Differential drivers of intraspecific and interspecific competition during malaria-helminth co-infectionarticle Published on 2021-08-312024-09-01 Journal: Parasitology [Category] 말라리아, [키워드] Co-infection dose dependence Hookworm infectious dose malaria within-host [Article Type] article
Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19혈청 전환 및 발열은 흡입 COVID-19의 비인간 영장류 모델에서 용량 의존적Research Article Published on 2021-08-232022-09-10 Journal: PLoS Pathogens [Category] MERS, 변종, 치료기술, [키워드] 95% CI aerosol transmission age animals Asymptomatic baseline Clinical sign Clinical signs Comorbidities COVID-19 dependent on develop disease disease transmission dose dose-dependent Efficacy Evidence exposure dose Factor Factors Fever healthy humans immune response Infection infectious infectious dose inhalation limit masking median nasopharyngeal oropharyngeal swabs Probability provided public health measure public health measures resulting SARS-CoV-2 SARS-COV-2 infection Seroconversion significantly lower social distancing Spread subsequent subset TCID the median Therapeutics These data transmission of SARS-CoV-2 Vaccine Ventilation Viral viral variant virus while [DOI] 10.1371/journal.ppat.1009865 PMC 바로가기 [Article Type] Research Article
Efficacy of “Essential Iodine Drops” against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)중증 급성 호흡기 증후군-코로나 바이러스 2 (SARS-COV-2)에 대한 "필수 요오드 방울"의 효능Research Article Published on 2021-07-092022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료제, [키워드] 1:1 aerosolization aqueous solution ATCC CCID Cell Cell culture complex controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients CPE Cytopathic effect demonstrated Dilution drop effective end-point dilution Essential evaluated fulvic acid in vitro infecting infectious dose intranasal intranasally Iodine pandemic povidone-iodine Prevent quantified reduce reduced reducing reductions in respiratory respiratory droplet Respiratory droplets Result room temperature SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 viral SARS-CoV-2 virus Severe acute respiratory syndrome Spread temperature titre titres Vero Viral Viral load virucidal virus virus stock viruses was reduced was tested [DOI] 10.1371/journal.pone.0254341 PMC 바로가기 [Article Type] Research Article
Multiplex Real-Time Reverse Transcription PCR for Influenza A Virus, Influenza B Virus, and Severe Acute Respiratory Syndrome Coronavirus 2인플루엔자 A 바이러스, 인플루엔자 B 바이러스 및 중증 급성 호흡기 증후군 코로나바이러스 2에 대한 다중 실시간 역전사 PCRResearch Published on 2021-07-012022-09-10 Journal: Emerging Infectious Diseases [Category] 유전자 메커니즘, 치료기술, [키워드] 2019 novel coronavirus disease acute respiratory infections acute respiratory syndrome acute respiratory syndrome coronavirus cause caused coronavirus coronavirus 2 coronavirus disease Coronaviruses COVID-19 Culture detect diagnostic differentiation drug Emergency use authorization Flu SC2 Multiplex food identify in vitro increase infectious dose Influenza influenza A influenza A virus influenza B influenza B virus Influenza virus influenza viruses multiplex Multiplex assay outbreak pandemic pathogen Pathogens PCR reaction real-time RT-PCR resources respiratory respiratory infections respiratory virus RNA SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Surveillance Symptom tissue tissue culture US Food and Drug Administration virus viruses zoonoses [DOI] 10.3201/eid2707.210462 PMC 바로가기 [Article Type] Research
SARS-CoV-2 Production in a Scalable High Cell Density BioreactorArticle Published on 2021-06-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome addition animal component-free approved bioreactor carrier CelCradle Cell Cell culture cells conditions coronavirus COVID-19 Culture demonstrated density ENhance highest IMPROVE Inactivated vaccine Infection infectious dose log medium multiplicity of infection packed-bed pandemic per day Post-infection produced Production reported SARS-CoV-2 scalable bioreactor Seven severe acute respiratory syndrome coronavirus 2 TCID temperature tested tissue trypsin Vaccine vaccine production Vero Vero cells virus virus production virus spread viruses Volume while WHO whole virus vaccine [DOI] 10.3390/vaccines9070706 PMC 바로가기 [Article Type] Article
