Hospital admissions of acute cerebrovascular diseases during and after the first wave of the COVID-19 pandemic: a state-wide experience from AustriaShort Commentary Published on 2021-02-272022-10-29 Journal: Journal of Neurology [Category] COVID-19, MERS, SARS, [키워드] 95% CI acute cerebrovascular disease Acute stroke care Admission analysed Analysis bleeding cerebrovascular diseases corona virus disease 2019 coronavirus disease COVID-19 COVID-19 pandemic entire spectrum event First wave Frequency Hospital admission hospital admission rate Hospitalization hospitals ICH Intracranial haemorrhage investigated ischaemic stroke not affected not different Patient Poisson regression Public Hospital reduced remained Styria Thrombolysis Transient ischaemic attack Treatment [DOI] 10.1007/s00415-021-10488-8 PMC 바로가기 [Article Type] Short Commentary
Intracerebral Hemorrhage in COVID-19 Patients with Pulmonary Failure: A Propensity Score-Matched Registry StudyObservational Study Published on 2021-02-232022-10-04 Journal: Neurocritical care [Category] MERS, 임상, [키워드] acute respiratory distress age antiplatelet ARDS ARDS patients bleeding Case report cause conducted confounders COVID-19 COVID-19 group COVID-19 patient COVID-19 patients exhibited extracorporeal membrane oxygenation group hemorrhage ICH ICU in both group Intracerebral hemorrhage male no statistical difference non-COVID-19 group Older Patient patients with ARDS patients with moderate PCR-positive SARS-CoV-2 Propensity score pulmonary registry required Result retrospective risk SARS-CoV-2 severe ARDS significantly more single-center study SOFA score statistically supplementary material survival syndrome systemic anticoagulation therapeutic anticoagulation therapy thrombosis Ventilated VV-ECMO was performed [DOI] 10.1007/s12028-021-01202-7 PMC 바로가기 [Article Type] Observational Study
Coronavirus disease 2019 (COVID-19) can predispose young to Intracerebral hemorrhage: a retrospective observational studyObservational Study Published on 2021-02-192022-10-27 Journal: BMC Neurology [Category] COVID-19, MERS, [키워드] Admission affected age Arterial hypertension Central nervous system chronic arterial hypertension, hematoma. Clinical outcome CNS control group Coronavirus disease 2019 COVID COVID-19 COVID-19 negative COVID-19 positive patient Diabetes Mellitus discharge Encephalitis evaluated Factor Gender GOS hematoma hemorrhage Hospital stay hypertension ICH Intracerebral hemorrhage intraventricular lab Laboratory less Mental neurological no significant difference Occurrence other organ Partial Platelet positive patient prothrombin radiological reported Respiratory system Result retrospective scale Seizures Sex significant difference significantly lower smoking subject the disease the patient time two group two groups variable virus Volume WBC white younger patient [DOI] 10.1186/s12883-021-02109-8 PMC 바로가기 [Article Type] Observational Study
Coronavirus disease 2019 (COVID-19) can predispose young to Intracerebral hemorrhage: a retrospective observational studyObservational Study Published on 2021-02-192022-10-04 Journal: BMC Neurology [Category] 임상, [키워드] Admission affected age Arterial hypertension Central nervous system chronic arterial hypertension, hematoma. Clinical outcome CNS control group Coronavirus disease 2019 COVID COVID-19 COVID-19 negative COVID-19 positive patient Diabetes Mellitus discharge Encephalitis evaluated Factor Gender GOS hematoma hemorrhage Hospital stay hypertension ICH Intracerebral hemorrhage intraventricular lab Laboratory less Mental neurological no significant difference Occurrence other organ Partial Platelet positive patient prothrombin radiological reported Respiratory system Result retrospective scale Seizures Sex significant difference significantly lower smoking subject the disease the patient time two group two groups variable virus Volume WBC white younger patient [DOI] 10.1186/s12883-021-02109-8 PMC 바로가기 [Article Type] Observational Study
Characteristics of intracerebral haemorrhage associated with COVID-19: a systematic review and pooled analysis of individual patient and aggregate dataCOVID-19와 관련된 뇌내 출혈의 특성: 개별 환자 및 집계 데이터에 대한 체계적인 검토 및 통합 분석Original Communication Published on 2021-02-052022-09-10 Journal: Journal of Neurology [Category] MERS, SARS, 치료기술, [키워드] 95% CI age aggregate Analysis anticoagulation cause causes Characteristics Clinical management Clinical treatment clinician Cohort studies cohort study COVID-19 Data analysis high mortality ICH implication incidence Inpatient Inpatients Intracerebral haemorrhage IQR lobar mechanism median median age Mortality observation Patient patient data patients with SARS-CoV-2 Prevalence Result searched severe COVID-19 stroke supplementary material symptomatic systematic review the median therapeutic treated trials with COVID-19 [DOI] 10.1007/s00415-021-10425-9 PMC 바로가기 [Article Type] Original Communication
