isolates – Page 3 – Communicable Diseases Research

Persistence of infectious SARS-CoV-2 particles for up to 37 days in patients with mild COVID-19

경증 COVID-19 환자에서 최대 37일 동안 전염성 SARS-CoV-2 입자 지속

Article

Published on 2022-07-012022-09-11
Journal: Allergy [Category] COVID19(2023년), SARS, 치료기술,

Increased Abundance of Achromobacter xylosoxidans and Bacillus cereus in Upper Airway Transcriptionally Active Microbiome of COVID-19 Mortality Patients Indicates Role of Co-Infections in Disease Severity and Outcome

COVID-19 사망률 환자의 상부 기도에서 증가된 Achromobacter xylosoxidans 및 Bacillus cereus는 질병 심각도 및 결과에서 공동 감염의 역할을 나타냅니다.

Article

Published on 2022-06-292022-09-11
Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] abundance Achromobacter Actinomyce Alter Analysis Antibiotic therapy approaches Bacillus cereus Bacterial bacterial species bacterial specy Care clinical manifestation Co-infection complementary complications of COVID-19 contribute COVID-19 COVID-19 patient current disease disease outcome disease pathology disease severity disease sub-phenotype Exacerbation Factor feature functional groups highlight Holo-Seq hospital host-pathogen interactions Increased Inflammatory response Inflammatory responses Integrative analysis investigated involved isolate isolates Leptotrichia mechanism Medical care metabolic pathways microbe microbial Mild mild COVID-19 patients moderate modulate modulating Mortality nasopharyngeal nasopharyngeal RNA outcome parameters pathogen pathogen genomics Patient patients phenotype Phenotypes Phylogenetic analysis progression provide question recovered patient recovered patients reported respiratory virus respiratory virus oligo panel (RVOP) role SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 pathogenesis Sequencing severe COVID-19 severe disease severity susceptibility Symptoms the disease the patient transcript transcriptionally transcriptionally active microbial isolates. Transmissibility upper vaccination variants variants of concern VoC window
[DOI] 10.1128/spectrum.02311-21 PMC 바로가기 [Article Type] Article

Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other Lineages

COVID-19 환자의 비인두 샘플에서 SARS-CoV-2 분석은 다른 계통과 관련하여 우려되는 변이체의 성장 특성을 배치하여 인구 변이 및 다양한 표현형을 보여줍니다

Article

Published on 2022-06-292022-09-11
Journal: mSphere [Category] COVID19(2023년), SARS, 변종,

[키워드] A549 cells Alpha amplified Beta Beta variant Biology biology of SARS-CoV-2 causative agent Cell Cell culture cell line cells change characterized clinical isolates clinical samples concern Context coronavirus COVID-19 Delta disease effective Evolution genetic diversity genetics genome sequence genomic global pandemic growth growth kinetics hACE2 hospitalized patient hospitalized patients humans immune evasion increased risk indicated Infection isolate isolates less Lineage minor minor genomic variants morbidity Mortality Nasopharyngeal swab nasopharyngeal swabs New no difference not different omicron Other other coronaviruses other variant other variants pandemic patients pattern planet Population Population dynamics Population genetics Postinfection preserved property Research RNA RNA sequencing Sample SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequence several variants Spread suggested Transmission vaccination Vaccine Variability variant variants variants of concern variants of SARS-CoV-2 Variation Vero E6 Vero E6 cell VERO E6 cells virus Virus evolution VoC VOCs widespread with COVID-19
[DOI] 10.1128/msphere.00913-21 PMC 바로가기 [Article Type] Article

Genome sequence diversity of SARS-CoV-2 obtained from clinical samples in Uzbekistan

우즈베키스탄의 임상 샘플에서 얻은 SARS-CoV-2의 게놈 서열 다양성

Article

Published on 2022-06-272022-09-11
Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha Amino acid amino acid substitution annotation association change clade clades clinical isolates clinical sample Cluster coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity D614G Deleterious Deletion Delta Denmark disease severity evidenced Evolution female followed by genetic diversity Genome Genomic analysis genomic change Genotype help Identified isolate isolates male Missense Missense mutation Missense mutations Mutation Nextstrain NSP Nsp12 nsp13 Nsp3 nsp4 NSP6 nucleotide Open reading frame ORF ORF7a Pathogenesis PCR-positive patient Protein reading regions Research Russia SARS-CoV SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants sequence severe acute respiratory syndrome Coronavirus severity significantly SNP SNPs subclade Substitution synonymous Tashkent the Spike two group two groups USA variant variants Variation WGS whole genome sequence with COVID-19
[DOI] 10.1371/journal.pone.0270314 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Delta variant isolates from vaccinated individuals

SARS-CoV-2 Delta 변이체는 예방접종을 받은 개인에서 분리됩니다.

