glycobiology – Page 3 – Communicable Diseases Research

Glycan-Based Flow-Through Device for the Detection of SARS-COV-2

SARS-COV-2의 검출을위한 글리 칸 기반 유량-스루 장치

Article

Published on 2021-10-112022-10-27
Journal: ACS Sensors [Category] Coronavirus, 변종, 진단, 치료기술, 치료제,

[키워드] alternatives antibody complement COVID-19 COVID-19 pandemic demonstrated detection develop Device diagnostic diagnostics disease spread Effectiveness faster flow-through Genetic glycans glycobiology gold Gold nanoparticle heat heat-inactivated individuals infectious agents Isolation lateral flow lentiviral LFD molecular mutants Nanoparticles nasal swabs Pandemics Patient polymers principle proof provide rapid diagnostics Recombinant spike protein recombinant spike proteins SARS-CoV-2 several variant several variants shown sialic acid Spike protein Spike proteins symptomatic individuals the spike protein Viral Viral load viral loads
[DOI] 10.1021/acssensors.1c01470 PMC 바로가기 [Article Type] Article

Afucosylated Plasmodium falciparum -specific IgG is induced by infection but not by subunit vaccination

감염에 의해 유도되지만 단백질 접합 백신에 의해 유도되지 않는 아푸코실화된 말라리아 원충 플라스모디움 파르시파룸 특이 IgG.

Article

Published on 2021-10-052024-08-08
Journal: Nature Communications [Category] 말라리아,

[키워드] antibodies glycobiology malaria Parasite host response Protein vaccines
[DOI] 10.1038/s41467-021-26118-w PMC 바로가기 [Article Type] Article

COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction

COVID-19는 내피 장벽 기능 장애를 직접 유도하는 히알루로난 단편을 생성합니다

Research Article

Published on 2021-09-082022-09-12
Journal: JCI Insight [Category] 진단,

[키워드] activity analyzed CD44 circulating circulation Clinical severity Complication contributing to coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical Critical illness damaged Degradation degrade disease dysfunction dysregulated endothelial Endothelial cell enzyme Enzymes Evidence exacerbating Extracellular matrix functions generate glycobiology glycocalyx glycosaminoglycan Hyaluronan hyaluronidase induce Inflammatory cytokine Injury moderate moderate to severe morbidity Organ failure pathologic pathology patients with COVID-19 plasma Protective provide pulmonary regulate released Sepsis Severity of disease significantly Vascular Vascular Biology Vascular injury
[DOI] 10.1172/jci.insight.147472 PMC 바로가기 [Article Type] Research Article

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting

Article

Published on 2021-08-032022-10-31
Journal: Communications Biology [Category] COVID-19,

[키워드] Analysis can be used Chalk Combination database Efficiency glycan glycobiology Greenland HPLC identification identify knowledge Laboratory LC-MS less mapping mass spectrometry MS3 peptide Protein protein digest quantitation resolved resolving power SARS-CoV-2 spike Structure time while
[DOI] 10.1038/s42003-021-02455-w PMC 바로가기 [Article Type] Article

Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors

Article

Published on 2021-06-092022-10-29
Journal: Scientific Reports [Category] COVID-19,

SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection

Article

Published on 2021-06-012023-06-13
Journal: The Journal of Clinical Investigation [Category] B형 간염, Fulltext,

[키워드] glycobiology Hepatitis immunology Immunotherapy Infectious disease
[DOI] 10.1172/JCI141965 PMC 바로가기

Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance

적혈구 만노스가 겸상적혈구 빈혈과 말라리아 저항성을 매개하는 식세포 리간드로 작용한다.

Article

Published on 2021-03-192024-08-08
Journal: Nature Communications [Category] 말라리아,

[키워드] glycobiology malaria Pattern recognition receptors Sickle cell disease
[DOI] 10.1038/s41467-021-21814-z PMC 바로가기 [Article Type] Article

How glycobiology can help us treat and beat the COVID-19 pandemic

글리코생물학이 COVID-19 전염병을 치료하고 극복하는 데 어떻게 도움이 되는지

Review

Published on 2021-02-042022-08-31
Journal: The Journal of Biological Chemistry [Category] 신약개발, 유전자 메커니즘, 진단, 치료제,

[키워드] ACE2, angiotensin-converting enzyme 2 acute respiratory syndrome acute respiratory syndrome coronavirus addition antibodies candidate drug candidate drugs coronavirus COVID-19 COVID-19 pandemic COVID-19 therapy Critical DC-SIGN, dendritic cell-specific ICAM-3-grabbing non-integrin Defense drug effective evaluate FDA-approved drugs Gal-3, galectin 3 glycan glycans glycobiology Glycosides help highlight Host HS, heparan sulfate IMP, importin IMPROVE Infection infection process infective inhibitors involved limit MBL, mannose-binding lectin MGL, macrophage galactose lectin pathology polysaccharides potential therapies probe producing Protein Proteins RBD, receptor-binding domain respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 suggested the SARS-CoV-2 therapeutic therapy treat Treatment Vaccines Viral protein Viral proteins virus
[DOI] 10.1016/j.jbc.2021.100375 PMC 바로가기 [Article Type] Review

Redirecting substrate regioselectivity using engineered ΔN 123 -GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens

엔지니어링된 ΔN 123 -GBD-CD2 가지형 수크라제의 기질 지역 선택성을 전환하여 S. flexneri 3a, 4a 및 4b 하프텐의 펜타사카라이드 반복 단위 생산

Article

Published on 2021-01-282024-07-30
Journal: Burma Med J [Category] 세균성이질,

[키워드] carbohydrates Enzymes glycobiology structural biology
[DOI] 10.1038/s41598-021-81719-1 PMC 바로가기 [Article Type] Article

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

Article

Published on 2020-11-042022-10-04
Journal: Cell Discovery [Category] 신약개발, 치료제,