Adipose tissue is a predictor of 30-days mortality in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniaeResearch Article Published on 2022-02-212022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] 30-Day mortality 95% CI 95% confidence interval adipose Adipose tissue age all-cause mortality analyzed association Bacterial bloodstream bloodstream infection body composition BSI Carbapenem-resistant Klebsiella pneumoniae caused clearance complications COVID-19 Cox regression model effective eligible patient Factor hazard ratio high mortality hospital Infection investigated Klebsiella pneumoniae Mortality nomogram Patient patients performed physician Pneumonia poor prognosis previous study prognosis of patient Prognostic value Result SAT severity Skeletal muscle SOFA score statistical significance suffered suggested TAT tissue visceral [DOI] 10.1186/s12879-022-07108-9 PMC 바로가기 [Article Type] Research Article
Impact of Insurance Benefits and Education on Point-of-Care Ultrasound Use in a Single Emergency Department: An Interrupted Time Series AnalysisArticle Published on 2022-02-012022-10-30 Journal: Medicina [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Analysis benefit changed chose clinician coronavirus disease Coverage defined education eligible patient Emergency emergency department evaluate help Impact increase in insurance Intensive Interrupted Intervention material objective pandemic Patient physician Point-of-Care ultrasound Result Retrospective study Sery significantly South Korea time treat Ultrasonography Ultrasound [DOI] 10.3390/medicina58020217 PMC 바로가기 [Article Type] Article
Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trialResearch article Published on 2022-02-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 신약개발, 임상, 치료법, [키워드] adaptive Adverse drug reactions age ambulatory patient Antigen assigned Bayesian framework Brazil Care clinical benefit clinical outcomes clinical trial Committee conducted confidence COVID-19 COVID-19 emergency defined determine disease severity early treatment Effect effective eligible patient Enrollment female finding foundation funding high-risk patient hospital Hospitalization initiated interval Intervention metformin monitoring Mortality no difference no significant difference not different observational study outcome outpatients participant Participants Patient Placebo placebo group platform positive Primary outcome Probability proportion randomization Randomized randomized clinical trial randomized patient randomized trial Randomly receive recruited reducing risk risk factor Safety SARS-CoV-2 secondary Secondary outcomes supported symptomatic adult therapeutic TOGETHER Trial transfer treating COVID-19 Treatment Trial viral clearance with COVID-19 worsening [DOI] 10.1016/j.lana.2021.100142 [Article Type] Research article
Experience of Rwanda on COVID-19 Case Management: From Uncertainties to the Era of Neutralizing Monoclonal AntibodiesCOVID-19 사례 관리에 대한 르완다의 경험: 불확실성에서 단일 클론 항체 중화 시대까지Article Published on 2022-01-182022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, [키워드] Anti-inflammatory drugs Antibiotic therapy anticoagulation Antiviral effect approach Asymptomatic bamlanivimab broad-spectrum antibiotic Care Case fatality rate Clinical management COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 therapeutics COVID-19 vaccine eligible patient Eligible patients experience Fatality rate Favipiravir guidelines Healthcare system hyperglycemia index case Intervention interventions management management guidelines measure Mild monoclonal antibodies neutralizing monoclonal antibodies neutralizing monoclonal antibody outcomes Patient provided receiving remained Rwanda therapeutic Therapeutic approach Therapeutics treated treatment for COVID-19 Uncertainty Viral viral clearance [DOI] 10.3390/ijerph19031023 PMC 바로가기 [Article Type] Article
Remdesivir and dexamethasone as tools to relieve hospital care systems stressed by COVID-19: A modelling study on bed resources and budget impactResearch Article Published on 2022-01-122022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] affected amplified amplitude Care COVID-19 outbreak COVID-19 patients decrease Dexamethasone drug Effect eligible eligible patient epidemiological data examined France generate High-flow oxygen hospital Hospital stay ICUs Impact intensive care limit low-flow oxygen medications Neutral observé Patient Randomized control trials reductions in Remdesivir required resource second wave significantly Strategy treating Treatment [DOI] 10.1371/journal.pone.0262462 PMC 바로가기 [Article Type] Research Article