In vitro Dissolution Profile at Different Biological pH Conditions of Hydroxychloroquine Sulfate Tablets Is Available for the Treatment of COVID-19Molecular Biosciences Published on 2021-01-142022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] absorbance Acetate Agilent antimalarial applied Autoimmune diseases Biological buffer Concentration condition coronavirus Coronavirus disease 2019 COVID-19 DAD detection dissolution evaluate experiments globe harmonization HCl HCQ Hydroxychloroquine hydroxychloroquine sulfate ICH in vitro injection International Conference linear methanol parameter pH phosphate buffer Precision profile purified R 2 rheumatoid arthritis specificity Standard deviation sulfate sulfonic acid tablets Treatment validation Volume [DOI] 10.3389/fmolb.2020.613393 PMC 바로가기 [Article Type] Molecular Biosciences
Impact of COVID-19 on hospital admission of acute stroke patients in BangladeshResearch Article Published on 2021-01-132022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] Admission average changes in COVID-19 COVID-19 infections COVID-19 pandemic determine dropped expected female Frequency Hospital admission Hospitalization ICH Impact Injury Intracerebral hemorrhage investigated male management measure mechanism nasal swab neurologic neuroscience Older pandemic pathophysiologic Patient Poisson regression Poisson regression model positive reduction reduction in reductions in reperfusion Result Retrospective analysis RT-PCR SARS CoV-2 significantly statistically significant stroke study period subarachnoid hemorrhage the mean the patient Treatment venous were used [DOI] 10.1371/journal.pone.0240385 PMC 바로가기 [Article Type] Research Article
Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Acute Respiratory Distress Syndrome and Multi‐Organ FailurePharmacology Published on 2020-11-102022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activity acute lung injury acute respiratory distress adverse event AEs Affect Alpha Anti-inflammatory anti-inflammatory agents ARDS Cancer clinical Clinical course Clinical practice clinical study Compliance complications coronavirus disease COVID-19 COVID-19 patient Cytokine release syndrome dose-dependent dose-escalation double-blind evaluate examined exhibited failure GRADE growth factor healthy histopathological examination Human ICH include Inflammatory cytokine ingredient interleukin-6 intravenous Liver damage Model mortality rate mouse multi-organ dysfunction multi-organ failure Necrosis New niacinamide Patient patients phosphate placebo-controlled platform Pneumonia potent Preclinical Prevent profile Protective Pulmonary edema Randomized reduce respiratory response Riboflavin SAEs Safety safety profile Sepsis Serious Adverse Event Shock show Standard statistical analysis subject subjects survival syndrome Tolerability Treatment was performed [DOI] 10.3389/fphar.2020.594321 PMC 바로가기 [Article Type] Pharmacology
COVID-19 and Cerebrovascular Diseases: A Systematic Review and Perspectives for Stroke ManagementNeurology Published on 2020-11-052022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] 105 patients added Admission age Anticoagulant article association bleeding cardiovascular risk factors caused cerebrovascular collected conducted coronavirus COVID COVID-19 COVID-19 infection criteria critically ill patients D-dimer levels described etiology event Hemorrhagic Stroke Hyperactivation ICH Inflammatory Intracerebral hemorrhage intracranial hemorrhage intravenous large vessel male males manifestation mechanism multifactorial nine Patient patients patients with COVID-19 reported review SARS-CoV-2 selected Seven Sex statistical analysis stroke subarachnoid hemorrhage Symptoms systematic review the mean thrombosis treated Treatment venous was performed were excluded [DOI] 10.3389/fneur.2020.574694 PMC 바로가기 [Article Type] Neurology
Cerebrovascular events and outcomes in hospitalized patients with COVID-19: The SVIN COVID-19 Multinational RegistryObservational Study Published on 2020-09-302022-10-04 Journal: International Journal of Stroke [Category] MERS, 임상, [키워드] 95%CI Admission age All cerebrovascular diseases/stroke baseline Cerebral venous thrombosis cerebrovascular Cerebrovascular disease clinically Clustering Cohort cohort of patient coronavirus disease cortical country COVID-19 critically ill patients diagnosed evaluated event events female hemorrhage hospital hospitalized patient ICH in-hospital mortality in-hospital mortality rate incidence rate independent predictor Intervention intracranial hemorrhage laboratory-confirmed Lymphocyte count lymphocyte counts Male sex mechanism medical services mitigate Mortality mortality rate Older age outcome outcomes Patient patients Platelet predictor Primary outcome registry Result risk SARS-CoV-2 severity stroke thrombosis thrombotic event [DOI] 10.1177/1747493020959216 PMC 바로가기 [Article Type] Observational Study