Progress and Challenges Toward Generation and Maintenance of Long-Lived Memory T Lymphocyte Responses During COVID-19Immunology Published on 2022-02-172022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] Activation acute respiratory syndrome B cell response CD4 CD8 cell-mediated immune challenge characterized consequence coronavirus coronavirus disease Coronavirus infection COVID-19 Cytokine storm dysfunction effective Generation identify Immunological memory Immunopathogenesis immunopathological imperative individual individuals Infection lymphocyte Lymphocytes lymphopenia maintenance memory memory response memory T cell response Neutrophils outbreak pandemic Progress reduced response SARS-CoV-2 SARS-COV-2 infection T cell T cell response T cells T memory cell Therapeutic strategies [DOI] 10.3389/fimmu.2021.804808 PMC 바로가기 [Article Type] Immunology
Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 ActivationArticle Published on 2022-02-152022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] Activation antiviral activity Apoptosis biological activity cause caused decrease diarrhea epidemic diarrhea ergosterol ergosterol peroxide Generation highlight Infection inhibit inhibitor inhibitory effect life cycle mitochondrial membrane potential morbidity and mortality NAC not affect p53 PEDV peroxide Porcine epidemic diarrhea virus Prevent Replication resulting ROS ROS production significantly Stage suppressed Suppressing therapeutic potential Vero Vero cells viral replication virus watery [DOI] 10.3390/v14020402 PMC 바로가기 [Article Type] Article
Hybrid Deep Feature Generation for Appropriate Face Mask Use Detection적절한 안면 마스크 사용 감지를 위한 하이브리드 딥 피처 생성Article Published on 2022-02-092022-09-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Accuracy Appropriate Classifier collected Compliance deep DenseNet201 detect detection face Face mask face mask detection feature Generation high accuracy hybrid hybrid feature selector hygiene Image IMPROVE indicate limit Mask Masked face Precaution problem real time ResNet101 resulting selected spread of COVID-19 Support support vector machine transfer learning Trial was used were used [DOI] 10.3390/ijerph19041939 PMC 바로가기 [Article Type] Article
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samplesResearch article Published on 2022-02-022022-10-05 Journal: Cell chemical biology [Category] COVID19(2023년), SARS, 변종, [키워드] Anticoagulant Anticoagulants anticoagulation aptamer bind clinically cofactor collected coronavirus disease COVID-19 COVID-19 patient disrupt factor V/Va feasibility Generation Hemostasis inhibitor Interaction interactions lack low molecular weight mechanism membranes nanomolar affinity Patient plasma protamine Protein protein inhibitor protein-membrane interaction regulate reveal reversed RNA synergy target therapeutic thrombosis Whole blood [DOI] 10.1016/j.chembiol.2022.01.009 [Article Type] Research article
In Vitro Evidence for the Role of Cytokine Storm in the Generation of Stent Thrombosis in COVID-19 PatientsCOVID-19 환자의 스텐트 혈전증 발생에서 사이토카인 폭풍의 역할에 대한 시험관 내 증거Editorial Published on 2022-02-012022-09-11 Journal: Cardiovascular revascularization medicine : includ [Category] COVID19(2023년), SARS, 치료기술, [키워드] COVID-19 Generation role Stent storm [DOI] 10.1016/j.carrev.2021.11.039 PMC 바로가기 [Article Type] Editorial
Levistolide A Inhibits PEDV Replication via Inducing ROS GenerationArticle Published on 2022-01-272022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] addition Affect Antiviral antiviral activity antiviral strategy cells cellular membrane Course dose-dependent manner epidemic diarrhea ER stress Generation indicated induce Inducing inhibit inhibiting inhibitor inhibitory effect less Levistolide A NAC PEDV Penetrating Porcine epidemic diarrhea virus Protein reactive oxygen species reactive oxygen specy Replication ROS ROS production sequence stimulate strain Strains suppress variant Viral RNA virus [DOI] 10.3390/v14020258 PMC 바로가기 [Article Type] Article
The Avon Longitudinal Study of Parents and Children – A resource for COVID-19 research: Antibody testing results, April – June 2021Data Note Published on 2022-01-242022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] addition ALSPAC Antibody Response Antibody test antibody test result Antibody testing birth cohort study Children of the 90s coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 vaccination dataset datasets Future Generation Health identify longitudinal longitudinal population natural infection nucleocapsid offspring online questionnaire pandemic parent participant population-based cohort positive pregnant women Public Health England questionnaire recruited released Research resource response serology Sociodemographic Spike protein supported tested vaccination women [DOI] 10.12688/wellcomeopenres.17294.2 PMC 바로가기 [Article Type] Data Note
The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 PatientsMedicine Published on 2022-01-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ADAMTS13 addition age aging Analysis analyzed Antigen axis binding activity BMI body mass index Coagulation Coagulopathy collagen collected conditions contribute contributed Corona COVID-19 COVID-19 negative cross-sectional elevated endothelial Endothelial dysfunction factor VIII Generation Health hospital Impact increases in increasing age individual obesity Older parameter Patient plasma plasmin populations positive reduced risk severity Simultaneous thrombin von Willebrand factor vWF [DOI] 10.3389/fmed.2021.817305 PMC 바로가기 [Article Type] Medicine
The impact of COVID-19 on fertility behaviour and intentions in a middle income countryResearch Article Published on 2022-01-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Affect affected comparison conceive conducted Contraception country COVID COVID-19 decrease disrupt Europe Generation Indicator individual Intention less male medium mental health pandemic pathway reduce reduced restriction survey the United State [DOI] 10.1371/journal.pone.0261509 PMC 바로가기 [Article Type] Research Article
Generation of Spike-Extracellular Vesicles (S-EVs) as a Tool to Mimic SARS-CoV-2 Interaction with Host CellsSARS-CoV-2와 숙주 세포의 상호 작용을 모방하는 도구로 스파이크-세포외 소포(S-EV) 생성Article Published on 2022-01-032022-09-12 Journal: Cells [Category] SARS, 진단, [키워드] Analysis anti-ACE2 antibody biogenesis bronchial epithelial cell Cell cells characterized clinical trials co-expressed coding Colchicine collected COVID-19 drugs embryonic kidney endothelial EVs expressing Extracellular vesicles generate Generation host-virus interaction internalization mechanism Microscopy MIMIC non-transfected reduced S1 and S2 Safe SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein significantly spike Spike protein subunits the SARS-CoV-2 therapeutic Vesicle virus [DOI] 10.3390/cells11010146 PMC 바로가기 [Article Type] Article