Evaluating the effectiveness of a 6-week hybrid mindfulness-based intervention in reducing the stress among caregivers of patients with dementia during COVID-19 pandemic: protocol of a randomized controlled trialCOVID-19 대유행 기간 동안 치매 환자 간병인의 스트레스 감소에 대한 6주 하이브리드 마음챙김 기반 개입의 효과 평가: 무작위 대조 시험 프로토콜Article Published on 2022-07-192022-09-11 Journal: BMC Psychology [Category] 임상, [키워드] 1:1 Analysis approach attrition benefit Care Caregiver Caregivers component conducted control group control groups Controlled trial COVID-19 COVID-19 pandemic Dementia Effect Effectiveness Eligible participants equation evaluate Evaluating Face-to-face Follow-up follow-up period Frequency Generalized heart rate identify intention-to-treat analysis Intervention intervention group introduced limitations Local Mindfulness-based Neuropsychiatric Online organization Other outcomes outcome parallel-group participant Participants Patient physiological protocol public health qualitative data Quantitative Quantitative data Randomized controlled trial randomly divided RCT receive reducing Research researcher shown Social distancing measure social distancing measures Stress Symptoms therapeutic viability Well-being [DOI] 10.1186/s40359-022-00876-8 PMC 바로가기 [Article Type] Article
Are mRNA based transcriptomic signatures ready for diagnosing tuberculosis in the clinic? – A review of evidence and the technological landscapeReview article Published on 2022-07-152022-10-05 Journal: EBioMedicine [Category] 비임상, [키워드] accelerate addressed advance conducted cut-off defined develop development diagnosing diagnostic diagnostic tests disease evaluate Evidence Fold change funding group groups had no individual Interpretation limit limitations maintain management manuscript MONITOR mRNA mRNA signature New partnership Point-of-care TB diagnostics Population positive predict prognostic progression Prospective Study Sample size shown specificity STOP supported transcriptomic transcriptomics Treatment Tuberculosis working [DOI] 10.1016/j.ebiom.2022.104174 [Article Type] Review article
Novel Lateral Flow-Based Assay for Simple and Visual Detection of SARS-CoV-2 MutationsSARS-CoV-2 돌연변이의 간단하고 시각적인 검출을 위한 새로운 측면 흐름 기반 분석Article Published on 2022-07-142022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] allele amplification asymmetric comparable cycle threshold demonstrated detect detection DNA DNA microarray E484K feature identification impacted Increases K417N L452R Lateral lateral flow lateral flow strip lateral flow strip (LFS) limitations marker molecular molecular diagnostic multiplex Mutation mutations N501Y novel Public health responses real time recommendation reference method Region RNA extract RNA extracts RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 mutations SARS-CoV-2 S gene SARS-CoV-2 variant SARS-CoV-2 variants simple spike mutation spike mutations Surveillance target variant variants of concern virus Visual Visual detection [DOI] 10.3389/fcimb.2022.902914 PMC 바로가기 [Article Type] Article
Inhalable dry powder mRNA vaccines based on extracellular vesiclesResearch article Published on 2022-07-112022-10-05 Journal: Matter [Category] 비임상, [키워드] Bioavailability Bronchiole carriers circumvent COVID-19 death disease distribution dry powder inhalation elicited exhibited Exosome Exosomes extracellular vesicle Extracellular vesicles functional greater IgG illness Immunoglobulin Inhaled limitation limitations Liposome lung mRNA mRNA vaccine NHPs nonhuman primate Protein remained respiratory Respiratory Coronavirus response rodent SARS-CoV-2 secretory IgA SIgA Spike protein stability Therapeutics Vaccine [DOI] 10.1016/j.matt.2022.06.012 [Article Type] Research article
SARS-CoV-2 serological assay and viral testing: a report of professional football settingSARS-CoV-2 혈청학적 분석 및 바이러스 테스트: 프로 축구 환경 보고서Article Published on 2022-07-012022-09-11 Journal: Postgraduate medical journal [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] alternative method association collected comprehension COVID-19 COVID-19 disease COVID-19 testing diagnosing diagnosis of SARS-CoV-2 IgG IgG antibodies IgG antibody IgM inconsistency Infection limitations male management nasopharyngeal swabs Negative PCR participant PCR PCR test PCR-positive Peripheral blood peripheral blood samples positive positive PCR test recovered patients SARS-CoV-2 SARS-CoV-2 IgM SARS-COV-2 infection SARS-CoV-2 PCR test serological Serological assay serological assays Serological testing Serological tests seropositive significantly higher Sports Medicine subjects Swab Symptom symptomatic symptomatic case symptomatic cases tested the disease the SARS-CoV-2 [DOI] 10.1136/postgradmedj-2021-140176 PMC 바로가기 [Article Type] Article