Comparing machine learning algorithms for predicting COVID-19 mortalityResearch Published on 2022-01-042022-10-27 Journal: BMC Medical Informatics and Decision Making [Category] COVID-19, [키워드] Accuracy Admission age alanine aminotransferase Algorithm artificial intelligence Ayatollah calculated can be used characteristic Clinicians Confusion coronavirus coronavirus disease COVID-19 COVID-19 mortality deaths demonstrated Dyspnea eligible patient Experimental result facilitate high risk hospitalized patient hospitalized patients ICU admission information interquartile Intervention Iran lowest machine machine learning machine learning algorithm men Metrics Mortality Oxygen therapy Platelet Precision predict Prediction hospital mortality Predictive predictive models predictor predictors random Result risk of death ROC sensitivity specificity study participant survivor the median the patient women [DOI] 10.1186/s12911-021-01742-0 PMC 바로가기 [Article Type] Research
Comparing machine learning algorithms for predicting COVID-19 mortalityResearch Published on 2022-01-042022-10-27 Journal: BMC Medical Informatics and Decision Making [Category] Coronavirus, COVID-19, SARS, [키워드] Accuracy Admission age alanine aminotransferase Algorithm artificial intelligence Ayatollah calculated can be used characteristic Clinicians Confusion coronavirus coronavirus disease COVID-19 COVID-19 mortality deaths demonstrated Dyspnea eligible patient Experimental result facilitate high risk hospitalized patient hospitalized patients ICU admission information interquartile Intervention Iran lowest machine machine learning machine learning algorithm men Metrics Mortality Oxygen therapy Platelet Precision predict Prediction hospital mortality Predictive predictive models predictor predictors random Result risk of death ROC sensitivity specificity study participant survivor the median the patient women [DOI] 10.1186/s12911-021-01742-0 PMC 바로가기 [Article Type] Research
Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trialRandomized Controlled Trial Published on 2022-01-012022-10-05 Journal: The Lancet. Global health [Category] Fulltext, SARS, 신약개발, 임상, 치료법, [키워드] 1:1 95% CI Abstract Adaptive platform trial adverse event age Analysis Arm assigned average Bayesian Bayesian credible interval BCI Brazil Care clinical trial composite endpoint COVID-19 COVID-19 emergency death defined diagnosed early treatment Effect Efficacy eligible patient events Evidence female finding foundation groups hospital hospitalisation hospitalisations indicate initiated intention to treat intention-to-treat analysis Intervention material modified intention-to-treat no significant difference Odds ratio Outpatient participant Patient per-protocol analysis per-protocol population Placebo placebo-controlled platform positive potential participant Primary outcome Probability progression proportion protocol randomisation randomised Randomly receiving recent reduced Registered reported risk risk factor SARS-CoV-2 screened severe disease symptomatic symptomatic patient the placebo group therapeutic threshold transfer transferred translation Treatment treatment allocation treatment group Trial with COVID-19 [DOI] 10.1016/S2214-109X(21)00448-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Characteristics of COVID-19 in patients with multiple sclerosisResearch article Published on 2022-01-012022-10-05 Journal: Multiple sclerosis and related disorders [Category] SARS, 치료제, [키워드] addition Admission age Altered mental status association carried CD20 change changed COVID-19 COVID-19 in patient COVID-19 infection COVID-19 severity COVID-19 symptoms death rate Dyspnea eligible patient expired female form Hospital admission hospitalized patient increased risk Iran MRI multicenter multiple sclerosis nine pandemic Patient patients patients with COVID-19 Prevalence relapsing Result resulting severe COVID-19 symptoms steroid was performed [DOI] 10.1016/j.msard.2021.103437 [Article Type] Research article
ENhAncing Lifestyle Behaviors in EndometriaL CancEr (ENABLE): A Pilot Randomized Controlled TrialRandomized Controlled Trial Published on 2022-01-012022-10-05 Journal: Integrative cancer therapies [Category] SARS, 임상, [키워드] adherence age Behavior BMI Cancer concealed Controlled Controlled trial COVID-19 declined disease disease stage eligible patient Endometrial Cancer feasibility Health highest impacted Intervention intervention group majority measure nutrition occurred online questionnaire participant physical physical activity Randomized RCT recruited recruitment Registered retention Serious Adverse Event Support telehealth Treatment Trial usual care usual care alone [DOI] 10.1177/15347354211069885 PMC 바로가기 [Article Type] Randomized Controlled Trial