Sophorolipid: a glycolipid biosurfactant as a potential therapeutic agent against COVID-19Review Published on 2021-12-142022-10-27 Journal: Bioengineered [Category] COVID-19, [키워드] addition anticancer Antiviral antiviral activity antiviral therapy attenuate being biosurfactant Cancer candidate caused COVID-19 COVID-19 in patients COVID-19 patient effective glycolipids immune response immunomodulator Infection inhibit microorganisms modulate nonpathogenic produced progression reduction in Research SARS-CoV-2 selected shown sophorolipid sophorolipids tension the cytokine storm the SARS-CoV-2 therapeutic Treatment unique variety Viral diseases viruses [DOI] 10.1080/21655979.2021.1997261 PMC 바로가기 [Article Type] Review
Sophorolipid: a glycolipid biosurfactant as a potential therapeutic agent against COVID-19Review Published on 2021-12-142022-10-27 Journal: Bioengineered [Category] Coronavirus, COVID-19, Fulltext, SARS, [키워드] addition anticancer Antiviral antiviral activity antiviral therapy attenuate being biosurfactant Cancer candidate caused COVID-19 COVID-19 in patients COVID-19 patient effective glycolipids immune response immunomodulator Infection inhibit microorganisms modulate nonpathogenic produced progression reduction in Research SARS-CoV-2 selected shown sophorolipid sophorolipids tension the cytokine storm the SARS-CoV-2 therapeutic Treatment unique variety Viral diseases viruses [DOI] 10.1080/21655979.2021.1997261 PMC 바로가기 [Article Type] Review
Sophorolipid: a glycolipid biosurfactant as a potential therapeutic agent against COVID-19Sophorolipid : COVID-19에 대한 잠재적 치료제로서의 glycolipid bioswermantantReview Published on 2021-12-142022-09-10 Journal: Bioengineered [Category] 신약개발, 치료제, [키워드] addition anticancer Antiviral antiviral activity antiviral therapy attenuate being biosurfactant Cancer candidate caused COVID-19 COVID-19 in patients COVID-19 patient COVID-19 patients cytokine Cytokine storm effective glycolipids immune response immunomodulation immunomodulator Infection inhibit Interfacial tension microorganisms modulate nonpathogenic produced progression reduction in Research SARS-CoV-2 selected shown sophorolipid sophorolipids surfactant tension the cytokine storm the SARS-CoV-2 therapeutic therapeutic agent Treatment treatment of COVID-19 unique variety Viral diseases viruses [DOI] 10.1080/21655979.2021.1997261 PMC 바로가기 [Article Type] Review
Anti-Inflammatory Effects of Immunostimulation in Patients with COVID-19 PneumoniaArticle Published on 2021-12-092022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Admission association Biomarker Blood cell supernatant cellular changes in Characteristics chemokines clinical conditions Control COVID-19 cytokine disease severity Effect gene expression pattern Genetic groups IFN-γ IL-4 immune response immunomodulation immunomodulator immunostimulation in vitro in-hospital mortality Inflammatory Influenza innate response intubation rate investigated molecular Neutrophil-to-lymphocyte ratio NLR not differ outcome outcomes Patient pidotimod plasma plasma concentration Pneumonia RCTs Recognition Respiratory failure SARS-CoV-2 Standard of care Standard-of-care systemic corticosteroid therapy toll like receptor Transcription treated upregulated viral infection Viral pneumonia virus were assessed with COVID-19 [DOI] 10.3390/jcm10245765 PMC 바로가기 [Article Type] Article
Intra- and inter-breed variation in immune response to acute and sub-chronic Salmonella infection and commercial immune-stimulant in two-layer breedsArticle Published on 2021-11-302024-09-07 Journal: Vet Med Sci [Category] 살모넬라증, [키워드] breed effect Gene Expression immune response immunomodulator Salmonella Enteritidis PMC 바로가기
Probiotics and Coronavirus disease 2019: think about the linkFull Papers Published on 2021-11-282022-10-28 Journal: The British Journal of Nutrition [Category] COVID-19, Fulltext, MERS, SARS, [키워드] Activation Adaptive immune response administer anti-inflammatory drug antiviral drugs candidate clinical benefits Coronavirus disease 2019 COVID-19 COVID-19 disease Critical case Cytokine storm disease Dysbiosis Effect Effects Gut gut microbiome gut microbiota hyper-inflammation immune dysregulation Immunity immunomodulator Microbiome moderate modulation morbidity and mortality mucosal Organisms pandemic pathogen pathophysiological Probiotics Safe Severe case tested translocation [DOI] 10.1017/S000711452000361X PMC 바로가기 [Article Type] Full Papers
