Juvenile Idiopathic Arthritis and COVID-19 Pandemic: Good Compliance With Treatment, Reluctance to Return to SchoolMedicine Published on 2021-11-122022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] affected age Compliance COVID-19 diagnosed disease-modifying anti-rheumatic drug DMARDs evaluated exceptional Good idiopathic immunosuppressive therapies Juvenile juvenile idiopathic arthritis lockdowns methotrexate Modification National pandemic parent Participants Patient patients patients treated positive Primary outcome questionnaire receiving return SARS-COV-2 infection SARS-CoV-2 pandemic School symptomatic the patient treated Treatment Two patient [DOI] 10.3389/fmed.2021.743815 PMC 바로가기 [Article Type] Medicine
Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritisClinical Science Published on 2021-10-262024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Golimumab intravenous juvenile idiopathic arthritis pharmacokinetics Tumour necrosis factor alpha [DOI] 10.1093/rheumatology/keab021 PMC 바로가기 [Article Type] Clinical Science
A prospective investigation of developmental trajectories of psychosocial adjustment in adolescents facing a chronic condition – study protocol of an observational, multi-center studyStudy Protocol Published on 2021-09-142022-10-04 Journal: BMC Pediatrics [Category] SARS, 임상, [키워드] adaptive adolescents Anxiety assigned baseline bidirectional chronic condition chronic conditions clinical coping coping strategies Coping strategy cystic fibrosis Depression develop developmental diabetes Effects Factor Factors fibrosis Follow-up help Intervention juvenile idiopathic arthritis MONITOR outcome pandemic parallel group participant Patient PHQ-9 positive promote Prospective protective factor Protective factors Psychological Quality of life recruit Resilience resiliency risk Satisfaction Study protocol supplementary material Support trajectory Type 1 diabetes Youth [DOI] 10.1186/s12887-021-02869-9 PMC 바로가기 [Article Type] Study Protocol
Juvenile idiopathic arthritis: from aetiopathogenesis to therapeutic approachesReview Published on 2021-08-232024-09-02 Journal: Pediatric Rheumatology Online Journal [Category] 대상포진, [키워드] Aetiology of juvenile idiopathic arthritis Disease-modifying anti-rheumatic drug treatment juvenile idiopathic arthritis Pathogenesis of juvenile idiopathic arthritis [DOI] 10.1186/s12969-021-00629-8 PMC 바로가기 [Article Type] Review
Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases자가면역 류마티스 질환이 있는 소아 및 청소년의 인간 코로나바이러스에 대한 유리한 항체 반응Clinical and Translational Article Published on 2021-08-142022-09-14 Journal: Med (New York, N.Y.) [Category] MERS, SARS, 임상, 진단, [키워드] Abstract acute respiratory syndrome Adolescent Affect age antibodies antibody Antibody Response Arthritis Autoimmune Cancer Research UK children class-switching collected common-cold comparable Context coronavirus coronavirus disease Coronaviruses COVID-19 COVID-19 pandemic cross-reactive cure dermatomyositis determine difference elevated examined exhibited finding foundation Francis Crick funding HCoV-OC43 HCoV-OC43 spike healthy control human coronavirus Humoral immunity IgG IgG antibody immune immune dysfunction Immunoglobulin Immunosuppression Immunosuppressive treatment infect Infection Inflammatory juvenile idiopathic arthritis lack Lupus Medical Research Council MIS-C myositis NIHR nucleoprotein nucleoprotein of SARS-CoV-2 pandemic Patient patients prevalent raising receive response rheumatic disease Rheumatic diseases risk of COVID-19 SARS-CoV-2 SARS-CoV-2 nucleoprotein SARS-CoV-2 spike seasonal coronavirus sera severe symptom shielding Spike protein Street supported syndrome systemic lupus erythematosus the antibody response Treatment UCLH Wellcome Trust [DOI] 10.1016/j.medj.2021.08.001 PMC 바로가기 [Article Type] Clinical and Translational Article
