Human immune diversity: from evolution to modernity Reviews Published on 2021-11-182022-10-05 Journal: Nature Immunology [Category] 변종, 유전자 메커니즘, [키워드] age allele Analysis associations Defense Denisovan develop disease environmental exposure Evolution explain extreme genetic diversity Human Human immune system identify immune Interaction loci maintain mechanism Microbiome Migration Neanderthal Pathogens pathway plethora provide Sex variable Variation [DOI] 10.1038/s41590-021-01058-1 [Article Type] Reviews
Exposure to COVID-19 is associated with increased altruism, particularly at the local levelArticle Published on 2021-09-232022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] chose country COVID-19 COVID-19 pandemic Donor effort engage ENhance environmental exposure experiment exposure to had no Human behaviour identity influence International Italy Local National participant Psychology question Social evolution target theory [DOI] 10.1038/s41598-021-97234-2 PMC 바로가기 [Article Type] Article
Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic ReviewsReview Published on 2021-09-202022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] addressed adverse effect Analysis Breastfeeding case-control studies Clinical practice COVID-19 COVID-19 pandemic decrease Depression ectopic Effect environmental exposure Evidence Follow-up gestation period global public health Impact impacted indicated infected with SARS-CoV-2 Infection MOST mother Neonatal Neonatal Mortality Newborn observational studies outcome outcomes pandemic pregnancies Pregnancy pregnant women proportion reported review risk of infection SARS-CoV-2 SARS-COV-2 infection searched shown Stillbirth systematic review Transmission transmission of SARS-CoV-2 transmitted vertical vertical transmission Web of Science [DOI] 10.3390/v13091877 PMC 바로가기 [Article Type] Review
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin국소 차아염소산(HOCl)은 UV에 노출된 SKH-1 고위험 마우스 피부에서 염증성 유전자 발현 및 종양 발생 진행을 차단합니다Article Published on 2021-09-012022-09-11 Journal: Redox Biology [Category] SARS, 유전자 메커니즘, [키워드] addition Analysis AP-1 atopic dermatitis bioluminescent block blocked Cancer Carcinogenesis clinical evidence combinations condition consequence COVID-19 pandemic drinking water elicited environmental exposure example exposure to finding Gene Expression Gene expression analysis high risk HMOX1 HOCl hypochlorous acid Il19 Immunohistochemical analysis Inflammation Inflammatory inflammatory signaling investigated luciferase mice mimicking modulation molecular murine model NOS2 observation oxidative stress oxidizing Pathway-focused gene expression profiling performed progression psoriasis PTGS2 public health Radiation reconstructed released skin skin cancer Solar Solar UV radiation. Srxn1 Stress stress response subsequent Support suppressed suppression Swimming pool therapeutic therapeutic intervention These data TLR4 Topic topical transgenic ultraviolet water [DOI] 10.1016/j.redox.2021.102042 PMC 바로가기 [Article Type] Article
COVID-19 face masks: A new source of human and environmental exposure to organophosphate estersCOVID-19 안면 마스크: 유기인산 에스테르에 대한 인간 및 환경 노출의 새로운 출처Article Published on 2021-09-012022-09-11 Journal: Environment international [Category] SARS, 치료기술, [키워드] calculated carcinogenic Concentration concentrations Contamination COVID-19 Disposal economic cost environmental exposure Environmental pollution Face mask Face masks high risk highest Human Human exposure inhalation less lowest magnitude Mask Masks maximum microplastics organophosphate Organophosphate esters Plasticizers ranged risk Safe SARS-CoV-2 surgical tested threshold user Ventilated [DOI] 10.1016/j.envint.2021.106654 PMC 바로가기 [Article Type] Article
Transmission of COVID-19 and other infectious diseases in public washrooms: A systematic reviewReview Published on 2021-08-272023-06-17 Journal: The Science of the total environment [Category] MERS, SARS, [키워드] aerosol Bacterial and viral contamination environmental exposure Hand drying Public toilet SARS-CoV-2 [DOI] 10.1016/j.scitotenv.2021.149932 PMC 바로가기 [Article Type] Review