Evaluation of the therapeutic regimen in COVID-19 in transplant patients: where do immunomodulatory and antivirals stand?이식 환자의 Covid-19에서의 치료 요법의 평가 : 면역 조절 및 항 바이러스는 어디에 서 있습니까?Research Published on 2021-11-222022-09-01 Journal: Virology Journal [Category] MERS, SARS, 진단, 치료제, [키워드] administration Adverse reactions age analyzed Anti-viral anti-viral drug Antiviral bacterial coinfections cardiovascular choice clinical clinical complication clinical complications conducted Coronavirus disease 2019 Course COVID-19 COVID-19 diagnosed patient COVID-19 diagnosed patients COVID-19 patients evaluate evaluated hospital Hospitalization Hospitalized immunocompromised status immunomodulator immunomodulatory imperative information intensive care intensive care unit Iran kidney less liver Lopinavir Lopinavir/ritonavir management medication mortality rate mortality rates Multiple regression analysis no significant difference Organ transplant p value Patient patients Positive test recipient reduce regimen regimens Remdesivir Result Retrospective study Ritonavir RT-PCR SARS-CoV-2 RT-PCR significant difference significantly solid-organ transplant survival the patient therapeutic Tocilizumab Transplant treated treating COVID-19 patient Treatment [DOI] 10.1186/s12985-021-01700-2 PMC 바로가기 [Article Type] Research
Immunomodulation and Regenerative Capacity of MSCs for Long-COVIDLong-COVID에 대한 MSC의 면역 조절 및 재생 능력Review Published on 2021-11-172022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome ARDS Capacity clinical clinical trial clinical trials Cytokine storm death edema Effect effective drug effective drugs eventually death immunomodulation immunomodulator include Inflammation long-COVID lung lung injuries Lung injury mesenchymal stem cell Mesenchymal stem cells MSC MSCs Mutation patients with COVID-19 Post-COVID-19 patients promote provided Pulmonary edema reduce regeneration regenerative regenerative properties respiratory distress SARS-CoV-2 virus severity syndrome the disease the SARS-CoV-2 virus therapy Treatment Trial Usage [DOI] 10.3390/ijms222212421 PMC 바로가기 [Article Type] Review
Estimating the viral loads of SARS-CoV-2 in the oral cavity when complicated with periapical lesionsResearch Published on 2021-11-082022-10-28 Journal: BMC Oral Health [Category] COVID-19, Fulltext, MERS, SARS, [키워드] ACE-2 acute respiratory syndrome addition Affect Analysis caused clinical sample Coronavirus-2 correlation COVID-19 Critical downregulation entry of SARS-CoV-2 enzyme Express expression expression of SARS-CoV-2 Fatty acid fatty acids gas chromatography–mass spectrometry Gene Expression Genes granuloma healthy highest host cells IL-6 immunomodulator immunomodulatory effect in viral indicated Infection Infection load Inflammation knowledge lesion lesions Major mammalian cell metabolite oleic acid oral lesions overexpression receptor receptors reduce required Result S protein SARS-CoV-2 SARS-COV-2 infection significantly susceptible the binding affinity the healthy tissue TMPRSS2 transmembrane serine protease unique upregulated upregulation viral infection Viral load viral loads viral replication was determined was performed was tested [DOI] 10.1186/s12903-021-01921-5 PMC 바로가기 [Article Type] Research
Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19감염성 질환 치료를 위한 면역조절제로서의 약물 전달 시스템: COVID-19와 관련성Review Published on 2021-11-012022-09-11 Journal: Advanced drug delivery reviews [Category] MERS, 신약개발, 진단, 치료제, [키워드] Activation adaptive approach approaches blocking agents cellular Coagulation complement complex complex interplay COVID-19 damage drug delivery system drug delivery systems endothelial Endothelium global pandemic identify immune Immune cell immune cells Immune suppression immunomodulator immunomodulatory IMPROVE improvement Inflammasome inflammasomes Inflammation Interaction involved limit moderate to severe molecular nanomedicine not limited outcome pathogen clearance pathology pathophysiology Patient patients with moderate Prognosis Relevance SARS-CoV-2 severe COVID-19 survival rates Therapeutic approach therapeutic approaches therapeutic option therapy tissue damage [DOI] 10.1016/j.addr.2021.113848 PMC 바로가기 [Article Type] Review