Article

Published on 2022-06-042022-09-11
Journal: BMC Genomics [Category] COVID19(2023년), SARS, 변종,

[키워드] addition Affect circulating Cluster collected conformational change COVID-19 cytosolic Delta Delta B.1.617.2 delta variant Disruption genetic diversity Genome sequencing Genomic analysis hydrophobic immune evasion induce isolate isolates Lineage Mutation mutations Non-synonymous mutation Nsp15 Nsps ORF1 ORF1b ORF7a ORF8 Oxford Nanopore MinION polar position positive sample predominant premature stop codon Protein SARS-CoV-2 SARS-CoV-2 delta SARS-CoV-2 virus SARS-CoV-2 viruses side chain Spike protein the spike protein transmembrane protein Transmissibility Transport vaccinated individual vaccinated individuals Vaccine variant variant of concern virus was performed Whole genome sequencing
[DOI] 10.1186/s12864-022-08652-z PMC 바로가기 [Article Type] Article

SARS-CoV-2 Continuous Genetic Divergence and Changes in Multiplex RT-PCR Detection Pattern on Positive Retesting Median 150 Days after Initial Infection

SARS-CoV-2 지속적인 유전적 분화 및 초기 감염 후 150일의 양성 재검사 중앙값에 대한 다중 RT-PCR 검출 패턴의 변화

Article

Published on 2022-06-022022-09-11
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제,

[키워드] accumulate amplification Amplification assay analyzed being Chain Reaction change Clinical diagnosis Continuous COVID-19 COVID-19 pandemic Day detection diagnostic Divergence envelope gene epicenter Epidemiology evaluated Evolution Frequency gene amplification Genetic genetic divergence genomes highlight hotspot identify in viral independent Infection initial isolate isolates lab molecular molecular evolution multiplex Multiplex RT-PCR Mutation next generation sequencing NGS Nucleocapsid gene Patient pattern performed polymerase chain polymerase chain reaction positive primer probe Region Reinfection reverse transcription reverse transcription polymerase chain reaction RT-PCR SARS-CoV-2 SARS-CoV-2 RNA specimen Spectrum target tested utility Viral viral genome viral genomes Viral variants virus WGA whole genome
[DOI] 10.3390/ijms23116254 PMC 바로가기 [Article Type] Article

Effectiveness of a COVID-19 Additional Primary or Booster Vaccine Dose in Preventing SARS-CoV-2 Infection Among Nursing Home Residents During Widespread Circulation of the Omicron Variant – United States, February 14-March 27, 2022

2022년 2월 14일-3월 27일, 미국, 2022년 2월 14일-3월 27일, 미국, 2022년 2월 14일-3월 27일

Article

Published on 2022-05-062022-09-11
Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종,

[키워드] 95% CI accounted Ad26 analyzed B.1.1.529 BNT162b2 booster dose booster doses Booster vaccine cause CDC conjunction Coverage COVID-19 COVID-19 vaccination COVID-19 vaccine Decline defined dose Effectiveness eligible greater home Immunocompromised include Infection infection with SARS-CoV-2 isolates Johnson & Johnson morbidity and mortality mRNA mRNA vaccine mRNA-1273 network NHSN Nursing nursing home omicron Omicron variant Pfizer-BioNTech Preventing primary dose PROTECT receipt receive reported resident Safety SARS-CoV-2 sequenced Surveillance United States vaccination Vaccine Vaccine-induced immunity Variability variant variants virus Weekly
[DOI] 10.15585/mmwr.mm7118a4 PMC 바로가기 [Article Type] Article

VPipe: an Automated Bioinformatics Platform for Assembly and Management of Viral Next-Generation Sequencing Data

VPipe: 바이러스성 차세대 시퀀싱 데이터의 조립 및 관리를 위한 자동화된 생물정보학 플랫폼

Article

Published on 2022-04-272022-09-11
Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술,

[키워드] addition Analysis assembly automated automated bioinformatics pipeline bioinformatics Bioinformatics analysis bottleneck bottlenecks CDC center Control data set data sets disease control eliminating genome assembly greater high-consequence pathogen Infectious disease Infectious disease surveillance isolate isolates Laboratory management molecular Next-generation sequencing next-generation sequencing (NGS) NGS pathogen Pathogens performed portal powerful tool prevention provide public health Public health response Public health responses Quality control respiratory syncytial virus SARS-CoV-2 secure Sequencing specimen specimens Surveillance System user viral molecular detection. viral outbreak viral pathogens viral sequence viral sequences viruses whole-genome
[DOI] 10.1128/spectrum.02564-21 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

SARS-CoV-2 점 돌연변이 및 삭제 스펙트럼과 다양한 질병 결과와의 연관성

Article

Published on 2022-04-272022-09-11
Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종,

[키워드] Amino acid amino acid substitution amino acid substitutions Amplicon amplicons Analysis association average complexity consensus sequence coronavirus COVID-19 COVID-19 pandemic COVID-19 severity Deletion deletions develop diagnostic disease diversity index Effects functional Genetic variant genetic variants Haplotype infected patients isolate isolates location Mild mild COVID-19 symptoms Mild disease Mild symptom mild symptoms moderate moderate or severe disease mutant mutant spectra mutant spectrum Mutation mutations nasopharyngeal Nsp12 nsp12 (polymerase) Patient patients with moderate phenotypic Point Point mutation polymerase Region RNA RNA virus RNA viruses SARS-CoV-2 selective pressures Sequencing severe COVID-19 severe disease severity significantly significantly higher Spain spike three-dimensional structure ultradeep sequencing. viral pathogenesis virus
[DOI] 10.1128/spectrum.00221-22 PMC 바로가기 [Article Type] Article

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

Research

Published on 2022-04-252022-10-05
Journal: Nature Microbiology [Category] 변종, 유전자 메커니즘,