Inflammatory biomarkers in COVID-19-associated multisystem inflammatory syndrome in children, Kawasaki disease, and macrophage activation syndrome: a cohort studyResearch article Published on 2021-08-012022-10-05 Journal: The Lancet Rheumatology [Category] 바이오마커, [키워드] Acute kidney injury Altered mental status Analysis approach Biomarker center characteristic chemokine children Cincinnati clinical Coagulopathy cohort of patient cohort study Concentration concentrations conditions CXCL9 Deutsche Forschungsgemeinschaft diagnosed Diagnosis eight elevated ELISA enrolled family finding FIVE foundation Frequency funding Hyperinflammatory Hyperinflammatory syndrome IL-18 IL-6 Inflammatory Inflammatory biomarker juvenile idiopathic arthritis Kawasaki disease Laboratory laboratory feature Ligand macrophage activation macrophage activation syndrome management median median age MIS-C motif Myocardial dysfunction nine non-parametric test occur Pathogenesis pathophysiology Patient potentially life-threatening prospective cohort Protein provide S100A12 SARS-COV-2 infection Sensitivity and specificity Seven severity Shock significantly higher skin Stratification Support syndrome systemic inflammatory marker USA was done were assessed [DOI] 10.1016/S2665-9913(21)00139-9 [Article Type] Research article
Editorial: Tocilizumab, a Humanized Therapeutic IL-6 Receptor (IL-6R) Monoclonal Antibody, and Future Combination Therapies for Severe COVID-19사설: Tocilizumab, 인간화 치료 IL-6 수용체(IL-6R) 단클론항체 및 중증 COVID-19에 대한 미래 조합 요법Editorial Published on 2021-07-192022-09-12 Journal: Medical science monitor : international medical jo [Category] 진단, [키워드] antibody approved authorization CAR chimeric antigen receptor clinical development clinical trial combination therapies combination treatment COVID-19 COVID-19 therapy CRS Cytokine release syndrome develop disease drug editorial Efficacy Emergency EUA FDA food Future giant cell arteritis Hospital admission hospitalized patient humanized humanized monoclonal antibody IL-6 IL-6 receptor IL-6R Immunosuppressed individual infected with SARS-CoV-2 juvenile idiopathic arthritis moderate monoclonal antibody Patient Proinflammatory cytokine recovery reduce REMAP-CAP rheumatoid arthritis SARS-COV-2 infection severe COVID-19 severity of COVID-19 supported systemic effect T-cell therapeutic Tocilizumab treat Treatment [DOI] 10.12659/MSM.933973 PMC 바로가기 [Article Type] Editorial
Intravenous administration of anakinra in children with macrophage activation syndromeShort Report Published on 2021-06-292022-10-29 Journal: Pediatric Rheumatology Online Journal [Category] Coronavirus, MERS, SARS, [키워드] addition Administered administration anaphylaxis AST children COVID-19 criteria Critically ill patient Cytokine storm syndrome dysfunction edema ferritin fibrinogen finding hospitalized patient Inflammatory inhibitor Injections intravenous Intravenous administration intravenously juvenile idiopathic arthritis macrophage activation syndrome male MIS-C neurological Platelet reaction recent secondary hemophagocytic lymphohistiocytosis sHLH SLE Subcutaneous syndrome systemic lupus erythematosus therapeutic option treat Treatment [DOI] 10.1186/s12969-021-00585-3 PMC 바로가기 [Article Type] Short Report
COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?Review article Published on 2021-06-012022-10-05 Journal: Translational research : the journal of laboratory [Category] SARS, 유전자 메커니즘, [키워드] Activation amplified anti-cytokine agent Clinical features Coagulopathy complex condition Corticosteroid COVID-19 COVID-19 patient CSS cytokine inhibitors Cytokine storm Cytokine storm syndrome description develop endothelial injury form hemodynamic human pathogen hyperinflammation juvenile idiopathic arthritis macrophage activation multiple organ dysfunction parameter pathophysiology patients patients treated patients with COVID-19 physician Rheumatic diseases SARS-CoV2 subset suggested syndrome therapeutic response therapeutic strategy therapy Treatment with COVID-19 [DOI] 10.1016/j.trsl.2021.03.002 [Article Type] Review article
Seroprevalence of Antibodies against SARS-CoV-2 in Children with Juvenile Idiopathic Arthritis a Case-Control StudyArticle Published on 2021-04-192022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] analyzed anti-SARS-CoV-2 antibody antibody Arthritis caused children control group correlation COVID-19 diagnosed Disease activity disease-modifying antirheumatic drugs drugs evaluated examined Follow-up healthy children healthy subjects humoral immune response idiopathic Inflammatory marker Juvenile juvenile idiopathic arthritis novel coronavirus disease observation Patient pediatric Prevalence rheumatology SARS-CoV-2 SARS-CoV-2 antibody Seroprevalence serum sample Treatment [DOI] 10.3390/jcm10081771 PMC 바로가기 [Article Type] Article