low molecular weight – Page 3 – Communicable Diseases Research

[COVID-19-induced coagulopathy and thrombosis manifestations]

[COVID-19로 인한 응고장애 및 혈전증 증상]

Review

Published on 2021-10-012022-09-11
Journal: Radiologe [Category] MERS, SARS, 진단, 치료기술,

A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight Heparins for Mortality Reduction in 32,688 COVID-19 Patients

Pharmacology

Published on 2021-09-022022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] 95% CI 95% confidence interval Activation all-cause mortality anticoagulation bleeding coronavirus disease COVID-19 COVID-19 patients dose effective Effectiveness Efficacy Endpoint evaluated hazard heparin heparin treatment heparins higher risk Hospital stay hospitalized COVID-19 patients increased risk LMWH LOS low molecular weight major bleeding Meta-analysis Mortality no difference Observational cohort study Patient patients performed potential therapy Prophylactic prophylactic dose Randomized controlled trial Ratio RCT reduced reducing mortality Registration reported review SARS-CoV2 secondary subgroup analysis systematic review therapeutic dose Thromboembolism Treatment unfractionated heparin was performed weight
[DOI] 10.3389/fphar.2021.698008 PMC 바로가기 [Article Type] Pharmacology

Remdesivir in Severe COVID-19 and Non-Invasive Ventilation: A Real-Life Experience

Article

Published on 2021-08-272022-10-31
Journal: International journal for equity in health [Category] COVID-19,

[키워드] administer Administered Adverse drug reaction Antibiotics Antiviral antiviral drug approval ARDS Clinical improvement Clinical sign Cohort collected compassionate use Course COVID-19 CPAP Data collection defined demonstrated discharge enrolled experience Gas exchange hazard ratio Hospitalization HRCT Infection Inflammation Laboratory low molecular weight lung damage lung involvement Major marker moderate Mortality NIV non-invasive ventilation Older outcome overall mortality Oxygen therapy oxygen-support pandemic parameter Patient patients hospitalized performed radiological receiving recorded Result SARS-CoV2 severe COVID-19 severity single-center study Steroids subject Support Symptoms tested therapeutic therapy therapy for COVID-19 Topic Treatment trials Ventilation was recorded
[DOI] 10.3390/healthcare9091108 PMC 바로가기 [Article Type] Article

Point of care ultrasound (POCUS) in diagnosis of proximal deep vein thrombosis among COVID-19 hospitalized patients with a high rate of low molecular weight heparin prophylaxis

저분자량 헤파린 예방치료율이 높은 코로나19 입원환자 근위심부정맥혈전증 진단 시 현장진료초음파(POCUS)

Case Reports

Published on 2021-08-272022-09-11
Journal: Medicina clínica [Category] SARS, 치료기술,

[키워드] anticoagulation Care clinical clinical and laboratory features Complication COVID-19 critical condition Deep vein Deep vein thrombosis detect determine Diagnosis discharged DVT Ecografía Embolia pulmonar English helping heparin Heparina de bajo peso molecular hospitalized COVID-19 patients hospitalized patient ICU intensive care intensive care unit Laboratory features limb LMWH low molecular weight low molecular weight heparin Low-molecular-weight heparin Lower lower limb molecular notable outcome pacientes hospitalizado Patient performed planta Point point-of-care popliteal positive Prescriptions Prevalence Prophylaxis proximal pulmonary Pulmonary embolism receiving screened Screening Sin Spanish suffered thrombosis thrombotic complication Thrombotic complications treat Trombosis venosa profunda Ultrasonography ward was performed were assessed with COVID-19
[DOI] 10.1016/j.medcli.2021.01.012 PMC 바로가기 [Article Type] Case Reports

Kidney involvement and histological findings in two pediatric COVID-19 patients

두 소아 코비드 9 환자의 신장 참여 및 조직 학적 소견

Case Reports

Published on 2021-08-182022-09-10
Journal: Pediatric Nephrology (Berlin, Germany) [Category] MERS, SARS, 진단, 치료기술,

