Modelling, prediction and design of COVID-19 lockdowns by stringency and durationArticle Published on 2021-08-032022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Applied mathematics approach caused change compartmental model complex Course COVID-19 death Effect effective strategy Epidemic Epidemiology Experimental models of disease Germany Government implementation infections lockdown lockdowns mathematical Modification observation predict social interaction spread of COVID-19 Support the disease the epidemic turn viral infection [DOI] 10.1038/s41598-021-95163-8 PMC 바로가기 [Article Type] Article
A modified age-structured SIR model for COVID-19 type virusesArticle Published on 2021-07-262022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] applied Applied mathematics Contact contribute COVID-19 disease spread distributions Effect Effectiveness Efficacy Epidemiology Experimental models of disease group less measure Measures Metrics mortality rate parameter parameters selected significant effect social contact Treatment USA vaccination virus Washington [DOI] 10.1038/s41598-021-94609-3 PMC 바로가기 [Article Type] Article
Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variantRNA- 의존성 RNA 폴리머 라제 및 스파이크 단백질에서 동시 돌연변이는 역학적으로 가장 성공적인 SARS-CoV-2 변이체로 나타났습니다.Article Published on 2021-07-012022-09-01 Journal: Scientific Reports [Category] SARS, 변종, 진단, [키워드] analysed aspartate Combination concurrent correlation country COVID-19 mortality D614G D614G mutation domain epidemiological epidemiologically Epidemiology Evolution Experimental models of disease explain facilitate GISAID glycine initial Mutation observé open P323L P323L mutation polymerase position Prevalence Protein Protein structure predictions pseudotyped replaced reported RNA-dependent RNA polymerase SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 variant speed Spike protein the SARS-CoV-2 the Spike transition variant variant of SARS-CoV-2 Viral viral infection Wuhan [DOI] 10.1038/s41598-021-91662-w PMC 바로가기 [Article Type] Article
Whole blood transfusion improves vascular integrity and increases survival in artemether-treated experimental cerebral malaria전혈 수혈은 혈관의 무결성을 개선하고 아르테메터 치료를 받은 실험적 뇌 말라리아에서 생존율을 증가시킵니다.Article Published on 2021-06-082024-08-08 Journal: Burma Med J [Category] 말라리아, [키워드] Experimental models of disease Infection malaria Neuro-vascular interactions [DOI] 10.1038/s41598-021-91499-3 PMC 바로가기 [Article Type] Article
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone systemArticle Published on 2021-04-232022-10-04 Journal: Nature Communications [Category] MERS, SARS, 임상, 진단, 치료기술, 치료법, [키워드] ACE2 acute tubular necrosis ameliorated angiotensin receptor blocker Blood cellular entry Coagulation COVID-19 COVID-19 cohort Diffuse alveolar damage disease driven by Experimental models of disease feature increase induce inhibitor involved lung MRI Multihormonal system disorders Oxygenation pathophysiological pathophysiology patients Prognosis pulmonary artery pressure RAAS reduce retrospective SARS-CoV-2 SARS-CoV-2 receptor severe COVID-19 System Thromboembolism viral infection [DOI] 10.1038/s41467-021-22713-z PMC 바로가기 [Article Type] Article
Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model햄스터 모델에서 SARS-CoV-2에 대한 Favipiravir 항바이러스 효능Article Published on 2021-03-192022-09-10 Journal: Nature Communications [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 치료제, [키워드] analyses animals anti-SARS-CoV-2 antiviral activity Antiviral effect antiviral efficacy antiviral molecule antiviral molecules clinical trial clinical trials comparable decrease determine dosage dose Drug development Effect Efficacy evaluated Evidence Experimental models of disease Favipiravir fitness Genetic genomes High dose highest dose human clinical trials humans in viral incorporation Infection infectious titer infectious titers initiated lack lung Lungs mechanism of action Mutation pharmacokinetic plasma drug reduction Repurposed drug Repurposed drugs required RNA viruses SARS-CoV-2 tested the disease Therapeutics Tolerance Toxicity Treatment variety Viral viral genome viral genomes viral infectivity [DOI] 10.1038/s41467-021-21992-w PMC 바로가기 [Article Type] Article
‘nAb’ the self-reactive activity in the COVID-19 combat'nAb' 코로나19 전투에서의 자가반응 활동Comment Published on 2021-03-022022-09-12 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 진단, [키워드] COVID-19 Experimental models of disease Infectious diseases [DOI] 10.1038/s41392-021-00518-2 PMC 바로가기 [Article Type] Comment
County-level longitudinal clustering of COVID-19 mortality to incidence ratio in the United StatesArticle Published on 2021-02-042022-10-04 Journal: Scientific Reports [Category] MERS, 치료제, [키워드] Analysis benefit Cancer Cardiomyopathy Cluster Clustering Clusters collected Complication country COVID-19 COVID-19 case COVID-19 epidemic COVID-19 mortality deaths diabete disorder exhibiting Experimental models of disease Factor group growth mixture model growth trajectory healthcare heart Hepatitis highest HIV/AIDS identify incidence Infectious diseases Mortality myocarditis potential risk public health resource risk factor Risk factors significantly the disease the United State Trajectories trajectory Tuberculosis was used [DOI] 10.1038/s41598-021-82384-0 PMC 바로가기 [Article Type] Article
Forecasting the long-term trend of COVID-19 epidemic using a dynamic modelArticle Published on 2020-12-032022-10-04 Journal: Scientific Reports [Category] MERS, 치료기술, 치료법, [키워드] Analysis applied approach Characteristics China confirmed case coronavirus disease country COVID-19 COVID-19 case COVID-19 epidemic COVID-19 outbreak COVID-19 transmission cumulative determine Effectiveness Epidemic epidemiological Epidemiology evaluated Experimental models of disease External validity FIVE Forecasting Health authority help Intervention machine learning model Modification outbreak overfitting pandemic parameter Population screening predict predicted previous study problems provided Region reported Risk factors SEIR Spread subject suggested Transmission viral infection virus [DOI] 10.1038/s41598-020-78084-w PMC 바로가기 [Article Type] Article
Fractional SIR epidemiological modelsArticle Published on 2020-11-302022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] assumption cells Complete Contact country COVID-19 disease disease transmission early phase Epidemic epidemiological Epidemiology Experimental models of disease France Germany groups Hypothesis incidence rate Infection Italy Local question Spain susceptible susceptible individuals Transmission two group widespread [DOI] 10.1038/s41598-020-77849-7 PMC 바로가기 [Article Type] Article