Prognostic Impact of Bronchoalveolar Lavage Fluid Galactomannan and Aspergillus Culture Results on Survival in COVID-19 Intensive Care Unit Patients: a Post Hoc Analysis from the European Confederation of Medical Mycology (ECMM) COVID-19-Associated Pulmonary Aspergillosis StudyObservational Study Published on 2022-04-202022-10-05 Journal: Journal of Clinical Microbiology [Category] 임상, [키워드] 95% CI adjusted Analysis aspergillosis Aspergillus association BALF Biomarker Bronchoalveolar lavage fluid can be used CAPA Combination conducted confidence interval coronavirus disease COVID-19 Critically ill patient Culture develop diagnosed enrolled European final multivariable model galactomannan galactomannan. GM hazard ratio heterogeneity Impact increasing age independent independent predictor intensive care unit lavage malignant disease Mortality MOST multicenter mycology optical Patient positive prognostic Prognostic value pulmonary Result survival with COVID-19 [DOI] 10.1128/jcm.02298-21 PMC 바로가기 [Article Type] Observational Study
Determinants of persistence of symptoms and impact on physical and mental wellbeing in Long COVID: A prospective cohort studyLong COVID에서 증상의 지속성과 신체적 정신적 웰빙에 미치는 영향의 결정 요인: 전향적 코호트 연구Article Published on 2022-04-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Admission advanced age analyzed breathlessness consequence contribute COVID COVID-19 COVID-19 patients determinant Duration fatigue female gender Health Hospital admission Hospitalized ICU identify independent predictor independent predictors Long Long COVID males Mental Patient persistence physical Physical health Population predictor predictors prospective cohort prospective cohort study Psychological distress residual Residual symptoms risk factor Risk factors Symptom Symptom persistence. symptomatic Symptoms the median were assessed [DOI] 10.1016/j.jinf.2022.02.003 PMC 바로가기 [Article Type] Article
Clinical features and major bleeding predictors for 161 fatal cases of COVID-19: A retrospective observational studyObservational Study Published on 2022-04-012022-10-05 Journal: Bosnian Journal of Basic Medical Sciences [Category] 임상, [키워드] Acute kidney injury age ARDS C-reactive protein change Characteristics clinical collected Complication complications correlation COVID-19 CRP D-dimer Diabetes Mellitus died Disseminated intravascular coagulation events feature hemoglobin hemoptysis Hospitalization hypertension In-hospital in-hospital complication in-hospital complications independent predictor INR intensive care International Laboratory laboratory parameter liver LMWH low molecular weight major bleeding male median age myocardial injury non-survivor normalized parameter Patient patients with COVID-19 Platelet predictor proportion regression analysis retrospective Retrospective study risk factor suffered the patient were recorded with COVID-19 [DOI] 10.17305/bjbms.2021.6577 PMC 바로가기 [Article Type] Observational Study
Clinical features and independent predictors for recurrence of positive SARS-CoV-2 RNA: A propensity score-matched analysis양성 SARS-CoV-2 RNA의 재발에 대한 임상적 특징 및 독립적 예측인자: 성향 점수 일치 분석Article Published on 2022-04-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% CI 95% confidence interval activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Analysis Blood borderline categorical variable CD3 CD4 chlorine clinic clinical confounding factors coronavirus count COVID-19 COVID-19 patient cured determine discharged elevated Factor feature hospital independent independent predictor independent predictors independent risk factor independent risk factors Logistic regression analysis marker multivariate multivariate logistic regression multivariate logistic regression analysis Odds ratio Patient positive Potassium propensity score matching prothrombinase Public recurrence regression analysis RNA SARS-CoV-2 SARS-CoV-2 RNA sensitivity analysis serum severe acute respiratory syndrome Coronavirus statistical statistically significant virus was used with COVID-19 [DOI] 10.1002/jmv.27450 PMC 바로가기 [Article Type] Article
C-reactive protein cut-off for early tocilizumab and dexamethasone prescription in hospitalized patients with COVID-19COVID-19로 입원한 환자의 초기 토실리주맙 및 덱사메타손 처방에 대한 C 반응성 단백질 차단Article Published on 2022-03-282022-09-12 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, 치료법, 치료제, [키워드] 30-day mortality rate Admission age Analysis Anti-inflammatory therapy C-reactive protein C-reactive protein (CRP CRP cut-off defined Dexamethasone evaluated help hospital hospitalized patient independent predictor Infection inflammatory activity intensive care Interaction IQR males median Mortality Multivariate analysis outcome Patient performed Primary outcome receiving reduction in reduction in mortality SARS-CoV-2 stratified Tocilizumab variable viral replication with COVID-19 [DOI] 10.1038/s41598-022-08882-x PMC 바로가기 [Article Type] Article