[키워드] Analysis Atypical bleb children clinical picture Complete COVID-19 patient creatinine crescentic glomerulonephritis diagnosed electron microscopy elevated Glomerulonephritis glycosuria histological Hypouricemia IgA Immunosuppression infectious agent infectious agents Inflammatory initial initiated intensification Interstitial nephritis kidney Kidney biopsy kidney damage Laboratory low molecular weight medication medications Microscopy Patient pediatric Pediatric case Pediatric patient Pediatric patients Proteinuria reported responsible Result rhinitis SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection sclerosis serum creatinine skin rash steroid steroid therapy therapy titre Trigger tubular cell tubular cells Tubular damage Urine Vasculitis Virus-like particle virus-like particles weakness weight loss worsening
[DOI] 10.1007/s00467-021-05212-7 PMC 바로가기 [Article Type] Case Reports

Role of Peptides in Diagnostics

진단에서 펩티드의 역할

Review

Published on 2021-08-172022-09-12
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단,

[키워드] Analysis Antigen applicability biofluids Blood Cancer Chemokine receptor clearance Computed tomography COVID-19 diagnostic diagnostics disease Diseases ELISA enzyme enzyme-linked immunosorbent assay evaluated gastrin Gastrin-releasing peptide imaging diagnostic immunogenicity information integrin interleukin interleukin 2 Lateral flow device low molecular weight membrane Microarray molecular molecular imaging molecular weight non-imaging diagnostic penetration peptide peptide-based peptides pet platform point-of-care positron emission Positron emission tomography probe probes Prostate purity radiolabeled receptor Receptor imaging receptors role single-photon emission computed tomography Somatostatin specificity SPECT stability synthetic peptide synthetic peptides tissue tomography
[DOI] 10.3390/ijms22168828 PMC 바로가기 [Article Type] Review

Sirolimus in a Renal Transplant Recipient Infected With COVID-19: A Blessing in Disguise?

Infectious Disease

Published on 2021-08-112022-10-31
Journal: Cureus [Category] COVID-19,

A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial

SARS Cov-2 감염으로 입원한 환자에서 아스피린, 아토르바스타틴, 니코란딜을 사용한 삼중 요법의 효능과 안전성을 평가하기 위한 무작위 공개 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-07-152022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 ACHE Acute coronary syndrome Acute kidney injury acute renal failure adequate hydration adjuvant therapy Admission allergy ALT/AST Altered mental status Anti-inflammatory anticoagulation antipyretics Antithrombotic approved ARDS Aspirin AST/ALT atorvastatin bleeding Blinding block randomization Breastfeeding brown urine change characterized clinical clinical feature Clinical features Coagulopathy college Combination comorbid condition comorbid conditions comparator conducted control group coronary syndrome Corticosteroid Corticosteroids cough COVID-19 CPK creatine creatine kinase creatinine CRP current therapy Dexamethasone dissemination dose drug dysfunction Dyspnoea dysregulation effective Efficacy and safety element Endothelial dysfunction enrolled ethical committee evaluate excluded ferritin Fever followed by greater heparin hepatotoxicity Hospital admission hospital discharge Hospital mortality Hospital stay hospitalised patient Hospitalised patients hyperbilirubinemia hypoxia ICMR IEC immune dysregulation immunomodulatory impaired consciousness in-hospital mortality India Inflammation Inflammatory marker inflammatory markers Intervention intervention group intolerance intravenous Intravenous remdesivir invasive limit liver low molecular weight low molecular weight heparin management marker mechanical ventilation medication medications moderate muscle ache myalgia Myoglobin Myopathy myositis national guidelines Nicorandil Non-invasive number objective once daily Open-label open-label trial outcome oxygen Oxygen requirement oxygen support participant pathophysiologic pathophysiology Patient Platelet Platelet count Pneumonia positive Pregnancy Primary outcome progression protocol raised Rajendra Prasad Randomised control trial randomization randomize Randomized Randomized controlled trial randomly divided receive recruitment reducing mortality Registered registry Remdesivir renal failure reported respiratory rate rhabdomyolysis room air RT-PCR safety endpoint safety endpoints Sample size SARS-CoV-2 infected patient SARS-COV-2 infection Schematic screened Secondary outcomes Sepsis serum serum markers severe disease Shock significant interaction SpO2 Standard Standard of care starting dose statin statins Study design Study protocol substrates supplementary material Symptom Symptomatic treatment Tablet therapeutic therapeutic agent therapy thrombocytopenia Treatment Trial Trial registration two-arm parallel ULN Urine weakness website
[DOI] 10.1186/s13063-021-05361-y PMC 바로가기 [Article Type] Letter