Protective Effect of Zinc Oxide and Its Association with Neutrophil Degranulation in Piglets Infected with Porcine Epidemic Diarrhea VirusResearch Article Published on 2021-06-232022-10-29 Journal: Oxidative Medicine and Cellular Longevity [Category] Coronavirus, [키워드] Administered administration affected analyses Analysis anti-inflammatory effect Antiviral average biological process caused Colon Concentration Culture determine diarrhea differentially expressed gene dismutase dose drug Effect epidemic diarrhea Gene ontology growth histologic IL-1 β IL-6 IL-8 implication IMPROVE indicated Infection infectious dose Inflammation inhibit inoculated intestinal intestine lesions mechanism metabolism Microarray morphology neutrophil degranulation oxidative stress Oxide pathway PEDV peroxidase plasma Prevent Protein proteomic randomly divided redox status reduce reduction Replication rescued Result shown significantly increased small intestine TCID three group tissue treat Treatment villus Viral load virus were recorded Zinc zinc oxide [DOI] 10.1155/2021/3055810 PMC 바로가기 [Article Type] Research Article
A Cytopathic Effect-Based Tissue Culture Method for HCoV-OC43 Titration Using TMPRSS2-Expressing VeroE6 CellsResearch Article Published on 2021-05-122022-10-30 Journal: mSphere [Category] Coronavirus, [키워드] 50% tissue culture infectious dose assay Accuracy antibody Cell cell entry cell lines cells complex contribute coronavirus costly CPE Culture culture supernatant Cytopathic effect early stage expressing HCoV-OC43 Human human coronavirus immunoperoxidase indicated infected cell Infection infectious dose IPA observation protease provide Research serine 2 staining substrates TCID time-consuming tissue titration TMPRSS2 transmembrane VeroE6 cell viral kinetics viral titer virus [DOI] 10.1128/mSphere.00159-21 PMC 바로가기 [Article Type] Research Article
A guideline to limit indoor airborne transmission of COVID-19416 Published on 2021-04-272022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS, [키워드] activities acute respiratory syndrome aerosol droplet Airborne transmission arise available data build case study Contact tracing coronavirus COVID-19 dimension disease transmission distributions estimate event Face mask Face masks facilitate filtration indoor safety guideline infectious aerosol infectious dose limit magnitude New coronavirus new virus offer outbreak pandemic status Particular PROTECT provided reduced respiratory activity respiratory aerosols respiratory droplet risk rule SARS-CoV SARS-CoV-2 coronavirus Significance social distancing thought Transmission Ventilation virions while [DOI] 10.1073/pnas.2018995118 PMC 바로가기 [Article Type] 416
The initial infectious dose of SARS-CoV-2 and the severity of the disease: possible impact on the incubation periodSpecial Report Published on 2021-04-142022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] acute respiratory syndrome Bacterial infections clinical coronavirus COVID-19 cytokine response Cytokine storm danger-associated molecular pattern decrease doses Immunopathogenesis Incubation period Infection infectious dose Inflammation Influenza initial initial infectious dose MERS Pathogenesis progression SARS-CoV-2 severe disease severity the disease therapy Variation Viral load [DOI] 10.2217/fvl-2020-0330 PMC 바로가기 [Article Type] Special Report
Role of high-dose exposure in transmission hot zones as a driver of SARS-CoV-2 dynamicsLife Sciences–Mathematics interface Published on 2021-03-312022-10-30 Journal: Journal of the Royal Society Interface [Category] COVID-19, SARS, [키워드] assumption characterized Community community transmission COVID-19 disease dose effective epidemiological Epidemiology Europe High-dose infected individuals Infection infectious dose Intervention lack lockdowns low-dose majority mathematical Mild occur plants predicted reducing role SARS-CoV-2 SARS-CoV-2 dynamics severe disease Spread suppress targeted intervention Transmission transmitted USA virus virus spread virus transmission with mild disease zone [DOI] 10.1098/rsif.2020.0916 PMC 바로가기 [Article Type] Life Sciences–Mathematics interface