Characteristics of lymphocyte subsets and cytokine profiles of patients with COVID-19COVID-19 환자의 림프구 하위 집합 및 사이토카인 프로필의 특성Article Published on 2022-03-282022-09-11 Journal: Virology Journal [Category] 변종, 치료기술, [키워드] Abnormalities age Analysis analyzed AUC B cells Care CD19 CD3 CD4 CD8 Cell Chongqing clinical Clinical and laboratory data coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical cutoff value cytokine cytokine profile Cytokines diabetes Diabetes Mellitus enrolled evaluate Factor Hospital admission ICU ICU admission ICU patient ICU Patients IL-6 independent predictor independent predictors Infection interleukin laboratory data Logistic regression Logistic regression analysis lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes lymphopenia Most patients multivariate multivariate logistic regression analysis mutant natural killer no statistical difference No statistical differences non-ICU non-ICU patient non-ICU patients Odds ratio Patient patients patients with COVID-19 peripheral lymphocyte Predictive Predictive value receiver operating characteristic ROC ROC Curve selected sensitivity severe disease severe group severity severity of COVID-19 significantly significantly higher specificity statistical differences subset T cell T cells tested the disease Three Gorge Three Gorges treated university virus infection was used wild-type virus [DOI] 10.1186/s12985-022-01786-2 PMC 바로가기 [Article Type] Article
BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant RecipientsBNT162b2 3차 부스터 용량은 신장 이식 수혜자의 RBD IgG 및 중화 항체 모두에 의해 평가된 체액 반응을 상당히 증가시킵니다Article Published on 2022-03-212022-09-11 Journal: Transplant International [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Allograft antibody Antibody Response BNT162b2 BNT162b2 vaccine booster COVID-19 COVID-19 vaccine develop Diabetic diabetic nephropathy Dilution domain dose effective ESRD geometric mean geometric mean titer geometric mean titers GMT GMTs group had no humoral Humoral response IgG Immunosuppression increase independent predictor independent predictors mycophenolic acid negative and positive nephropathy Neutralizing antibodies neutralizing antibody non-responder non-responders of BNT162b2 Patient positive predictor pseudo-virus RBD RBD IgG Receptor-binding domain recipient recipients remained renal Renal transplantation Responder responders response response rate SARS-CoV-2 secondary to seroconverted significant increase stratified systemic systemic AEs the vaccine Transplant Vaccine were recorded [DOI] 10.3389/ti.2022.10239 PMC 바로가기 [Article Type] Article
Risk of Seven-Day Worsening and Death: A New Clinically Derived COVID-19 ScoreObservational Study Published on 2022-03-202022-10-04 Journal: Viruses [Category] SARS, 임상, [키워드] age analyzed C-reactive protein Clinical score Cohort collected composed COVID-19 cutoff value death demonstrated develop enrolled Fatality rate First wave Hospitalized identify independent predictor Infection lactate dehydrogenase multivariable analysis Negative predictive value Neutrophil-to-lymphocyte ratio New NPV outcome oxygen saturation pandemic patients hospitalized patients with SARS-CoV-2 Positive predictive value PPV predict Predictive prognostic prognostic score recognize retrospective risk risk factor risk of death risk of worsening. SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patients score second wave sensitivity specificity subject subjects the median validation cohort variable were used worsening [DOI] 10.3390/v14030642 PMC 바로가기 [Article Type] Observational Study
A sigh of relief: vaccine-associated hypermetabolic lymphadenopathy following the third COVID-19 vaccine dose is short in duration and uncommonly interferes with the interpretation of [ 18 F]FDG PET-CT studies performed in oncologic patients안도의 한숨: 세 번째 COVID-19 백신 접종 후 백신 관련 대사과다 림프절병증은 지속 기간이 짧고 드물게 종양 환자에서 수행된 [ 18 F]FDG PET-CT 연구의 해석을 방해합니다Article Published on 2022-03-012022-09-11 Journal: European Journal of Nuclear Medicine and Molecular [Category] SARS, 치료기술, [키워드] administration age BMI BNT162b2 BNT162b2 vaccine correlation COVID-19 COVID-19 vaccine dose dose administration doses GRADE High-grade Humoral immunity immune response incidence incidence of COVID-19 independent predictor independent predictors interfere Interpretation IQR less Lymphadenopathy median time multivariable logistic regression obese obese patients Older Oncologic imaging Patient patients performed PET-CT reported separation time interval unlikely vaccination vaccine dose were recorded [DOI] 10.1007/s00259-021-05579-7 PMC 바로가기 [Article Type] Article
Prognostic Markers in Hospitalized COVID-19 Patients: The Role of IP-10 and C-Reactive Protein입원한 COVID-19 환자의 예후 마커: IP-10 및 C-반응성 단백질의 역할Observational Study Published on 2022-02-282022-09-10 Journal: Disease Markers [Category] MERS, 바이오마커, 임상, [키워드] Admission Analysis analyzed Asymptomatic AUC baseline baseline characteristics Biomarker C-reactive protein C-reactive protein (CRP characteristic chemokine clinical condition clinical conditions clinical decision clinically cohort study Concentration Course COVID-19 CRP cytokine death discharge disease disease onset disease severity driving enrolled Evolution expected growth factor heterogeneous Hospital stay Hospitalization Hospitalized hospitalized COVID-19 patients identify immunological independent predictor independent predictors intensive care intensive care unit IP-10 Italy Laboratory Laboratory tests majority Manifestations moderate moderate to severe Multivariate analysis outcome pandemic Patient performed predict prospective cohort study responsible Result ROC role SARS-CoV-2 SARS-CoV-2 positive patient sensitivity serum serum concentrations specificity Stratification trajectory worsening [DOI] 10.1155/2022/3528312 PMC 바로가기 [Article Type] Observational Study