Intensive care for seriously ill patients affected by novel coronavirus sars – CoV – 2: Experience of the Crema Hospital, Italy

신종 코로나바이러스 사스 감염 중환자 집중치료 - CoV - 2: 이탈리아 크레마 병원 경험

Article

Published on 2021-07-012022-09-11
Journal: The American journal of emergency medicine [Category] MERS, SARS, 진단, 치료기술, 치료제,

[키워드] 19 outbreak acute lung damage Acute respiratory infection Admission admitted to ICU Affect affected age alterations analyzed Antibiotic therapy Antiviral appear appearance ARDS assistance available data average average age barotrauma barotrauma mechanism bilateral pneumonia blood chemistry blood gas blood gas analysis Care caused cerebral hemorrhage Chest close contact Comorbidities Comorbidity Complication complications condition conditions consecutive patient cortisone CoV CoV - 2 COVID criterion Critical D-dimer death Deceased Department died disease disease outbreak distribution dosage effort Emergency emergency department emergency room Encephalitis event events Evidence experience flu forms gas analysis general condition gold heart disease help heparin heterogeneity heterogeneous high mortality Hospitalization Hydroxychloroquine hydroxychloroquine therapy hypoxia ICU identify IL6 impairment Infection intensive care intensive care unit Intubated intubated patients intubation ischemic heart disease Italy lesion lesions less liver liver failure low molecular weight lung damage majority male management Mechanical mechanical ventilation mechanism medium moderate monoclonal antibody Mortality mortality data multi-organ failure multiple comorbidities multiple comorbidity myopathies neurological New coronavirus non-invasive ventilation Novel coronavirus occurred Older onset of symptom operators outbreak oximetry pandemic parameter Pathogens pathology pathway Patient patients patients died patients with SARS phenotype Prevalence Prevention and control Prognosis Prognostic factor Protective protocol protocols recruited recruitment renal renal failure Research resource respiratory respiratory distress respiratory droplet Respiratory droplets respiratory infection respiratory insufficiency resulting SARI SARS Sepsis seriously ill patient severe hypoxia Severe respiratory distress shown sudden onset Support Surveillance survival surviving patient surviving patients survivor Survivors Symptom syndrome systemic disease the timing therapy thromboembolic thromboembolic complication tracheal Transmission Treatment venous Ventilation Viral was performed worsening
[DOI] 10.1016/j.ajem.2020.08.005 PMC 바로가기 [Article Type] Article

Acute Limb Ischemia in Hospitalized COVID-19 Patients

Observational Study

Published on 2021-07-012022-10-05
Journal: Annals of vascular surgery [Category] 임상,

[키워드] Admission age cardiovascular systems cause clinical suspicion co-morbidity collected Computed tomography consecutive patient COVID-19 COVID-19 diagnosis cross-sectional death demographics diagnosed diagnosis of COVID-19 discharge examined healthy hematologic hospital discharge Hospital stay Hospitalization Hospitalized hospitalized patient increased risk Infection intensive care IQR Ischemia limb low molecular weight median median age Mortality multiple organ multisystemic disorder occurred outcome Patient patients receiving Record reported required resolved single-center study period subsequent surgical Survivors symptom onset systemic anticoagulation Thromboembolic event Thromboembolic events Thromboprophylaxis thrombosis Two patient Venous Thromboembolism widespread with COVID-19 women
[DOI] 10.1016/j.avsg.2021.03.003 PMC 바로가기 [Article Type] Observational Study