina [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age Algorithm changes in Cluster Clusters Community COVID-19 CT scan density clusters element evaluate evaluated Evolution form hemoglobin high mortality hospital hypoxic respiratory failure IMPROVE include increase interstitial lactate dehydrogenase lesions less lung lung involvement lung lesion Lymphocytes material Mortality Myoglobin non-survivor Non-survivors objective Observational cohort study oxygen flow PaO parameter parameters Patient performed Platelets Prediction score Predictive predictor Prognosis pulmonary involvement pulmonary lesion Quantitative quantitative evaluation radiological raising Regression model Result retrospective risk factor SARS-CoV-2 SARS-CoV-2 pneumonia semi-quantitative Sensitivity and specificity serum albumin serum creatinine Severe case severe COVID-19 Survivors [DOI] 10.3390/medicina58070945 PMC 바로가기 [Article Type] Observational Study
A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys Research Published on 2022-07-132022-10-05 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] Analysis animal model Cell cell type cellular cellular processes chromatin developmental element feature gene expression pattern gene regulatory network heterogeneity humans identify Laboratory molecular multiple organ multiple tissue Non-human non-human primate organ-specific organs provide RNA sequencing data similarity single-cell single-cell level trajectory transcriptomic transcriptomic data valuable resource [DOI] 10.1038/s41467-022-31770-x [Article Type] Research
Variations of SARS-CoV-2 in the Iranian population and candidate putative drug-like compounds to inhibit the mutated proteinsResearch article Published on 2022-07-112022-10-05 Journal: Heliyon [Category] 신약개발, [키워드] addition Affect antibody appear Ardabil benefit Candidate putative drug-like compounds Ciclesonide complex Compound conserved COVID-19 diagnosing DNA docked element Evolution Frame Genetic Genetic variant help indels indicated inducer Infection inhibit inhibitor Interaction Iran mechanism of action Meta-analysis mutated Mutation Nonstructural proteins (NSPs) Novel coronavirus NSP8 nucleotide nucleotide mutation Open reading frame (ORF) ORF1ab Orf9b Oxford polyproteins Potential Protein reported responsible resveratrol SARS-CoV-2 SARS-CoV-2 gene sequence sequenced Spread Substitution the SARS-CoV-2 Topic treating COVID-19 Vaccine design Viral proteins viral replication virus Wuhan, China [DOI] 10.1016/j.heliyon.2022.e09910 [Article Type] Research article
Dengue Infection – Recent Advances in Disease Pathogenesis in the Era of COVID-19뎅기열 감염 - COVID-19 시대의 질병 병인의 최근 발전Review Published on 2022-07-062022-09-12 Journal: Frontiers in Immunology [Category] MERS, 진단, [키워드] activated activating advance anti-SARS-CoV-2 Antibody-dependent enhancement antibody-dependent enhancement (ADE) consequence COVID-19 cross-protection cross-reactivity cytokine Cytokine storm demonstrated Dengue dengue (DENV) dengue virus element Endemic endothelial Endothelial dysfunction Host host-virus interactions immune Immune cell immune response Immunopathogenesis impairment implication Inflammasome inflammatory cascade Pathogenesis plasmablast plasmablasts preclinical study recent response secondary infections serotype severe disease Severity of disease Surveillance virus [DOI] 10.3389/fimmu.2022.889196 PMC 바로가기 [Article Type] Review