RBD decorated PLA nanoparticle admixture with aluminum hydroxide elicit robust and long lasting immune response against SARS-CoV-2수산화알루미늄이 포함된 RBD 장식 PLA 나노입자 혼합물은 SARS-CoV-2에 대한 강력하고 오래 지속되는 면역 반응을 이끌어냅니다.Article Published on 2022-07-012022-09-12 Journal: European journal of pharmaceutics and biopharmaceu [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome aluminum antibody Antibody Response Antigen binding caused Characteristics circumvent Combination coronavirus COVID-19 COVID-19 vaccine develop E. coli elicit elicited expressed expression generate global pandemic hydroxide immune response immunization lactic acid limitations long-lasting mammalian memory Memory antibody response mimicking neutralization neutralize plaque Polymeric nanoparticles Protein-subunit vaccine provided RBD Receptor binding domain Result robust SARS-CoV-2 SARS-CoV-2 vaccine secondary antibody subunit Subunit vaccine Th1 Th2 Vaccine vaccine production virus infection Virus neutralization [DOI] 10.1016/j.ejpb.2022.05.008 PMC 바로가기 [Article Type] Article
Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review임상 샘플에서 SARS-CoV-2 검출을 위한 전기화학 기반 감지 접근 방식 활용: 검토Review Published on 2022-06-292022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 advance Blood clinical clinical samples coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 detection diagnose diagnostic diagnostic methods diagnostic tests diagnostics early treatment electrochemical biosensor employment equipment healthcare worker Healthcare workers in viral individuals infected individuals Infection Isolation limit limitations microfluidic electrochemical devices miniaturised electrochemical sensor Nasopharyngeal swab operation platform POC point of care point of care (PoC) rapid response readiness respiratory review Saliva SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus simplicity Spread standard diagnostic test standard diagnostic tests transducing Viral [DOI] 10.3390/bios12070473 PMC 바로가기 [Article Type] Review
Meaningful Use of Pathogen Genomic Data병원체 게놈 데이터의 의미 있는 사용Comment Published on 2022-06-282022-09-11 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis bioinformatics Characteristics collected contributing to epidemiological Factor failure genomic Genomic analysis genomic data genomic databases Genomic epidemiology Gill Health Hedge implication instances limitations lineages mBio methicillin methicillin-resistant Staphylococcus aureus MRSA pathogen Pathogens phenotypic Population population genomics powerful tool SARS-CoV-2 Staphylococcus Staphylococcus aureus term These data utility Wilson [DOI] 10.1128/mbio.00311-22 PMC 바로가기 [Article Type] Comment
Smartphone apps in the COVID-19 pandemic Reviews Published on 2022-06-202022-10-05 Journal: Nature biotechnology [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] 1918 influenza Contact tracing COVID-19 COVID-19 pandemic Epidemics Epidemiology Evidence globe Health illiteracy limitations Nasopharyngeal swab outbreak outcome pandemic PCR test physical distancing Smartphone while [DOI] 10.1038/s41587-022-01350-x [Article Type] Reviews
Advances in nucleic acid amplification techniques (NAATs): COVID-19 point-of-care diagnostics as an exampleReview article Published on 2022-06-012022-10-05 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] advance amplification Bio-detection chain Characteristics Circle clinical settings Combination COVID-19 COVID-19 pandemic Diagnosis diagnostics Efficiency example feature greater limitations Molecular diagnosis NAAT nucleic acid amplification Nucleic acid amplification technologies offer PCR POCT point-of-care point-of-care diagnostics RCA reaction REcombinase Research Rolling RPA SARS-CoV-2 sensitivity Sensitivity and specificity specificity stability unique [DOI] 10.1016/j.bios.2022.114109 [Article Type] Review article