Environmentally-induced mdig contributes to the severity of COVID-19 through fostering expression of SARS-CoV-2 receptor NRPs and glycan metabolism환경으로 유발 된 MDIG는 SARS-COV-2 수용체 NRP 및 글리 칸 대사의 발현을 육성함으로써 COVID-19의 심각성에 기여한다.Research Paper Published on 2021-07-062022-09-10 Journal: Theranostics [Category] SARS, 변종, [키워드] Air pollution arsenic bronchial epithelial cell bronchial epithelial cells Cathepsins causative agent ChIP-seq contribute coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR cytokine Cytokine storm death decreased expression Depletion determinant determined by Effective strategies effective strategy elevated ENhance environmental exposure environmental factor environmental factors Epidemiological study epithelial cells Evidence expression expression of SARS-CoV-2 Genetic glycosylation induce Inflammation involved lysine mdig mediator metabolism Mortality Neanderthal neuropilin Neuropilin-1 NRP1 NRP2 oncogene patients Protein Proteins provided recent receptor reducing reported SARS-CoV-2 SARS-CoV-2 receptor SARS-CoV-2 receptors severity of COVID-19 suggested Symptom These data variant Viral viral infection β-coronavirus [DOI] 10.7150/thno.62138 PMC 바로가기 [Article Type] Research Paper
Repeated Exposure to Subinfectious Doses of SARS-CoV-2 May Promote T Cell Immunity and Protection against Severe COVID-19SARS-CoV-2의 하위 감염 용량에 대한 반복적인 노출은 T 세포 면역 및 심각한 COVID-19에 대한 보호를 촉진할 수 있습니다Opinion Published on 2021-05-222022-09-01 Journal: Viruses [Category] SARS, 변종, 진단, [키워드] absence COVID-19 COVID-19 infection COVID-19 infections detrimental disease severity dose environmental exposure Europe European country exposure to facial masking Factor Factors fomites heterogeneous Hospitalization immune immune protection immunization increasingly induce Inflammation Intervention intestinal tract long term low-dose memory T cells Mortality observation pandemic positive protection protective immunity provided reducing respiratory resulting SARS-CoV-2 SARS-CoV-2 dynamics SARS-CoV-2 particles SARS-CoV-2 variants SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells severe COVID-19 short term Spread starting suggested T cell T cell memory T cell responses T cells transmissible variant vaccination Vaccinations Viral viral particle virus widespread [DOI] 10.3390/v13060961 PMC 바로가기 [Article Type] Opinion
African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors associated with immunologic functions and environmental exposuresArticle Published on 2021-05-102022-10-04 Journal: Scientific Reports [Category] SARS, 바이오마커, 유전자 메커니즘, [키워드] affected African African American African Americans American Americans approach Biomarker can be used Cancer genomics cause CCL3L3 Cell cellular response Computational biology and bioinformatics COVID-19 COVID-19 pandemic Cytokines ENCODE environmental exposure environmental factors European expressed expression F8A2 Factor Gene Expression gene expression pattern Genetic genomic Genomics GSTM1 immunologic function implicated IMPROVE Inclusion Inflammation lung Metadata molecular molecular phenotype Mortality pathway Phenotypes physiological effect Population populations Precision Prevalence profile prognostic Protein reactive oxygen reactive oxygen specy risk RNA-sequencing SARS-CoV-2 Severe infection Stress therapeutic tissue Treatment Tumor up-regulated upregulated widespread xenobiotics [DOI] 10.1038/s41598-021-89224-1 PMC 바로가기 [Article Type] Article
Host barriers to SARS-CoV-2 demonstrated by ferrets in a high-exposure domestic setting높은 노출 국내 환경에서 흰 족제비에 의해 입증 된 SARS-CoV-2에 대한 호스트 장벽423 Published on 2021-05-042022-09-10 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Angiotensin-converting enzyme Antibody assays barrier circulating cleavage Contact coronavirus COVID-19 decrease demonstrated direct contact discrepancy Effect Efficiency environmental exposure Evidence evidence of experiment exposure to Factor ferret ferrets furin Genetic genetic factors genetics Host host adaptation hosts Human hypothese idea Infection Laboratory limit Mutation natural experiment natural infection no evidence of onward transmission positive predicted provide raising respiratory respiratory virus respiratory viruses risk S1/S2 cleavage site SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 susceptibility SARS-CoV-2 transmission second sequence severe acute respiratory syndrome Coronavirus shown Significance spike Support Surface glycoprotein susceptible symptomatic symptomatic COVID-19 symptomatic disease These data Transmission Viral viral adaptation Virology virus viruses while [DOI] 10.1073/pnas.2025601118 PMC 바로가기 [Article Type] 423